- Nicotinamide rescues human embryonic stem cell-derived neuroectoderm from parthanatic cell deathFlavio Cimadamore
Burnham Institute for Medical Research, La Jolla, California 92037, USA
Stem Cells 27:1772-81. 2009..We argue that small natural metabolites provide a powerful physiological tool to optimize hESC differentiation compatible with the requirements of regenerative medicine...
- Human ESC-derived neural crest model reveals a key role for SOX2 in sensory neurogenesisFlavio Cimadamore
Sanford Burnham Medical Research Institute, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA
Cell Stem Cell 8:538-51. 2011..We found that SOX2 binds directly to NGN1 and MASH1 promoters and is required for their expression. Our data suggest that SOX2 plays a key role for NGN1-dependent acquisition of neuronal fates in sensory ganglia...