Wong Ho Chow

Summary

Affiliation: The University of Texas
Country: USA

Publications

  1. pmc Racial disparity in renal cell carcinoma patient survival according to demographic and clinical characteristics
    Wong Ho Chow
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA
    Cancer 119:388-94. 2013
  2. ncbi request reprint Population attributable risks of esophageal and gastric cancers
    Lawrence S Engel
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA
    J Natl Cancer Inst 95:1404-13. 2003
  3. ncbi request reprint Occupation and risk of esophageal and gastric cardia adenocarcinoma
    Lawrence S Engel
    Occupational Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
    Am J Ind Med 42:11-22. 2002
  4. ncbi request reprint Commuting physical activity and risk of colon cancer in Shanghai, China
    Lifang Hou
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892 7240, USA
    Am J Epidemiol 160:860-7. 2004
  5. pmc The importance of exposure rate on odds ratios by cigarette smoking and alcohol consumption for esophageal adenocarcinoma and squamous cell carcinoma in the Barrett's Esophagus and Esophageal Adenocarcinoma Consortium
    Jay H Lubin
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH DHHS, Bethesda, MD 20892, USA
    Cancer Epidemiol 36:306-16. 2012
  6. ncbi request reprint Occupation and adult-onset asthma among Chinese women in a population-based cohort
    Srmena Krstev
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, Maryland 20892, USA
    Am J Ind Med 50:265-73. 2007
  7. pmc Apolipoprotein E/C1 locus variants modify renal cell carcinoma risk
    Lee E Moore
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20852, USA
    Cancer Res 69:8001-8. 2009
  8. ncbi request reprint Genetic polymorphisms in folate metabolism and the risk of stomach cancer
    Fang Fang Zhang
    Division of Cancer Epidemiology and Genetics, Advanced Technology Center, National Cancer Institute, Gaithersburg, Maryland, USA
    Cancer Epidemiol Biomarkers Prev 16:115-21. 2007
  9. pmc Serum leptin and adiponectin levels and risk of renal cell carcinoma
    Linda M Liao
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA
    Obesity (Silver Spring) 21:1478-85. 2013
  10. ncbi request reprint Interleukin-8 polymorphisms are not associated with gastric cancer risk in a Polish population
    Sharon A Savage
    Section of Genomic Variation, Pediatric Oncology Branch, National Cancer Institute, Advanced Technology Center, 8717 Grovemont Circle, Bethesda, MD 20892 4605, USA
    Cancer Epidemiol Biomarkers Prev 15:589-91. 2006

Collaborators

Detail Information

Publications76

  1. pmc Racial disparity in renal cell carcinoma patient survival according to demographic and clinical characteristics
    Wong Ho Chow
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA
    Cancer 119:388-94. 2013
    ..This study examined whether the racial disparity in RCC patient survival varies by demographic and clinical characteristics...
  2. ncbi request reprint Population attributable risks of esophageal and gastric cancers
    Lawrence S Engel
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA
    J Natl Cancer Inst 95:1404-13. 2003
    ..Herein, we estimate the population attributable risks (PARs) for various risk factors observed in a multicenter population-based case-control study...
  3. ncbi request reprint Occupation and risk of esophageal and gastric cardia adenocarcinoma
    Lawrence S Engel
    Occupational Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
    Am J Ind Med 42:11-22. 2002
    ..Adenocarcinomas of the esophagus and gastric cardia have risen dramatically in incidence over the past few decades, however, little research has been conducted on the occupational risk factors for these cancers...
  4. ncbi request reprint Commuting physical activity and risk of colon cancer in Shanghai, China
    Lifang Hou
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892 7240, USA
    Am J Epidemiol 160:860-7. 2004
    ..54 for men; OR = 7.42, 95% CI: 2.84, 10.01 for women). Our results suggest that regular and frequent physical activity over a long period of time protects from colon cancer and significantly modifies the body mass index-associated risk...
  5. pmc The importance of exposure rate on odds ratios by cigarette smoking and alcohol consumption for esophageal adenocarcinoma and squamous cell carcinoma in the Barrett's Esophagus and Esophageal Adenocarcinoma Consortium
    Jay H Lubin
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH DHHS, Bethesda, MD 20892, USA
    Cancer Epidemiol 36:306-16. 2012
    ..e., the impact on the OR for a fixed total exposure of high exposure rate for short duration compared with low exposure rate for long duration...
  6. ncbi request reprint Occupation and adult-onset asthma among Chinese women in a population-based cohort
    Srmena Krstev
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, Maryland 20892, USA
    Am J Ind Med 50:265-73. 2007
    ..We examined the associations between occupation and asthma among women in a case-control study nested in the population-based Shanghai Women's Health Study cohort in China...
  7. pmc Apolipoprotein E/C1 locus variants modify renal cell carcinoma risk
    Lee E Moore
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20852, USA
    Cancer Res 69:8001-8. 2009
    ..In two large case-control studies, our findings further define a functional region of interest at the APOE locus that increases RCC susceptibility...
  8. ncbi request reprint Genetic polymorphisms in folate metabolism and the risk of stomach cancer
    Fang Fang Zhang
    Division of Cancer Epidemiology and Genetics, Advanced Technology Center, National Cancer Institute, Gaithersburg, Maryland, USA
    Cancer Epidemiol Biomarkers Prev 16:115-21. 2007
    ..Our study did not identify strong genetic determinants in the folate metabolism pathway for stomach cancer risk...
  9. pmc Serum leptin and adiponectin levels and risk of renal cell carcinoma
    Linda M Liao
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA
    Obesity (Silver Spring) 21:1478-85. 2013
    ..Adipokines, such as leptin and adiponectin, may link obesity and cancer, with different quantitative effects by race...
  10. ncbi request reprint Interleukin-8 polymorphisms are not associated with gastric cancer risk in a Polish population
    Sharon A Savage
    Section of Genomic Variation, Pediatric Oncology Branch, National Cancer Institute, Advanced Technology Center, 8717 Grovemont Circle, Bethesda, MD 20892 4605, USA
    Cancer Epidemiol Biomarkers Prev 15:589-91. 2006
  11. pmc Variants in blood pressure genes and the risk of renal cell carcinoma
    Gabriella Andreotti
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20852 4906, USA
    Carcinogenesis 31:614-20. 2010
    ..003). Our findings suggest that common genetic variants of AGT, particularly those in the promoter, increase RCC risk among subjects who are hypertensive or overweight...
  12. pmc Occupational trichloroethylene exposure and renal carcinoma risk: evidence of genetic susceptibility by reductive metabolism gene variants
    Lee E Moore
    Division of Cancer Epidemiology and Genetics, NIH, National Cancer Institute, NIH, Bethesda, Maryland 20852, USA
    Cancer Res 70:6527-36. 2010
    ....
  13. pmc Renal cancer risk and occupational exposure to polycyclic aromatic hydrocarbons and plastics
    Sara Karami
    National Cancer Institute, Division of Cancer Epidemiology and Genetics, Occupational and Environmental Epidemiology Branch, 6120 Executive Blvd, EPS 8121, Rockville, MD 20852, USA
    J Occup Environ Med 53:218-23. 2011
    ..To investigate whether occupational exposure to polycyclic aromatic hydrocarbons and certain plastic monomers increased renal cell carcinoma (RCC) risk...
  14. pmc Hypertension and risk of renal cell carcinoma among white and black Americans
    Joanne S Colt
    Division of Cancer Epidemiology and Genetics, Occupational and Environmental Epidemiology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 7240, USA
    Epidemiology 22:797-804. 2011
    ..We investigated the hypertension-renal cancer association by race, and we assessed the role of hypertension in the racial disparity of renal cancer incidence...
  15. ncbi request reprint Ginseng intake and gastric cancer risk in the Shanghai Women's Health Study cohort
    Farin Kamangar
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, Room 3034, Bethesda, MD 20892 7232, USA
    Cancer Epidemiol Biomarkers Prev 16:629-30. 2007
  16. ncbi request reprint No apparent association between NAT1 and NAT2 genotypes and risk of stomach cancer
    Qing Lan
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Bethesda, Maryland 20892 7240, USA
    Cancer Epidemiol Biomarkers Prev 12:384-6. 2003
  17. pmc Nonsteroidal anti-inflammatory drug use reduces risk of adenocarcinomas of the esophagus and esophagogastric junction in a pooled analysis
    Linda M Liao
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20852, USA
    Gastroenterology 142:442-452.e5; quiz e22-3. 2012
    ..However, individual studies have been too small to accurately assess the effects of medication type, frequency, or duration of use. We performed a pooled analysis to investigate these associations...
  18. pmc A shared susceptibility locus in PLCE1 at 10q23 for gastric adenocarcinoma and esophageal squamous cell carcinoma
    Christian C Abnet
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA
    Nat Genet 42:764-7. 2010
    ..19 x 10(-15); OR = 1.57), and for those in the noncardia stomach it was absent (P = 0.44; OR = 1.05). Our findings at 10q23 could provide insight into the high incidence of both cancers in China...
  19. pmc Urinary prostaglandin E2 metabolite and gastric cancer risk in the Shanghai women's health study
    Linda M Dong
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892, USA
    Cancer Epidemiol Biomarkers Prev 18:3075-8. 2009
    ..pylori status, and for cases diagnosed within 46 months after study enrollment. Our findings suggest that higher levels of urinary PGE-M, a marker of inflammation, may be associated with gastric cancer risk...
  20. pmc Occupation and chronic bronchitis among Chinese women
    Srmena Krstev
    Occupational and Environmental Epidemiology Branch, National Cancer Institute, National Institutes of Health DHHS, 6120 Executive Boulevard, Bethesda, MD 20892, USA
    J Occup Environ Med 50:64-71. 2008
    ..To examine the association between occupation and chronic bronchitis among a cross section of Chinese women who participated in the Shanghai Women's Health Study...
  21. pmc Reproductive factors and kidney cancer risk in 2 US cohort studies, 1993-2010
    Sara Karami
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA
    Am J Epidemiol 177:1368-77. 2013
    ..Our results suggest that hysterectomy is associated with increased risk of kidney cancer. The observed associations with age at menarche and oral contraceptive use warrant further investigation...
  22. pmc A case-control study of occupation/industry and renal cell carcinoma risk
    Sara Karami
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, 6120 Executive Boulevard, MSC 7242, Bethesda, MD 20892 7242, USA
    BMC Cancer 12:344. 2012
    ..Here, we investigated associations between employment in specific occupations and industries and RCC, and its most common histologic subtype, clear cell RCC (ccRCC)...
  23. pmc Occupational sunlight exposure and risk of renal cell carcinoma
    Sara Karami
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, USA
    Cancer 116:2001-10. 2010
    ....
  24. pmc A case-control study of reproductive factors and renal cell carcinoma among black and white women in the United States
    Mark P Purdue
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health DHHS, 6120 Executive Boulevard, Bethesda, MD 20892 7240, USA
    Cancer Causes Control 22:1537-44. 2011
    ..We investigated whether reproductive factors are associated with RCC, overall and by race, within a population-based case-control study...
  25. pmc Cigarette smoking increases risk of Barrett's esophagus: an analysis of the Barrett's and Esophageal Adenocarcinoma Consortium
    Michael B Cook
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20852 7234, USA
    Gastroenterology 142:744-53. 2012
    ..We investigated whether tobacco smoking and other factors increase risk for Barrett's esophagus...
  26. pmc Epidemiology and risk factors for kidney cancer
    Wong Ho Chow
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Department of Health and Human Services, Bethesda, MD 20892 7240, USA
    Nat Rev Urol 7:245-57. 2010
    ..Large consortium efforts employing genome-wide scanning technology are underway, which hold promise for novel discoveries in renal carcinogenesis...
  27. pmc Von Hippel-Lindau (VHL) inactivation in sporadic clear cell renal cancer: associations with germline VHL polymorphisms and etiologic risk factors
    Lee E Moore
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America
    PLoS Genet 7:e1002312. 2011
    ..A proportion of tumors from current smokers lacked VHL alterations and may represent a biologically distinct clinical entity from inactivated cases...
  28. pmc Dietary nitrate and nitrite intake and risk of colorectal cancer in the Shanghai Women's Health Study
    Curt T Dellavalle
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD
    Int J Cancer 134:2917-26. 2014
    ..Our findings suggest that high dietary nitrate intake among subgroups expected to have higher exposure to endogenously formed NOCs increases risk of colorectal cancer. ..
  29. ncbi request reprint Selected DNA repair polymorphisms and gastric cancer in Poland
    Wen Yi Huang
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
    Carcinogenesis 26:1354-9. 2005
    ..These results need replication in larger epidemiological studies of gastric cancer...
  30. pmc Analysis of SNPs and haplotypes in vitamin D pathway genes and renal cancer risk
    Sara Karami
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health NIH, Department of Health and Human Services DHHS, Bethesda, Maryland, USA
    PLoS ONE 4:e7013. 2009
    ..This study comprehensively evaluated genetic variation across eight vitamin D pathway genes in relation to RCC risk. We found increased risk associated with VDR and RXRA. Replication studies are warranted to confirm these findings...
  31. pmc Intake of fiber and fiber-rich plant foods is associated with a lower risk of renal cell carcinoma in a large US cohort
    Carrie R Daniel
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA
    Am J Clin Nutr 97:1036-43. 2013
    ..Diet may play a role in the etiology of RCC directly and/or indirectly...
  32. pmc Comprehensive analysis of 5-aminolevulinic acid dehydrogenase (ALAD) variants and renal cell carcinoma risk among individuals exposed to lead
    Dana M Van Bemmel
    Cancer Prevention Fellowship Program, Office of the Director, National Cancer Institute, Bethesda, Maryland, United States of America
    PLoS ONE 6:e20432. 2011
    ..Epidemiologic studies are reporting associations between lead exposure and human cancers. A polymorphism in the 5-aminolevulinic acid dehydratase (ALAD) gene affects lead toxicokinetics and may modify the adverse effects of lead...
  33. pmc Accelerometer-measured physical activity in Chinese adults
    Tricia M Peters
    National Cancer Institute, Bethesda, Maryland, USA
    Am J Prev Med 38:583-91. 2010
    ..Following adoption of a Western lifestyle, China is experiencing a decline in physical activity levels, which is projected to contribute to future increases in the burden of chronic diseases...
  34. pmc Occupation and breast cancer risk among Shanghai women in a population-based cohort study
    Bu Tian Ji
    National Cancer Institute, NIH, DHHS, Bethesda, Maryland 20852, USA
    Am J Ind Med 51:100-10. 2008
    ..A total of 74,942 female subjects were recruited in a population-based cohort study in Shanghai, China between 1997 and 2000. We examined the relationship between occupation and breast cancer risk...
  35. pmc A prospective study of leukocyte telomere length and risk of renal cell carcinoma
    Jonathan N Hofmann
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, EPS 8113, Bethesda, MD 20892, USA
    Cancer Epidemiol Biomarkers Prev 22:997-1000. 2013
    ..There is some evidence from case-control studies suggesting that short leukocyte telomere length may be associated with an increased risk of renal cell carcinoma (RCC); however, this association has not been investigated prospectively...
  36. pmc Physical activity during adulthood and adolescence in relation to renal cell cancer
    Steven C Moore
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA
    Am J Epidemiol 168:149-57. 2008
    ..82 (95% CI: 0.68, 1.00; p(trend) = 0.05) for activity during adolescence. The authors conclude that increased physical activity, including activity during adolescence, is associated with reduced risk of renal cell cancer...
  37. pmc The association between chronic renal failure and renal cell carcinoma may differ between black and white Americans
    Jonathan N Hofmann
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, Bethesda, MD 20892 7240, USA
    Cancer Causes Control 24:167-74. 2013
    ..Risk of RCC is elevated among end-stage renal disease patients, although no studies have looked at differences by race in the relationship between chronic renal failure and RCC...
  38. pmc The chromosome 2p21 region harbors a complex genetic architecture for association with risk for renal cell carcinoma
    Summer S Han
    Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 7231, USA
    Hum Mol Genet 21:1190-200. 2012
    ..72 × 10(-9), per-allele OR = 1.28, 95% CI: 1.18-1.39) In conclusion, we report that chromosome 2p21 harbors a complex genetic architecture for common RCC risk variants...
  39. pmc Systemic cytokine levels and subsequent risk of gastric cancer in Chinese Women
    Hui Lee Wong
    US Food and Drug Administration, Silver Spring, Maryland, USA
    Cancer Sci 102:1911-5. 2011
    ..Systemic plasma IL-6 levels may inform long-term gastric cancer risk. This novel finding awaits confirmation in future studies with sequential plasma collection...
  40. pmc Alcohol intake and risk of oesophageal adenocarcinoma: a pooled analysis from the BEACON Consortium
    Neal D Freedman
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, Rockville, MD 20852, USA
    Gut 60:1029-37. 2011
    ..Therefore, the association of alcohol intake with OSCC, OA, and OGJA was determined in nine case-control studies and two cohort studies of the Barrett's Esophagus and Esophageal Adenocarcinoma Consortium (BEACON)...
  41. pmc LINE-1 methylation levels in leukocyte DNA and risk of renal cell cancer
    Linda M Liao
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, United States of America
    PLoS ONE 6:e27361. 2011
    ..In this study, we aimed to examine the association between long interspersed nuclear elements (LINE-1) methylation levels, as a biomarker of global DNA methylation in blood cell DNA, and renal cell cancer risk...
  42. pmc Night-shift work and breast cancer risk in a cohort of Chinese women
    Anjoeka Pronk
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, EPS 8111, MSC 7240, Bethesda, MD 20892, USA
    Am J Epidemiol 171:953-9. 2010
    ..There were no indications of effect modification. The lack of an association between night-shift work and breast cancer adds to the inconsistent epidemiologic evidence. It may be premature to consider shift work a cause of cancer...
  43. pmc Body mass index and colon cancer risk in Chinese people: menopause as an effect modifier
    Lifang Hou
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, 6120 Executive Blvd EPS Suite 511, MSC 7240, Bethesda, MD 20892 7240, USA
    Eur J Cancer 42:84-90. 2006
    ..91) and 0.7 (95% CI 0.5-0.95), respectively. Our findings suggest that BMI predicts colon cancer risk in both genders. Among women, however, the risk is modified by menopause status, possibly through altered endogenous oestrogen levels...
  44. doi request reprint Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia
    Qing Lan
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA
    Nat Genet 44:1330-5. 2012
    ..3. We observed no evidence of association for lung cancer at 15q25 in never-smoking women in Asia, providing strong evidence that this locus is not associated with lung cancer independent of smoking...
  45. pmc An investigation of risk factors for renal cell carcinoma by histologic subtype in two case-control studies
    Mark P Purdue
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA
    Int J Cancer 132:2640-7. 2013
    ..Our findings support the existence of distinct age, sex and racial distributions for RCC subtypes, and suggest that the obesity-RCC association differs by histology...
  46. pmc Genotypic variants at 2q33 and risk of esophageal squamous cell carcinoma in China: a meta-analysis of genome-wide association studies
    Christian C Abnet
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 7236, USA
    Hum Mol Genet 21:2132-41. 2012
    ..Future studies of esophageal and other cancers should focus on comprehensive sequencing of this 2q33 locus and functional analysis of rs13016963 and rs10201587 and other strongly correlated variants...
  47. pmc Family cancer history affecting risk of colorectal cancer in a prospective cohort of Chinese women
    Gwen Murphy
    Cancer Prevention Fellowship Program, Office of Preventive Oncology, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD, USA
    Cancer Causes Control 20:1517-21. 2009
    ..Our cohort results suggest that consistent with findings from Western populations, having a family history of colorectal cancer may influence colorectal cancer risk to a similar extent in a low-risk population...
  48. pmc Contemporary epidemiology of renal cell cancer
    Wong Ho Chow
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892 7240, USA
    Cancer J 14:288-301. 2008
    ..Few epidemiologic studies have evaluated risk factors by subtypes of renal cell cancer defined by somatic mutations and other tumor markers...
  49. pmc A nested case-control study of leukocyte mitochondrial DNA copy number and renal cell carcinoma in the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial
    Jonathan N Hofmann
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA
    Carcinogenesis 35:1028-31. 2014
    ..3). Results of this study suggest that high pre-diagnostic leukocyte mtDNA copy number, a suspected marker of oxidative DNA damage and mitochondrial dysfunction, is associated with increased future RCC risk. ..
  50. pmc Polycyclic aromatic hydrocarbons: determinants of urinary 1-hydroxypyrene glucuronide concentration and risk of colorectal cancer in the Shanghai Women's Health Study
    Jonathan N Hofmann
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA
    BMC Cancer 13:282. 2013
    ....
  51. pmc GST, NAT1, CYP1A1 polymorphisms and risk of esophageal and gastric adenocarcinomas
    Louise Wideroff
    Applied Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, EPN 4005, 6130 Executive Boulevard, MSC 7344, Bethesda, MD 20892 7344, USA
    Cancer Detect Prev 31:233-6. 2007
    ..In a population-based case-control study, we examined risks in relation to polymorphisms of the following genes: GSTP1; GSTM1; GSTT1; NAT1; and CYP1A1...
  52. pmc Menstrual and reproductive factors and gastric cancer risk in a large prospective study of women
    Neal D Freedman
    Cancer Prevention Fellowship Program, Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA
    Gut 56:1671-7. 2007
    ..Gastric cancer incidence rates are consistently lower in women than men in both high and low-risk regions worldwide. Sex hormones, such as progesterone and estrogen, may protect women against gastric cancer...
  53. pmc Longer telomere length in peripheral white blood cells is associated with risk of lung cancer and the rs2736100 (CLPTM1L-TERT) polymorphism in a prospective cohort study among women in China
    Qing Lan
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD, USA
    PLoS ONE 8:e59230. 2013
    ..030). Our findings suggest that individuals with longer telomere length in peripheral white blood cells may have an increased risk of lung cancer, but require replication in additional prospective cohorts and populations...
  54. ncbi request reprint Obesity and cancer risk among white and black United States veterans
    Claudine Samanic
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, 6120 Executive Boulevard, Room 8115, Bethesda, MD 20892, USA
    Cancer Causes Control 15:35-43. 2004
    ..Obesity has been linked to excess risk for many cancers, but the evidence remains tenuous for some types. Although the prevalence of obesity varies by race, few studies of obesity-related cancer risk have included non-white subjects...
  55. doi request reprint Nightshift work job exposure matrices and urinary 6-sulfatoxymelatonin levels among healthy Chinese women
    Bu Tian Ji
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA
    Scand J Work Environ Health 38:553-9. 2012
    ..We examined the association between aMT6s levels and shift work estimated by a job exposure matrix (JEM) among healthy participants of the Shanghai Women's Health Study...
  56. pmc Validity of a physical activity questionnaire in Shanghai
    Tricia M Peters
    National Cancer Institute, Division of Cancer Epidemiology and Genetics, Bethesda, MD, USA
    Med Sci Sports Exerc 42:2222-30. 2010
    ..Because available PAQ may not capture the full range of PA in which urban Chinese adults engage, a PAQ was developed for this purpose. We examined the validity of this PAQ and the 1-yr stability of PA in 545 urban Shanghai adults...
  57. pmc Circulating 25-hydroxyvitamin D and risk of esophageal and gastric cancer: Cohort Consortium Vitamin D Pooling Project of Rarer Cancers
    Christian C Abnet
    National Cancer Institute, Bethesda, Maryland 20852, USA
    Am J Epidemiol 172:94-106. 2010
    ..31, 0.96). Subgroup analyses by alcohol consumption produced opposing trends. Results do not support the hypothesis that interventions aimed at increasing vitamin D status would lead to a lower risk of these highly fatal cancers...
  58. pmc Mitochondrial DNA copy number and risk of gastric cancer: a report from the Shanghai Women's Health Study
    Linda M Liao
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, EPS 8003, MSC 7240, Bethesda, MD 20892, USA
    Cancer Epidemiol Biomarkers Prev 20:1944-9. 2011
    ..mtDNA copy number in leukocyte DNA has also been linked to several other cancers, although the temporal relationship between mtDNA and cancer has not been adequately explored...
  59. ncbi request reprint Genetic polymorphisms in heterocyclic amine metabolism and risk of colorectal adenomas
    Naoko Ishibe
    Genetic Epidemioly Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, Maryland 20892, USA
    Pharmacogenetics 12:145-50. 2002
    ..Further study of larger populations is needed to confirm and extend these observations...
  60. pmc Combining a job-exposure matrix with exposure measurements to assess occupational exposure to benzene in a population cohort in shanghai, china
    Melissa C Friesen
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA
    Ann Occup Hyg 56:80-91. 2012
    ..Our aim was to better discriminate between job, industry, and time differences in exposure levels compared to using a JEM alone...
  61. doi request reprint Pathologic validation of renal cell carcinoma histology in the Surveillance, Epidemiology, and End Results program
    Brian Shuch
    Urologic Oncology Branch, National Cancer Institute, Bethesda, Md Electronic address
    Urol Oncol 32:23.e9-13. 2014
    ..The Surveillance, Epidemiology, and End Results (SEER) program is an important epidemiologic research tool to study cancer. No information is available on its pathologic accuracy for renal cell carcinoma (RCC)...
  62. pmc A case-control study of peripheral blood mitochondrial DNA copy number and risk of renal cell carcinoma
    Mark P Purdue
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, United States of America
    PLoS ONE 7:e43149. 2012
    ..In an attempt to replicate that finding, we measured mtDNA copy number in peripheral blood DNA from a U.S. population-based case-control study of RCC...
  63. ncbi request reprint Folate metabolism genes, vegetable intake and renal cancer risk in central Europe
    Lee E Moore
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD, USA
    Int J Cancer 122:1710-5. 2008
    ..04 for all). In summary, these findings suggest that common variation in MTHFR and TYMS genes may be associated with RCC risk, particularly when vegetable intake is low...
  64. pmc Cigarette smoking and adenocarcinomas of the esophagus and esophagogastric junction: a pooled analysis from the international BEACON consortium
    Michael B Cook
    Hormonal and Reproductive Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health DHHS, 6120 Executive Blvd, Bethesda, MD 20852 7234, USA
    J Natl Cancer Inst 102:1344-53. 2010
    ....
  65. pmc Large prospective investigation of meat intake, related mutagens, and risk of renal cell carcinoma
    Carrie R Daniel
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Rockville, MD, USA
    Am J Clin Nutr 95:155-62. 2012
    ..The evidence for meat intake and renal cell carcinoma (RCC) risk is inconsistent. Mutagens related to meat cooking and processing, and variation by RCC subtype may be important to consider...
  66. ncbi request reprint Tobacco smoking and colorectal hyperplastic and adenomatous polyps
    Bu Tian Ji
    National Cancer Institute, 6120 Executive Boulevard, EPS 8120, Bethesda, MD 20852, USA
    Cancer Epidemiol Biomarkers Prev 15:897-901. 2006
    ..In conclusion, tobacco use, particularly recent use, increases risk for both adenomatous and hyperplastic polyps, but the risks are substantially greater for hyperplastic lesions...
  67. pmc Prediagnostic circulating adipokine concentrations and risk of renal cell carcinoma in male smokers
    Linda M Liao
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA
    Carcinogenesis 34:109-12. 2013
    ..These findings provide the strongest evidence to date, suggesting that the association between obesity and RCC is mediated at least in part through the effects of low adiponectin...
  68. pmc Comprehensive evaluation of one-carbon metabolism pathway gene variants and renal cell cancer risk
    Todd M Gibson
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, United States of America
    PLoS ONE 6:e26165. 2011
    ..Variation in one-carbon metabolism genes, particularly MTHFR, has been associated with risk of a number of cancers in epidemiologic studies, but little is known regarding renal cancer...
  69. pmc Body mass index, effect modifiers, and risk of pancreatic cancer: a pooled study of seven prospective cohorts
    Li Jiao
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
    Cancer Causes Control 21:1305-14. 2010
    ..To investigate whether the positive association of body mass index (BMI, kg/m(2)) with risk of pancreatic cancer is modified by age, sex, smoking status, physical activity, and history of diabetes...
  70. pmc Risk of kidney cancer and chronic kidney disease in relation to hepatitis C virus infection: a nationwide register-based cohort study in Sweden
    Jonathan N Hofmann
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892, USA
    Eur J Cancer Prev 20:326-30. 2011
    ..Given inconsistent findings in the literature, it is premature to consider HCV infection to be a risk factor for kidney cancer...
  71. pmc Polymorphisms in estrogen- and androgen-metabolizing genes and the risk of gastric cancer
    Neal D Freedman
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Rockville, MD 20852, USA
    Carcinogenesis 30:71-7. 2009
    ..These findings should be interpreted cautiously until replicated in other studies...
  72. ncbi request reprint Relation of body mass index to cancer risk in 362,552 Swedish men
    Claudine Samanic
    Department of Health and Human Services, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, 6120 Executive Blvd, Room 8115, Bethesda, MD 20892, USA
    Cancer Causes Control 17:901-9. 2006
    ..For other cancer sites, the relationship with obesity is less well quantified, and the effect of weight change on cancer risk is unclear...
  73. pmc Metabolomics in epidemiology: sources of variability in metabolite measurements and implications
    Joshua N Sampson
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, Rockville, MD 20852, USA
    Cancer Epidemiol Biomarkers Prev 22:631-40. 2013
    ..Here, the authors assess the variability of a large subset of metabolites and evaluate the implications for epidemiologic studies...
  74. pmc Genetic variant in TP63 on locus 3q28 is associated with risk of lung adenocarcinoma among never-smoking females in Asia
    H Dean Hosgood
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, EPS 8118, MCS 7240, Bethesda, MD 20892 7240, USA
    Hum Genet 131:1197-203. 2012
    ..037; allelic risk = 0.82, 95% CI = 0.67-0.99). Our findings provide strong evidence that genetic variation in TP63 is associated with the risk of lung adenocarcinoma among Asian females in the absence of tobacco smoking...
  75. pmc A prospective analysis of prolonged sitting time and risk of renal cell carcinoma among 300,000 older adults
    Stephanie M George
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA
    Ann Epidemiol 21:787-90. 2011
    ..The authors prospectively examined the relationship of prolonged sitting and risk of RCC among 289,512 women and men in the National Institutes of Health-AARP Diet and Health Study...
  76. pmc Detectable clonal mosaicism and its relationship to aging and cancer
    Kevin B Jacobs
    Division of Cancer Epidemiology and Genetics, National Cancer Institute NCI, Rockville, Maryland, USA
    Nat Genet 44:651-8. 2012
    ..4; P = 3.8 × 10(-11)). These findings underscore the time-dependent nature of somatic events in the etiology of cancer and potentially other late-onset diseases...