EDUARDO CHICHILNISKY

Summary

Affiliation: The Salk Institute
Country: USA

Publications

  1. ncbi request reprint Information processing in the primate retina: circuitry and coding
    G D Field
    The Salk Institute, La Jolla, California 92037, USA
    Annu Rev Neurosci 30:1-30. 2007
  2. ncbi request reprint Detection sensitivity and temporal resolution of visual signals near absolute threshold in the salamander retina
    E J Chichilnisky
    Systems Neurobiology Laboratory, The Salk Institute, La Jolla, California 92037, USA
    J Neurosci 25:318-30. 2005
  3. ncbi request reprint Temporal resolution of ensemble visual motion signals in primate retina
    E J Chichilnisky
    Systems Neurobiology, The Salk Institute and University of California, San Diego, La Jolla, California 92037, USA
    J Neurosci 23:6681-9. 2003
  4. ncbi request reprint Functional asymmetries in ON and OFF ganglion cells of primate retina
    E J Chichilnisky
    Systems Neurobiology, The Salk Institute, La Jolla, California 92037, USA
    J Neurosci 22:2737-47. 2002
  5. ncbi request reprint A simple white noise analysis of neuronal light responses
    E J Chichilnisky
    Systems Neurobiology, The Salk Institute, La Jolla, CA 92037 1099, USA
    Network 12:199-213. 2001
  6. ncbi request reprint Trichromatic opponent color classification
    E J Chichilnisky
    Department of Psychology, Stanford University, CA 94305, USA
    Vision Res 39:3444-58. 1999
  7. ncbi request reprint Receptive-field microstructure of blue-yellow ganglion cells in primate retina
    E J Chichilnisky
    Department of Neurobiology, Stanford University, School of Medicine, Stanford, California 94305, USA
    Nat Neurosci 2:889-93. 1999
  8. ncbi request reprint Adaptation to temporal contrast in primate and salamander retina
    D Chander
    Systems Neurobiology, The Salk Institute, La Jolla, California 92037-1099, USA
    J Neurosci 21:9904-16. 2001
  9. ncbi request reprint Fidelity of the ensemble code for visual motion in primate retina
    E S Frechette
    The Salk Institute and University of California, San Diego, USA
    J Neurophysiol 94:119-35. 2005
  10. pmc Functional connectivity in the retina at the resolution of photoreceptors
    Greg D Field
    Systems Neurobiology Laboratories, Salk Institute for Biological Studies, La Jolla, California 92037, USA
    Nature 467:673-7. 2010

Collaborators

Detail Information

Publications28

  1. ncbi request reprint Information processing in the primate retina: circuitry and coding
    G D Field
    The Salk Institute, La Jolla, California 92037, USA
    Annu Rev Neurosci 30:1-30. 2007
    ..The functional importance of this structure is revealed by computational analysis of encoding and decoding, an approach that may be applicable to understanding the function of other neural circuits...
  2. ncbi request reprint Detection sensitivity and temporal resolution of visual signals near absolute threshold in the salamander retina
    E J Chichilnisky
    Systems Neurobiology Laboratory, The Salk Institute, La Jolla, California 92037, USA
    J Neurosci 25:318-30. 2005
    ....
  3. ncbi request reprint Temporal resolution of ensemble visual motion signals in primate retina
    E J Chichilnisky
    Systems Neurobiology, The Salk Institute and University of California, San Diego, La Jolla, California 92037, USA
    J Neurosci 23:6681-9. 2003
    ..These findings suggest that cortical neurons could filter their inputs on a time scale of tens of milliseconds, rather than relying on the precise times of individual input spikes, to sense motion most reliably...
  4. ncbi request reprint Functional asymmetries in ON and OFF ganglion cells of primate retina
    E J Chichilnisky
    Systems Neurobiology, The Salk Institute, La Jolla, California 92037, USA
    J Neurosci 22:2737-47. 2002
    ..These findings suggest specific mechanistic asymmetries in retinal ON and OFF circuits and differences in visual performance on the basis of the activity of ON and OFF parasol cells...
  5. ncbi request reprint A simple white noise analysis of neuronal light responses
    E J Chichilnisky
    Systems Neurobiology, The Salk Institute, La Jolla, CA 92037 1099, USA
    Network 12:199-213. 2001
    ..Advantages and disadvantages of the technique relative to classical approaches are discussed...
  6. ncbi request reprint Trichromatic opponent color classification
    E J Chichilnisky
    Department of Psychology, Stanford University, CA 94305, USA
    Vision Res 39:3444-58. 1999
    ..The effect of background light on classification was largely explained by separate gain changes in increment and decrement cone signals...
  7. ncbi request reprint Receptive-field microstructure of blue-yellow ganglion cells in primate retina
    E J Chichilnisky
    Department of Neurobiology, Stanford University, School of Medicine, Stanford, California 94305, USA
    Nat Neurosci 2:889-93. 1999
    ..Neighboring BY cells received common but unequal inputs from one or more S cones. Inputs from individual S cones differed in strength, indicating different synaptic weights, and summed approximately linearly to control BY cell firing...
  8. ncbi request reprint Adaptation to temporal contrast in primate and salamander retina
    D Chander
    Systems Neurobiology, The Salk Institute, La Jolla, California 92037-1099, USA
    J Neurosci 21:9904-16. 2001
    ..Functionally defined subclasses of ON and OFF cells also exhibited asymmetric adaptation. These findings indicate that contrast adaptation differs in parallel retinal circuits that convey distinct visual signals to the brain...
  9. ncbi request reprint Fidelity of the ensemble code for visual motion in primate retina
    E S Frechette
    The Salk Institute and University of California, San Diego, USA
    J Neurophysiol 94:119-35. 2005
    ..These findings reveal how faithfully the retinal population code conveys information about stimulus speed and the consequences for motion sensing in the brain...
  10. pmc Functional connectivity in the retina at the resolution of photoreceptors
    Greg D Field
    Systems Neurobiology Laboratories, Salk Institute for Biological Studies, La Jolla, California 92037, USA
    Nature 467:673-7. 2010
    ..These measurements reveal computations in a neural circuit at the elementary resolution of individual neurons...
  11. pmc Direction selectivity in the retina is established independent of visual experience and cholinergic retinal waves
    Justin Elstrott
    Neuroscience Graduate Program, University of California, San Diego, La Jolla, CA 92093, USA
    Neuron 58:499-506. 2008
    ..These data suggest that direction selectivity in the retina is established largely independent of patterned activity and is therefore likely to emerge as a result of complex molecular interactions...
  12. ncbi request reprint Precision of spike trains in primate retinal ganglion cells
    V J Uzzell
    Systems Neurobiology, The Salk Institute, 10010 North Torrey Pines Rd, La Jolla, CA 92037, USA
    J Neurophysiol 92:780-9. 2004
    ..These findings were consistent with a model in which firing probability was determined by a stimulus-driven free firing rate modulated by a recovery function representing the action potential absolute and relative refractory period...
  13. ncbi request reprint Electrical stimulation of mammalian retinal ganglion cells with multielectrode arrays
    Chris Sekirnjak
    The Salk Institute for Biological Studies, San Diego, California, USA
    J Neurophysiol 95:3311-27. 2006
    ..We review previous epiretinal stimulation studies and discuss our results in the context of 32 other publications, comparing threshold parameters and safety limits...
  14. pmc High-resolution electrical stimulation of primate retina for epiretinal implant design
    Chris Sekirnjak
    Systems Neurobiology Laboratory, The Salk Institute for Biological Studies, San Diego, California 92037, USA
    J Neurosci 28:4446-56. 2008
    ..The low-threshold, temporally precise, and spatially specific responses hold promise for the application of high-density arrays of small electrodes in epiretinal implants...
  15. pmc Receptive fields in primate retina are coordinated to sample visual space more uniformly
    Jeffrey L Gauthier
    Salk Institute for Biological Studies, La Jolla, California, United States of America
    PLoS Biol 7:e1000063. 2009
    ..These results show that the primate retina encodes light with an exquisitely coordinated array of RF shapes, illustrating a higher degree of functional precision in the neural circuitry than previously appreciated...
  16. pmc The structure of large-scale synchronized firing in primate retina
    Jonathon Shlens
    The Salk Institute, La Jolla, California 92037, USA
    J Neurosci 29:5022-31. 2009
    ..In sum, large-scale synchronized firing in the entire population of ON-parasol cells appears to reflect simple neighbor interactions, rather than a unique visual signal or a highly redundant coding scheme...
  17. ncbi request reprint Spatial properties and functional organization of small bistratified ganglion cells in primate retina
    Greg D Field
    Salk Institute for Biological Studies, La Jolla, California 92037, USA
    J Neurosci 27:13261-72. 2007
    ..Thus, despite their distinctive morphology and chromatic properties, SBCs exhibit two features of other retinal ganglion cell types: center-surround antagonism and regular mosaic sampling of visual space...
  18. ncbi request reprint Estimating information rates with confidence intervals in neural spike trains
    Jonathon Shlens
    Salk Institute, La Jolla, CA 92037, USA
    Neural Comput 19:1683-719. 2007
    ..Finally, we apply these ideas to a recording from a guinea pig retinal ganglion cell and compare results to a simple linear decoder...
  19. pmc Correlated firing among major ganglion cell types in primate retina
    Martin Greschner
    Systems Neurobiology Laboratory, Salk Institute for Biological Studies, La Jolla, CA, USA
    J Physiol 589:75-86. 2011
    ..Collectively, these results provide an overview of correlated firing across cell types in the primate retina, and constraints on the underlying mechanisms...
  20. ncbi request reprint The structure of multi-neuron firing patterns in primate retina
    Jonathon Shlens
    Department of Systems Neurobiology, The Salk Institute, La Jolla, California 92037, USA
    J Neurosci 26:8254-66. 2006
    ..This approach provides a way to define limits on the complexity of network interactions and thus may be relevant for probing the function of many neural circuits...
  21. ncbi request reprint Cone inputs to simple and complex cells in V1 of awake macaque
    Gregory D Horwitz
    Vision Center Laboratory, The Salk Institute for Biological Studies, La Jolla, California, USA
    J Neurophysiol 97:3070-81. 2007
    ..These results extend the findings on distinctions between simple and complex cell chromatic tuning observed in previous studies in anesthetized monkeys...
  22. ncbi request reprint Blue-yellow signals are enhanced by spatiotemporal luminance contrast in macaque V1
    Gregory D Horwitz
    Vision Center Laboratory, Howard Hughes Medical Institute, The Salk Institute for Biological Studies, 10010 N Torrey Pines Rd, La Jolla, CA 92037, USA
    J Neurophysiol 93:2263-78. 2005
    ..These findings indicate that important aspects of the cortical representation of color cannot be described by classical linear analysis, and reveal a possible neural correlate of perceptual color-luminance interactions...
  23. pmc High-sensitivity rod photoreceptor input to the blue-yellow color opponent pathway in macaque retina
    Greg D Field
    Salk Institute for Biological Studies, La Jolla, California, USA
    Nat Neurosci 12:1159-64. 2009
    ..Third, rod input to SBCs may be the substrate for behavioral biases toward perception of blue at mesopic light levels...
  24. pmc Loss of responses to visual but not electrical stimulation in ganglion cells of rats with severe photoreceptor degeneration
    Chris Sekirnjak
    The Salk Institute for Biological Studies, La Jolla, CA 92037, USA
    J Neurophysiol 102:3260-9. 2009
    ..These findings suggest that high-resolution epiretinal prosthetic devices may be effective in treating vision loss resulting from photoreceptor degeneration...
  25. pmc Uniform signal redundancy of parasol and midget ganglion cells in primate retina
    Jeffrey L Gauthier
    Salk Institute for Biological Studies, 10010 NorthTorrey Pines Road, La Jolla, CA 92037, USA
    J Neurosci 29:4675-80. 2009
    ....
  26. ncbi request reprint Seeing gray through the ON and OFF pathways
    E J Chichilnisky
    Department of Neurobiology, Stanford University, CA 94305, USA
    Vis Neurosci 13:591-6. 1996
    ..We interpret these asymmetries as differences in mechanisms of adaptation in the ON and OFF pathways, and suggest that they evolved to accommodate the range and physical sources of color signals in the two pathways...
  27. ncbi request reprint Estimating entropy rates with Bayesian confidence intervals
    Matthew B Kennel
    Institute for Nonlinear Science, University of California, San Diego, La Jolla, CA 92093 0402, USA
    Neural Comput 17:1531-76. 2005
    ..In related work, we apply these ideas to estimate the information rates between sensory stimuli and neural responses in experimental data (Shlens, Kennel, Abarbanel, & Chichilnisky, in preparation)...
  28. pmc Changes in physiological properties of rat ganglion cells during retinal degeneration
    Chris Sekirnjak
    Salk Institute for Biological Studies, 10010 N Torrey Pines Rd, La Jolla, CA 92037, USA
    J Neurophysiol 105:2560-71. 2011
    ..These results advance our understanding of the functional changes associated with retinal degeneration...

Research Grants17

  1. CRCNS: Complete functional characterization of a population of retinal ganglion c
    EDUARDO J CHICHILNISKY; Fiscal Year: 2010
    ..In summary, knowing how the entire retinal network encodes the visual scene in spike trains is a key element in understanding the healthy visual system and designing prosthetic treatments for retinas damaged by disease. ..
  2. Receptive field mosaics of midget, parasol, and small bistratified ganglion cells
    EDUARDO CHICHILNISKY; Fiscal Year: 2009
    ..In summary, knowing the functional organization of parasol, midget and small bistratified cells is a key element in understanding the healthy visual system and designing prosthetic treatments for retinas damaged by disease. ..
  3. Synchronized Firing in the Retina
    EDUARDO CHICHILNISKY; Fiscal Year: 2009
    ....
  4. Receptive field mosaics of midget, parasol, and small bistratified ganglion cells
    EDUARDO CHICHILNISKY; Fiscal Year: 2007
    ..In summary, knowing the functional organization of parasol, midget and small bistratified cells is a key element in understanding the healthy visual system and designing prosthetic treatments for retinas damaged by disease. ..
  5. Synchronized Firing in the Retina
    EDUARDO CHICHILNISKY; Fiscal Year: 2007
    ....
  6. ENSEMBLE CODING OF VISUAL INFORMATION IN THE RETINA
    EDUARDO CHICHILNISKY; Fiscal Year: 2004
    ..Aim 3. Does retinal signaling limit accuracy of behavioral and cortical motion sensing? This part will include psychophysical studies as well as correlation with recordings in MT obtained from other investigators. ..
  7. CRCNS: Complete functional characterization of a population of retinal ganglion c
    EDUARDO CHICHILNISKY; Fiscal Year: 2009
    ..In summary, knowing how the entire retinal network encodes the visual scene in spike trains is a key element in understanding the healthy visual system and designing prosthetic treatments for retinas damaged by disease. ..