Research Topics
| M S CohenSummaryAffiliation: The Children's Hospital of Philadelphia Country: USA Publications
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Detail Information
Publications
Clinical practice: the effect of obesity in children with congenital heart diseaseMeryl S Cohen
Division of Cardiology, Department of Pediatrics at the Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
Eur J Pediatr 171:1145-50. 2012..Recommendations for safe physical activity, recreation sport, and exercise training for children with CHD have recently been published. These guidelines may help health care providers to change their practice of exercise restriction...
Fetal diagnosis and management of congenital heart diseaseM S Cohen
Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia, USA
Clin Perinatol 28:11-29, v-vi. 2001..Fetal diagnosis remains an integral part of the management of children with cardiac lesions...
Echocardiographic imaging of anomalous origin of the coronary arteriesMeryl S Cohen
Division of Cardiology, The Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, United States of America
Cardiol Young 20:26-34. 2010....
Mentorship, learning curves, and balanceMeryl S Cohen
The Cardiac Center at The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, United States of America
Cardiol Young 17:164-74. 2007..The concepts of mentorship, learning curves and balance cannot be underappreciated...
Controversies, genetics, diagnostic assessment, and outcomes relating to the heterotaxy syndromeMeryl S Cohen
Division of Cardiology, The Cardiac Center at The Children s Hospital of Philadelphia and the University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, United States of America
Cardiol Young 17:29-43. 2007..Attention is given to the various diagnostic modalities, including fetal and postnatal echocardiography, recent tomographic and magnetic resonance imaging techniques, and the time-honoured approach using angiography...
Is the arterial switch operation as good over the long term as we thought it would be?Meryl S Cohen
Division of Cardiology, The Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
Cardiol Young 16:117-24. 2006
Heterotaxy syndrome with functional single ventricle: does prenatal diagnosis improve survival?Meryl S Cohen
Division of Cardiology, The Cardiac Center at The Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
Ann Thorac Surg 82:1629-36. 2006..Prenatal identification of heterotaxy syndrome may improve long-term survival...
Does fetal diagnosis make a difference?Meryl S Cohen
Division of Cardiology, The Children s Hospital of Philadelphia, 34th Street and Civic Center Boulevard, Philadelphia, PA 19104, USA
Clin Perinatol 32:877-90, viii. 2005..We hope that the recognition of critical congenital heart disease in utero improves the long-term outcome of our patients, including neurodevelopmental outcome and quality of life...
Fetal and childhood onset of adult cardiovascular diseasesMeryl S Cohen
Division of Cardiology, Department of Pediatrics, University of Pennsylvania School of Medicine, 34th and Civic Center Boulevard, Philadelphia, PA 19104, USA
Pediatr Clin North Am 51:1697-719, x. 2004..Better understanding of the etiology of these disease states will bring with it enhanced preventive and targeted therapies...
Deviation of atrial septum primum in association with normal left atrioventricular valve sizeM S Cohen
Cardiac Center at The Children s Hospital of Philadelphia, PA, USA
J Am Soc Echocardiogr 14:732-7. 2001..Superoposterior DASP carries less physiologic consequence. Echocardiography can distinguish this anomaly from other forms of left atrial obstruction...
Neo-aortic root dilation and valve regurgitation up to 21 years after staged reconstruction for hypoplastic left heart syndromeMeryl S Cohen
Department of Pediatrics, University of Pennsylvania School of Medicine, Cardiac Center at Children s Hospital of Philadelphia, 19104, USA
J Am Coll Cardiol 42:533-40. 2003..We sought to assess the prevalence and progression of neo-aortic root dilation and valvar regurgitation after staged reconstruction for hypoplastic left heart syndrome (HLHS)...
Diagnostic assessment before Fontan operation in patients with bidirectional cavopulmonary anastomosis: are noninvasive methods sufficient?Pamela S Ro
Division of Cardiology, The Children s Hospital of Philadelphia, Pennsylvania 19104, USA
J Am Coll Cardiol 44:184-7. 2004..This study was designed to determine if a subset of patients who have undergone bidirectional cavopulmonary anastomosis could be identified in which catheterization was of little benefit before completion of the Fontan procedure...
Functional state of patients with heterotaxy syndrome following the Fontan operationAndrew M Atz
Department of Pediatrics, Division of Cardiology, Medical University of South Carolina, Children s Hospital, Charleston, South Carolina 29425, United States of America
Cardiol Young 17:44-53. 2007..Little is known, however, about the functional state of surviving patients with heterotaxy following a Fontan operation...
Following the arterial switch operation, obese children have risk factors for early cardiovascular diseaseSara K Pasquali
Division of Cardiology, Department of Pediatrics, The Children s Hospital of Philadelphia, Philadelphia, PA, USA
Congenit Heart Dis 5:16-24. 2010..Obesity may also pose cardiovascular risk. The purpose of this study was to evaluate comorbidities and markers of early cardiovascular disease in obese ASO patients...
Guidelines for the outpatient management of complex congenital heart diseaseGil Wernovsky
Division of Pediatric Cardiology, The Children s Hospital of Philadelphia, Philadelphia, PA, USA
Congenit Heart Dis 1:10-26. 2006..The purpose of this position article is to provide a framework for outpatient follow-up of complex congenital heart disease, based on a review of current literature and the experience of the authors...
Heterotaxy syndrome with mirror image anomalies in identical twinsDeepika Thacker
Pediatric Cardiology, Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
Congenit Heart Dis 4:50-3. 2009..We report a case of monozygotic twins, both with heterotaxy syndrome, complex congenital heart disease, and anatomical features in both twins that are almost mirror images to each other...
Left ventricle to right ventricle size discrepancy in the fetus: the presence of critical congenital heart disease can be reliably predictedMichael D Quartermain
The Cardiac Center at The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
J Am Soc Echocardiogr 22:1296-301. 2009..Prenatal ventricular size discrepancy with disproportionately smaller left ventricle than right ventricle (L-R/VD) can be a marker for important left-sided structural heart disease in the newborn...
A comparison of the efficacy and safety of chloral hydrate versus inhaled anesthesia for sedating infants and toddlers for transthoracic echocardiogramsSusan C Nicolson
Division of Cardiothoracic Anesthesia, The Cardiac Center at The Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104 4399, USA
J Am Soc Echocardiogr 23:38-42. 2010..Pediatric patients may need sedation for a transthoracic echocardiogram. Due to the unpredictability and safety concerns with chloral hydrate, we offered mask anesthesia as an alternate strategy...
Long-term noninvasive arrhythmia assessment after surgical repair of sinus venosus atrial septal defectAndrew C Glatz
Department of Pediatrics, Division of Cardiology, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
Congenit Heart Dis 5:141-8. 2010..Postoperative arrhythmias have not been comprehensively described. We sought to define the prevalence of late arrhythmias after surgical closure of the SVASD...
Usefulness of left ventricular inflow index to predict successful biventricular repair in right-dominant unbalanced atrioventricular canalAnita L Szwast
Division of Cardiology, Department of Pediatrics, Children s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
Am J Cardiol 107:103-9. 2011..We propose incorporation of the LVII into the echocardiographic assessment of these patients...
Accuracy of intraoperative transesophageal echocardiography in the prediction of future neo-aortic valve function after the Ross procedure in children and young adultsBradley S Marino
Children s Hospital of Philadelphia, Pediatrics Divisions of Cardiology, Philadelphia, PA, USA
Congenit Heart Dis 3:39-46. 2008....
Acute cardiovascular effects of fetal surgery in the humanJack Rychik
Center for Fetal Diagnosis and Treatment and the Fetal Heart Program, The Children s Hospital of Philadelphia, 34th St and Civic Center Blvd, Philadelphia, PA 19104, USA
Circulation 110:1549-56. 2004..The indications for fetal surgery continue to expand, yet little is known about the acute sequelae of fetal surgery on the human cardiovascular system...
Influence of congenital heart disease on survival in children with congenital diaphragmatic herniaMeryl S Cohen
Cardiac Center and The Center for Fetal Diagnosis and Treatment, The Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia 19104, USA
J Pediatr 141:25-30. 2002..2 died; 3 of 6 with an LHR >1.2 survived (Fisher exact test, P =.04). CONCLUSION: Heart disease remains a significant risk factor for death in infants with CDH. The LHR helps predict survival in this high-risk group of patients...
Real-time 3-dimensional echocardiographic imaging of congenital heart disease using matrix-array technology: freehand real-time scanning adds instant morphologic details not well delineated by conventional 2-dimensional imagingMohamed A Seliem
Cardiac Center, The Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
J Am Soc Echocardiogr 19:121-9. 2006....
Risk factors for adverse outcomes after surgery on the systemic atrioventricular valve in 109 childrenMatthew J Gillespie
Division of Cardiology, The Children's Hospital of Philadelphia, Pennsylvania 19104, USA
Cardiol Young 16:35-42. 2006
Neo-aortic valvar function after the arterial switchBradley S Marino
Cardiac Center, Children s Hospital of Philadelphia and Department of Pediatrics, University of Pennsylvania School of Medicine, United States of America
Cardiol Young 16:481-9. 2006....
The relationship between neo-aortic root dilation, insufficiency, and reintervention following the Ross procedure in infants, children, and young adultsSara K Pasquali
Division of Cardiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
J Am Coll Cardiol 49:1806-12. 2007..The purpose of this study was to describe the relationship between neo-aortic root size, neo-aortic insufficiency (AI), and reintervention at mid-term follow-up...
Risk factors and comorbidities associated with obesity in children and adolescents after the arterial switch operation and Ross procedureSara K Pasquali
The Division of Cardiology, Department of Pediatrics, The Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
Am Heart J 158:473-9. 2009..Unique factors such as activity restriction and early feeding practices may play a role. We evaluated a high-risk cohort predisposed to early coronary artery disease due to past surgery involving coronary artery reimplantation...
Obesity is a common comorbidity in children with congenital and acquired heart diseaseNelangi M Pinto
Division of Cardiology, Children s Hospital of Philadelphia, 34th Street and Civic Center Boulevard, Philadelphia, PA 19104, USA
Pediatrics 120:e1157-64. 2007..Many children with heart disease are sedentary as a result of physician-, parent-, and/or self-imposed restrictions. The aim of this study was to evaluate the impact of the epidemic of obesity on children with heart disease...
Midterm outcomes and predictors of reintervention after the Ross procedure in infants, children, and young adultsSara K Pasquali
Division of Cardiology in the Departments of Pediatrics, Surgery, and Anesthesia Critical Care Medicine at The Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
J Thorac Cardiovasc Surg 133:893-9. 2007..This study assessed the type, time course, and risk factors for right and left ventricular outflow tract reinterventions after the Ross procedure in a population of infants, children, and young adults...
Atrioventricular valve regurgitation in patients with single ventricle: impact of the bidirectional cavopulmonary anastomosisW T Mahle
Division of Cardiology, The Children s Hospital of Philadelphia, Pennsylvania, USA
Ann Thorac Surg 72:831-5. 2001..It is not known whether atrioventricular valve regurgitation (AVVR) can improve in some patients after the bidirectional cavopulmonary anastomosis (BCPA) without undertaking concomitant valvuloplasty...
Pulmonary outflow tract obstruction in fetuses with complex congenital heart disease: predicting the need for neonatal interventionM D Quartermain
Fetal Heart Program at The Cardiac Center, The Children s Hospital of Philadelphia, Philadelphia, PA, USA
Ultrasound Obstet Gynecol 41:47-53. 2013..To identify prenatal echocardiographic markers that could predict the need for neonatal intervention in fetuses with right ventricular outflow tract obstruction...
Rhythm and conduction disturbances at midterm follow-up after the ross procedure in infants, children, and young adultsSara K Pasquali
Division of Cardiology, Department of Pediatrics, Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
Ann Thorac Surg 85:2072-8. 2008..To our knowledge, late electrophysiologic outcomes after the Ross procedure have not been described. The purpose of this study was to assess rhythm and conduction disturbances at midterm follow-up after the Ross procedure...
Off-label use of cardiovascular medications in children hospitalized with congenital and acquired heart diseaseSara K Pasquali
Division of Cardiology, Department of Pediatrics, Duke University Medical Center and Duke Clinical Research Institute, Durham, NC 27715, USA
Circ Cardiovasc Qual Outcomes 1:74-83. 2008..Recent legislation has aimed to stimulate pediatric research and improve drug labeling. This study describes off-label use of CV medications in children hospitalized with congenital and acquired CV disease...
Chronic hypoxemia increases ventricular brain natriuretic peptide precursors in neonatal swineAzeem R Khan
Division of Cardiothoracic Surgery, Department of Surgery, The Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19106, USA
Ann Thorac Surg 85:618-23. 2008..We evaluated the effect of chronic hypoxemia on left ventricle pro-atrial natriuretic peptide and pro-BNP, the cytoplasmic precursors of the plasma hormones...
