Heather L Chandler

Summary

Affiliation: The Ohio State University
Country: USA

Publications

  1. doi request reprint Induction of posterior capsule opacification by hyaluronic acid in an ex vivo model
    Heather L Chandler
    College of Optometry, The Ohio State University, Columbus, Ohio, USA
    Invest Ophthalmol Vis Sci 53:1835-45. 2012
  2. doi request reprint Immunohistochemical analysis of ocular hemangiomas and hemangiosarcomas in dogs
    Heather L Chandler
    The Ohio State University, College of Optometry, 320 West 10th Avenue, Columbus, OH 43210, USA
    Vet Ophthalmol 12:83-90. 2009
  3. doi request reprint Prevention of UV-induced damage to the anterior segment using class I UV-absorbing hydrogel contact lenses
    Heather L Chandler
    Ohio State University, College of Optometry, Columbus, Ohio, USA
    Invest Ophthalmol Vis Sci 51:172-8. 2010
  4. doi request reprint Modulation of matrix metalloproteinases by ultraviolet radiation in the canine cornea
    Heather L Chandler
    Department of Veterinary Biosciences, College of Veterinary Medicine, The Ohio State University, 1900 Coffey Road, Columbus, OH 43201, USA
    Vet Ophthalmol 11:135-44. 2008
  5. doi request reprint In vivo effects of adjunctive tetracycline treatment on refractory corneal ulcers in dogs
    Heather L Chandler
    College of Optometry, The Ohio State University, Columbus, OH 43210, USA
    J Am Vet Med Assoc 237:378-86. 2010
  6. pmc The effect of phosphorylated Akt inhibition on posterior capsule opacification in an ex vivo canine model
    Heather L Chandler
    College of Optometry, The Ohio State University, Columbus, OH 43210, USA
    Mol Vis 16:2202-14. 2010
  7. doi request reprint Ultraviolet absorption by contact lenses and the significance on the ocular anterior segment
    Heather Chandler
    College of Optometry, Ohio State University, Columbus, OH 43210, USA
    Eye Contact Lens 37:259-66. 2011
  8. pmc Prevention of posterior capsular opacification through cyclooxygenase-2 inhibition
    Heather L Chandler
    Ohio State University, Veterinary Biosciences, Columbus, OH 43210, USA
    Mol Vis 13:677-91. 2007
  9. ncbi request reprint The role of the slug transcription factor in cell migration during corneal re-epithelialization in the dog
    Heather L Chandler
    Veterinary Biosciences, The Ohio State University, 1900 Coffey Road, Columbus, OH 43210, USA
    Exp Eye Res 84:400-11. 2007
  10. ncbi request reprint Ultraviolet irradiation up-regulates telomerase transcription and activity in lens epithelial cells
    Carmen M H Colitz
    Departments of Veterinary Clinical Science, The Ohio State University, Columbus, OH, USA
    Vet Ophthalmol 9:379-85. 2006

Collaborators

Detail Information

Publications21

  1. doi request reprint Induction of posterior capsule opacification by hyaluronic acid in an ex vivo model
    Heather L Chandler
    College of Optometry, The Ohio State University, Columbus, Ohio, USA
    Invest Ophthalmol Vis Sci 53:1835-45. 2012
    ....
  2. doi request reprint Immunohistochemical analysis of ocular hemangiomas and hemangiosarcomas in dogs
    Heather L Chandler
    The Ohio State University, College of Optometry, 320 West 10th Avenue, Columbus, OH 43210, USA
    Vet Ophthalmol 12:83-90. 2009
    ..To determine if molecular markers typically associated with ultraviolet exposure could be detected in canine ocular hemangiomas (HA) and hemangiosarcomas (HSA)...
  3. doi request reprint Prevention of UV-induced damage to the anterior segment using class I UV-absorbing hydrogel contact lenses
    Heather L Chandler
    Ohio State University, College of Optometry, Columbus, Ohio, USA
    Invest Ophthalmol Vis Sci 51:172-8. 2010
    ..To determine whether class I ultraviolet (UV) light-blocking contact lenses prevent UV-induced pathologic changes in a rabbit model...
  4. doi request reprint Modulation of matrix metalloproteinases by ultraviolet radiation in the canine cornea
    Heather L Chandler
    Department of Veterinary Biosciences, College of Veterinary Medicine, The Ohio State University, 1900 Coffey Road, Columbus, OH 43201, USA
    Vet Ophthalmol 11:135-44. 2008
    ..To determine whether ultraviolet (UV) radiation can modulate expression and regulation of matrix metalloproteinases (MMP) in the canine cornea and to examine the expression of MMPs in canine chronic superficial keratitis (CSK)...
  5. doi request reprint In vivo effects of adjunctive tetracycline treatment on refractory corneal ulcers in dogs
    Heather L Chandler
    College of Optometry, The Ohio State University, Columbus, OH 43210, USA
    J Am Vet Med Assoc 237:378-86. 2010
    ..To evaluate effect of adjunctive treatment with tetracycline analogues on time to complete corneal reepithelialization in dogs with nonhealing (ie, refractory) corneal ulcers...
  6. pmc The effect of phosphorylated Akt inhibition on posterior capsule opacification in an ex vivo canine model
    Heather L Chandler
    College of Optometry, The Ohio State University, Columbus, OH 43210, USA
    Mol Vis 16:2202-14. 2010
    ..To evaluate whether inhibition of phosphorylated Akt (pAkt) would reduce or prevent posterior capsule opacification (PCO) in an ex vivo canine lens capsule model...
  7. doi request reprint Ultraviolet absorption by contact lenses and the significance on the ocular anterior segment
    Heather Chandler
    College of Optometry, Ohio State University, Columbus, OH 43210, USA
    Eye Contact Lens 37:259-66. 2011
    ..This article will discuss the impact of UV exposure on ocular tissue and the need for adequate UV protection, with particular emphasis on UV-blocking contact lenses...
  8. pmc Prevention of posterior capsular opacification through cyclooxygenase-2 inhibition
    Heather L Chandler
    Ohio State University, Veterinary Biosciences, Columbus, OH 43210, USA
    Mol Vis 13:677-91. 2007
    ..We also wanted to learn if inhibition of the enzymatic activity of COX-2 could prevent PCO formation...
  9. ncbi request reprint The role of the slug transcription factor in cell migration during corneal re-epithelialization in the dog
    Heather L Chandler
    Veterinary Biosciences, The Ohio State University, 1900 Coffey Road, Columbus, OH 43210, USA
    Exp Eye Res 84:400-11. 2007
    ....
  10. ncbi request reprint Ultraviolet irradiation up-regulates telomerase transcription and activity in lens epithelial cells
    Carmen M H Colitz
    Departments of Veterinary Clinical Science, The Ohio State University, Columbus, OH, USA
    Vet Ophthalmol 9:379-85. 2006
    ..To evaluate whether the cornea would protect lenses from such changes, whole globes, as well as isolated lenses, were exposed to UVR, and lenses were evaluated for changes in telomerase activity...
  11. doi request reprint All-trans retinoic Acid regulates cx43 expression, gap junction communication and differentiation in primary lens epithelial cells
    Amy C Long
    The Ohio State University, Interdisciplinary Ph D Program in Nutrition, Department of Human Nutrition, Department of Ophthalmology, Biomedical Engineering Center, College of Optometry, Department of Veterinary Clinical Sciences, Columbus, Ohio, USA
    Curr Eye Res 35:670-9. 2010
    ..To examine the effect of all-trans retinoic acid (ATRA) treatment on connexin 43 (Cx43) expression, gap junction intercellular communication (GJIC), and cellular differentiation in primary canine lens epithelial cells (LEC)...
  12. ncbi request reprint Ultraviolet radiation-induced corneal degeneration in 129 mice
    Kimberly M Newkirk
    Department of Veterinary Biosciences, College of Veterinary Medicine, The Ohio State University, Columbus, Ohio 43210, USA
    Toxicol Pathol 35:819-26. 2007
    ..Based on this finding, we propose that the loss of keratocytes observed in the chronic study was due to UVR-induced apoptosis...
  13. doi request reprint The acute cutaneous inflammatory response is attenuated in Slug-knockout mice
    Kimberly M Newkirk
    Department of Veterinary Biosciences, College of Veterinary Medicine, The Ohio State University, Columbus, OH, USA
    Lab Invest 88:831-41. 2008
    ..Our findings indicate an unexpected but important role for Slug in the acute cutaneous inflammatory response to UVR...
  14. doi request reprint Effect of grape polyphenols on oxidative stress in canine lens epithelial cells
    Curtis A Barden
    Department of Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, Columbus, OH 43210, USA
    Am J Vet Res 69:94-100. 2008
    ..To evaluate whether the effects of oxidative stress could be attenuated in cultures of canine lens epithelial cells (LECs) by incubation with grape seed proanthocyanidin extract (GSE), resveratrol (RES), or a combination of both (GSE+RES)...
  15. pmc Snai2 expression enhances ultraviolet radiation-induced skin carcinogenesis
    Kimberly M Newkirk
    Department of Veterinary Biosciences, College of Veterinary Medicine, The Ohio State University, Columbus, OH 43235, USA
    Am J Pathol 171:1629-39. 2007
    ..This study confirms a role for Snai2 in EMT, but demonstrates that Snai2 expression is not required for the development or progression of UVR-induced skin tumors...
  16. pmc Tear proteomics in keratoconus
    Catherine Pannebaker
    College of Optometry, The Ohio State University, Columbus, OH 43210, USA
    Mol Vis 16:1949-57. 2010
    ..The purpose of this work was to identify potential tear-film based proteins expressed in keratoconus...
  17. doi request reprint Evaluation of extractants and precipitants in tear film proteomic analyses
    Daniel R Powell
    Vision Science, The Ohio State University College of Optometry, Columbus, Ohio 43210, USA
    Optom Vis Sci 87:854-60. 2010
    ..To determine the efficiency of several protein extraction or precipitation treatments used in proteomic analyses...
  18. doi request reprint Analysis of the transport of and cytotoxic effects for nalbuphine solution in corneal cells
    Ronald A Spatola
    Department of Clinical Sciences, College of Veterinary Medicine, The Ohio State University, Columbus, OH 43210, USA
    Am J Vet Res 73:1987-95. 2012
    ..To assess the in vitro effects of various nalbuphine concentrations on viability and wound healing ability of corneal cells and potential drug transport through the corneal epithelium...
  19. doi request reprint Role of bacteria in the pathogenesis of recurrent uveitis in horses from the southeastern United States
    Brian C Gilger
    Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27606, USA
    Am J Vet Res 69:1329-35. 2008
    ....
  20. ncbi request reprint Molecular biology for the clinician: understanding current methods
    Heather L Chandler
    Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Ohio State University, Columbus, Ohio 43210, USA
    J Am Anim Hosp Assoc 42:326-35. 2006
    ..To understand these assays requires some basic understanding of the principles of molecular biology. This paper provides basic information on the methodology and techniques used in these assays...
  21. doi request reprint Distribution and amount of pigment within the ciliary body and iris of dogs with blue and brown irides
    Kim M Newkirk
    Department of Pathobiology, College of Veterinary Medicine, University of Tennessee, Knoxville, TN 37996, USA
    Vet Ophthalmol 13:76-80. 2010
    ..Compare the amount and distribution of pigment in normal canine eyes with blue and brown irides...