Arthur Burghes

Summary

Affiliation: The Ohio State University
Country: USA

Publications

  1. pmc SMA-EUROPE workshop report: opportunities and challenges in developing clinical trials for spinal muscular atrophy in Europe
    Nathalie Kayadjanian
    TransBioMed solutions LLC, Murray Hill, USA
    Orphanet J Rare Dis 8:44. 2013
  2. pmc Generation and Characterization of a genetic zebrafish model of SMA carrying the human SMN2 gene
    Le T Hao
    Dept of Neuroscience and Center for Molecular Neurobiology, The Ohio State University, 1060 Carmack Rd, Columbus OH 43210, USA
    Mol Neurodegener 6:24. 2011
  3. pmc Absence of gemin5 from SMN complexes in nuclear Cajal bodies
    Le Thi Hao
    Wolfson Centre for Inherited Neuromuscular Disease, RJAH Orthopaedic Hospital, Oswestry, UK
    BMC Cell Biol 8:28. 2007
  4. ncbi request reprint Other forms of survival motor neuron protein and spinal muscular atrophy: an opinion
    H M Burghes
    Department of Molecular and Cellular Biochemistry, Ohio State University, Columbus, OH 43210, United States
    Neuromuscul Disord 18:82-3. 2008
  5. pmc Spinal muscular atrophy: why do low levels of survival motor neuron protein make motor neurons sick?
    Arthur H M Burghes
    Department of Molecular and Cellular Biochemistry, The Ohio State University, Columbus, Ohio 43210, USA
    Nat Rev Neurosci 10:597-609. 2009
  6. pmc Antisense oligonucleotides and spinal muscular atrophy: skipping along
    Arthur H M Burghes
    Department of Molecular and Cellular Biochemistry, The Ohio State University, Columbus, Ohio 43210, USA
    Genes Dev 24:1574-9. 2010
  7. pmc Indoprofen upregulates the survival motor neuron protein through a cyclooxygenase-independent mechanism
    Mitchell R Lunn
    Department of Biological Sciences, Columbia University, Fairchild Center, MC 2406, 1212 Amsterdam Avenue, New York, NY 10027, USA
    Chem Biol 11:1489-93. 2004

Collaborators

  • C J Sumner
  • Nathalie Kayadjanian
  • Le T Hao
  • H M Burghes
  • Le Thi Hao
  • Glenn E Morris
  • Mitchell R Lunn
  • Francoise Rouault
  • Eugenio Mercuri
  • Kevin Talbot
  • Inge Schwersenz
  • Richard S Finkel
  • Christine E Beattie
  • Le Thanh Lam
  • Heidi R Fuller
  • Thanh T Le
  • Daniel D Coovert
  • David E Root
  • Jianhua Zhou
  • Nguyen Thi Man
  • Stephen P Flaherty
  • Brent R Stockwell
  • Brian P Kelley
  • Elliot J Androphy
  • Allison M Martino

Detail Information

Publications7

  1. pmc SMA-EUROPE workshop report: opportunities and challenges in developing clinical trials for spinal muscular atrophy in Europe
    Nathalie Kayadjanian
    TransBioMed solutions LLC, Murray Hill, USA
    Orphanet J Rare Dis 8:44. 2013
    ....
  2. pmc Generation and Characterization of a genetic zebrafish model of SMA carrying the human SMN2 gene
    Le T Hao
    Dept of Neuroscience and Center for Molecular Neurobiology, The Ohio State University, 1060 Carmack Rd, Columbus OH 43210, USA
    Mol Neurodegener 6:24. 2011
    ..abstract:..
  3. pmc Absence of gemin5 from SMN complexes in nuclear Cajal bodies
    Le Thi Hao
    Wolfson Centre for Inherited Neuromuscular Disease, RJAH Orthopaedic Hospital, Oswestry, UK
    BMC Cell Biol 8:28. 2007
    ..These complexes are involved in the assembly of snRNPs in the cytoplasm and their transport into the nucleus, but the precise roles of the individual protein components are largely unknown...
  4. ncbi request reprint Other forms of survival motor neuron protein and spinal muscular atrophy: an opinion
    H M Burghes
    Department of Molecular and Cellular Biochemistry, Ohio State University, Columbus, OH 43210, United States
    Neuromuscul Disord 18:82-3. 2008
  5. pmc Spinal muscular atrophy: why do low levels of survival motor neuron protein make motor neurons sick?
    Arthur H M Burghes
    Department of Molecular and Cellular Biochemistry, The Ohio State University, Columbus, Ohio 43210, USA
    Nat Rev Neurosci 10:597-609. 2009
    ..The second hypothesis proposes that SMN is crucial for the transport of mRNA in neurons and that disruption of this function results in SMA...
  6. pmc Antisense oligonucleotides and spinal muscular atrophy: skipping along
    Arthur H M Burghes
    Department of Molecular and Cellular Biochemistry, The Ohio State University, Columbus, Ohio 43210, USA
    Genes Dev 24:1574-9. 2010
    ....
  7. pmc Indoprofen upregulates the survival motor neuron protein through a cyclooxygenase-independent mechanism
    Mitchell R Lunn
    Department of Biological Sciences, Columbia University, Fairchild Center, MC 2406, 1212 Amsterdam Avenue, New York, NY 10027, USA
    Chem Biol 11:1489-93. 2004
    ..No other NSAIDs or COX inhibitors tested exhibited this activity...