FRANCOIS CLARET

Summary

Affiliation: The University of Texas
Country: USA

Publications

  1. doi request reprint Novel roles of reactive oxygen species in the pathogenesis of acute myeloid leukemia
    Fuling Zhou
    Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    J Leukoc Biol 94:423-9. 2013
  2. pmc Curcumin analogue T83 exhibits potent antitumor activity and induces radiosensitivity through inactivation of Jab1 in nasopharyngeal carcinoma
    Yunbao Pan
    Department of Pathophysiology, Zhongshan School of Medicine, Sun Yat Sen University, Guangzhou, Guangdong 510080, People s Republic of China
    BMC Cancer 13:323. 2013
  3. pmc JAB1/CSN5: a new player in cell cycle control and cancer
    Terry J Shackleford
    Department of Systems Biology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, Texas 77030, USA
    Cell Div 5:26. 2010
  4. pmc Stat3 and CCAAT/enhancer binding protein beta (C/EBP-beta) regulate Jab1/CSN5 expression in mammary carcinoma cells
    Terry J Shackleford
    Department of Systems Biology, University of Texas MD Anderson Cancer Center, Houston, 77030, USA
    Breast Cancer Res 13:R65. 2011

Research Grants

  1. Targeting JAB1 Oncogenic Function in Breast Cancer
    FRANCOIS CLARET; Fiscal Year: 2007
  2. Validation of new biomarker for human cancers
    FRANCOIS CLARET; Fiscal Year: 2006
  3. Molecular Mode of Action of JAB-1 in Cell Proliferation
    FRANCOIS CLARET; Fiscal Year: 2006
  4. Targeting JAB1 Oncogenic Function in Breast Cancer
    Francois X Claret; Fiscal Year: 2010

Collaborators

  • Xiao Feng Le
  • Terry J Shackleford
  • Fuling Zhou
  • Yunbao Pan
  • Qing Liu
  • Mengyao Wang
  • Sumei Wang
  • Bojin Su
  • Qiang Shen
  • Xianzhang Bu
  • Yinglin Zuo
  • Tao Xu
  • Chunhua Wang
  • Huiling Yang
  • Dujuan Wang
  • Anita L Korapati
  • Ling Tian
  • WARREN S LIAO
  • Qingxiu Zhang
  • Angela M Baumgartner
  • Thuy T Vu

Detail Information

Publications4

  1. doi request reprint Novel roles of reactive oxygen species in the pathogenesis of acute myeloid leukemia
    Fuling Zhou
    Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    J Leukoc Biol 94:423-9. 2013
    ..In this review, we summarize the recent findings that support a role for ROS in the pathogenesis of AML and outline innovative approaches in the implementation of redox therapies for myeloid malignancies. ..
  2. pmc Curcumin analogue T83 exhibits potent antitumor activity and induces radiosensitivity through inactivation of Jab1 in nasopharyngeal carcinoma
    Yunbao Pan
    Department of Pathophysiology, Zhongshan School of Medicine, Sun Yat Sen University, Guangzhou, Guangdong 510080, People s Republic of China
    BMC Cancer 13:323. 2013
    ..In this study, we explored the antitumor effect of a curcumin analogue T83 in NPC, and found T83 exhibits antitumor activity and induces radiosensitivity through inactivation of Jab1 in NPC...
  3. pmc JAB1/CSN5: a new player in cell cycle control and cancer
    Terry J Shackleford
    Department of Systems Biology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, Texas 77030, USA
    Cell Div 5:26. 2010
    ..Further, we also discuss the regulation of Jab1/CSN5 in cancers and its potential as a therapeutic target...
  4. pmc Stat3 and CCAAT/enhancer binding protein beta (C/EBP-beta) regulate Jab1/CSN5 expression in mammary carcinoma cells
    Terry J Shackleford
    Department of Systems Biology, University of Texas MD Anderson Cancer Center, Houston, 77030, USA
    Breast Cancer Res 13:R65. 2011
    ..The mechanism of Jab1 gene expression and its deregulation in cancer cells remains to be identified. We therefore investigated the transcriptional regulatory mechanisms of Jab1 expression in human breast carcinoma cells...

Research Grants10

  1. Targeting JAB1 Oncogenic Function in Breast Cancer
    FRANCOIS CLARET; Fiscal Year: 2007
    ..Upstream targets regulating JAB1 expression may be identified for use in future therapeutic paradigms. ..
  2. Validation of new biomarker for human cancers
    FRANCOIS CLARET; Fiscal Year: 2006
    ..Development of new prognosis/diagnostic markers for breast cancer and lymphoma would be invaluable. ..
  3. Molecular Mode of Action of JAB-1 in Cell Proliferation
    FRANCOIS CLARET; Fiscal Year: 2006
    ..Using JAB1 to re-establish a G1 checkpoint in tumor cells to block proliferation could represent a powerful therapeutic tool. ..
  4. Targeting JAB1 Oncogenic Function in Breast Cancer
    Francois X Claret; Fiscal Year: 2010
    ..Upstream targets regulating JAB1 expression may be identified for use in future therapeutic paradigms. ..