Research Topics
| Joseph F DastaSummaryAffiliation: The Ohio State University Country: USA Publications
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Detail Information
Publications
Critical care therapeutics: a frontier for clinical pharmacy. 1982Joseph F Dasta
College of Pharmacy, and Assistant Professor, Department of Anesthesiology, College of Medicine, The Ohio State University, 500 W. 12th Ave, Columbus, OH 43210, USA
Ann Pharmacother 40:740-1. 2006- Amphotericin B lipid complex for Hansenula anomala pneumoniaSandra L Kane
College of Pharmacy, Ohio State University, 500 W 12th Ave, Columbus, OH 43210, USA
Ann Pharmacother 36:59-62. 2002..To document the first successful treatment of a patient with Hansenula anomala pneumonia... - Critical careJoseph F Dasta
College of Pharmacy, The Ohio State University, 500 W 12th Ave, Columbus, OH 43210 1291, USA
Ann Pharmacother 40:736-7. 2006.... - Impact of drotrecogin alfa (activated) on resource use and implications for reimbursementJoseph F Dasta
College of Pharmacy, The Ohio State University, Columbus, Ohio 43210, USA
Pharmacotherapy 22:216S-222S. 2002..Clinicians and administrators should work collaboratively to optimize the therapy of patients with severe sepsis, minimize the financial impact on the health care system, and maximize the utility of drotrecogin alfa (activated)... - Comparing dexmedetomidine prescribing patterns and safety in the naturalistic setting versus published dataJoseph F Dasta
College of Pharmacy, The Ohio State University, Columbus, OH 43210 1291, USA
Ann Pharmacother 38:1130-5. 2004..In clinical practice, new drugs may be used differently than the product labeling recommends. Furthermore, it often takes several years of use before adverse drug reactions (ADRs) are reported... 
A cost-minimization analysis of dexmedetomidine compared with midazolam for long-term sedation in the intensive care unitJoseph F Dasta
Ohio State University, USA
Crit Care Med 38:497-503. 2010..To compare the intensive care unit costs and determine factors influencing these costs in mechanically ventilated patients randomized to dexmedetomidine or midazolam by continuous infusion...- Update on tolvaptan for the treatment of hyponatremiaJoseph F Dasta
College of Pharmacy, The Ohio State University, Columbus, USA
Expert Rev Pharmacoecon Outcomes Res 12:399-410. 2012.... - A new dosing protocol reduces dexmedetomidine-associated hypotension in critically ill surgical patientsAnthony T Gerlach
Department of Pharmacy, The Ohio State University Medical Center, Columbus, Ohio 43210, USA
J Crit Care 24:568-74. 2009..We evaluated occurrence of hypotension and bradycardia in critically ill surgical patients receiving dexmedetomidine before and after implementation of a dosing protocol... - Costs and outcomes of acute kidney injury (AKI) following cardiac surgeryJoseph F Dasta
College of Pharmacy, The Ohio State University, Columbus, OH 43210, USA
Nephrol Dial Transplant 23:1970-4. 2008..We determined costs, resource use and mortality rate of patients. We used the serum creatinine component of the RIFLE system to classify AKI... - International critical care hospital pharmacist activitiesJaclyn M LeBlanc
College of Pharmacy, The Ohio State University, 500 West 12th Ave, Columbus, OH 43210, USA
Intensive Care Med 34:538-42. 2008..The objective of this study was to describe the duties and activities of international pharmacists who practice in critical care... - An updated focused review of dexmedetomidine in adultsAnthony T Gerlach
Ohio State University Medical Center and Ohio State University, Columbus, OH, USA
Ann Pharmacother 43:2064-74. 2009..To evaluate recent comparative studies regarding the safety and efficacy of dexmedetomidine in adults... - Pharmacoeconomics of sedation in the ICUJoseph F Dasta
The Ohio State University, College of Pharmacy, Columbus, OH, USA
Crit Care Clin 25:571-83, ix. 2009..Clinicians should look beyond the acquisition cost of a sedative and include the effect of sedatives on the cost of care when selecting the most appropriate sedative... - Acute renal failure in hospitalized patients: part IMaria C Pruchnicki
Division of Pharmacy Practice and Administration, College of Pharmacy, The Ohio State University, Columbus, OH 43210 1291, USA
Ann Pharmacother 36:1261-7. 2002..Acute renal failure (ARF) is a common condition in hospitalized patients. Morbidity, mortality, and health resource use are considerable, but the true magnitude of the problem is not well described in the literature... - Acute renal failure in hospitalized patients: part IIMaria C Pruchnicki
Division of Pharmacy Practice and Administration, College of Pharmacy, The Ohio State University, Columbus, OH 43210 1291, USA
Ann Pharmacother 36:1430-42. 2002..Acute renal failure (ARF) is a common condition in hospitalized patients. Research has been unable to identify the optimal target for therapeutic intervention; hence, effective prevention of and/or treatment for ARF remain elusive... - Role of the bispectral index in sedation monitoring in the ICUJaclyn M LeBlanc
College of Pharmacy, The Ohio State University, Columbus, 43210, USA
Ann Pharmacother 40:490-500. 2006..We recommend that further studies be conducted to determine the optimal method of obtaining BIS data and evaluate the impact of the BIS on relevant patient outcomes... - Survey of hospital pharmacist activities outside of the United StatesJaclyn M LeBlanc
College of Pharmacy, University of Oklahoma, Tulsa, OK 74135, USA
Am J Health Syst Pharm 64:1748-55. 2007 - Dexmedetomidine: an updated reviewAnthony T Gerlach
The Ohio State University Medical Center, The Ohio State University, Columbus, OH, USA
Ann Pharmacother 41:245-52. 2007..To review recent literature on the safety and efficacy of dexmedetomidine... - Evaluation of costs associated with tolvaptan-mediated hospital length of stay reduction among US patients with the syndrome of inappropriate antidiuretic hormone secretion, based on SALT-1 and SALT-2 trialsJoseph F Dasta
Professor Emeritus, College of Pharmacy, The Ohio State University, Columbus, OH 43210, USA
Hosp Pract (1995) 40:7-14. 2012.... - Addition of dexmedetomidine to standard sedation regimens after cardiac surgery: an outcomes analysisJoseph F Dasta
College of Pharmacy, The Ohio State University, Columbus, Ohio 43210-1291, and the Department of Pharmacy, Clarian Health, Indianapolis, IN, USA
Pharmacotherapy 26:798-805. 2006.... 
An instructional seminar for online case-based discussionsJaclyn M LeBlanc
College of Pharmacy, The Ohio State University, USA
Am J Pharm Educ 71:42. 2007..To assess a training seminar developed to prepare pharmacy instructors to facilitate online discussions...- Pharmacoeconomics of sedation in the ICUJoseph F Dasta
The Ohio State University, College of Pharmacy, Columbus, OH, USA University of Texas, College of Pharmacy, Austin, TX, USA PO Box 967, Hutto, TX 78634 0967, USA
Anesthesiol Clin 29:707-20. 2011..Clinicians should look beyond the acquisition cost of a sedative and include the effect of sedatives on the cost of care when selecting the most appropriate sedative... - Impact of disease states on the pharmacokinetics and pharmacodynamics of angiotensin-converting enzyme inhibitorsJaclyn M LeBlanc
College of Pharmacy, The Ohio State University, Columbus, Ohio, USA
J Clin Pharmacol 46:968-80. 2006..ACE inhibitor dosing for hypertension is reasonable based on pharmacokinetics and EC50 values. Further individualization of therapy may improve outcomes, and using the threshold AUC/EC50 ratio may help guide appropriate dosing... - Intravenous to oral conversion of antihypertensives: a toolkit for guideline developmentJoseph F Dasta
The Ohio State University, Columbus, OH, USA
Ann Pharmacother 44:1430-47. 2010..To provide a toolkit of information for hospitals to use in developing intravenous to oral conversion protocols for antihypertensives... - Scope of international hospital pharmacy practiceJaclyn M LeBlanc
College of Pharmacy, The Ohio State University, Columbus, OH 43210-1291, USA
Ann Pharmacother 39:183-91. 2005.... - Daily cost of an intensive care unit day: the contribution of mechanical ventilationJoseph F Dasta
The Ohio State University, Columbus, OH, USA
Crit Care Med 33:1266-71. 2005..Interventions that result in reduced intensive care unit length of stay and/or duration of mechanical ventilation could lead to substantial reductions in total inpatient cost... - Clinical outcomes of critical illness polyneuropathySandra L Kane
School of Pharmacy, University of Pittsburgh, Pennsylvania 15261, USA
Pharmacotherapy 22:373-9. 2002..The association of CIP with sepsis, multiorgan failure, and drugs is still unclear... - Characteristics, drug therapy, and outcomes from a database of 500,000 hospitalized patients with a discharge diagnosis of heart failureTien M H Ng
University of Southern California, School of Pharmacy, Los Angeles, CA 90033, USA
Congest Heart Fail 14:202-10. 2008..HF commonly exists in hospitalized patients and is associated with significant morbidity, mortality, and economic burden, irrespective of whether it is the primary diagnosis or a secondary comorbidity... - Propofol associated with a shorter duration of mechanical ventilation than scheduled intermittent lorazepam: a database analysis using Project IMPACTJeffrey J Fong
School of Pharmacy, Northeastern University, Boston, MA 02115, USA
Ann Pharmacother 41:1986-91. 2007.... - Bispectral index does not correlate with the stress response in critical care patientsJaclyn M LeBlanc
Anesth Analg 104:1616. 2007 - Contemporary issues in the pharmacologic management of acute heart failureTien M H Ng
Department of Pharmacy, University of Southern California, 1985 Zonal Avenue, Los Angeles, CA 90033, USA
Crit Care Clin 22:199-219, v. 2006..Clinicians should understand the rationale for use and limitations of each therapy to maximize benefit and cost-effectiveness, while minimizing the potential for adverse outcomes... - Critical care pharmacy services in United States hospitalsRobert MacLaren
Department of Clinical Pharmacy, School of Pharmacy, University of Colorado Health Sciences Center, Denver, CO 80262, USA
Ann Pharmacother 40:612-8. 2006..Critical care pharmacy activities have been described as fundamental, desirable, and optimal, but actual services provided have not been evaluated... - Practice parameters for hemodynamic support of sepsis in adult patients: 2004 updateSteven M Hollenberg
Crit Care Med 32:1928-48. 2004..Using this approach, specific recommendations for fluid resuscitation, vasopressor therapy, and inotropic therapy of septic in adult patients were promulgated... - Intensive insulin therapy for critically ill patientsKelly S Lewis
Associate Professor of Anesthesiology, Division of Critical Care, Rush Presbyterian St Luke's Medical Center, Chicago, IL, USA
Ann Pharmacother 38:1243-51. 2004..Frequent monitoring is imperative to avoid hypoglycemia... - Impact of intensive care unit (ICU) drug use on hospital costs: a descriptive analysis, with recommendations for optimizing ICU pharmacotherapyRobert J Weber
Department of Pharmacy and Therapeutics, University of Pittsburgh School of Pharmacy, Pittsburgh, PA 15213, USA
Crit Care Med 31:S17-24. 2003..CONCLUSIONS: ICU drug therapies have a significant impact on hospital costs, and effective clinical informatics services and multidisciplinary collaboration programs are necessary to optimize ICU pharmacotherapy... - Managing anemia in the critically ill patientMaria I Rudis
Department of Pharmacy, School of Pharmacy, University of Southern California, Los Angeles, California 90033, USA
Pharmacotherapy 24:229-47. 2004..Patient selection for erythropoietic agents will depend on further work dealing with outcomes and the total cost of care in managing the anemia of critical illness... - The impact of critical care pharmacists on enhancing patient outcomesSandra L Kane
School of Pharmacy, University of Pittsburgh, 3501 Terrace Street, Pittsburgh, PA 15261, USA
Intensive Care Med 29:691-8. 2003..Furthermore, economic evaluations of clinical pharmacy services in the ICU consistently reveal the potential for considerable cost savings...