Research Topics
| Fernando G CosioSummaryAffiliation: The Ohio State University Country: USA Publications
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Detail Information
Publications
Patient survival after renal transplantation III: the effects of statinsFernando G Cosio
Department of Internal Medicine, and Center for Biostatistics, The Ohio State University, Columbus, OH 43210 1250, USA
Am J Kidney Dis 40:638-43. 2002..Although the use of HMG-CoA reductase inhibitors (statins) is associated with improved survival in the general population, the effects of these drugs on the survival of kidney transplant recipients have not been established...- Patient survival after renal transplantation: IV. Impact of post-transplant diabetesFernando G Cosio
Department of Internal Medicine, The Ohio State University Medical Center, 1654 Upham Drive, Columbus, OH 43210 1250 USA
Kidney Int 62:1440-6. 2002..This study examined the cardiovascular risk profile of patients with post-transplant diabetes (PTDM) and assessed the impact of PTDM on patient survival... - Predicting subsequent decline in kidney allograft function from early surveillance biopsiesFernando G Cosio
Department of Internal Medicine, Division of Nephrology and Hypertension, Mayo Clinic and Foundation, Rochester, Minnnesota, USA
Am J Transplant 5:2464-72. 2005..In conclusion, inflammation and glomerulopathy 1 year post-transplant predict loss of graft function and graft failure independently of function and other variables... 
Significance and implications of capillaritis during acute rejection of kidney allograftsFernando G Cosio
Department of Internal Medicine, Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN, USA
Transplantation 89:1088-94. 2010..CONCLUSIONS.: DSA-I increases the risk of C4d-AR. The presence of DSA-I or II is associated with capillaritis during AR. Capillaritis is associated with reduced graft survival...- Recurrent membranoproliferative glomerulonephritis after kidney transplantationElizabeth C Lorenz
Division of Nephrology and Hypertension, Department of Internal Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota, USA
Kidney Int 77:721-8. 2010..Our study shows the risk of MPGN recurrence and progression depends on identifiable pretransplant characteristics, has variable clinical impact, and can result in graft failure... - The relationship between donor age and cadaveric renal allograft survival is modified by the recipient's blood pressureFernando G Cosio
Departments of Internal Medicine, Pathology, Surgery and Center for Biostatistics, The Ohio State University, Columbus, Ohio, USA
Am J Transplant 3:340-7. 2003..These data suggest that poorly functioning kidneys have reduced survival irrespective of age. Furthermore, elevated BP levels may have a particularly negative effect on the survival of older grafts... - Antibody-mediated rejection following transplantation from an HLA-identical siblingCarrie A Grafft
Division of Nephrology and Hypertension, Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA
Nephrol Dial Transplant 25:307-10. 2010..A biopsy for allograft dysfunction suggested AMR, but DSA could not be detected. Treatment for rejection was transiently successful. Undetectable minor histocompatibility antibodies may have contributed... - Kidney allograft fibrosis and atrophy early after living donor transplantationFernando G Cosio
Department of Internal Medicine, Division of Nephrology and Hypertension, Mayo Clinic and Foundation, Rochester, Minnesota, USA
Am J Transplant 5:1130-6. 2005..GIF frequently develops in the absence of risk factors. Lower GFR post-transplant identify patients at highest risk of GIF... - Living donor kidney and autologous stem cell transplantation for primary systemic amyloidosis (AL) with predominant renal involvementNelson Leung
Department of Internal Medicine, Division of Nephrology and Hypertension, Mayo Clinic and Foundation, Rochester, MN, USA
Am J Transplant 5:1660-70. 2005..This experience supports the feasibility of sequential living donor KTx and autologous SCT for carefully selected patients with ESRD due to AL... - Comparison of low versus high tacrolimus levels in kidney transplantation: assessment of efficacy by protocol biopsiesFernando G Cosio
Department of Internal Medicine, Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN, USA
Transplantation 83:411-6. 2007..The use of calcineurin inhibitors is generally guided by drug blood levels. However, those levels are chosen based on clinical experience, lacking adequate titration studies... - Transplant glomerulopathy: risk and prognosis related to anti-human leukocyte antigen class II antibody levelsNaim Issa
Division of Nephrology and Hypertension and Transplant Center, Department of Internal Medicine, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
Transplantation 86:681-5. 2008..The goal of this study was to determine the relationships among antibody characteristics (level and specificity), risk for TG, and graft survival... - Long-term follow-up of patients with monoclonal gammopathy of undetermined significance after kidney transplantationHarris V K Naina
Department of Internal Medicine, Division of Hematology and Oncology, University of Texas Southwestern, Dallas, Tex, USA
Am J Nephrol 35:365-71. 2012..We evaluated the long-term outcomes of these patients in a single-center retrospective study from the Mayo Clinic, Rochester, Minn., USA... - New onset hyperglycemia and diabetes are associated with increased cardiovascular risk after kidney transplantationFernando G Cosio
Division of Nephrology and Hypertension, Department of Internal Medicine, Mayo Clinic and Foundation, Rochester, Minnesota 55905, USA
Kidney Int 67:2415-21. 2005..Post-transplant diabetes (PTDM) is a common and serious complication of kidney transplantation. The implications of developing hyperglycemia of lesser severity are not well understood... - Pulmonary hypertension is associated with reduced patient survival after kidney transplantationNaim Issa
Division of Nephrology and Hypertension, Department of Internal Medicine, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
Transplantation 86:1384-8. 2008..Pulmonary hypertension (PH) is common in patients on dialysis where it is associated with reduced survival. The possible association between PH and kidney transplant recipient survival has not been previously evaluated... - Patient and graft outcomes from older living kidney donors are similar to those from younger donors despite lower GFRLourdes S Peña de la Vega
Division of Nephrology and Hypertension, Department of Internal Medicine, Mayo Clinic and Foundation, Rochester, Minnesota 55905, USA
Kidney Int 66:1654-61. 2004..Donor age adversely affects deceased-donor kidney transplant outcomes, but its influence on living-donor transplantation is less well characterized... - Bleeding complications after transcutaneous kidney biopsy in patients with systemic amyloidosis: single-center experience in 101 patientsSandra M Soares
Department of Internal Medicine, Mayo Clinic Rochester, Rochester, MN 55902, USA
Am J Kidney Dis 52:1079-83. 2008..Amyloidosis is thought to be 1 of the risk factors, but this has not been confirmed in a large study. We performed this study to assess the risk of bleeding after kidney biopsy in patients with amyloidosis... - The impact of urinary tract infections in renal transplant recipientsElizabeth C Lorenz
Division of Nephrology and Hypertension, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA
Kidney Int 78:719-21. 2010..Many risk factors contribute to the high incidence of UTIs, which can undermine graft function and survival. Given that many UTIs are asymptomatic, screening protocols may be beneficial... - EBV kidney allograft infection: possible relationship with a peri-graft localization of PTLDFernando G Cosio
Internal Medicine Pathology Surgery, The Ohio State University, Columbus, Ohio, USA
Am J Transplant 4:116-23. 2004..It is concluded that EBV can infect kidney allografts, and there appears to be a relationship between this infection and the presence of PTLD near the graft... - Obesity in living kidney donors: clinical characteristics and outcomes in the era of laparoscopic donor nephrectomyJulie K Heimbach
Mayo Clinic College of Medicine, Department of Transplant Surgery, Rochester, Minnesota, USA
Am J Transplant 5:1057-64. 2005..While early results are encouraging, we advocate careful study of obese donors and do not support their widespread use until longer follow-up is available... - Diurnal blood pressure changes one year after kidney transplantation: relationship to allograft function, histology, and resistive indexHani M Wadei
Department of Medicine, Division of Nephrology and Hypertension, Mayo Clinic College of Medicine, Rochester, Minnesota, USA
J Am Soc Nephrol 18:1607-15. 2007..Further studies are needed to determine whether restoration of normal BP pattern will confer better allograft outcome... - Cardiovascular disease after transplantation: do we know all of the variables?Fernando G Cosio
Am J Transplant 3:915-6. 2003 - Measured and estimated GFR in healthy potential kidney donorsAndrew D Rule
Division of Nephrology and Internal Medicine, Mayo Clinic, Rochester, MN 55905, USA
Am J Kidney Dis 43:112-9. 2004..In healthy individuals, GFR cannot be estimated accurately using the abbreviated MDRD or Cockcroft-Gault prediction equations... 
Sirolimus reduces polycystic liver volume in ADPKD patientsQi Qian
Division of Nephrology and Hypertension, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA
J Am Soc Nephrol 19:631-8. 2008..In summary, treatment with sirolimus was associated with decreased polycystic liver volume, perhaps by preventing aberrant activation of mTOR in epithelial cells lining the cysts...- Transplantation in the diabetic patient with advanced chronic kidney disease: a task force reportRobert S Gaston
Division of Nephrology, University of Alabama at Birmingham, Birmingham, AL 35294, USA
Am J Kidney Dis 44:529-42. 2004..This report summarizes the deliberations and recommendations of the task force... - Kidney transplant histology after one year of continuous therapy with sirolimus compared with tacrolimusPatrick G Dean
1 Department of Surgery, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
Transplantation 85:1212-5. 2008..This potential benefit is offset by lower success rate in maintaining the regimen and was not accompanied by superior glomerular filtration rate at 1 year... - Delayed-onset primary cytomegalovirus disease and the risk of allograft failure and mortality after kidney transplantationSupha K Arthurs
Divisions of Infectious Diseases, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
Clin Infect Dis 46:840-6. 2008..We evaluated the incidence, clinical features, risk factors, and outcomes of CMV disease among high-risk kidney transplant recipients... - Limitations of estimating glomerular filtration rate from serum creatinine in the general populationAndrew D Rule
Division of Epidemiology, Mayo Clinic College of Medicine, 200 First St SW, Rochester, MN 55905, USA
Mayo Clin Proc 81:1427-34. 2006..To compare estimated glomerular filtration rate (GFR) in the general population on the basis of equations derived from different subsets of the general population...