Woonbok Chung

Summary

Affiliation: The University of Texas
Country: USA

Publications

  1. pmc Detection of bladder cancer using novel DNA methylation biomarkers in urine sediments
    Woonbok Chung
    Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Cancer Epidemiol Biomarkers Prev 20:1483-91. 2011
  2. pmc Identification of novel tumor markers in prostate, colon and breast cancer by unbiased methylation profiling
    Woonbok Chung
    Department of Leukemia, Baylor College of Medicine, Houston, Texas, United States of America
    PLoS ONE 3:e2079. 2008
  3. pmc DNA methylation profiles of primary colorectal carcinoma and matched liver metastasis
    Kazuo Konishi
    Department of Leukemia, Division of Cancer Medicine, The University of Texas M D Anderson Cancer Center, Houston, Texas, United States of America
    PLoS ONE 6:e27889. 2011
  4. pmc Mechanisms of resistance to decitabine in the myelodysplastic syndrome
    Taichun Qin
    Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
    PLoS ONE 6:e23372. 2011
  5. pmc Aberrant DNA methylation is associated with disease progression, resistance to imatinib and shortened survival in chronic myelogenous leukemia
    Jaroslav Jelinek
    Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
    PLoS ONE 6:e22110. 2011
  6. pmc Genome architecture marked by retrotransposons modulates predisposition to DNA methylation in cancer
    Marcos R H Estecio
    Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA
    Genome Res 20:1369-82. 2010
  7. pmc Sensitive and specific detection of early gastric cancer with DNA methylation analysis of gastric washes
    Yoshiyuki Watanabe
    Department of Leukemia, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Gastroenterology 136:2149-58. 2009
  8. pmc Frequent alteration of MLL3 frameshift mutations in microsatellite deficient colorectal cancer
    Yoshiyuki Watanabe
    Department of Leukemia, The University of Texas M D Anderson Cancer Center, Houston, Texas, United States of America
    PLoS ONE 6:e23320. 2011
  9. ncbi request reprint Age-related DNA methylation changes in normal human prostate tissues
    Bernard Kwabi-Addo
    Department of Pathology, Baylor College of Medicine, The University of Texas M D Anderson Cancer Center, Houston, Texas, USA
    Clin Cancer Res 13:3796-802. 2007
  10. pmc Aberrant CpG island methylation in acute myeloid leukemia is accentuated at relapse
    Heike Kroeger
    Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Blood 112:1366-73. 2008

Collaborators

Detail Information

Publications12

  1. pmc Detection of bladder cancer using novel DNA methylation biomarkers in urine sediments
    Woonbok Chung
    Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Cancer Epidemiol Biomarkers Prev 20:1483-91. 2011
    ..Bladder cancer (BCa) remains a lethal malignancy that can be cured if detected early. DNA hypermethylation is a common epigenetic abnormality in cancer that may serve as a marker of disease activity...
  2. pmc Identification of novel tumor markers in prostate, colon and breast cancer by unbiased methylation profiling
    Woonbok Chung
    Department of Leukemia, Baylor College of Medicine, Houston, Texas, United States of America
    PLoS ONE 3:e2079. 2008
    ..Our data identify new targets of transcriptional silencing in cancer, and provide new biomarkers that could be useful in screening for prostate cancer and other cancers...
  3. pmc DNA methylation profiles of primary colorectal carcinoma and matched liver metastasis
    Kazuo Konishi
    Department of Leukemia, Division of Cancer Medicine, The University of Texas M D Anderson Cancer Center, Houston, Texas, United States of America
    PLoS ONE 6:e27889. 2011
    ..The contribution of DNA methylation to the metastatic process in colorectal cancers (CRCs) is unclear...
  4. pmc Mechanisms of resistance to decitabine in the myelodysplastic syndrome
    Taichun Qin
    Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
    PLoS ONE 6:e23372. 2011
    ..Therefore, we investigated mechanisms of primary and secondary resistance to DAC in MDS...
  5. pmc Aberrant DNA methylation is associated with disease progression, resistance to imatinib and shortened survival in chronic myelogenous leukemia
    Jaroslav Jelinek
    Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
    PLoS ONE 6:e22110. 2011
    ..Finally, DNA methylation of PDLIM4 may help identify a subset of CML patients that would benefit from treatment with Src/Abl inhibitors...
  6. pmc Genome architecture marked by retrotransposons modulates predisposition to DNA methylation in cancer
    Marcos R H Estecio
    Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA
    Genome Res 20:1369-82. 2010
    ....
  7. pmc Sensitive and specific detection of early gastric cancer with DNA methylation analysis of gastric washes
    Yoshiyuki Watanabe
    Department of Leukemia, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Gastroenterology 136:2149-58. 2009
    ..We hypothesized that methylation analysis of DNA recovered from gastric washes could be used to detect gastric cancer...
  8. pmc Frequent alteration of MLL3 frameshift mutations in microsatellite deficient colorectal cancer
    Yoshiyuki Watanabe
    Department of Leukemia, The University of Texas M D Anderson Cancer Center, Houston, Texas, United States of America
    PLoS ONE 6:e23320. 2011
    ..Mutations in MLL3 were found in a whole genome analysis of colorectal cancer but have not been confirmed by a separate study...
  9. ncbi request reprint Age-related DNA methylation changes in normal human prostate tissues
    Bernard Kwabi-Addo
    Department of Pathology, Baylor College of Medicine, The University of Texas M D Anderson Cancer Center, Houston, Texas, USA
    Clin Cancer Res 13:3796-802. 2007
    ..We examined the extent of gene methylation in pathologically normal human prostate as a function of age...
  10. pmc Aberrant CpG island methylation in acute myeloid leukemia is accentuated at relapse
    Heike Kroeger
    Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Blood 112:1366-73. 2008
    ..0% to 15.2% (median 10.6%) genes in relapse (P < .001). Our data suggest that DNA methylation is involved in AML progression and provide a rationale for the use of epigenetic agents in remission maintenance...
  11. ncbi request reprint Tumor-associated methylation of the putative tumor suppressor AJAP1 gene and association between decreased AJAP1 expression and shorter survival in patients with glioma
    David Cogdell
    Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA
    Chin J Cancer 30:247-53. 2011
    ..Thus, both genetic (gene deletion) and epigenetic alterations (promoter methylation) are likely mechanisms that inactivate the putative tumor suppressor AJAP1 in gliomas, which contributes to poor prognosis...
  12. ncbi request reprint Silencing of bidirectional promoters by DNA methylation in tumorigenesis
    Jingmin Shu
    Department of Leukemia, M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer Res 66:5077-84. 2006
    ....