Ivan E de Araujo

Summary

Affiliation: The John B. Pierce Laboratory
Country: USA

Publications

  1. ncbi request reprint Food reward in the absence of taste receptor signaling
    Ivan E de Araujo
    Department of Neurobiology, Duke University Medical Center, Durham, NC 27710, USA
    Neuron 57:930-41. 2008
  2. ncbi request reprint Metabolic sensing in brain dopamine systems
    Ivan E de Araujo
    The John B Pierce Laboratory and Department of Psychiatry, Yale University School of Medicine, 290 Congress Avenue, New Haven, CT 06519, USA
    Results Probl Cell Differ 52:69-86. 2010
  3. ncbi request reprint Expanding the brain glucosensing territory
    Ivan E de Araujo
    The J B Pierce Laboratory, 290 Congress Ave, New Haven, CT 06519, USA Department of Psychiatry, Yale University School of Medicine, 300 George Street, Suite 901, New Haven, CT 06511, USA Department of Physiology, Yale University School of Arts and Sciences, 320 York Street, New Haven, CT 06511, USA Electronic address
    Cell Metab 20:933-5. 2014
  4. pmc The insular cortex controls food preferences independently of taste receptor signaling
    Albino J Oliveira-Maia
    Departamento de Biologia Experimental, Faculdade de Medicina, Universidade do Porto Porto, Portugal
    Front Syst Neurosci 6:5. 2012
  5. pmc Sweet taste signaling and the formation of memories of energy sources
    Ivan E de Araujo
    The John B Pierce Laboratory, Department of Psychiatry, Yale University School of Medicine New Haven, CT, USA
    Front Syst Neurosci 5:99. 2011
  6. pmc Sweet taste signaling functions as a hypothalamic glucose sensor
    Xueying Ren
    The John B Pierce Laboratory New Haven, CT, USA
    Front Integr Neurosci 3:12. 2009
  7. pmc Glucose utilization rates regulate intake levels of artificial sweeteners
    Luis A Tellez
    I E de Araujo The John B Pierce Laboratory and Yale University School of Medicine, 290 Congress Avenue, New Haven, CT 06519, USA or
    J Physiol 591:5727-44. 2013
  8. pmc Metabolic regulation of brain response to food cues
    Ivan E de Araujo
    The John B Pierce Laboratory, New Haven, CT 06519, USA
    Curr Biol 23:878-83. 2013
  9. pmc The gut-brain dopamine axis: a regulatory system for caloric intake
    Ivan E de Araujo
    The John B Pierce Laboratory, New Haven, CT 06519, USA
    Physiol Behav 106:394-9. 2012
  10. pmc The gustatory cortex and multisensory integration
    I E de Araujo
    The John B Pierce Laboratory and Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06519, USA
    Int J Obes (Lond) 33:S34-43. 2009

Collaborators

Detail Information

Publications21

  1. ncbi request reprint Food reward in the absence of taste receptor signaling
    Ivan E de Araujo
    Department of Neurobiology, Duke University Medical Center, Durham, NC 27710, USA
    Neuron 57:930-41. 2008
    ..Our findings suggest that calorie-rich nutrients can directly influence brain reward circuits that control food intake independently of palatability or functional taste transduction...
  2. ncbi request reprint Metabolic sensing in brain dopamine systems
    Ivan E de Araujo
    The John B Pierce Laboratory and Department of Psychiatry, Yale University School of Medicine, 290 Congress Avenue, New Haven, CT 06519, USA
    Results Probl Cell Differ 52:69-86. 2010
    ..In particular, it suggests a role for brain dopamine reward systems as metabolic sensors, allowing for signals generated by the metabolic utilization of nutrients to regulate neurotransmitter release and food reinforcement...
  3. ncbi request reprint Expanding the brain glucosensing territory
    Ivan E de Araujo
    The J B Pierce Laboratory, 290 Congress Ave, New Haven, CT 06519, USA Department of Psychiatry, Yale University School of Medicine, 300 George Street, Suite 901, New Haven, CT 06511, USA Department of Physiology, Yale University School of Arts and Sciences, 320 York Street, New Haven, CT 06511, USA Electronic address
    Cell Metab 20:933-5. 2014
    ..In this issue, Garfield and colleagues (2014) demonstrate that cholecystokinin-expressing neurons in the rodent parabrachial nucleus function as glucosensors that counter-regulate hypoglycemia. ..
  4. pmc The insular cortex controls food preferences independently of taste receptor signaling
    Albino J Oliveira-Maia
    Departamento de Biologia Experimental, Faculdade de Medicina, Universidade do Porto Porto, Portugal
    Front Syst Neurosci 6:5. 2012
    ..Overall, these findings demonstrate that, even in the absence of peripheral taste input, IC regulates food choices based on postingestive signals...
  5. pmc Sweet taste signaling and the formation of memories of energy sources
    Ivan E de Araujo
    The John B Pierce Laboratory, Department of Psychiatry, Yale University School of Medicine New Haven, CT, USA
    Front Syst Neurosci 5:99. 2011
    ..From a mechanistic viewpoint, current evidence favors the concept that gastrointestinal and post-absorptive signals contribute in parallel to sweet-independent sugar acceptance and dopamine release...
  6. pmc Sweet taste signaling functions as a hypothalamic glucose sensor
    Xueying Ren
    The John B Pierce Laboratory New Haven, CT, USA
    Front Integr Neurosci 3:12. 2009
    ..Taken together, our findings suggest that the heterodimeric G-protein coupled sweet receptor T1R2/T1R3 is a candidate membrane-bound brain glucosensor...
  7. pmc Glucose utilization rates regulate intake levels of artificial sweeteners
    Luis A Tellez
    I E de Araujo The John B Pierce Laboratory and Yale University School of Medicine, 290 Congress Avenue, New Haven, CT 06519, USA or
    J Physiol 591:5727-44. 2013
    ....
  8. pmc Metabolic regulation of brain response to food cues
    Ivan E de Araujo
    The John B Pierce Laboratory, New Haven, CT 06519, USA
    Curr Biol 23:878-83. 2013
    ..We conclude that glucose metabolism is a critical signal regulating NAcc and hypothalamic response to food cues, and that this process operates independently from the ability of calories to condition liking...
  9. pmc The gut-brain dopamine axis: a regulatory system for caloric intake
    Ivan E de Araujo
    The John B Pierce Laboratory, New Haven, CT 06519, USA
    Physiol Behav 106:394-9. 2012
    ....
  10. pmc The gustatory cortex and multisensory integration
    I E de Araujo
    The John B Pierce Laboratory and Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06519, USA
    Int J Obes (Lond) 33:S34-43. 2009
    ..Therefore, rather than working as the receptive field of peripheral taste receptor cells, the central gustatory pathways seem to operate as a multisensory system dedicated to evaluating the biological significance of intra-oral stimuli...
  11. ncbi request reprint Gustatory and homeostatic functions of the rodent parabrachial nucleus
    Ivan E de Araujo
    Department of Psychiatry, The John B Pierce Laboratory, Yale University School of Medicine, New Haven, Connecticut, USA
    Ann N Y Acad Sci 1170:383-91. 2009
    ....
  12. ncbi request reprint Nutrient selection in the absence of taste receptor signaling
    Xueying Ren
    The John B Pierce Laboratory, New Haven, Connecticut 06519, USA
    J Neurosci 30:8012-23. 2010
    ....
  13. ncbi request reprint A gut lipid messenger links excess dietary fat to dopamine deficiency
    Luis A Tellez
    The John B Pierce Laboratory, New Haven, CT 06519, USA
    Science 341:800-2. 2013
    ..Our findings suggest that high-fat-induced gastrointestinal dysfunctions play a key role in dopamine deficiency and that restoring gut-generated lipid signaling may increase the reward value of less palatable, yet healthier, foods. ..
  14. ncbi request reprint Neural ensemble coding of satiety states
    Ivan E de Araujo
    Department of Neurobiology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Neuron 51:483-94. 2006
    ..This distributed population code might constitute a neural mechanism underlying meal initiation under different metabolic states...
  15. pmc Regulation of fat intake in the absence of flavour signalling
    Jozélia G Ferreira
    The John B Pierce Laboratory, New Haven, CT 06519, USA
    J Physiol 590:953-72. 2012
    ....
  16. pmc Flavor-independent maintenance, extinction, and reinstatement of fat self-administration in mice
    Luis A Tellez
    John B Pierce Laboratory, New Haven, Connecticut Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, USA
    Biol Psychiatry 73:851-9. 2013
    ....
  17. ncbi request reprint Effects of ad libitum ingestion of monosodium glutamate on weight gain in C57BL6/J mice
    Xueying Ren
    The John B Pierce Laboratory, Yale University School of Medicine, New Haven, CT 06519, USA
    Digestion 83:32-6. 2011
    ..In summary, our data does not support the notion that ad libitum MSG intake should trigger the development of obesity or other metabolic abnormalities...
  18. ncbi request reprint The neural mechanisms of gustation: a distributed processing code
    Sidney A Simon
    Department of Neurobiology, Duke University, Durham, North Carolina 27710, USA
    Nat Rev Neurosci 7:890-901. 2006
    ..On the basis of recent experimental data, we argue that these brain circuits make use of distributed ensemble codes that represent the sensory and post-ingestive properties of tastants...
  19. ncbi request reprint The neural signature of satiation is associated with ghrelin response and triglyceride metabolism
    Xue Sun
    Yale Interdepartmental Neuroscience Program, Yale Medical School, New Haven, CT, USA John B Pierce Laboratory, 290 Congress Avenue, New Haven, CT, USA Electronic address
    Physiol Behav 136:63-73. 2014
    ..We conclude that satiation-induced changes in brain response to a palatable food are strongly and specifically associated with changes in circulating ghrelin and triglycerides and by volitional meal termination. ..
  20. pmc Enantiomer-specific selection of amino acids
    Xueying Ren
    The John B Pierce Laboratory, 290 Congress Avenue, New Haven, CT, 06519, USA
    Amino Acids 45:1353-64. 2013
    ..We conclude that the ability to promote increases in respiratory exchange ratios enhances the reward value of nutritionally relevant amino acids and suggest a mechanistic link between substrate utilization and amino acid preferences...
  21. pmc The salty and burning taste of capsaicin
    Sidney A Simon
    Department of Neurobiology and Center of Neuroengineering, Duke University Medical Center, Durham, NC 27710, USA
    J Gen Physiol 125:531-4. 2005