Affiliation: The University of Texas
- Lifestyle intervention development study to improve physical function in older adults with cancer: outcomes from Project LEADWendy Demark-Wahnefried
School of Nursing, Department of Surgery, Older Americans Independence Center, Duke University Medical Center, Durham, NC 27710, USA
J Clin Oncol 24:3465-73. 2006..Declines in physical functioning (PF) among elderly cancer patients threaten quality of life and the ability to maintain independence. Adherence to healthy lifestyle behaviors may prevent functional decline...
- Main outcomes of the FRESH START trial: a sequentially tailored, diet and exercise mailed print intervention among breast and prostate cancer survivorsWendy Demark-Wahnefried
Duke School of Nursing, Duke Comprehensive Cancer Center, and Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA
J Clin Oncol 25:2709-18. 2007..The FRESH START trial tested the efficacy of sequentially tailored versus standardized mailed materials on improving cancer survivors' diet and exercise behaviors...
- Flaxseed supplementation (not dietary fat restriction) reduces prostate cancer proliferation rates in men presurgeryWendy Demark-Wahnefried
Division of Cancer Prevention and Population Sciences, The University of Texas M D Anderson Cancer Center, P O Box 301439, Unit 1330, Houston, TX 77230 1439, USA
Cancer Epidemiol Biomarkers Prev 17:3577-87. 2008..Dietary factors are postulated to influence the development and progression of prostate cancer. Low-fat diets and flaxseed supplementation may offer potentially protective strategies...
- Folic acid supplementation before and during pregnancy in the Newborn Epigenetics STudy (NEST)Cathrine Hoyo
Department of Community and Family Medicine and Program of Cancer Detection, Prevention and Control, Duke University, PO Box 104006, Durham, NC 27710, USA
BMC Public Health 11:46. 2011..The primary objective is to estimate the proportion of women taking folic acid (FA) doses exceeding the TUL before and during pregnancy, and to identify correlates of high FA use...
- Promoting healthy lifestyles in older cancer survivors to improve health and preserve functionWendy Demark-Wahnefried
University of Texas, M D Anderson Cancer Center, Houston, TX 77030, USA
J Am Geriatr Soc 57:S262-4. 2009..Larger trials, such as Reach-out to ENhancE Wellness in Older Survivors, have recently produced compelling data...
- Results of a diet/exercise feasibility trial to prevent adverse body composition change in breast cancer patients on adjuvant chemotherapyWendy Demark-Wahnefried
Department of Behavioral Sciences, University of Texas, M D Anderson Cancer Center, Houston, TX 77030, USA
Clin Breast Cancer 8:70-9. 2008..Exercise interventions can prevent these changes, but time and travel pose barriers to participation. The Survivor Training for Enhancing Total Health (STRENGTH) trial assessed the feasibility and impact of 2 home-based interventions...
- Overcoming challenges in designing and implementing a phase II randomized controlled trial using a presurgical model to test a dietary intervention in prostate cancerWendy Demark-Wahnefried
Division of Cancer Prevention and Control Department of Behavioral Science, MD Anderson Cancer Center, Houston, TX, USA
Clin Trials 5:262-72. 2008..Despite the many strengths of presurgical models, there are practical issues and challenges that arise when using this approach...
- Dietary interventions in prostate cancerWendy Demark-Wahnefried
Division of Cancer Prevention and Population Sciences, MD Anderson Cancer Center, University of Texas, 1155 Pressler Street, CPB 3 3245, Houston, TX 77030, USA
Curr Urol Rep 9:217-25. 2008....
- Long-term physical activity outcomes of home-based lifestyle interventions among breast and prostate cancer survivorsAllison J Ottenbacher
University of Texas Memorial Hermann, Center for Healthcare Quality and Safety, Houston, TX, USA
Support Care Cancer 20:2483-9. 2012..The goal of this study was to evaluate whether or not increased levels of moderate to vigorous physical activity (MVPA) were maintained by cancer survivors 1 year after receipt of two home-based interventions...
- Extant health behaviors and uptake of standardized vs tailored health messages among cancer survivors enrolled in the FRESH START trial: a comparison of fighting-spirits vs fatalistsAnna V Wilkinson
Division of Epidemiology, Human Genetics and Environmental Science, University of Texas School of Public Health, Austin Regional Campus, Austin, TX, USA
Psychooncology 21:108-13. 2012....
- Exercise among breast and prostate cancer survivors--what are their barriers?Allison J Ottenbacher
University of Texas School of Public Health, Houston, TX, USA
J Cancer Surviv 5:413-9. 2011..The purpose of this paper is to identify and compare exercise barriers among cancer survivors, both cross-sectionally and longitudinally as they undergo home-based behavioral interventions...
- Effect of low-fat diets on plasma levels of NF-κB-regulated inflammatory cytokines and angiogenic factors in men with prostate cancerJohn V Heymach
Department of Thoracic Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, 77030, USA
Cancer Prev Res (Phila) 4:1590-8. 2011..These results suggest that a LF diet without flaxseed may reduce levels of specific inflammatory CAFs and suggests that the NF-κB pathway may be a mediator of these changes...
- Lifestyle interventions to reduce cancer risk and improve outcomesWendy Demark-Wahnefried
Department of Behavioral Science, University of Texas M D Anderson Cancer Center, Houston, Texas 77230, USA
Am Fam Physician 77:1573-8. 2008....
- Associations between leisure-time physical activity and health-related quality of life among adolescent and adult survivors of childhood cancersRaheem J Paxton
Department of Health Disparities Research, The University of Texas M D Anderson Cancer Center, Houston, TX 77230 1439, USA
Psychooncology 19:997-1003. 2010..We thus explored the relationship between physical activity (PA) and HRQOL among survivors of childhood cancer...
- Cancer-specific concerns and physical activity among recently diagnosed breast and prostate cancer survivorsAllison Ottenbacher
1Texas Prevention Institute University of North Texas Health Science Center, Fort Worth, TX, USA
Integr Cancer Ther 12:206-12. 2013..Additionally, participants reporting greater levels of PA will also report fewer cancer-specific concerns...
- Promoting a healthy lifestyle among cancer survivorsWendy Demark-Wahnefried
Department of Behavioral Science, The University of Texas MD Anderson Cancer Center, 1155 Herman P Pressler, CPPB3 3245, Houston, TX 77030, USA
Hematol Oncol Clin North Am 22:319-42, viii. 2008....
- Agreement between a brief mailed screener and an in-depth telephone survey: observations from the Fresh Start studyDenise Clutter Snyder
Department of Surgery, Center for the Study of Aging and Human Development, Duke University Medical Center, Box 3003, Durham, NC 27710, USA
J Am Diet Assoc 104:1593-6. 2004..Decisions to use brief screening instruments should be based on available resources and tolerance for misclassification...
- Differences in baseline characteristics and outcomes at 1- and 2-year follow-up of cancer survivors accrued via self-referral versus cancer registry in the FRESH START Diet and exercise trialDenise Clutter Snyder
School of Nursing, Duke University Medical Center, Box 3322, Room 1057, 311 Trent Drive, Durham, NC 27710
Cancer Epidemiol Biomarkers Prev 17:1288-94. 2008..05). Several differences exist between self-referred and registry-ascertained participants, including motivation to respond to standardized educational materials, which appears significantly greater in self-referred populations...
- Can lifestyle modification increase survival in women diagnosed with breast cancer?Cheryl L Rock
Department of Family and Preventive Medicine, University of California, San Diego, La Jolla, CA 92093 0901, USA
J Nutr 132:3504S-3507S. 2002..The results of these studies will contribute to understanding the roles of diet and physical activity in the progression of breast cancer...
- Effect of flaxseed supplementation on prostatic carcinoma in transgenic miceXu Lin
Division of Urologic Surgery, Department of Surgery, and Center for Aging and Human Development, Duke University Medical Center, Durham, North Carolina 27710, USA
Urology 60:919-24. 2002..45 +/- 0.14 versus 3.3 +/- 0.31 (P <0.0001). Similar differences were seen after 30 weeks of treatment. CONCLUSIONS: A diet supplemented with 5% flaxseed inhibits the growth and development of prostate cancer in the TRAMP model...
- The Diet Quality Index-Revised: a tool to promote and evaluate dietary change among older cancer survivors enrolled in a home-based intervention trialDenise Clutter Snyder
School of Nursing, Duke University, Box 3322 Duke University Medical Center, Durham, NC 27710, USA
J Am Diet Assoc 107:1519-29. 2007..To utilize the Diet Quality Index-Revised (DQI-R) as a framework for delivering and evaluating an intervention to improve overall diet quality among older cancer survivors...
- Design of FRESH START: a randomized trial of exercise and diet among cancer survivorsWendy Demark-Wahnefried
Duke University Medical Center DUMC, Durham, NC 27710, USA
Med Sci Sports Exerc 35:415-24. 2003....
- Dietary intervention in the management of prostate cancerWendy Demark-Wahnefried
School of Nursing and Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710, USA
Curr Opin Urol 17:168-74. 2007..This review integrates recent reports related to the dietary management of prostate cancer with the existing body of science in an effort to best inform practicing clinicians...
- Leading the Way in Exercise and Diet (Project LEAD): intervening to improve function among older breast and prostate cancer survivorsWendy Demark-Wahnefried
Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA
Control Clin Trials 24:206-23. 2003..In reporting our methods, we hope to give others "a leg up," so that they can hurdle with greater ease the barriers we experienced, and thus advance the field more rapidly...
- Carbohydrate restriction, prostate cancer growth, and the insulin-like growth factor axisStephen J Freedland
Department of Surgery, Durham VA Medical Center, Durham, North Carolina 27710, USA
Prostate 68:11-9. 2008..Recent evidence suggests carbohydrate intake may influence prostate cancer biology. We tested whether a no-carbohydrate ketogenic diet (NCKD) would delay prostate cancer growth relative to Western and low-fat diets in a xenograft model...
- Cancer survival: time to get moving? Data accumulate suggesting a link between physical activity and cancer survivalWendy Demark-Wahnefried
J Clin Oncol 24:3517-8. 2006
- Pilot study to explore effects of low-fat, flaxseed-supplemented diet on proliferation of benign prostatic epithelium and prostate-specific antigenWendy Demark-Wahnefried
Division of Urologic Surgery, Duke University Medical Center, Durham, North Carolina 27710, USA
Urology 63:900-4. 2004..A randomized controlled trial is needed to determine whether flaxseed supplementation, a low-fat diet, or a combination of the two regimens may be of use in controlling overall prostatic growth...
- Nutrition and the cancer survivor: evidence to guide oncology nursing practiceMark Toles
Duke University School of Nursing, Durham, NC, USA
Semin Oncol Nurs 24:171-9. 2008....
- Interest in healthy diet and physical activity interventions peripartum among female partners of active duty militaryTruls Ostbye
Department of Community and Family Medicine, Duke University Medical Center. Box 2914, Durham, NC 27710, USA
Mil Med 168:320-5. 2003..Interest was high for interventions that promote physical activity and facilitate social interaction. Based on these results, a postpartum exercise intervention is being designed for female partners of active duty soldiers...
- Childhood cancer survivors' perceived barriers to improving exercise and dietary behaviorsWhitney D Arroyave
School of Nursing, Duke University, Durham, NC, USA
Oncol Nurs Forum 35:121-30. 2008..To determine childhood cancer survivors' barriers to increasing exercise and consuming less fat and more fruits and vegetables, whole grains, and calcium-rich foods...
- Promoting health and physical function among cancer survivors: potential for prevention and questions that remainWendy Demark-Wahnefried
Duke University Medical Center, School of Nursing and Department of Surgery, Durham, NC 27710, USA
J Clin Oncol 24:5125-31. 2006....
- Nutrition-related issues for the breast cancer survivorWendy Demark-Wahnefried
Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA
Semin Oncol 30:789-98. 2003..Furthermore, diets high in vegetables, fruit, whole grains, and low-fat dairy foods, and low in saturated fat, may help to lower overall disease risk in this population...
- No difference in response rate to a mailed survey among prostate cancer survivors using conditional versus unconditional incentivesBrian R Evans
Department of Biostatistics and Bioinformatics, Duke University Medical Center, Durham, North Carolina 27710, USA
Cancer Epidemiol Biomarkers Prev 13:277-8. 2004..Other means, however, appear necessary to achieve acceptable response rates among minority group cancer survivors...
- Nutrition and survival after the diagnosis of breast cancer: a review of the evidenceCheryl L Rock
Department of Family and Preventive Medicine, Cancer Prevention and Control Program, Dept 901, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093 0901, USA
J Clin Oncol 20:3302-16. 2002..To review and summarize evidence from clinical and epidemiologic studies that have examined the relationship between nutritional factors, survival, and recurrence after the diagnosis of breast cancer...
- Erythropoietin and erythropoietin receptor expression in human prostate cancerMurat O Arcasoy
Department of Medicine, Duke University Medical Center, Durham, NC27710, USA
Mod Pathol 18:421-30. 2005..The coexpression of erythropoietin receptor and its ligand erythropoietin in human prostate cancer cells suggests the potential for growth regulation by erythropoietin-erythropoietin receptor in an autocrine or paracrine manner...
- IGF1 (CA)19 repeat and IGFBP3 -202 A/C genotypes and the risk of prostate cancer in Black and White menJoellen M Schildkraut
Program of Cancer Prevention, Detection and Control Research, Department of Community and Family Medicine, Duke University Medical Center, Durham, NC, USA
Cancer Epidemiol Biomarkers Prev 14:403-8. 2005..Further research is needed to confirm these findings...
- Survivors of childhood cancer and their guardiansWendy Demark-Wahnefried
Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710, USA. demar001mc.duke.edu
Cancer 103:2171-80. 2005..Health promotion interventions aimed at areas of interest and delivered through acceptable channels have the potential to improve long-term health and function of this vulnerable population...
- Response rates to a mailed survey targeting childhood cancer survivors: a comparison of conditional versus unconditional incentivesPhilip M Rosoff
Division of Hematology Oncology, Department of Pediatrics, Duke University Medical Center, 222 Bell Building, Trent Drive, Durham, NC 27710, USA
Cancer Epidemiol Biomarkers Prev 14:1330-2. 2005..A study was undertaken among childhood cancer survivors and their parents to determine if response rate to a mailed survey differed with provision of immediate versus delayed incentives...
- Supplement use among men with prostate cancerJeremy B Wiygul
Division of Urology, Duke University Medical Center, Durham, North Carolina 27710, USA
Urology 66:161-6. 2005..To characterize supplement use within a sample population of men diagnosed with prostate cancer...
- Nutrition and physical activity during and after cancer treatment: an American Cancer Society guide for informed choicesColleen Doyle
American Cancer Society, Atlanta, GA, USA
CA Cancer J Clin 56:323-53. 2006....
- Diet, exercise, and complementary therapies after primary treatment for cancerLee W Jones
Department of Surgery, Duke University Medical Center, Durham, NC, USA
Lancet Oncol 7:1017-26. 2006..Overall, this review provides important information to oncology care providers who counsel their patients on preventive lifestyle practices to maximise health and longevity after a diagnosis of cancer...
- Grade-specific prostate cancer associations of IGF1 (CA)19 repeats and IGFBP3-202A/C in blacks and whitesCathrine Hoyo
Department of Community and Family Medicine, Hanes House Room 347, Trent Drive, Box 2914, Medical Center, Duke University Medical Center, Durham, NC 27710, USA
J Natl Med Assoc 99:718-22. 2007..If confirmed in larger studies, these findings support the hypothesis that the association between IGFBP3 C allele and prostate cancer is grade specific in both ethnic groups...
- Move onward, press forward, and take a deep breath: can lifestyle interventions improve the quality of life of women with breast cancer, and how can we be sure?Wendy Demark-Wahnefried
J Clin Oncol 25:4344-5. 2007
- Enterolactone induces apoptosis in human prostate carcinoma LNCaP cells via a mitochondrial-mediated, caspase-dependent pathwayLi Hua Chen
Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, and Graduate School of the Chinese Academy of Sciences, Shanghai, China
Mol Cancer Ther 6:2581-90. 2007..Mechanistic studies suggested roles for Akt, GSK-3beta, MDM2, and p53 in enterolactone-dependent apoptosis. Our findings encourage further studies of enterolactone as a promising chemopreventive agent against prostate cancer...
- Effects of a flaxseed-derived lignan supplement in type 2 diabetic patients: a randomized, double-blind, cross-over trialAn Pan
Key Laboratory of Systems Biology, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences and Graduate School of the Chinese Academy of Sciences, Shanghai, China
PLoS ONE 2:e1148. 2007..The study aimed to investigate the effect of a flaxseed-derived lignan supplement on glycemic control, lipid profiles and insulin sensitivity in type 2 diabetic patients...
- Nutrition and physical activity during and after cancer treatment: an American Cancer Society guide for informed choicesJean K Brown
University at Buffalo School of Nursing, The State University of New York, Buffalo, NY, USA
CA Cancer J Clin 53:268-91. 2003....
- PROMOTING HEALTH IN PROSTATE & BREAST CANCERWendy Demark Wahnefried; Fiscal Year: 2005..If effective, this program could be modified, easily disseminated & used in a variety of health care settings, thus having broad public health impact. ..
- Prostate Cancer: Impact of Fat & Flaxseed Modified DietWendy Demark Wahnefried; Fiscal Year: 2005..This research has the potential to expand the scope of complementary treatment offered for prostate cancer, and may provide a solid foundation for efforts aimed at prevention. ..
- PROMOTING HEALTH IN PROSTATE & BREAST CANCERWendy Demark Wahnefried; Fiscal Year: 2004..If effective, this program could be modified, easily disseminated & used in a variety of health care settings, thus having broad public health impact. ..
- RENEW Research-out to Enhance Wellness Older SurvivorsWendy Demark Wahnefried; Fiscal Year: 2007..abstract_text> ..