JON MICHAEL BURNHAM

Summary

Affiliation: The Children's Hospital of Philadelphia
Country: USA

Publications

  1. ncbi Inflammatory diseases and bone health in children
    Jon M Burnham
    Department of Pediatrics and Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Curr Opin Rheumatol 24:548-53. 2012
  2. ncbi Vitamin D supplementation in the pediatric rheumatology clinic
    Emily Von Scheven
    Pediatric Rheumatology, University of California, San Francisco, Box 0107, 533 Parnassus Avenue, Room U 126, San Francisco, CA 94143, USA
    Curr Rheumatol Rep 13:110-6. 2011
  3. ncbi Whole body BMC in pediatric Crohn disease: independent effects of altered growth, maturation, and body composition
    Jon M Burnham
    Children s Hospital of Philadelphia, Department of Pediatrics, University of Pennsylvania, 34th Street and Civic Center Boulevard, Philadelphia, PA 19104, USA
    J Bone Miner Res 19:1961-8. 2004
  4. ncbi Body-composition alterations consistent with cachexia in children and young adults with Crohn disease
    Jon M Burnham
    Department of Pediatrics, Division of Rheumatology, The Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Am J Clin Nutr 82:413-20. 2005
  5. ncbi Childhood onset arthritis is associated with an increased risk of fracture: a population based study using the General Practice Research Database
    J M Burnham
    Children s Hospital of Philadelphia, Room 1579 CHOP North, 3535 Market Street, Philadelphia, PA 19104, USA
    Ann Rheum Dis 65:1074-9. 2006
  6. ncbi The dysfunctional muscle-bone unit in juvenile idiopathic arthritis
    J M Burnham
    The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA
    J Musculoskelet Neuronal Interact 6:351-2. 2006
  7. ncbi Alterations in proximal femur geometry in children treated with glucocorticoids for Crohn disease or nephrotic syndrome: impact of the underlying disease
    Jon M Burnham
    The Children s Hospital of Philadelphia, Philadelphia PA 19104, USA
    J Bone Miner Res 22:551-9. 2007
  8. ncbi Bone density, structure, and strength in juvenile idiopathic arthritis: importance of disease severity and muscle deficits
    Jon M Burnham
    Children s Hospital of Philadelphia, and University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Arthritis Rheum 58:2518-27. 2008
  9. ncbi Divergent effects of glucocorticoids on cortical and trabecular compartment BMD in childhood nephrotic syndrome
    Rachel J Wetzsteon
    Department of Pediatrics, Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
    J Bone Miner Res 24:503-13. 2009
  10. ncbi Determinants of changes in linear growth and body composition in incident pediatric Crohn's disease
    Meena Thayu
    Department of Pediatrics, The Children s Hospital of Philadelphia, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    Gastroenterology 139:430-8. 2010

Research Grants

  1. The Functional Muscle-Bone Unit in JRA
    Jon Burnham; Fiscal Year: 2007

Detail Information

Publications22

  1. ncbi Inflammatory diseases and bone health in children
    Jon M Burnham
    Department of Pediatrics and Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Curr Opin Rheumatol 24:548-53. 2012
    ..Proinflammatory cytokines and glucocorticoid therapy are likely key factors that impair bone accrual, along with downstream effects including malnutrition, pubertal delay, low muscle mass and physical inactivity...
  2. ncbi Vitamin D supplementation in the pediatric rheumatology clinic
    Emily Von Scheven
    Pediatric Rheumatology, University of California, San Francisco, Box 0107, 533 Parnassus Avenue, Room U 126, San Francisco, CA 94143, USA
    Curr Rheumatol Rep 13:110-6. 2011
    ....
  3. ncbi Whole body BMC in pediatric Crohn disease: independent effects of altered growth, maturation, and body composition
    Jon M Burnham
    Children s Hospital of Philadelphia, Department of Pediatrics, University of Pennsylvania, 34th Street and Civic Center Boulevard, Philadelphia, PA 19104, USA
    J Bone Miner Res 19:1961-8. 2004
    ..Adjustment for lean mass eliminated the bone deficit in CD. Steroid exposure was associated with short stature but not bone deficits relative to height...
  4. ncbi Body-composition alterations consistent with cachexia in children and young adults with Crohn disease
    Jon M Burnham
    Department of Pediatrics, Division of Rheumatology, The Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Am J Clin Nutr 82:413-20. 2005
    ..Crohn disease (CD) in children is associated with low body mass index (BMI), poor growth, and delayed maturation; alterations in lean and fat mass, however, are poorly characterized...
  5. ncbi Childhood onset arthritis is associated with an increased risk of fracture: a population based study using the General Practice Research Database
    J M Burnham
    Children s Hospital of Philadelphia, Room 1579 CHOP North, 3535 Market Street, Philadelphia, PA 19104, USA
    Ann Rheum Dis 65:1074-9. 2006
    ..Childhood onset arthritis is associated with low bone mass and strength...
  6. ncbi The dysfunctional muscle-bone unit in juvenile idiopathic arthritis
    J M Burnham
    The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA
    J Musculoskelet Neuronal Interact 6:351-2. 2006
  7. ncbi Alterations in proximal femur geometry in children treated with glucocorticoids for Crohn disease or nephrotic syndrome: impact of the underlying disease
    Jon M Burnham
    The Children s Hospital of Philadelphia, Philadelphia PA 19104, USA
    J Bone Miner Res 22:551-9. 2007
    ..Subperiosteal width and section modulus were significantly lower in CD and greater in SSNS compared with controls, highlighting the importance of the underlying disease, persistent inflammation, and alterations in lean mass...
  8. ncbi Bone density, structure, and strength in juvenile idiopathic arthritis: importance of disease severity and muscle deficits
    Jon M Burnham
    Children s Hospital of Philadelphia, and University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Arthritis Rheum 58:2518-27. 2008
    ....
  9. ncbi Divergent effects of glucocorticoids on cortical and trabecular compartment BMD in childhood nephrotic syndrome
    Rachel J Wetzsteon
    Department of Pediatrics, Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
    J Bone Miner Res 24:503-13. 2009
    ..Lower bone biomarkers were associated with greater cortical vBMD. Studies are needed to determine the fracture implications of these varied effects...
  10. ncbi Determinants of changes in linear growth and body composition in incident pediatric Crohn's disease
    Meena Thayu
    Department of Pediatrics, The Children s Hospital of Philadelphia, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    Gastroenterology 139:430-8. 2010
    ..Pediatric Crohn's disease (CD) is associated with growth, lean mass (LM), and fat mass (FM) deficits. This study assessed and identified determinants of changes in height and body composition in children with CD following...
  11. ncbi Effects of sex, race, and puberty on cortical bone and the functional muscle bone unit in children, adolescents, and young adults
    Mary B Leonard
    Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
    J Clin Endocrinol Metab 95:1681-9. 2010
    ..Sex and race differences in bone development are associated with differences in growth, maturation, and body composition...
  12. ncbi Variation in inpatient therapy and diagnostic evaluation of children with Henoch Schönlein purpura
    Pamela F Weiss
    Division of Rheumatology, The Children s Hospital of Philadelphia, Philadelphia, PA, USA
    J Pediatr 155:812-818.e1. 2009
    ..To describe variation regarding inpatient therapy and evaluation of children with Henoch Schönlein purpura (HSP) admitted to children's hospitals across the United States...
  13. ncbi Hypovitaminosis D is associated with greater body mass index and disease activity in pediatric systemic lupus erythematosus
    Tracey B Wright
    Department of Pediatrics, Division of Rheumatology, University of Texas Southwestern Medical Center, Dallas, TX, USA
    J Pediatr 155:260-5. 2009
    ..To determine whether pediatric systemic lupus erythematosus (SLE) is associated with alterations in the vitamin D-parathyroid hormone (PTH) axis and to assess the relation between vitamin D deficiency and SLE activity...
  14. ncbi Corticosteroids may improve clinical outcomes during hospitalization for Henoch-Schönlein purpura
    Pamela F Weiss
    Division of Rheumatology, Children s Hospital of Philadelphia, and Department of Pediatrics, Center for Clinical Epidemiology and Biostatistics, Leonard Davis Institute of Health Economics, University of Pennsylvania School of Medicine, Room 1539, North Campus, 3535 Market St, Philadelphia, PA 19104, USA
    Pediatrics 126:674-81. 2010
    ..To characterize the effect of corticosteroid exposure on clinical outcomes in children hospitalized with new-onset Henoch-Schönlein purpura (HSP)...
  15. ncbi Longitudinal assessment of bone density and structure in an incident cohort of children with Crohn's disease
    Sarah E Dubner
    Department of Pediatrics, Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
    Gastroenterology 136:123-30. 2009
    ..The objective of this longitudinal study was to assess musculoskeletal outcomes in an incident cohort of children with CD using peripheral quantitative computed tomography (pQCT)...
  16. ncbi Interpretation of biomarkers of bone metabolism in children: impact of growth velocity and body size in healthy children and chronic disease
    Shamir Tuchman
    Department of Pediatrics, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    J Pediatr 153:484-90. 2008
    ....
  17. ncbi Effects of corticosteroid on Henoch-Schönlein purpura: a systematic review
    Pamela F Weiss
    Division of Rheumatology, Children s Hospital of Philadelphia, Children s Seashore House Room 236, 34th and Civic Center Boulevard, Philadelphia, PA 19104 4399, USA
    Pediatrics 120:1079-87. 2007
    ..Therefore, we sought to synthesize the reported experimental and observational data regarding corticosteroid use...
  18. ncbi Gender differences in body composition deficits at diagnosis in children and adolescents with Crohn's disease
    Meena Thayu
    Children s Hospital of Philadelphia Gastroenterology, Hepatology, and Nutrition, Philadelphia, Pennsylvania 19104, USA
    Inflamm Bowel Dis 13:1121-8. 2007
    ..Objectives: To quantify LM and FM in incident pediatric CD subjects and controls, and to identify determinants of LM and FM deficits...
  19. ncbi HIV infection presenting as severe autoimmune hemolytic anemia with disseminated intravascular coagulation in an infant
    Susan R Rheingold
    Divisions of Oncology, Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    J Pediatr Hematol Oncol 26:9-12. 2004
    ..The authors describe a 5-month-old infant who presented with severe autoimmune hemolytic anemia and disseminated intravascular coagulation as his initial manifestation of HIV infection...
  20. ncbi Assessment of spine bone mineral density in juvenile idiopathic arthritis: impact of scan projection
    Sarah E Dubner
    University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    J Clin Densitom 11:302-8. 2008
    ..In conclusion, WA-BMD may be more sensitive to disease effects in children because it selectively measures the trabecular-rich vertebral body and is independent of growth-related changes in BMC of the dense spinous processes...
  21. ncbi Bone disease in pediatric rheumatologic disorders
    Jon M Burnham
    Department of Pediatrics, The Children's Hospital of Philadelphia, 34th Street and Civic Center Boulevard, CHOP North, Room 1564, Philadelphia, PA 19104, USA
    Curr Rheumatol Rep 6:70-8. 2004
    ..Finally, future research directions are proposed...
  22. ncbi Variation in the initial treatment of knee monoarthritis in juvenile idiopathic arthritis: a survey of pediatric rheumatologists in the United States and Canada
    Timothy Beukelman
    Department of Pediatrics, Division of Rheumatology and Division of General Pediatrics, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
    J Rheumatol 34:1918-24. 2007
    ....

Research Grants2

  1. The Functional Muscle-Bone Unit in JRA
    Jon Burnham; Fiscal Year: 2007
    ..Completion of this study will provide the applicant with the data and experience needed to support subsequent independent proposals to improve musculoskeletal health in this high-risk population. ..