Research Topics
| Mark S ChambersSummaryAffiliation: The University of Texas Country: USA Publications
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Detail Information
Publications
Anterior key method for indexing orbital prosthesesMark S Chambers
Department of Head and Neck Surgery, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030 4095, USA
J Prosthet Dent 87:102-5. 2002..Because indexing is performed from the anterior aspect of the cast, damage is minimized, fewer modifications are required, and the mold can be preserved for repeated use...- Obturation of the partial soft palate defectMark S Chambers
Department of Head and Neck Surgery, M D Anderson Cancer Center, The University of Texas, Houston 77030 4009 USA
J Prosthet Dent 91:75-9. 2004..This article presents a technique for recording the contours of a partial soft-palate defect for prosthetic obturation... - Cevimeline for the treatment of postirradiation xerostomia in patients with head and neck cancerMark S Chambers
Department of Head and Neck Surgery, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
Int J Radiat Oncol Biol Phys 68:1102-9. 2007..To study the efficacy and safety of cevimeline in two double-blind trials (Studies 003 and 004) enrolling patients with head and neck cancer in whom xerostomia developed after radiotherapy... - Open-label, long-term safety study of cevimeline in the treatment of postirradiation xerostomiaMark S Chambers
Department of Head and Neck Surgery, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
Int J Radiat Oncol Biol Phys 69:1369-76. 2007..To assess the safety of long-term cevimeline treatment of radiation-induced xerostomia in patients with head-and-neck cancer; and to assess the efficacy of cevimeline in these patients... - Erratum to "Clinical evaluation of the intraoral fluoride releasing system in radiation-induced xerostomic subjects. Part 2: Phase I study"Mark S Chambers
Department of Head and Neck Surgery, Department of Radiation Oncology, M D Anderson Cancer Center, Houston, TX 77030, USA
Oral Oncol 43:98-105. 2007..It would be more convenient than the daily home application of a tray of 0.4% stannous fluoride or 1.1% sodium fluoride gel, and avoids the problem of variable patient compliance... - Clinical evaluation of the intraoral fluoride releasing system in radiation-induced xerostomic subjects. Part 1: FluoridesMark S Chambers
Department of Head and Neck Surgery, Department of Radiation Oncology, M D Anderson Cancer Center, Houston, TX 77030, USA
Oral Oncol 42:934-45. 2006..Part 1 discusses the historical and currently available fluoride preparations and Part 2 presents data of a recently completed trial investigating the benefit of an intraoral sodium fluoride releasing system... - Mutans streptococci in xerostomic cancer patients after pilocarpine therapy: a pilot studyMark S Chambers
The University of Texas, M D Anderson Cancer Center, MDACC, Department of Head and Neck Surgery, Houston, Texas 77030 4009, USA
Oral Surg Oral Med Oral Pathol Oral Radiol Endod 99:180-4. 2005..Opiod- and/or radiation-induced xerostomia in cancer patients is frequently associated with elevated levels of cariogenic mutans streptococci (MS)... - Intensity-modulated radiotherapy: is xerostomia still prevalent?Mark S Chambers
Department of Head and Neck Surgery, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030 4009, USA
Curr Oncol Rep 7:131-6. 2005.... 
Salivary flow rates measured during radiation therapy in head and neck cancer patients: a pilot study assessing salivary sediment formationMark S Chambers
Department of Head and Neck Surgery, Department of Radiation Oncology, M D Anderson Cancer Center, Houston, TX 77030 4009, USA
J Prosthet Dent 100:142-6. 2008..Determining the impact that salivary sediments have on measured salivary flow rates during radiation is important for management of patients...- Clinical evaluation of the intraoral fluoride releasing system in radiation-induced xerostomic subjects. Part 2: Phase I studyMark S Chambers
Department of Head and Neck Surgery, Department of Radiation Oncology, M D Anderson Cancer Center, Houston, TX 77030, USA
Oral Oncol 42:946-53. 2006..It would be more convenient than the daily home application of a tray of 0.4% stannous fluoride or 1.1% sodium fluoride gel, and avoids the problem of variable patient compliance... - Radiation-induced xerostomiaMark S Chambers
Department of Head and Neck Surgery, The University of Texas, M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030 4009, USA
Head Neck 29:58-63. 2007..Radiation-induced xerostomia is a frequent and usually permanent side effect of radiation therapy for head and neck cancer. We summarize recent developments in the prevention and treatment of radiation-induced xerostomia... - Radiation-induced xerostomia in patients with head and neck cancer: pathogenesis, impact on quality of life, and managementMark S Chambers
Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, USA
Head Neck 26:796-807. 2004..Xerostomia is a common, debilitating complication of radiation therapy (RT) for head and neck cancer. This article reviews the pathogenesis of radiation-induced xerostomia, its impact on quality of life (QOL), and treatment options... - Beam path toxicities to non-target structures during intensity-modulated radiation therapy for head and neck cancerDavid I Rosenthal
Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX, USA
Int J Radiat Oncol Biol Phys 72:747-55. 2008..This study estimates the doses and toxicities to nontarget structures during IMRT... - Intensity-modulated radiation therapy and xerostomiaMark S Chambers
Department of Head and Neck Surgery, University of Texas M.D. Anderson Cancer Center, Houston, Texas 77030, USA
J Calif Dent Assoc 34:743-8. 2006.... - Measuring head and neck cancer symptom burden: the development and validation of the M. D. Anderson symptom inventory, head and neck moduleDavid I Rosenthal
Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas, USA
Head Neck 29:923-31. 2007.... - The M. D. Anderson symptom inventory-head and neck module, a patient-reported outcome instrument, accurately predicts the severity of radiation-induced mucositisDavid I Rosenthal
Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX, USA
Int J Radiat Oncol Biol Phys 72:1355-61. 2008.... - Further experience with modification of an intraluminal button for hands-free tracheoesophageal speech after laryngectomyJan S Lewin
Department of Head and Neck Surgery, The University of Texas, M D Anderson Cancer Center, Houston, TX 77230 1402, USA
J Prosthet Dent 102:328-31. 2009..A technique is presented for modification of a standard silicone laryngectomy button to facilitate hands-free TE speech after total laryngectomy... - Psychosocial and economic impact of cancerLinda S Elting
Section of Health Services Research, Department of Biostatistics, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 447, Houston, TX 77030, USA
Dent Clin North Am 52:231-52, x. 2008.... - Acupuncture for radiation-induced xerostomia in patients with cancer: a pilot studyM Kay Garcia
Integrative Medicine, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
Head Neck 31:1360-8. 2009..This pilot study evaluated if acupuncture can alleviate radiation-induced xerostomia among patients with cancer. Secondary objectives were to assess the effects of acupuncture on salivary flow and quality of life (QOL)... - Multiple regions-of-interest analysis of setup uncertainties for head-and-neck cancer radiotherapyLifei Zhang
Department of Radiation Physics, The University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA
Int J Radiat Oncol Biol Phys 64:1559-69. 2006..CONCLUSIONS: We found variability in setup corrections for different regions of head-and-neck anatomy. These relative positional variations should be considered when making setup corrections or designing treatment margins... - Facial prosthetic rehabilitation: preprosthetic surgical techniques and biomaterialsJames C Lemon
Section of Oncologic Dentistry, Department of Head and Neck Surgery, MD Anderson Cancer Center, University of Texas, 1515 Holcombe Boulevard, Houston, TX 77030, USA
Curr Opin Otolaryngol Head Neck Surg 13:255-62. 2005..SUMMARY: This review presents current concepts regarding facial prosthetic rehabilitation of patients with head and neck cancer and facial prosthetic biomaterials... - Custom modification of the Blom-Singer tracheostoma valve housingJames C Lemon
Department of Head and Neck Surgery, University of Texas M.D. Anderson Cancer Center, Houston 77030, USA
J Prosthodont 12:17-20. 2003..A punch biopsy instrument is used to cut uniform holes around the housing device to allow for permeation of the silicone mixture for better mechanical adherence of the materials... - A phase II study to assess the efficacy of amifostine for submandibular/sublingual salivary sparing during the treatment of head and neck cancer with intensity modulated radiation therapy for parotid salivary sparingDavid I Rosenthal
The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
Semin Oncol 31:25-8. 2004.... - How to reduce radiation-related toxicity in patients with cancer of the head and neckAdam S Garden
Department of Radiation Oncology and Head and Neck Surgery, The University of Texas M D Anderson Cancer Center, Houston TX, 77030, USA
Curr Oncol Rep 8:140-5. 2006..Minimizing radiation dose to these tissues may lower the incidence of radiation-induced dysphagia... - A technique for the fabrication of an immediate mandibular surgical stent securing a skin graftKelley L Tomsett
Department of Head and Neck Surgery, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030-4009, USA
J Prosthet Dent 93:395-7. 2005..This article describes an efficient and accurate method of fabricating an immediate mandibular surgical stent in the operating room setting... - Head and neck radiation and mucositisAdam S Garden
Departments of Radiation Oncology and Head and Neck Surgery, University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA
Curr Opin Support Palliat Care 1:30-4. 2007..We will review the recent literature that has provided new insights into the pathogenesis, metrics and therapeutics of mucositis... - Oral rehabilitation of a mandibular discontinuity defect: a clinical reportPeter J Gerngross
Michael E DeBakey V A Medical Center, Houston, USA
Tex Dent J 125:438-41. 2008..It is important to inform them that prosthetic reconstruction may restore structures and continuity, but it may not restore function... - A phase II study of gefitinib for aggressive cutaneous squamous cell carcinoma of the head and neckCarol M Lewis
Department of Head and Neck Surgery, University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA
Clin Cancer Res 18:1435-46. 2012..To determine the disease control rate and toxicity of treating patients with aggressive cutaneous squamous cell carcinoma (CSCC) with neoadjuvant gefitinib... - Three synchronous HPV-associated squamous cell carcinomas of Waldeyer's ring: case report and comparison with Slaughter's model of field cancerizationSusan L McGovern
Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
Head Neck 32:1118-24. 2010..The rate of synchronous lesions in human papillomavirus (HPV)-positive oropharyngeal cancers is unknown... - Period between completion of radiation therapy and prosthetic rehabilitation in edentulous patients: a retrospective studyPeter J Gerngross
Veteran's Administration Hospital, Houston, Texas, USA
J Prosthodont 14:110-21. 2005..There appears to be no difference in the number of pre- and post-insertion complications as a function of the time delay from oral surgical procedure to start of radiation treatment (10 to 21 days vs. 22 days or more)... - Stent fabrication for graft immobilization following wide surgical excision of myofibroblastic sarcoma of the buccal mucosa: a clinical reportIoli Ioanna Artopoulou
Department of Head and Neck Surgery, Section of Oncologic Dentistry and Prosthodontics, University of Texas M D Anderson Cancer Center, Houston, 77230 1402, USA
J Prosthet Dent 95:280-5. 2006..A situation of a surgically excised myofibrosarcoma of the buccal mucosa is reported. In this patient, a stent was fabricated to stabilize a split-thickness skin graft used for the buccal mucosa reconstruction... - Association between microbial flora and tissue abnormality around dental implants penetrating the skin in reconstructed oral cancer patientsAyman Ahmed
Section of Oncologic Dentistry and Prosthodontics, Department of Head and Neck Surgery, M D Anderson Cancer Center, University of Texas, Houston, TX, USA
Int J Oral Maxillofac Implants 27:684-94. 2012..This pilot clinical trial identified the oral microflora of the peri-implant sulcus of cancer patients with jaw reconstruction and compared sites with and without clinical signs of inflammation... - Locking retentive attachment for an implant-retained auricular prosthesisJames C Lemon
Department of Head and Neck Surgery, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA
J Prosthet Dent 87:336-8. 2002..This article describes the use of the Slant-Lock retention system with an implant-retained auricular prosthesis... - In vitro effect of microwave irradiation on the retentive force of magnetsJames C Lemon
M.D. Anderson Canncer Center and University of Texas Health Science Center at Houston, Dental Branch, Houston, TX 77030, USA
J Prosthet Dent 91:368-73. 2004..3 N, a reduction of 12%). CONCLUSION: If a prosthesis is processed using a microwave and contains samarium cobalt magnets, the retentive force may be reduced up to 12% under specific conditions... - Postsurgical use of prosthetic palatal appliances. Two case reportsIoli-Ioanna Artopoulou
Department of Head and Neck Surgery, The University of Texas M. D. Anderson Cancer Center, Houston 77230-1402, USA
J Clin Pediatr Dent 30:105-8. 2005..Surgical and orthodontic interventions are essential and prosthetic palatal appliances play an important role not only throughout the patient's treatment course, but also in the treatment of unfavorable surgical sequelae... - Customization of the voice prosthesis to prevent leakage from the enlarged tracheoesophageal puncture: results of a prospective trialJan S Lewin
Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA
Laryngoscope 122:1767-72. 2012.... - Adaptive radiotherapy for head-and-neck cancer: initial clinical outcomes from a prospective trialDavid L Schwartz
Department of Radiation Medicine, Hofstra North Shore Long Island Jewish School of Medicine, New Hyde Park, NY 11040, USA
Int J Radiat Oncol Biol Phys 83:986-93. 2012..To present pilot toxicity and survival outcomes for a prospective trial investigating adaptive radiotherapy (ART) for oropharyngeal squamous cell carcinoma... - Risk, outcomes, and costs of radiation-induced oral mucositis among patients with head-and-neck malignanciesLinda S Elting
Section of Health Services Research, Department of Biostatistics, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
Int J Radiat Oncol Biol Phys 68:1110-20. 2007..To study the risk, outcomes, and costs of radiation-induced oral mucositis (OM) among patients receiving radiotherapy (RT) to head and neck primary cancers... - Diagnosis of premalignant lesions and early cancers of the oral cavityAnn M Gillenwater
Department of Head and Neck Surgery, Anderson Cancer Center, The University of Texas, Houston, USA
Tex Dent J 123:512-20. 2006 - Sjögren's syndromeMark S Chambers
Department of Head and Neck Surgery, The University of Texas, M D Anderson Cancer Center, Houston 77030 4009, USA
ORL Head Neck Nurs 22:22-30; quiz 32-3. 2004..This article describes saliva and salivary function, the pathogenesis of SS, the current treatment of xerostomia, and quality of life issues related to salivary dysfunction... - Facial moulage: the effect of a retarder on compressive strength and working and setting times of irreversible hydrocolloid impression materialJames C Lemon
M.D. Anderson Cancer Center and Dental Branch, University of Texas Health Science Center at Houston, 1515 Holcombe Boulevard, Houston, TX 77030-4095, USA
J Prosthet Dent 90:276-81. 2003.... - How I do it: a technique for oral wound irrigation following maxillectomy and mandibulectomyMark S Chambers
Department of Head and Neck Surgery, University of Texas M.D. Anderson Cancer Center (MDACC, Houston, Texas, USA
ORL Head Neck Nurs 21:27-8. 2003.... - Treatment strategy for patients with ectodermal dysplasia: a case reportJack W Martin
Department of Head and Neck Surgery, MDACC, Houston, TX 77030-4009, USA
J Clin Pediatr Dent 29:113-8. 2005..With any form of ED, children may display a range of symptoms and challenging rehabilitation. This clinical report presents the treatment plan for a young patient with ED and anodontia requiring prosthetic restoration... - Modification of the Barton button for tracheoesophageal speech: an innovative maxillofacial prosthetic techniqueJames C Lemon
Department of Head and Neck Surgery, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030-4095, USA
J Prosthet Dent 87:236-9. 2002..This article presents a technique for modification of the Barton button to increase its successful use by tracheoesophageal speakers... - A mold-making procedure for multiple orbital prostheses fabricationTrakol Mekayarajjananonth
Faculty of Dentistry, Chulalongkorn University, Bangkok, Thailand
J Prosthet Dent 90:97-100. 2003..The following method provides a mold resistant to these problems with light-polymerized resin surrounding the palpebral part of the orbital mold... - Risk of osteoradionecrosis after extraction of impacted third molars in irradiated head and neck cancer patientsHee Kyun Oh
Department of Oral and Maxillofacial Surgery, College of Dentistry, Chonnam National University, South Korea
J Oral Maxillofac Surg 62:139-44. 2004..This study was performed to compare the risk of osteoradionecrosis (ORN) in head and neck cancer patients in whom 1 or more impacted third molars were extracted before radiotherapy with patients whose impacted third molars were left intact... - Clinical commentary on prophylactic treatment of radiation-induced xerostomiaMark S Chambers
Arch Otolaryngol Head Neck Surg 129:251-2. 2003 - 6,7-Dihydro-2-benzothiophen-4(5H)-ones: a novel class of GABA-A alpha5 receptor inverse agonistsMark S Chambers
Merck Sharp and Dohme Research Laboratories, The Neuroscience Research Centre, Terlings Park, Eastwick Road, Harlow, Essex CM20 2QR, UK
J Med Chem 45:1176-9. 2002..In particular, 6,6-dimethyl-3-(2-hydroxyethyl)thio-1-(thiazol-2-yl)-6,7-dihydro-2-benzothiophen-4(5H)-one (26) has been identified as a functionally selective GABA-A alpha5 inverse agonist... - Interactions of pigments and opacifiers on color stability of MDX4-4210/type A maxillofacial elastomers subjected to artificial agingSudarat Kiat-Amnuay
Department of Restorative Dentistry and Biomaterials, University of Texas Dental Branch at Houston, 77030, USA
J Prosthet Dent 95:249-57. 2006..The color instability and degradation of maxillofacial elastomers limit the function and cosmetic quality of facial prostheses... - Identification of a novel, selective GABA(A) alpha5 receptor inverse agonist which enhances cognitionMark S Chambers
Merck Sharp and Dohme Research Laboratories, The Neuroscience Research Centre, Terlings Park, Eastwick Road, Harlow, Essex, CM20 2QR, UK
J Med Chem 46:2227-40. 2003.... - A maxillary fibro-osseous lesion: differential diagnosis and case reportMark S Chambers
Department of Otolaryngology, University of West Virginia, USA
Tex Dent J 119:12-9. 2002