M Buck

Summary

Affiliation: The Salk Institute
Country: USA

Publications

  1. ncbi Phosphorylation of rat serine 105 or mouse threonine 217 in C/EBP beta is required for hepatocyte proliferation induced by TGF alpha
    M Buck
    Salk Institute for Biological Studies, La Jolla, California 92037, USA
    Mol Cell 4:1087-92. 1999
  2. ncbi C/EBPbeta phosphorylation by RSK creates a functional XEXD caspase inhibitory box critical for cell survival
    M Buck
    Molecular Biology and Virology Laboratory, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA
    Mol Cell 8:807-16. 2001
  3. ncbi Nuclear export of phosphorylated C/EBPbeta mediates the inhibition of albumin expression by TNF-alpha
    M Buck
    Molecular and Cell Biology Laboratory, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA
    EMBO J 20:6712-23. 2001
  4. ncbi LAP (NF-IL6) transactivates the collagen alpha 1(I) gene from a 5' regulatory region
    K Houglum
    Department of Medicine, Veterans Affairs Medical Center, San Diego, California
    J Clin Invest 94:808-14. 1994
  5. ncbi Nucleotide-dependent interactions between a fork junction-RNA polymerase complex and an AAA+ transcriptional activator protein
    W V Cannon
    Department of Biological Sciences, Sir Alexander Fleming Building, Imperial College London, South Kensington Campus, London SW7 2AZ, UK
    Nucleic Acids Res 32:4596-608. 2004
  6. ncbi Mechanochemical ATPases and transcriptional activation
    X Zhang
    Imperial College Centre for Structural Biology, Imperial College of Science, Technology and Medicine, London, UK
    Mol Microbiol 45:895-903. 2002
  7. ncbi The CRP-cAMP complex and downregulation of the glnAp2 promoter provides a novel regulatory linkage between carbon metabolism and nitrogen assimilation in Escherichia coli
    Z X Tian
    National Laboratory of Protein Engineering and Plant Genetic Engineering, College of Life Sciences, Peking University, Beijing 100871, People s Republic of China
    Mol Microbiol 41:911-24. 2001
  8. ncbi Regulatory sequences in sigma 54 localise near the start of DNA melting
    S R Wigneshweraraj
    Department of Biology, Imperial College of Science Technology and Medicine, Imperial College Road, London, SW7 2AZ, UK
    J Mol Biol 306:681-701. 2001
  9. ncbi In vitro roles of invariant helix-turn-helix motif residue R383 in sigma(54) (sigma(N))
    S R Wigneshweraraj
    Department of Biology, Imperial College of Science, Technology and Medicine, Sir Alexander Fleming Building, Imperial College Road, London SW7 2AZ, UK
    Nucleic Acids Res 29:1163-74. 2001
  10. ncbi DNA melting within a binary sigma(54)-promoter DNA complex
    W Cannon
    Department of Biology, Imperial College of Science, Technology and Medicine, London SW7 2AZ, United Kingdom
    J Biol Chem 276:386-94. 2001

Collaborators

  • T Hunter
  • L Zhang
  • S R Wigneshweraraj
  • W V Cannon
  • J Schumacher
  • X Zhang
  • W Cannon
  • P Bordes
  • Z X Tian
  • A Ishihama
  • M Rappas
  • R D Finn
  • P C Burrows
  • M Chaney
  • Siva R Wigneshweraraj
  • Y P Wang
  • M K Chaney
  • Q S Li
  • A Kolb
  • M T Gallegos
  • K Houglum
  • V Adir
  • M Chojkier

Detail Information

Publications12

  1. ncbi Phosphorylation of rat serine 105 or mouse threonine 217 in C/EBP beta is required for hepatocyte proliferation induced by TGF alpha
    M Buck
    Salk Institute for Biological Studies, La Jolla, California 92037, USA
    Mol Cell 4:1087-92. 1999
    ..Thus, a site-specific phosphorylation of the transcription factor C/EBP beta is critical for hepatocyte proliferation induced by TGF alpha and other stimuli that activate RSK...
  2. ncbi C/EBPbeta phosphorylation by RSK creates a functional XEXD caspase inhibitory box critical for cell survival
    M Buck
    Molecular Biology and Virology Laboratory, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA
    Mol Cell 8:807-16. 2001
    ..C/EBPbeta-/- and C/EBPbeta-Ala(217) stellate cells were rescued from apoptosis by the cell permeant KE(217)VD tetrapeptide or C/EBPbeta-Glu(217)...
  3. ncbi Nuclear export of phosphorylated C/EBPbeta mediates the inhibition of albumin expression by TNF-alpha
    M Buck
    Molecular and Cell Biology Laboratory, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA
    EMBO J 20:6712-23. 2001
    ..Treatment of TNF-alpha mice with antioxidants or NOS inhibitors prevented phosphorylation of C/EBPbeta on Ser239 and its nuclear export, and rescued the abnormal albumin gene expression...
  4. ncbi LAP (NF-IL6) transactivates the collagen alpha 1(I) gene from a 5' regulatory region
    K Houglum
    Department of Medicine, Veterans Affairs Medical Center, San Diego, California
    J Clin Invest 94:808-14. 1994
    ..These experiments suggest that LAP may be important in the expression of collagen in differentiated hepatocytes through both the promoter and a newly described upstream element...
  5. ncbi Nucleotide-dependent interactions between a fork junction-RNA polymerase complex and an AAA+ transcriptional activator protein
    W V Cannon
    Department of Biological Sciences, Sir Alexander Fleming Building, Imperial College London, South Kensington Campus, London SW7 2AZ, UK
    Nucleic Acids Res 32:4596-608. 2004
    ..We also provide evidence for two distinct closed promoter complexes with differing stabilities...
  6. ncbi Mechanochemical ATPases and transcriptional activation
    X Zhang
    Imperial College Centre for Structural Biology, Imperial College of Science, Technology and Medicine, London, UK
    Mol Microbiol 45:895-903. 2002
    ..In particular, interprotomer ATP interactions rely upon the use of an arginine finger, a situation reminiscent of GTPase-activating proteins...
  7. ncbi The CRP-cAMP complex and downregulation of the glnAp2 promoter provides a novel regulatory linkage between carbon metabolism and nitrogen assimilation in Escherichia coli
    Z X Tian
    National Laboratory of Protein Engineering and Plant Genetic Engineering, College of Life Sciences, Peking University, Beijing 100871, People s Republic of China
    Mol Microbiol 41:911-24. 2001
    ..A novel regulatory linkage between carbon and nitrogen regulons is proposed...
  8. ncbi Regulatory sequences in sigma 54 localise near the start of DNA melting
    S R Wigneshweraraj
    Department of Biology, Imperial College of Science Technology and Medicine, Imperial College Road, London, SW7 2AZ, UK
    J Mol Biol 306:681-701. 2001
    ..This contrasts systems where activators recruit RNA polymerase to promoter DNA, and the protein and DNA determinants required for activation localise away from promoter sequences closely associated with the start of DNA melting...
  9. ncbi In vitro roles of invariant helix-turn-helix motif residue R383 in sigma(54) (sigma(N))
    S R Wigneshweraraj
    Department of Biology, Imperial College of Science, Technology and Medicine, Sir Alexander Fleming Building, Imperial College Road, London SW7 2AZ, UK
    Nucleic Acids Res 29:1163-74. 2001
    ..R383 contributes to several properties, including core RNA polymerase binding and to the in vivo stability of sigma(54)...
  10. ncbi DNA melting within a binary sigma(54)-promoter DNA complex
    W Cannon
    Department of Biology, Imperial College of Science, Technology and Medicine, London SW7 2AZ, United Kingdom
    J Biol Chem 276:386-94. 2001
    ....
  11. ncbi The bacterial enhancer-dependent sigma(54) (sigma(N)) transcription factor
    M Buck
    Department of Biology, Imperial College of Science, Technology and Medicine, London SW7 2AZ, United Kingdom
    J Bacteriol 182:4129-36. 2000
  12. ncbi The second paradigm for activation of transcription
    S R Wigneshweraraj
    Department of Biological Sciences and Centre for Structural Biology, Imperial College London, London SW7 2AZ, United Kingdom
    Prog Nucleic Acid Res Mol Biol 79:339-69. 2005