Elissa J Chesler

Summary

Affiliation: The Jackson Laboratory
Country: USA

Publications

  1. doi request reprint Out of the bottleneck: the Diversity Outcross and Collaborative Cross mouse populations in behavioral genetics research
    Elissa J Chesler
    The Jackson Laboratory, 600 Main Street, Bar Harbor, ME, 04609, USA
    Mamm Genome 25:3-11. 2014
  2. pmc Genetic variation in hippocampal microRNA expression differences in C57BL/6 J X DBA/2 J (BXD) recombinant inbred mouse strains
    Michael J Parsons
    Mammalian Genetics Unit, Medical Research Council Harwell Oxfordshire, United Kingdom
    BMC Genomics 13:476. 2012
  3. doi request reprint Opportunities for bioinformatics in the classification of behavior and psychiatric disorders
    Elissa J Chesler
    The Jackson Laboratory, Bar Harbor, Maine, USA
    Int Rev Neurobiol 104:183-211. 2012
  4. pmc Quantitative trait loci for sensitivity to ethanol intoxication in a C57BL/6J×129S1/SvImJ inbred mouse cross
    Elissa J Chesler
    The Jackson Laboratory, 600 Main St, Bar Harbor, ME 04609, USA
    Mamm Genome 23:305-21. 2012
  5. pmc Comparison of threshold selection methods for microarray gene co-expression matrices
    Bhavesh R Borate
    Department of Animal Science, University of Tennessee, Knoxville, Tennessee, USA
    BMC Res Notes 2:240. 2009
  6. ncbi request reprint The importance of open-source integrative genomics to drug discovery
    Elissa J Chesler
    The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA
    Curr Opin Drug Discov Devel 13:310-6. 2010
  7. ncbi request reprint The Collaborative Cross, a community resource for the genetic analysis of complex traits
    Gary A Churchill
    The Jackson Laboratory, 600 Main Street Bar Harbor, Maine 04609, USA
    Nat Genet 36:1133-7. 2004
  8. pmc Accelerating discovery for complex neurological and behavioral disorders through systems genetics and integrative genomics in the laboratory mouse
    Jason A Bubier
    The Jackson Laboratory, Bar Harbor, Maine 04609, USA
    Neurotherapeutics 9:338-48. 2012
  9. doi request reprint Performing integrative functional genomics analysis in GeneWeaver.org
    Jeremy J Jay
    The Jackson Laboratory, Bar Harbor, ME, USA
    Methods Mol Biol 1101:13-29. 2014
  10. pmc A systematic comparison of genome-scale clustering algorithms
    Jeremy J Jay
    The Jackson Laboratory, Bar Harbor, ME 04609, USA
    BMC Bioinformatics 13:S7. 2012

Detail Information

Publications11

  1. doi request reprint Out of the bottleneck: the Diversity Outcross and Collaborative Cross mouse populations in behavioral genetics research
    Elissa J Chesler
    The Jackson Laboratory, 600 Main Street, Bar Harbor, ME, 04609, USA
    Mamm Genome 25:3-11. 2014
    ....
  2. pmc Genetic variation in hippocampal microRNA expression differences in C57BL/6 J X DBA/2 J (BXD) recombinant inbred mouse strains
    Michael J Parsons
    Mammalian Genetics Unit, Medical Research Council Harwell Oxfordshire, United Kingdom
    BMC Genomics 13:476. 2012
    ....
  3. doi request reprint Opportunities for bioinformatics in the classification of behavior and psychiatric disorders
    Elissa J Chesler
    The Jackson Laboratory, Bar Harbor, Maine, USA
    Int Rev Neurobiol 104:183-211. 2012
    ..With the perspective and application of bioinformatics, we can uncover the relationships among these systems and take steps forward in realizing the common and distinct bases of psychiatric disease...
  4. pmc Quantitative trait loci for sensitivity to ethanol intoxication in a C57BL/6J×129S1/SvImJ inbred mouse cross
    Elissa J Chesler
    The Jackson Laboratory, 600 Main St, Bar Harbor, ME 04609, USA
    Mamm Genome 23:305-21. 2012
    ..Uncovering candidate genes associated with variation in these phenotypes in this population could ultimately shed light on genetic factors underlying sensitivity to EtOH intoxication and risk for alcoholism in humans...
  5. pmc Comparison of threshold selection methods for microarray gene co-expression matrices
    Bhavesh R Borate
    Department of Animal Science, University of Tennessee, Knoxville, Tennessee, USA
    BMC Res Notes 2:240. 2009
    ..This study investigated threshold selection in the context of combinatorial network analysis of transcriptome data...
  6. ncbi request reprint The importance of open-source integrative genomics to drug discovery
    Elissa J Chesler
    The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA
    Curr Opin Drug Discov Devel 13:310-6. 2010
    ..Current analytic approaches use the full scale and scope of data, but require data sharing, interoperability and community recognition of the value of shared information...
  7. ncbi request reprint The Collaborative Cross, a community resource for the genetic analysis of complex traits
    Gary A Churchill
    The Jackson Laboratory, 600 Main Street Bar Harbor, Maine 04609, USA
    Nat Genet 36:1133-7. 2004
    ..The Collaborative Cross will provide a common reference panel specifically designed for the integrative analysis of complex systems and will change the way we approach human health and disease...
  8. pmc Accelerating discovery for complex neurological and behavioral disorders through systems genetics and integrative genomics in the laboratory mouse
    Jason A Bubier
    The Jackson Laboratory, Bar Harbor, Maine 04609, USA
    Neurotherapeutics 9:338-48. 2012
    ..Together, these model organism-based approaches can lead to a refinement of diagnostic categories and targeted treatment of neurological and psychiatric disease...
  9. doi request reprint Performing integrative functional genomics analysis in GeneWeaver.org
    Jeremy J Jay
    The Jackson Laboratory, Bar Harbor, ME, USA
    Methods Mol Biol 1101:13-29. 2014
    ..Users can retrieve curated gene set data, upload, store, and share their own experimental results and perform integrative analyses including novel algorithmic approaches for set-set integration of genes and functions. ..
  10. pmc A systematic comparison of genome-scale clustering algorithms
    Jeremy J Jay
    The Jackson Laboratory, Bar Harbor, ME 04609, USA
    BMC Bioinformatics 13:S7. 2012
    ..In the present study, a variety of parametric and graph theoretical clustering algorithms are compared using well-characterized transcriptomic data at a genome scale from Saccharomyces cerevisiae...
  11. pmc GeneWeaver: a web-based system for integrative functional genomics
    Erich J Baker
    School of Engineering and Computer Science, Baylor University, Waco, TX 76798, USA
    Nucleic Acids Res 40:D1067-76. 2012
    ..An empirical 'ontology' is discovered from the aggregate of experimental knowledge around user-defined areas of biological inquiry...