Research Topics
| Hannah C CheungSummaryAffiliation: The University of Texas Country: USA Publications
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Detail Information
Publications
Global analysis of aberrant pre-mRNA splicing in glioblastoma using exon expression arraysHannah C Cheung
Department of Endocrine Neoplasia and Hormonal Disorders, University of Texas M, d, Anderson Cancer Center, Houston, TX 77030, USA
BMC Genomics 9:216. 2008..Validation studies were performed using RT-PCR on glioma cell lines, patient tumor and nontumor brain samples...
PTBP1-dependent regulation of USP5 alternative RNA splicing plays a role in glioblastoma tumorigenesisDaisy I Izaguirre
Department of Endocrine Neoplasia and Hormonal Disorders, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA
Mol Carcinog 51:895-906. 2012..These results support a role for aberrant RNA splicing in tumorigenesis and suggest that changes in relatively few genes may be sufficient to drive the process...
Splicing factors PTBP1 and PTBP2 promote proliferation and migration of glioma cell linesHannah C Cheung
Department of Endocrine Neoplasia and Hormonal Disorders, University of Texas, M D Anderson Cancer Center, Houston, TX 77030, USA
Brain 132:2277-88. 2009..Its actions on proliferation appear to be mediated, in part, through alternative splicing of RTN4...
Polypyrimidine tract binding protein and Notch1 are independently re-expressed in gliomaHannah C Cheung
Department of Endocrine Neoplasia and Hormonal Disorders, The University of Texas MD Anderson Cancer Center, Houston, 77030, USA
Mod Pathol 19:1034-41. 2006..This decrease in Notch1IC was not associated with increased PTB expression. We conclude that PTB, and Notch1 serve as independent and functionally unlinked markers of glioma progression...
Constitutional tandem duplication of 9q34 that truncates EHMT1 in a child with gangliogliomaHannah C Cheung
Texas Children s Cancer Center, Baylor College of Medicine, Houston, Texas, USA
Pediatr Blood Cancer 58:801-5. 2012..The ganglioglioma showed complex chromosomal aberrations with further duplication of the dup9q34. Thus, this unique tandem 9q34.3 duplication may impact brain tumor formation...
Identification of genetic susceptibility to childhood cancer through analysis of genes in parallelSharon E Plon
Texas Children s Cancer Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA
Cancer Genet 204:19-25. 2011..The failure to detect mutations in 87% of families highlights that a number of childhood cancer susceptibility genes remain to be discovered...
