C S Cleeland

Summary

Affiliation: The University of Texas
Country: USA

Publications

  1. doi request reprint Validation and application of the Arabic version of the M. D. Anderson symptom inventory in Moroccan patients with cancer
    Mati Nejmi
    Départment d Anesthésiologie et de Traitment de la Douleur, institut national d oncologie, Rabat, Morocco
    J Pain Symptom Manage 40:75-86. 2010
  2. pmc Validation of the M. D. Anderson Symptom Inventory multiple myeloma module
    Desiree Jones
    Department of Symptom Research, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 1450, 77030, Houston, TX 77030, USA
    J Hematol Oncol 6:13. 2013
  3. doi request reprint Pain outcomes in patients with advanced breast cancer and bone metastases: results from a randomized, double-blind study of denosumab and zoledronic acid
    Charles S Cleeland
    University of Texas, MD Anderson Cancer Center, Department of Symptom Research, Houston, Texas 77030, USA
    Cancer 119:832-8. 2013
  4. doi request reprint Recommendations for including multiple symptoms as endpoints in cancer clinical trials: a report from the ASCPRO (Assessing the Symptoms of Cancer Using Patient-Reported Outcomes) Multisymptom Task Force
    Charles S Cleeland
    Department of Symptom Research, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 119:411-20. 2013
  5. doi request reprint Reducing the toxicity of cancer therapy: recognizing needs, taking action
    Charles S Cleeland
    Department of Symptom Research, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 1450, Houston, TX 77030, USA
    Nat Rev Clin Oncol 9:471-8. 2012
  6. ncbi request reprint Are the symptoms of cancer and cancer treatment due to a shared biologic mechanism? A cytokine-immunologic model of cancer symptoms
    Charles S Cleeland
    Department of Symptom Research, The University of Texas M D Anderson Cancer Center, Houston 77030, USA
    Cancer 97:2919-25. 2003
  7. pmc Automated symptom alerts reduce postoperative symptom severity after cancer surgery: a randomized controlled clinical trial
    Charles S Cleeland
    The University of Texas MD Anderson Cancer Center, Department of Symptom Research, 1515 Holcombe Blvd, Box 1450, Houston, TX 77030, USA
    J Clin Oncol 29:994-1000. 2011
  8. ncbi request reprint Pain assessment: the advantages of using pain scales in lysosomal storage diseases
    C S Cleeland
    Department of Symptom Research, Division of Anesthesiology and Critical Care, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA
    Acta Paediatr Suppl 91:43-7. 2002
  9. pmc Levels of symptom burden during chemotherapy for advanced lung cancer: differences between public hospitals and a tertiary cancer center
    Charles S Cleeland
    The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    J Clin Oncol 29:2859-65. 2011
  10. doi request reprint Integrating pain metrics into oncology clinical trials
    Charles S Cleeland
    Department of Symptom Research, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA
    Clin Cancer Res 17:6646-50. 2011

Collaborators

Detail Information

Publications99

  1. doi request reprint Validation and application of the Arabic version of the M. D. Anderson symptom inventory in Moroccan patients with cancer
    Mati Nejmi
    Départment d Anesthésiologie et de Traitment de la Douleur, institut national d oncologie, Rabat, Morocco
    J Pain Symptom Manage 40:75-86. 2010
    ..Little is known about symptom burden-a concept encompassing both symptom severity and the degree of symptom interference with daily living-in patients with cancer in Morocco or other countries with Arabic-speaking populations...
  2. pmc Validation of the M. D. Anderson Symptom Inventory multiple myeloma module
    Desiree Jones
    Department of Symptom Research, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 1450, 77030, Houston, TX 77030, USA
    J Hematol Oncol 6:13. 2013
    ..We sought to validate a module of the M. D. Anderson Symptom Inventory (MDASI) developed specifically for patients with MM (MDASI-MM)...
  3. doi request reprint Pain outcomes in patients with advanced breast cancer and bone metastases: results from a randomized, double-blind study of denosumab and zoledronic acid
    Charles S Cleeland
    University of Texas, MD Anderson Cancer Center, Department of Symptom Research, Houston, Texas 77030, USA
    Cancer 119:832-8. 2013
    ..In this study, the authors evaluated the effect of denosumab versus zoledronic acid (ZA) on pain in patients with advanced breast cancer and bone metastases...
  4. doi request reprint Recommendations for including multiple symptoms as endpoints in cancer clinical trials: a report from the ASCPRO (Assessing the Symptoms of Cancer Using Patient-Reported Outcomes) Multisymptom Task Force
    Charles S Cleeland
    Department of Symptom Research, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 119:411-20. 2013
    ..A representation of changes in multiple symptoms would clarify the impact of treatment and enhance the interpretation of cancer clinical trials for clinicians, patients, and those who make health care policy...
  5. doi request reprint Reducing the toxicity of cancer therapy: recognizing needs, taking action
    Charles S Cleeland
    Department of Symptom Research, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 1450, Houston, TX 77030, USA
    Nat Rev Clin Oncol 9:471-8. 2012
    ..With an emphasis on coordinating multidisciplinary efforts, this panel has presented a strategy to increase funding for the field and develop a coherent research agenda...
  6. ncbi request reprint Are the symptoms of cancer and cancer treatment due to a shared biologic mechanism? A cytokine-immunologic model of cancer symptoms
    Charles S Cleeland
    Department of Symptom Research, The University of Texas M D Anderson Cancer Center, Houston 77030, USA
    Cancer 97:2919-25. 2003
    ..These symptoms include pain, wasting, fatigue, cognitive impairment, anxiety, and depression, many of which co-occur. There is growing recognition that at least some of these symptoms may share common biologic mechanisms...
  7. pmc Automated symptom alerts reduce postoperative symptom severity after cancer surgery: a randomized controlled clinical trial
    Charles S Cleeland
    The University of Texas MD Anderson Cancer Center, Department of Symptom Research, 1515 Holcombe Blvd, Box 1450, Houston, TX 77030, USA
    J Clin Oncol 29:994-1000. 2011
    ..This study examined whether at-home symptom monitoring plus feedback to clinicians about severe symptoms contributes to more effective postoperative symptom control...
  8. ncbi request reprint Pain assessment: the advantages of using pain scales in lysosomal storage diseases
    C S Cleeland
    Department of Symptom Research, Division of Anesthesiology and Critical Care, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA
    Acta Paediatr Suppl 91:43-7. 2002
    ..The BPI also measures the effect of pain on daily activity and quality of life, defines the location of pain and assesses the effectiveness of previous pain relief medication...
  9. pmc Levels of symptom burden during chemotherapy for advanced lung cancer: differences between public hospitals and a tertiary cancer center
    Charles S Cleeland
    The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    J Clin Oncol 29:2859-65. 2011
    ..We compared risk factors for high disease- and treatment-related symptom burden over 15 weeks of therapy in medically underserved patients with advanced non-small-cell lung cancer and in patients treated at a tertiary cancer center...
  10. doi request reprint Integrating pain metrics into oncology clinical trials
    Charles S Cleeland
    Department of Symptom Research, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA
    Clin Cancer Res 17:6646-50. 2011
    ..A number of methodologic and logistical challenges that hinder the ability to assess pain response in clinical trials are discussed in this article. Possible ways to address these challenges are also discussed...
  11. ncbi request reprint When is it justified to treat symptoms? Measuring symptom burden
    Charles S Cleeland
    Department of Symptom Research, The University of Texas M D Anderson Cancer Center, Houston 77030, USA
    Oncology (Williston Park) 16:64-70. 2002
    ..Finally, we discuss potential research challenges and offer recommendations on future research directions...
  12. ncbi request reprint Cancer pain management by radiotherapists: a survey of radiation therapy oncology group physicians
    C S Cleeland
    Pain Research Group, The University of Texas M D Anderson Cancer Center, Houston, TX, USA
    Int J Radiat Oncol Biol Phys 47:203-8. 2000
    ..Radiation Therapy Oncology Group (RTOG) physicians were surveyed to determine their approach to and attitudes toward cancer pain management...
  13. ncbi request reprint Does an oral analgesic protocol improve pain control for patients with cancer? An intergroup study coordinated by the Eastern Cooperative Oncology Group
    C S Cleeland
    The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Ann Oncol 16:972-80. 2005
    ..Cancer pain is highly prevalent and commonly undertreated. This study was designed to determine whether dissemination of a clinical protocol for pain management would improve outcomes in community oncology practices...
  14. ncbi request reprint The measurement of pain from metastatic bone disease: capturing the patient's experience
    Charles S Cleeland
    Department of Symptom Research, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Clin Cancer Res 12:6236s-6242s. 2006
    ..These and other considerations in the design of clinical trials are discussed...
  15. ncbi request reprint Assessing symptom distress in cancer patients: the M.D. Anderson Symptom Inventory
    C S Cleeland
    Pain Research Group, Division of Anesthesiology and Critical Care, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 89:1634-46. 2000
    ..The purpose of this project was to develop the M. D. Anderson Symptom Inventory (MDASI), a brief measure of the severity and impact of cancer-related symptoms...
  16. ncbi request reprint Rapid improvement in pain management: the Veterans Health Administration and the institute for healthcare improvement collaborative
    Charles S Cleeland
    Pain Research Group, Department of Symptom Research, U T M D Anderson Cancer Center, Houston, Texas, USA
    Clin J Pain 19:298-305. 2003
    ..With the goal of rapid improvement in pain management, a joint Collaborative (Veterans Health Administration and Institute for Healthcare Improvement) was conducted from May 2000 to January 2001...
  17. ncbi request reprint End-of-life care in urban areas of China: a survey of 60 oncology clinicians
    Xin Shelley Wang
    Department of Symptom Research, World Health Organization s Collaborating Center on Supportive Cancer Care, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    J Pain Symptom Manage 27:125-32. 2004
    ..Results of the survey suggest specific training and research in symptom management that might improve end-of-life care for Chinese cancer patients...
  18. ncbi request reprint Adequacy of cancer pain management in a Japanese Cancer Hospital
    Toru Okuyama
    Department of Symptom Research, Division of Anesthesiology and Critical Care, University of Texas M D Anderson Cancer Center, Houston, TX, USA
    Jpn J Clin Oncol 34:37-42. 2004
    ..Pain is one of the most frequent and deleterious symptoms in cancer patients. This study was carried out to investigate the adequacy of pain management at the National Cancer Center Hospital East, Japan...
  19. doi request reprint Clinical benefit in patients with metastatic bone disease: results of a phase 3 study of denosumab versus zoledronic acid
    S Vadhan-Raj
    Division of Cancer Medicine, Department of Sarcoma Medical Oncology and Lymphoma Myeloma, Section of Cytokines and Supportive Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Ann Oncol 23:3045-51. 2012
    ....
  20. ncbi request reprint A fatigue clinic in a comprehensive cancer center: design and experiences
    C P Escalante
    Department of General Internal Medicine, Ambulatory Treatment and Emergency Care, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 92:1708-13. 2001
    ..This article describes the general clinic design and operations and the preliminary analysis of the first 40 patients evaluated in the fatigue clinic...
  21. doi request reprint The M. D. Anderson symptom inventory-head and neck module, a patient-reported outcome instrument, accurately predicts the severity of radiation-induced mucositis
    David I Rosenthal
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX, USA
    Int J Radiat Oncol Biol Phys 72:1355-61. 2008
    ....
  22. pmc Temporal patterns of fatigue predict pathologic response in patients treated with preoperative chemoradiation therapy for rectal cancer
    Hee Chul Park
    Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030 4009, USA
    Int J Radiat Oncol Biol Phys 75:775-81. 2009
    ..To investigate whether symptom burden before and during preoperative chemoradiation therapy (CRT) for rectal cancer predicts for pathologic tumor response...
  23. ncbi request reprint Validation study of the Chinese version of the Brief Fatigue Inventory (BFI-C)
    Xin Shelley Wang
    Department of Symptom Research, Division of Anesthesiology and Critical Care, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    J Pain Symptom Manage 27:322-32. 2004
    ..The BFI-C is a valid, reliable instrument to measure the severity and impact of cancer-related fatigue among Chinese patients...
  24. ncbi request reprint Fatigue during preoperative chemoradiation for resectable rectal cancer
    X S Wang
    Pain Research Group, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 92:1725-32. 2001
    ..Based on identified predictors for fatigue, more active pain management before CXT/XRT and bowel management during CTX/XRT might reduce cancer-related fatigue in these patients...
  25. ncbi request reprint Symptom burden in patients undergoing autologous stem-cell transplantation
    K O Anderson
    Department of Symptom Research, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Bone Marrow Transplant 39:759-66. 2007
    ..The patterns of fatigue, pain, sleep disturbance and lack of appetite were significantly different for patients with multiple myeloma as compared with patients with non-Hodgkin's lymphoma...
  26. ncbi request reprint Measuring head and neck cancer symptom burden: the development and validation of the M. D. Anderson symptom inventory, head and neck module
    David I Rosenthal
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas, USA
    Head Neck 29:923-31. 2007
    ....
  27. ncbi request reprint An urban community's preferences for hypothetical outcomes of analgesic pain treatment
    Guadalupe R Palos
    Department of Symptom Research, University of Texas M D Anderson Cancer Center, Houston, TX 77030 4009, USA
    J Pain Symptom Manage 32:470-7. 2006
    ..Knowledge of public preferences can help clinicians better understand factors that influence treatment choices and may help them motivate their patients to adhere to analgesic regimens...
  28. ncbi request reprint What predicts the quality of advanced cancer care in Latin America? A look at five countries: Argentina, Brazil, Cuba, Mexico, and Peru
    Isabel Torres Vigil
    Center for Research on Minority Health, Department of Health Disparities Research, University of Texas M D Anderson Cancer Center, Houston, Texas 77021, USA
    J Pain Symptom Manage 34:315-27. 2007
    ....
  29. ncbi request reprint Lessons learned from a multiple-dose post-operative analgesic trial
    Tito R Mendoza
    Pain Research Group, Department of Symptom Research, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Box 221, Houston, TX 77030, USA
    Pain 109:103-9. 2004
    ....
  30. ncbi request reprint Longitudinal study of the relationship between chemoradiation therapy for non-small-cell lung cancer and patient symptoms
    Xin Shelley Wang
    Department of Symptom Research, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    J Clin Oncol 24:4485-91. 2006
    ....
  31. pmc Pain in aging community-dwelling adults in the United States: non-Hispanic whites, non-Hispanic blacks, and Hispanics
    Cielito C Reyes-Gibby
    Department of Epidemiology, UT MD Anderson Cancer Center, Houston, TX 77030 4009, USA
    J Pain 8:75-84. 2007
    ..54-2.43), being a Medicaid recipient (OR, 1.63; 99% CI, 1.17-2.25), and lower educational level (OR, 1.45; 99% CI, 1.14-1.85) were significant predictors for severe pain and helped to explain racial/ethnic differences in pain severity...
  32. doi request reprint Symptom burden in cancer survivorship
    V Shannon Burkett
    The Department of Symptom Research, The University of Texas M D Anderson Cancer Center, 1100 Holcombe Blvd, Unit 221, Houston, TX 77030, USA
    J Cancer Surviv 1:167-75. 2007
    ..This paper contrasts symptom burden with general HRQOL and addresses the importance of including symptom burden as research tool throughout the trajectory of cancer survivorship...
  33. pmc Assessing persistent cancer pain: a comparison of current pain ratings and pain recalled from the past week
    Qiuling Shi
    Department of Symptom Research, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    J Pain Symptom Manage 37:168-74. 2009
    ..Our results provide information that might guide the choice of recall period for cancer clinical trials with pain as a self-reported outcome...
  34. pmc Caregiver symptom burden: the risk of caring for an underserved patient with advanced cancer
    Guadalupe R Palos
    Department of Symptom Research, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 117:1070-9. 2011
    ..In this longitudinal study, the authors assessed changes in symptom severity in caregivers and underserved minority patients diagnosed with advanced solid tumors who were being treated at public hospitals...
  35. doi request reprint Biological pathways and genetic variables involved in pain
    Qiuling Shi
    Department of Symptom Research, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Unit 1450, Houston, TX 77030, USA
    Qual Life Res 19:1407-17. 2010
    ..This paper summarizes current knowledge of pain-related and analgesic-related pathways as well as genetic variations involved in pain perception and management...
  36. pmc Does recall period have an effect on cancer patients' ratings of the severity of multiple symptoms?
    Qiuling Shi
    Department of Symptom Research, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA
    J Pain Symptom Manage 40:191-9. 2010
    ..Choosing an appropriate recall period for symptom assessment in a clinical trial is dependent on the design and purpose of the trial...
  37. pmc Inflammatory cytokines are associated with the development of symptom burden in patients with NSCLC undergoing concurrent chemoradiation therapy
    Xin Shelley Wang
    Department of Symptom Research, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Brain Behav Immun 24:968-74. 2010
    ....
  38. doi request reprint Assessment of fatigue in cancer patients and community dwellers: validation study of the Filipino version of the brief fatigue inventory
    Tito R Mendoza
    Department of Symptom Research, Division of Internal Medicine, The University of Texas MD Anderson Cancer Center, Houston, Tex 77030, USA
    Oncology 79:112-7. 2010
    ..We developed and validated a Filipino language version of the Brief Fatigue Inventory (BFI-F) for describing the prevalence and severity of fatigue among Filipino patients with cancer...
  39. pmc Impact of cultural and linguistic factors on symptom reporting by patients with cancer
    Xin Shelley Wang
    Department of Symptom Research, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Unit 1450, Houston, TX 77030, USA
    J Natl Cancer Inst 102:732-8. 2010
    ..In multinational clinical trials, cultural and linguistic variations in patient-reported outcomes instruments could confound the interpretation of study results...
  40. pmc Measuring the symptom burden of lung cancer: the validity and utility of the lung cancer module of the M. D. Anderson Symptom Inventory
    Tito R Mendoza
    Department of Symptom Research, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 1450, Houston, Texas 77030, USA
    Oncologist 16:217-27. 2011
    ....
  41. doi request reprint Validation and application of a module of the M. D. Anderson Symptom Inventory for measuring multiple symptoms in patients with gastrointestinal cancer (the MDASI-GI)
    Xin Shelley Wang
    Department of Symptom Research, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 116:2053-63. 2010
    ..The authors report the development of an MDASI module for use in patients with gastrointestinal (GI) cancer (the MDASI-GI)...
  42. pmc Prognostic value of symptom burden for overall survival in patients receiving chemotherapy for advanced nonsmall cell lung cancer
    Xin Shelley Wang
    Department of Symptom Research, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Cancer 116:137-45. 2010
    ..However, translating patient-reported outcomes into useful prognostic information for individual patients has been problematic...
  43. ncbi request reprint Health care providers' assessments of the quality of advanced-cancer care in Latin American medical institutions: a comparison of predictors in five countries: Argentina, Brazil, Cuba, Mexico, and Peru
    Isabel Torres-Vigil
    Department of Health Disparities Research, Center for Research on Minority Health at The University of Texas M D Anderson Cancer Center, Houston, TX 77021, USA
    J Pain Palliat Care Pharmacother 22:7-20. 2008
    ....
  44. pmc Serum interleukin-6 predicts the development of multiple symptoms at nadir of allogeneic hematopoietic stem cell transplantation
    Xin Shelley Wang
    Department of Symptom Research, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 113:2102-9. 2008
    ..However, the mechanism underlying the development of multiple symptoms has not been established...
  45. pmc Pain, depression, and fatigue in community-dwelling adults with and without a history of cancer
    Cielito C Reyes-Gibby
    Department of Epidemiology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77230 1439, USA
    J Pain Symptom Manage 32:118-28. 2006
    ..21; 95%CI = 1.06,1.37), and pain (OR = 1.15; 95%CI = 1.03,1.28). Symptom clusters were also more prevalent among those with a history of cancer (P < 0.001), with the pain-depression-fatigue cluster as most prevalent...
  46. ncbi request reprint Pain and fatigue in community-dwelling adults
    Cielito C Reyes-Gibby
    Department of Symptom Research, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Pain Med 4:231-7. 2003
    ..We also assessed the prevalence of mild, moderate, and severe fatigue for this sample...
  47. ncbi request reprint Pain education for underserved minority cancer patients: a randomized controlled trial
    Karen O Anderson
    Department of Symptom Research, The University of Texas M D Anderson Cancer Center, 1100 Holcombe Blvd, Box 221, Houston, TX 77030, USA
    J Clin Oncol 22:4918-25. 2004
    ..Previous studies found that African American and Hispanic cancer patients are at risk for undertreatment of pain. We evaluated the efficacy of a pain education intervention for underserved minority patients...
  48. ncbi request reprint Changes in plasma levels of inflammatory cytokines in response to paclitaxel chemotherapy
    Lajos Pusztai
    Department of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Cytokine 25:94-102. 2004
    ..The objective of this study was to assess changes in plasma levels of interleukin (IL)-1beta, IL-6, IL-8, IL-10, IL-12, and TNF-alpha during chemotherapy and to correlate these changes with musculoskeletal symptoms...
  49. ncbi request reprint Fatigue and sleep disturbance in patients with cancer, patients with clinical depression, and community-dwelling adults
    Karen O Anderson
    Department of Symptom Research, Division of Anesthesiology and Critical Care, The University of Texas M D Anderson Cancer Center, 1100 Holcombe Boulevard, Box 221, Houston, TX 77030, USA
    J Pain Symptom Manage 25:307-18. 2003
    ..Although the majority of the psychiatric patients reported sleep disturbance, their sleep disturbance scores were not significantly associated with fatigue severity...
  50. ncbi request reprint Asking the community about cutpoints used to describe mild, moderate, and severe pain
    Guadalupe R Palos
    Department of Symptom Research, The University of Texas MD Anderson Cancer Center, Houston, 77030, USA
    J Pain 7:49-56. 2006
    ..Our findings also support encouraging the general public to use a 0 to 10 scale to rate their pain intensity...
  51. ncbi request reprint Chinese version of the M. D. Anderson Symptom Inventory: validation and application of symptom measurement in cancer patients
    Xin Shelley Wang
    Division of Internal Medicine, Department of Symptom Research, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 101:1890-901. 2004
    ..Because disease-related and treatment-related symptoms most often occur in clusters, there is a global need for a standardized multiple-symptom assessment tool...
  52. ncbi request reprint The utility and validity of the modified brief pain inventory in a multiple-dose postoperative analgesic trial
    Tito R Mendoza
    Pain Research Group, Department of Symptom Research, University of Texas MD Anderson Cancer Center, Houston 77030, USA
    Clin J Pain 20:357-62. 2004
    ..Our objective was to validate use of the modified Brief Pain Inventory through reanalysis of pain data from a multiple-dose, placebo-controlled, randomized trial of analgesia after coronary artery bypass graft surgery...
  53. ncbi request reprint Pain and quality of life after treatment in patients with locally recurrent rectal cancer
    Nestor F Esnaola
    Department of Surgery, Pain Research Group, The University of Texas M D Anderson Cancer Center, Houston 77030 4009, USA
    J Clin Oncol 20:4361-7. 2002
    ..The purpose of this study was to assess the prevalence of posttreatment pain and QOL of patients with LRRC treated with nonsurgical palliation or resection and identify predictors of poor outcome...
  54. ncbi request reprint Cancer pain management among underserved minority outpatients: perceived needs and barriers to optimal control
    Karen O Anderson
    Department of Symptom Research, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 94:2295-304. 2002
    ..Structured interviews allowed the authors to probe for previously unidentified barriers to pain management in these populations...
  55. ncbi request reprint Clinical factors associated with cancer-related fatigue in patients being treated for leukemia and non-Hodgkin's lymphoma
    Xin Shelley Wang
    Department of Symptom Research, Division of Anesthesiology and Critical Care, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    J Clin Oncol 20:1319-28. 2002
    ..To describe fatigue severity, fatigue interference, and associated factors in hematologic malignancies...
  56. ncbi request reprint Filipino version of the M. D. Anderson Symptom Inventory: validation and multisymptom measurement in cancer patients
    Xin Shelley Wang
    Department of Symptom Research X S W, H G, T R M, C S C, Division of Internal Medicine, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    J Pain Symptom Manage 31:542-52. 2006
    ..Cancer patients reported significantly greater symptom severity on multiple items than did the community sample. The MDASI-F is reliable and valid for evaluating cancer-related symptoms and their impact on Filipino cancer patients...
  57. ncbi request reprint Brief cognitive-behavioral audiotape interventions for cancer-related pain: Immediate but not long-term effectiveness
    Karen O Anderson
    Department of Symptom Research, Division of Internal Medicine, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 107:207-14. 2006
    ..A randomized clinical trial was performed evaluating the efficacy of 3 brief cognitive-behavioral techniques: relaxation, distraction, and positive mood interventions...
  58. ncbi request reprint The association between symptom burdens and utility in Chinese cancer patients
    Ya Chen Tina Shih
    Section of Health Services Research, Department of Biostatistics and Applied Mathematics, The University of Texas M D Anderson Cancer Center, Houston, TX 77030 4009, USA
    Qual Life Res 15:1427-38. 2006
    ..This study explored the relationship between the M. D. Anderson Symptom Inventory (MDASI), an instrument measuring the severity of symptoms common to patients with cancer, and utility derived from the SF-36...
  59. doi request reprint Psychometric testing of the MDASI-HF: a symptom assessment instrument for patients with cancer and concurrent heart failure
    Anecita Fadol
    Department of Cardiology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    J Card Fail 14:497-507. 2008
    ..This study evaluated the psychometric properties of the MD Anderson Symptom Inventory--Heart Failure (MDASI-HF), a 27-item self-report assessment instrument for patients with cancer and concurrent HF...
  60. ncbi request reprint Pediatric cancer pain management practices and attitudes in China
    Xin Shelley Wang
    Department of Symptom Research, Division of Anesthesiology and Critical Care, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    J Pain Symptom Manage 26:748-59. 2003
    ..10, CI=1.31-3.37), and belief that children are less sensitive to pain (OR=1.96, CI=1.02-3.76). The top barriers to optimal pediatric pain management were identified as fear of opioid addiction and inadequate knowledge of pain management...
  61. ncbi request reprint Japanese version of the MD Anderson Symptom Inventory: a validation study
    Toru Okuyama
    Department of Symptom Research, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA
    J Pain Symptom Manage 26:1093-104. 2003
    ..Both factor analysis and cluster analysis showed the consistency of the statistical structure of the English and Japanese versions, indicating the cross-cultural validity of the scale...
  62. ncbi request reprint A preliminary study of the utility of the brief hospice inventory
    H Guo
    Pain Research Group, The University of Texas M. D. Anderson Cancer Center, 1100 Holcombe Blvd. Houston, TX 77030, USA
    J Pain Symptom Manage 22:637-48. 2001
    ..The BHI shows utility in measuring hospice patients' symptom severity and quality of life over time...
  63. doi request reprint Assessing the Symptoms of Cancer Using Patient-Reported Outcomes (ASCPRO): searching for standards
    Charles S Cleeland
    Department of Symptom Research, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA
    J Pain Symptom Manage 39:1077-85. 2010
    ....
  64. doi request reprint Clinical utility of the MDASI-BT in patients with brain metastases
    Terri S Armstrong
    Department of Integrative Nursing Care, The University of Texas Health Science Center School of Nursing, Houston, Texas 77030, USA
    J Pain Symptom Manage 37:331-40. 2009
    ..The MDASI-BT demonstrated validity and reliability in brain metastases patients and can be used to identify and monitor symptom occurrence in relation to treatment course and survival...
  65. ncbi request reprint Variations in patients' self-report of pain by treatment setting
    Cielito C Reyes-Gibby
    Pain Research Group, Department of Symptom Research, University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    J Pain Symptom Manage 25:444-8. 2003
    ....
  66. ncbi request reprint Validation study of the Japanese version of the brief fatigue inventory
    Toru Okuyama
    Pain Research Group, Division of Anesthesiology and Critical Care, The University of Texas M D Anderson Cancer Center, Houston, TX, USA
    J Pain Symptom Manage 25:106-17. 2003
    ..Additionally, fatigue severity classification was explored using the BFI-J. The results indicated that the BFI-J is a brief, valid, and feasible measure of fatigue for use with Japanese cancer patients...
  67. ncbi request reprint A cytokine-based neuroimmunologic mechanism of cancer-related symptoms
    Bang Ning Lee
    Department of Hematopathology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Neuroimmunomodulation 11:279-92. 2004
    ..These concepts open exciting new avenues for translational research in the pathophysiology and treatment of cancer-related symptoms...
  68. ncbi request reprint Perceptions of analgesic use and side effects: what the public values in pain management
    Guadalupe R Palos
    Department of Symptom Research, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030 4009, USA
    J Pain Symptom Manage 28:460-73. 2004
    ..To achieve better pain outcomes, clinicians and patients must identify factors that contribute to conservative decision-making about analgesic use and side effect management...
  69. doi request reprint Assessment of cancer-related neuropathy and neuropathic pain
    Charles S Cleeland
    University of Texas MD Anderson Cancer Center, Houston, Texas, USA
    Oncologist 15:13-8. 2010
    ....
  70. ncbi request reprint The role of statins in cancer therapy
    Katja Hindler
    Division of Cardiovascular Anesthesiology, the Texas Heart Institute at St Luke s Episcopal Hospital, 6720 Bertner Avenue, Houston, Texas 77030, USA
    Oncologist 11:306-15. 2006
    ..The feasibility and efficacy of statins for the prevention and treatment of cancer is reviewed...
  71. doi request reprint Development and initial validation of the thyroid cancer module of the M. D. Anderson Symptom Inventory
    Ibrahima Gning
    Department of Symptom Research, The University of Texas M D Anderson Cancer Center, Houston, Tex 77030, USA
    Oncology 76:59-68. 2009
    ..The M. D. Anderson Symptom Inventory (MDASI) and its modules measure common symptoms related to cancer and its treatment. We report the development and initial validation of the MDASI-Thyroid Cancer module (MDASI-THY)...
  72. ncbi request reprint People in pain: how do they seek relief?
    Qiuling Shi
    Department of Symptom Research, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    J Pain 8:624-36. 2007
    ..Difficulty communicating with health professionals and lack of health insurance contributed to inadequate pain relief. Almost all people with pain used multiple methods to control their pain...
  73. ncbi request reprint Management of cancer pain
    Allen W Burton
    JAMA 291:1067-8; author reply 1068-9. 2004
  74. ncbi request reprint Cancer-related symptom assessment in Russia: validation and utility of the Russian M. D. Anderson Symptom Inventory
    Maria O Ivanova
    National Cancer Research and Treatment Center, St Petersburg, Russia
    J Pain Symptom Manage 30:443-53. 2005
    ..Medical professionals underestimated the severity of pain, fatigue, and distress. The MDASI-R is valid and reliable for measuring symptom severity and interference in Russian cancer patients...
  75. ncbi request reprint The analgesic effects that underlie patient satisfaction with treatment
    Mark P Jensen
    Department of Rehabilitation Medicine, School of Medicine, University of Washington, Seattle 98195 6490, USA
    Pain 110:480-7. 2004
    ..g. decreased pain, opioid-related symptoms) mediated, in part, the effects of treatment on treatment satisfaction...
  76. ncbi request reprint [Validation of the Spanish version of the Brief Pain Inventory in patients with oncological pain]
    Xavier Badia
    Unitat de Recerca en Resultats en Salut, Servei d Epidemiologia Clínica i Salut Pública, Hospital de la Santa Creu i Sant Pau, Barcelona, Espana
    Med Clin (Barc) 120:52-9. 2003
    ..Our goal was to validate the Spanish version of the Brief Pain Inventory (BPI) questionnaire used to measure the intensity of oncological pain and its impact on activities of daily living in patients with cancer...
  77. ncbi request reprint The Norwegian brief pain inventory questionnaire: translation and validation in cancer pain patients
    Pål Klepstad
    Department of Anesthesiology and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway
    J Pain Symptom Manage 24:517-25. 2002
    ....
  78. doi request reprint Pain and suffering during cancer therapy: continued sins of omission
    Nora A Janjan
    Int J Radiat Oncol Biol Phys 72:6-8. 2008
  79. ncbi request reprint Validity of the brief pain inventory for use in documenting the outcomes of patients with noncancer pain
    San Keller
    American Institutes for Research, Chapel Hill, NC 27514 2825, USA
    Clin J Pain 20:309-18. 2004
    ..The current research addresses the need for formal evaluation of the reliability and validity of the BPI for use in non-cancer pain patients...
  80. ncbi request reprint Development of a cancer pain assessment tool in Korea: a validation study of a Korean version of the brief pain inventory
    Young Ho Yun
    Research Institute and Hospital, National Cancer Center, Goyang, Korea
    Oncology 66:439-44. 2004
    ..The aim of this study was to validate the Korean version of the Brief Pain Inventory (BPI-K), a pain assessment tool that has been validated in several languages...
  81. ncbi request reprint Validation study of the Korean version of the M. D. Anderson Symptom Inventory
    Young Ho Yun
    Quality of Cancer Care Branch, Research Institute and Hospital, National Cancer Center, Goyang, Gyeonggi, Korea
    J Pain Symptom Manage 31:345-52. 2006
    ..The MDASI-K is a valid and reliable measure for assessing multiple symptoms in Korean cancer patients...
  82. ncbi request reprint Clinicians' practice and attitudes toward cancer pain management in Korea
    Yeon Soo Jeon
    Department of Anesthesiology and Pain Medicine, Saint Vincent s Hospital, The Catholic University of Korea, 93 6 Chi Dong, Paldal Gu, Suwon, South Korea
    Support Care Cancer 15:463-9. 2007
    ..The purposes of this study were to assess clinicians' (n = 250) current practices and attitudes about cancer pain management and to identify perceived concerns about and barriers to pain control in urban cancer-treatment settings in Korea...
  83. ncbi request reprint Taiwanese version of the M. D. Anderson symptom inventory: symptom assessment in cancer patients
    Chia Chin Lin
    Graduate Institute of Nursing, Taipei Medical University, Tainan, Taiwan
    J Pain Symptom Manage 33:180-8. 2007
    ..The MDASI-T is a reliable, valid, and sensitive instrument for measuring the severity and interference with daily life of cancer-related symptoms among Taiwanese cancer patients...
  84. ncbi request reprint Assessment of clinical relevant fatigue level in cancer
    Yoon Jung Chang
    Research Institute for National Cancer Control and Evaluation, National Cancer Center, Goyang, Gyeonggi, South Korea
    Support Care Cancer 15:891-6. 2007
    ....
  85. ncbi request reprint Symptoms in the lives of terminal cancer patients: which is the most important?
    Yong Chol Kwon
    Research Institute and Hospital, National Cancer Center, Goyang, Gyeonggi, Korea
    Oncology 71:69-76. 2006
    ..Symptoms other than their primary disease can interfere in the lives of terminal cancer patients. We sought to identify which of these symptoms is most important...
  86. ncbi request reprint Long-term use of controlled-release oxycodone for noncancer pain: results of a 3-year registry study
    Russell K Portenoy
    Department of Pain Medicine and Palliative Care, Beth Israel Medical Center, New York, NY 10003, USA
    Clin J Pain 23:287-99. 2007
    ..To evaluate the outcomes associated with the use of controlled-release (CR) oxycodone for up to 3 years in the treatment of noncancer pain...
  87. ncbi request reprint Randomized trial of short- versus long-course radiotherapy for palliation of painful bone metastases
    William F Hartsell
    Advocate Good Samaritan Hospital, Downers Grove, IL, USA
    J Natl Cancer Inst 97:798-804. 2005
    ..We investigated whether 8 Gy delivered in a single treatment fraction provides pain and narcotic relief that is equivalent to that of the standard treatment course of 30 Gy delivered in 10 treatment fractions over 2 weeks...
  88. ncbi request reprint Assessing symptom burden using the M. D. Anderson symptom inventory in patients with chemotherapy-induced anemia: results of a multicenter, open-label study (SURPASS) of patients treated with darbepoetin-alpha at a dose of 200 microg every 2 weeks
    Janice L Gabrilove
    Division of Hematology Oncology, Mount Sinai Medical Center, New York, New York, USA
    Cancer 110:1629-40. 2007
    ....
  89. ncbi request reprint Identifying important outcome domains for chronic pain clinical trials: an IMMPACT survey of people with pain
    Dennis C Turk
    Department of Anesthesiology, University of Washington, Seattle, WA 98195, USA
    Pain 137:276-85. 2008
    ..These multiple outcomes should be considered when evaluating the efficacy and effectiveness of chronic pain treatments...
  90. ncbi request reprint Russian Brief Pain Inventory: validation and application in cancer pain
    Svetlana A Kalyadina
    National Cancer Research and Treatment Center, St Petersburg, Russia
    J Pain Symptom Manage 35:95-102. 2008
    ..Having advanced-stage disease and not receiving chemotherapy predicted inadequate pain management in a multivariate logistic regression model. The Russian version of the BPI is psychometrically sound in its reliability and validity...
  91. pmc Patient training in cancer pain management using integrated print and video materials: a multisite randomized controlled trial
    Karen L Syrjala
    Biobehavioral Sciences, Clinical Research Division, Fred Hutchinson Cancer Research Center, D5 220, 1100 Fairview Avenue N, Seattle, WA 98109, USA
    Pain 135:175-86. 2008
    ..Using video and print materials, with brief individualized training, effectively improved pain management over time for cancer patients of varying diagnostic and demographic groups...
  92. ncbi request reprint Validation study of the korean version of the brief fatigue inventory
    Young Ho Yun
    Quality of Cancer Care Branch, Research Institute and Hospital, National Cancer Center, Goyang, Gyeonggi, Korea
    J Pain Symptom Manage 29:165-72. 2005
    ..Our study has shown that the BFI-K is a reliable, valid self-rating instrument in terms of its psychometric properties...
  93. doi request reprint Assessing cancer symptoms in adolescents with cancer using the Taiwanese version of the M. D. Anderson Symptom Inventory
    Tsui Hwa Tseng
    Graduate Institute of Medical Sciences, Taipei Medical University, Taipei, Taiwan
    Cancer Nurs 31:E9-16. 2008
    ..This study provides evidence that the MDASI-T is a reliable and valid instrument for measuring cancer-related symptoms in Taiwanese adolescents with cancer...
  94. doi request reprint Fatigue in the general Korean population: application and normative data of the Brief Fatigue Inventory
    Young Ho Yun
    Division of Cancer Control, National Cancer Control Research Institute, National Cancer Center, Goyang, Gyeonggi, Korea
    J Pain Symptom Manage 36:259-67. 2008
    ..Our findings indicate that comorbidities should be considered when comparing fatigue data from the general population with data from patients...
  95. ncbi request reprint Patient-reported outcomes: instrument development and selection issues
    Ralph R Turner
    Phase V Technologies Inc, Wellesley Hills, MA, USA
    Value Health 10:S86-93. 2007
    ..Finally, PRO assessment is meaningless if the key figure chooses not to cooperate. We consider how respondent burden influences the quality of PRO assessment...
  96. ncbi request reprint Validation of the Taiwanese version of the Brief Fatigue Inventory
    Chia Chin Lin
    Graduate Institute of Nursing, Taipei Medical University, Taipei, Taiwan, ROC
    J Pain Symptom Manage 32:52-9. 2006
    ..The BFI-T is reliable, valid, and sensitive for measuring cancer-related fatigue severity and interference among Taiwanese cancer patients...
  97. ncbi request reprint Health-related quality of life and symptom assessment in clinical research of patients with hematologic malignancies: where are we now and where do we go from here?
    Fabio Efficace
    Haematologica 92:1596-8. 2007
  98. ncbi request reprint Interpreting the clinical importance of treatment outcomes in chronic pain clinical trials: IMMPACT recommendations
    Robert H Dworkin
    Department of Anesthesiology, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
    J Pain 9:105-21. 2008
    ..Provisional benchmarks for identifying clinically important changes in specific outcome measures that can be used for outcome studies of treatments for chronic pain are proposed...
  99. pmc Advances in treating metastatic bone cancer: summary statement for the First Cambridge Conference
    Allan Lipton
    Milton S Hershey Medical Center, Penn State University College of Medicine, Hershey, Pennsylvania 17033 0850, USA, and Department of Oncology, Norwegian Radium Hospital, Oslo, Norway
    Clin Cancer Res 12:6209s-6212s. 2006
    ..The conclusions reached during the 2-day meeting are summarized in this article and presented in more detail in the individual articles and accompanying discussion sessions that comprise the conference proceedings...

Research Grants17

  1. Understanding the Impact of Multiple Symptoms: A Symptom Burden Consortium
    Charles Cleeland; Fiscal Year: 2006
    ..The document will be a collaborative effort among consortium participants, and will be submitted to a leading scientific peer-reviewed journal. ..
  2. Reducing the Symptom Burden Produced by Aggressive Cancer Therapies
    Charles Cleeland; Fiscal Year: 2009
    ..The ultimate goal of this research is to be able to administer the best available curative therapy to the largest number of patients with the least treatment-related symptom burden. ..
  3. Pain and Symptoms of Cancer: Assessment and Treatment
    Charles Cleeland; Fiscal Year: 2007
    ....
  4. Mechanisms and Treatment of Cancer-Related Symptoms Conf
    Charles Cleeland; Fiscal Year: 2005
    ..The conference should also be of interest to pharmaceutical companies that are developing "pipeline" drugs for symptom control and supportive care. ..
  5. CANCER PAIN AND ITS MANAGEMENT
    Charles Cleeland; Fiscal Year: 2001
    ....
  6. Reducing the Symptom Burden Produced by Aggressive Cancer Therapies
    Charles S Cleeland; Fiscal Year: 2010
    ..The ultimate goal of this research is to be able to administer the best available curative therapy to the largest number of patients with the least treatment-related symptom burden. ..