G A Cox

Summary

Affiliation: The Jackson Laboratory
Country: USA

Publications

  1. ncbi request reprint PCR analysis of muscular dystrophy in mdx mice
    J S Chamberlain
    Department of Human Genetics, University of Michigan Medical School, Ann Arbor 48109 0618
    Mol Cell Biol Hum Dis Ser 3:167-89. 1993
  2. ncbi request reprint Identification of the mouse neuromuscular degeneration gene and mapping of a second site suppressor allele
    G A Cox
    The Jackson Laboratory, Bar Harbor, Maine 04609, USA
    Neuron 21:1327-37. 1998
  3. ncbi request reprint The mouse fidgetin gene defines a new role for AAA family proteins in mammalian development
    G A Cox
    The Jackson Laboratory, Bar Harbor, Maine, USA
    Nat Genet 26:198-202. 2000
  4. ncbi request reprint Spontaneous mutations in the mouse Sharpin gene result in multiorgan inflammation, immune system dysregulation and dermatitis
    R E Seymour
    The Jackson Laboratory, Bar Harbor, ME 04609, USA
    Genes Immun 8:416-21. 2007
  5. ncbi request reprint Sodium/hydrogen exchanger gene defect in slow-wave epilepsy mutant mice
    G A Cox
    The Jackson Laboratory, Bar Harbor, Maine 04609, USA
    Cell 91:139-48. 1997
  6. ncbi request reprint Expression of terminal differentiation proteins defines stages of mouse mammary gland development
    I Mikaelian
    Igor Mikaelian, Box 98, The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609 1500, USA
    Vet Pathol 43:36-49. 2006
  7. pmc Forced expression of dystrophin deletion constructs reveals structure-function correlations
    J A Rafael
    Department of Human Genetics, University of Michigan Medical School, Ann Arbor, 48109, USA
    J Cell Biol 134:93-102. 1996
  8. ncbi request reprint Characterization of dystrophin and utrophin diversity in the mouse
    C N Lumeng
    Department of Human Genetics, University of Michigan Medical School, 1150 West Medical Center Drive, Ann Arbor, MI 48109 0618, USA
    Hum Mol Genet 8:593-9. 1999
  9. ncbi request reprint Dp71 can restore the dystrophin-associated glycoprotein complex in muscle but fails to prevent dystrophy
    G A Cox
    Department of Human Genetics, University of Michigan Medical School, Ann Arbor 48109 0618
    Nat Genet 8:333-9. 1994
  10. ncbi request reprint Overexpression of dystrophin in transgenic mdx mice eliminates dystrophic symptoms without toxicity
    G A Cox
    Department of Human Genetics, University of Michigan Medical School, Ann Arbor 48109 0618
    Nature 364:725-9. 1993

Collaborators

Detail Information

Publications12

  1. ncbi request reprint PCR analysis of muscular dystrophy in mdx mice
    J S Chamberlain
    Department of Human Genetics, University of Michigan Medical School, Ann Arbor 48109 0618
    Mol Cell Biol Hum Dis Ser 3:167-89. 1993
    ..It is hoped that such analyses will further attempts to determine the feasibility of using gene therapy as a treatment for DMD/BMD...
  2. ncbi request reprint Identification of the mouse neuromuscular degeneration gene and mapping of a second site suppressor allele
    G A Cox
    The Jackson Laboratory, Bar Harbor, Maine 04609, USA
    Neuron 21:1327-37. 1998
    ..The identification of the nmd gene and mapping of a major suppressor provide new opportunities for understanding mechanisms of motor neuron degeneration...
  3. ncbi request reprint The mouse fidgetin gene defines a new role for AAA family proteins in mammalian development
    G A Cox
    The Jackson Laboratory, Bar Harbor, Maine, USA
    Nat Genet 26:198-202. 2000
    ..Fidgetin is the first mutant AAA protein found in a mammalian developmental mutant, thus defining a new role for these proteins in embryonic development...
  4. ncbi request reprint Spontaneous mutations in the mouse Sharpin gene result in multiorgan inflammation, immune system dysregulation and dermatitis
    R E Seymour
    The Jackson Laboratory, Bar Harbor, ME 04609, USA
    Genes Immun 8:416-21. 2007
    ..These are the first examples of disease-causing mutations in the Sharpin gene and demonstrate the importance of SHARPIN protein in normal immune development and control of inflammation...
  5. ncbi request reprint Sodium/hydrogen exchanger gene defect in slow-wave epilepsy mutant mice
    G A Cox
    The Jackson Laboratory, Bar Harbor, Maine 04609, USA
    Cell 91:139-48. 1997
    ..This first example of a disease-causing mutation in an Nhe gene provides a new tool for studying the delicate balance of neuroexcitability and cell survival within the CNS...
  6. ncbi request reprint Expression of terminal differentiation proteins defines stages of mouse mammary gland development
    I Mikaelian
    Igor Mikaelian, Box 98, The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609 1500, USA
    Vet Pathol 43:36-49. 2006
    ..Finally, consistent with results of earlier studies, keratins 1, 10, 13, and 15, and filaggrin, involucrin, and loricrin were not detected at any stage of mammary gland development...
  7. pmc Forced expression of dystrophin deletion constructs reveals structure-function correlations
    J A Rafael
    Department of Human Genetics, University of Michigan Medical School, Ann Arbor, 48109, USA
    J Cell Biol 134:93-102. 1996
    ..However, the remainder of the COOH terminus is not required for assembly of the DAP complex...
  8. ncbi request reprint Characterization of dystrophin and utrophin diversity in the mouse
    C N Lumeng
    Department of Human Genetics, University of Michigan Medical School, 1150 West Medical Center Drive, Ann Arbor, MI 48109 0618, USA
    Hum Mol Genet 8:593-9. 1999
    ..Our results provide further evidence for a common evolutionary origin of the utrophin and dystrophin genes...
  9. ncbi request reprint Dp71 can restore the dystrophin-associated glycoprotein complex in muscle but fails to prevent dystrophy
    G A Cox
    Department of Human Genetics, University of Michigan Medical School, Ann Arbor 48109 0618
    Nat Genet 8:333-9. 1994
    ....
  10. ncbi request reprint Overexpression of dystrophin in transgenic mdx mice eliminates dystrophic symptoms without toxicity
    G A Cox
    Department of Human Genetics, University of Michigan Medical School, Ann Arbor 48109 0618
    Nature 364:725-9. 1993
    ..Our results provide functional evidence for the feasibility of gene therapy for DMD...
  11. ncbi request reprint New mdx mutation disrupts expression of muscle and nonmuscle isoforms of dystrophin
    G A Cox
    Department of Human Genetics, University of Michigan Medical School, Ann Arbor 48109 0618
    Nat Genet 4:87-93. 1993
    ..This new mdx mutant will provide an improved model system for functional studies of the dystrophin C-terminus in muscle and nonmuscle tissues...
  12. ncbi request reprint Urachal sinus presenting as periumbilical dermatitis
    G A Cox
    Br J Dermatol 157:419-20. 2007