Karen Bulloch

Summary

Affiliation: The Rockefeller University
Country: USA

Publications

  1. doi CD11c/EYFP transgene illuminates a discrete network of dendritic cells within the embryonic, neonatal, adult, and injured mouse brain
    Karen Bulloch
    Laboratory of Cellular Physiology and Immunology, The Rockefeller University, New York, New York 10065, USA
    J Comp Neurol 508:687-710. 2008
  2. doi Accumulation of resident and peripheral dendritic cells in the aging CNS
    Ulrike W Kaunzner
    Laboratory of Neuroendocrinology, The Rockefeller University, New York, NY 10065, USA
    Neurobiol Aging 33:681-693.e1. 2012
  3. doi Steroid hormone receptor expression and function in microglia
    Amanda Sierra
    Laboratory of Neuroendocrinology, Rockefeller University, New York, New York 10021, USA
    Glia 56:659-74. 2008
  4. pmc Acute in vivo exposure to interferon-gamma enables resident brain dendritic cells to become effective antigen presenting cells
    Andres Gottfried-Blackmore
    Laboratory of Neuroendocrinology, The Rockefeller University, New York, NY 10065, USA
    Proc Natl Acad Sci U S A 106:20918-23. 2009
  5. pmc Brain dendritic cells in ischemic stroke: time course, activation state, and origin
    Jennifer C Felger
    Laboratory of Neuroendocrinology, The Rockefeller University, New York, NY 10065, USA
    Brain Behav Immun 24:724-37. 2010
  6. doi 7α-hydroxylation of dehydroepiandrosterone does not interfere with the activation of glucocorticoids by 11β-hydroxysteroid dehydrogenase in E(t)C cerebellar neurons
    Andres Gottfried-Blackmore
    Harold and Margaret Milliken Hatch, Laboratory of Neuroendocrinology, The Rockefeller University, 1230 York Avenue, New York, NY 10065, USA
    J Steroid Biochem Mol Biol 138:290-7. 2013
  7. doi Microglia express functional 11 beta-hydroxysteroid dehydrogenase type 1
    Andres Gottfried-Blackmore
    Laboratory of Neuroendocrinology, Rockefeller University, New York, New York 10065, USA
    Glia 58:1257-66. 2010
  8. ncbi Transcriptional activity of estrogen receptors ERalpha and ERbeta in the EtC.1 cerebellar granule cell line
    Andres Gottfried-Blackmore
    Laboratory of Neuroendocrinology, The Rockefeller University, 1230 York Avenue, New York, NY, USA
    Brain Res 1186:41-7. 2007
  9. pmc Brain dendritic cells: biology and pathology
    Paul M D'Agostino
    The Laboratory of Neuroendocrinology, The Rockefeller University, New York, NY 10065, USA
    Acta Neuropathol 124:599-614. 2012
  10. pmc Viral-induced encephalitis initiates distinct and functional CD103+ CD11b+ brain dendritic cell populations within the olfactory bulb
    Paul M D'Agostino
    Laboratory of Neuroendocrinology, The Rockefeller University, New York, NY 10065, USA
    Proc Natl Acad Sci U S A 109:6175-80. 2012

Collaborators

  • Teresa A Milner
  • Elizabeth M Waters
  • Kang Liu
  • Takato Abe
  • Costantino Iadecola
  • R M Steinman
  • Andres Gottfried-Blackmore
  • Bruce S McEwen
  • Amanda Sierra
  • Paul M D'Agostino
  • Ulrike W Kaunzner
  • Jennifer C Felger
  • Peter H Jellinck
  • Zahrah Masheeb
  • Haley A Vecchiarelli
  • Judit Gal-Toth
  • Gist Croft
  • Anisha Patel
  • Martin Kaufmann
  • Niroshana Anandasabapathy
  • James M Miller
  • Judit Gal Toth
  • Melinda M Miller
  • Changsoo Kwak
  • Renshan Ge
  • Juliana Idoyaga
  • Andres C Gottfried-Blackmore
  • Janet Clark

Detail Information

Publications14

  1. doi CD11c/EYFP transgene illuminates a discrete network of dendritic cells within the embryonic, neonatal, adult, and injured mouse brain
    Karen Bulloch
    Laboratory of Cellular Physiology and Immunology, The Rockefeller University, New York, New York 10065, USA
    J Comp Neurol 508:687-710. 2008
    ..Collectively, these findings suggest a new member of the dendritic cell family residing among the heterogeneous microglia population...
  2. doi Accumulation of resident and peripheral dendritic cells in the aging CNS
    Ulrike W Kaunzner
    Laboratory of Neuroendocrinology, The Rockefeller University, New York, NY 10065, USA
    Neurobiol Aging 33:681-693.e1. 2012
    ..Collectively, the numerical and phenotypic changes in bDC indicate these cells may serve as an important immune component in the functional and anatomic alterations associated with aging...
  3. doi Steroid hormone receptor expression and function in microglia
    Amanda Sierra
    Laboratory of Neuroendocrinology, Rockefeller University, New York, New York 10021, USA
    Glia 56:659-74. 2008
    ....
  4. pmc Acute in vivo exposure to interferon-gamma enables resident brain dendritic cells to become effective antigen presenting cells
    Andres Gottfried-Blackmore
    Laboratory of Neuroendocrinology, The Rockefeller University, New York, NY 10065, USA
    Proc Natl Acad Sci U S A 106:20918-23. 2009
    ..Activated bDC were also able to stimulate naïve CD8 T cells. Collectively, these data reveal the Th1 cytokine IFNgamma, but not the Th2 cytokine IL4, induces bDC to up-regulate MHC-II and become competent APC...
  5. pmc Brain dendritic cells in ischemic stroke: time course, activation state, and origin
    Jennifer C Felger
    Laboratory of Neuroendocrinology, The Rockefeller University, New York, NY 10065, USA
    Brain Behav Immun 24:724-37. 2010
    ..High levels of MHC II and the co-stimulatory molecule CD80 on bDC at 72 h corresponded to peak lymphocyte infiltration, and suggested a functional interaction between these two immune cell populations...
  6. doi 7α-hydroxylation of dehydroepiandrosterone does not interfere with the activation of glucocorticoids by 11β-hydroxysteroid dehydrogenase in E(t)C cerebellar neurons
    Andres Gottfried-Blackmore
    Harold and Margaret Milliken Hatch, Laboratory of Neuroendocrinology, The Rockefeller University, 1230 York Avenue, New York, NY 10065, USA
    J Steroid Biochem Mol Biol 138:290-7. 2013
    ..Our investigation on the metabolism of DHEA in E(t)C neuronal cells suggest that other alternate mechanisms must be at play to explain the in vivo anti-glucocorticoid properties of DHEA and its 7-OH-metabolites. ..
  7. doi Microglia express functional 11 beta-hydroxysteroid dehydrogenase type 1
    Andres Gottfried-Blackmore
    Laboratory of Neuroendocrinology, Rockefeller University, New York, New York 10065, USA
    Glia 58:1257-66. 2010
    ..We propose that 11 beta HSD-1 may provide microglia with an intrinsic mechanism to autoregulate and inhibit proinflammatory mediator production through CORT formation...
  8. ncbi Transcriptional activity of estrogen receptors ERalpha and ERbeta in the EtC.1 cerebellar granule cell line
    Andres Gottfried-Blackmore
    Laboratory of Neuroendocrinology, The Rockefeller University, 1230 York Avenue, New York, NY, USA
    Brain Res 1186:41-7. 2007
    ..The data suggest that ERalpha plays a predominant role in E2-mediated transcription in E(t)C.1 cells. Our data are discussed in view of other reports alluding to the complexity and cell-type specificity of E2-mediated transcription...
  9. pmc Brain dendritic cells: biology and pathology
    Paul M D'Agostino
    The Laboratory of Neuroendocrinology, The Rockefeller University, New York, NY 10065, USA
    Acta Neuropathol 124:599-614. 2012
    ....
  10. pmc Viral-induced encephalitis initiates distinct and functional CD103+ CD11b+ brain dendritic cell populations within the olfactory bulb
    Paul M D'Agostino
    Laboratory of Neuroendocrinology, The Rockefeller University, New York, NY 10065, USA
    Proc Natl Acad Sci U S A 109:6175-80. 2012
    ..Finally, each EYFP(+) population contained CD11b(+) CD103(+) subpopulations and could be distinguished in terms of CD115, Gr-1, and Ly-6C expression, highlighting mucosal and monocyte-derived DC lineages...
  11. ncbi Characterization of a cerebellar granule progenitor cell line, EtC.1, and its responsiveness to 17-beta-estradiol
    Andres Gottfried-Blackmore
    Laboratory of Neuroendocrinology, The Rockefeller University, 1230 York Avenue, New York, NY 10065, USA
    Brain Res 1186:29-40. 2007
    ..Collectively, our results show that the E(t)C.1 cell line may serve as a model to study early development of cerebellar progenitor granule cells, and their responsiveness to E2...
  12. ncbi Microglia derived from aging mice exhibit an altered inflammatory profile
    Amanda Sierra
    Laboratory of Neuroendocrinology, Rockefeller University, New York, NY, USA
    Glia 55:412-24. 2007
    ..Gender differences were not overall observed across the treatments (age, LPS). The low but sustained production of pro-inflammatory cytokines by aging microglia may have a profound impact in the brain aging process...
  13. ncbi Type II glucocorticoid receptor immunoreactivity in the mossy cells of the rat and the mouse hippocampus
    Anisha Patel
    Laboratory of Neuroendocrinology, Rockefeller University, New York, New York 10021, USA
    Hippocampus 13:59-66. 2003
    ..The presence of GR on mossy cells may indicate the ability of GC to mediate cellular activity of these cells...
  14. pmc Brain microglia express steroid-converting enzymes in the mouse
    Andres Gottfried-Blackmore
    Laboratory of Neuroendocrinology, Rockefeller University, 1230 York Avenue, New York, NY 10065, United States
    J Steroid Biochem Mol Biol 109:96-107. 2008
    ..Collectively, our results suggest that microglia utilize steroid-converting enzymes and related proteins to influence inflammation and neurodegeneration within microenvironments of the brain...