Research Topics
Genomes and GenesSpecies | E BrueraSummaryAffiliation: The University of Texas Country: USA Publications
| Collaborators
|
Detail Information
Publications
Cachexia and asthenia in cancer patientsE Bruera
Department of Symptom Control and Palliative Care, University of Texas M D Anderson Cancer Center, Houston 77030, USA
Lancet Oncol 1:138-47. 2000..Future research should clarify optimum management. The way forward seems to lie in a multidimensional approach with combined therapy to manage both cancer cachexia and asthenia...
Effect of fish oil on appetite and other symptoms in patients with advanced cancer and anorexia/cachexia: a double-blind, placebo-controlled studyEduardo Bruera
Department of Palliative Care and Rehabilitation Medicine, The University of Texas M D Anderson Cancer Center, Houston, TX 77030 0049, USA
J Clin Oncol 21:129-34. 2003..To determine whether high doses of fish oil, administered over 2 weeks, improve symptoms in patients with advanced cancer and decreased weight and appetite...
Patient-controlled methylphenidate for cancer fatigue: a double-blind, randomized, placebo-controlled trialEduardo Bruera
Department of Palliative Care and Rehabilitation Medicine, Unit 0008, The University of Texas M D Anderson Cancer Center, Houston, TX 77030 4009, USA
J Clin Oncol 24:2073-8. 2006..To evaluate the effectiveness of patient-controlled methylphenidate as compared with placebo in cancer patients with fatigue, as measured by the Functional Assessment for Chronic Illness Therapy-Fatigue (FACIT-F)...
Methadone versus morphine as a first-line strong opioid for cancer pain: a randomized, double-blind studyEduardo Bruera
Department of Palliative Care and Rehabilitation Medicine Unit 0008, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030 0049, USA
J Clin Oncol 22:185-92. 2004..To compare the effectiveness and side effects of methadone and morphine as first-line treatment with opioids for cancer pain...
Patient preferences versus physician perceptions of treatment decisions in cancer careE Bruera
Department of Symptom Control and Palliative Care, University of Texas, M D Anderson Cancer Center, Houston, TX 77030, USA
J Clin Oncol 19:2883-5. 2001..To examine patient preferences as well as physician perceptions of these preferences for decision making and communication in palliative care...
Fatigue in patients with advanced cancer: a reviewE A Barnes
Department of Palliative Care and Rehabilitation Medicine, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
Int J Gynecol Cancer 12:424-8. 2002..Pharmacologic agents that have been investigated for use in treating fatigue include corticosteroids, progestational agents, and psychostimulants. Agents that modulate cytokine activity are future treatment possibilities...
Pharmacologic management of nonpain symptoms in surgical patientsE Bruera
Department of Symptom Control and Palliative Care, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA
Surg Oncol Clin N Am 10:89-107. 2001..More research on the mechanism and treatment of these symptoms is needed...
Research opportunities in palliative medicineC Sweeney
Department of Symptom Control and Palliative Care, University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Blvd, Box 008, Houston, TX 77030, USA
Tex Med 97:64-8. 2001..Methodological challenges in patient issues and trial design are outlined, and areas for future research are proposed...
Legislation analysis according to WHO and INCB criteria on opioid availability: a comparative study of 5 countries and the state of TexasM H Liliana De Lima
WHO PAHO Liaison in Supportive Care, University of Texas, MD Anderson Cancer Center, Houston, TX 77030, USA
Health Policy 56:99-110. 2001..Such review seeks to carefully consider all possible criteria, since partial resolution of legislative articles will not result in increased opioid availability...
A phase III randomized, double-blind, placebo-controlled study evaluating dextromethorphan plus slow-release morphine for chronic cancer pain relief in terminally ill patientsDeborah J Dudgeon
Palliative Care Medicine, Queen s University, Kingston, Ontario, Canada
J Pain Symptom Manage 33:365-71. 2007..Participants receiving the DM also had more toxicity, particularly dizziness. This toxicity and the limited evidence of effect do not support the use of DM to enhance opioid analgesia or to modulate opioid tolerance in cancer patients...
Palliative sedation: when the family and consulting service see no alternativeEgidio Del Fabbro
Department of Palliative Care and Rehabilitation Medicine, The University of Texas, M.D. Anderson Cancer Center, Houston, Texas 77030, USA
J Palliat Med 10:488-92. 2007
Evaluation and pharmacologic management of symptoms in cancer patients undergoing acute rehabilitation in a comprehensive cancer centerYing Guo
Department of Palliative Care and Rehabilitation Medicine, University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
Arch Phys Med Rehabil 88:891-5. 2007..To identify cancer patients' symptoms at admission and on discharge from an acute rehabilitation unit, to document the discharge medications used for symptom management, and to assess how symptoms affect lengths of stay (LOS)...
High-dose corticosteroids for the management of dyspnea in patients with tumor obstruction of the upper airwayAhmed Elsayem
UT M. D. Anderson Cancer Center, P.O. Box 008, 1515 Holcombe Boulevard, Houston, TX 77030-4095, USA
Support Care Cancer 15:1437-9. 2007
Managing cancer-related symptoms: advances in supportive oncologyEduardo Bruera
Professor, Palliative Care and Rehabilitation Medicine, The University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA
Clin Adv Hematol Oncol 5:29-31. 2007
The impact of the palliative care mobile team on symptom assessment and medication profiles in patients admitted to a comprehensive cancer centerSriram Yennurajalingam
Department of Palliative Care and Rehabilitation Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
Support Care Cancer 15:471-5. 2007..However, the availability of such information is limited. The purpose of our study was therefore to describe the experience of a palliative care team at our comprehensive cancer center...
Palliative care. Clinical practice guidelines in oncologyMichael H Levy
Fox Chase Cancer Center
J Natl Compr Canc Netw 4:776-818. 2006
Impact of a palliative care service on in-hospital mortality in a comprehensive cancer centerAhmed Elsayem
Department of Palliative Care and Rehabilitation Medicine, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
J Palliat Med 9:894-902. 2006..These services are not available in many cancer centers and tertiary hospitals. The purpose of this study was to review the impact of a palliative care program, established in 1999, on overall in-hospital mortality...
Critical issues on opioids in chronic non-cancer pain: an epidemiological studyJørgen Eriksen
Multidisciplinary Pain Centre, H S Rigshospitalet, Copenhagen, Denmark
Pain 125:172-9. 2006..However, it is remarkable that opioid treatment of long-term/chronic non-cancer pain does not seem to fulfil any of the key outcome opioid treatment goals: pain relief, improved quality of life and improved functional capacity...
Effects of parenteral hydration in terminally ill cancer patients: a preliminary studyEduardo Bruera
Department of Palliative Care and Rehabilitation Medicine, Unit 8, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
J Clin Oncol 23:2366-71. 2005..Most patients with cancer develop decreased oral intake and dehydration before death. This study aimed to determine the effect of parenteral hydration on overall symptom control in terminally ill cancer patients with dehydration...
Symptom control in palliative care--Part II: cachexia/anorexia and fatigueEgidio Del Fabbro
Department of Palliative Care and Rehabilitation Medicine, University of Texas MD Anderson Cancer Center, Houston, 77030, USA
J Palliat Med 9:409-21. 2006
Opioid switching: a systematic and critical reviewSebastiano Mercadante
Pain Relief and Palliative Care Unit, La Maddalena Cancer Center, Via San Lorenzo 312, 90146 Palermo, Italy
Cancer Treat Rev 32:304-15. 2006..The process of reaching an optimal dose should be highly individualized, particularly when patients are switched from high doses of opioids, given the wide conversion ratios reported in literature...
Prescribing patterns and purchasing costs of long-acting opioids over nine years at an academic oncology hospitalEardie A Curry
Department of Department of Drug Use Policy and Pharmacoeconomics, M D Anderson Cancer Center, Houston, TX 77030, USA
Am J Health Syst Pharm 64:1619-25. 2007..The prescribing patterns and purchasing costs of long-acting opioids over nine years at an academic oncology hospital were studied...
Association between megestrol acetate treatment and symptomatic adrenal insufficiency with hypogonadism in male patients with cancerRony Dev
Department of Palliative Care and Rehabilitation Medicine, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030 4009, USA
Cancer 110:1173-7. 2007..Clinicians need an increased awareness of the complication of adrenal insufficiency secondary to MA treatment and a low threshold to test for adrenal and gonadal dysfunction in symptomatic male patients with advanced cancer...
Donepezil for cancer fatigue: a double-blind, randomized, placebo-controlled trialEduardo Bruera
Department of Palliative Care and Rehabilitation Medicine, Unit 008, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
J Clin Oncol 25:3475-81. 2007..To evaluate the effectiveness of donepezil compared with placebo in cancer patients with fatigue as measured by the Functional Assessment for Chronic Illness Therapy-Fatigue (FACIT-F)...
Molecular epidemiology, cancer-related symptoms, and cytokines pathwayCielito C Reyes-Gibby
Department of Epidemiology, Division of Cancer Prevention and Population Sciences, The University of Texas, MD Anderson Cancer Center, Houston, TX 77030 4009, USA
Lancet Oncol 9:777-85. 2008..Likewise, they could identify subgroups who might benefit most from symptom intervention, and contribute to developing personalized and more effective therapies for persistent symptoms...
Incidence of and risk factors for transferring cancer patients from rehabilitation to acute care unitsYing Guo
Department of Palliative Care and Rehabilitation Medicine, University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
Am J Phys Med Rehabil 87:647-53. 2008..The aim of this study was to examine the clinical factors associated with transfer from an acute inpatient rehabilitation service to an inpatient oncology service...
Managing high dose sufentanil in a suffering patientPaul W Walker
J Pain Symptom Manage 36:e1-4. 2008
A randomized double-blind crossover comparison of continuous and intermittent subcutaneous administration of opioid for cancer painSharon Watanabe
Department of Symptom Control and Palliative Care, Cross Cancer Institute, Edmonton, Alberta, Canada
J Palliat Med 11:570-4. 2008..In all cases, patients and investigators expressed no preference for one modality over another. Further research is required to confirm that opioid administration by CSCI and ISCI provide similar analgesic and adverse effects...
On third base but not home yetEduardo Bruera
University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA
J Palliat Med 11:565-9. 2008
Management of pain in the older person with cancer. Part 2: treatment optionsMarvin Omar Delgado-Guay
The University of Texas M D Anderson Cancer Center, Houston, Texas 77030 4009, USA
Oncology (Williston Park) 22:148-52; discussion 152, 155, 160 passim. 2008..In this two-part article, the authors present a review of the management of pain in older cancer patients, emphasizing the roles of adequate assessment and a multidisciplinary team approach...
Interval between first palliative care consult and death in patients diagnosed with advanced cancer at a comprehensive cancer centerBadi El Osta
Department of Palliative Care and Rehabilitation Medicine, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
J Palliat Med 11:51-7. 2008....
Expressive writing in patients receiving palliative care: a feasibility studyEduardo Bruera
Palliative Care and Rehabilitation Medicine, M D Anderson Cancer Center, Houston, Texas 77030, USA
J Palliat Med 11:15-9. 2008..However, there are limited resources for psychological and emotional support. Expressive writing has shown decreased anxiety level in young and healthy people suffering from a number of stressors...
Comparison of symptom burden among patients referred to palliative care with hematologic malignancies versus those with solid tumorsNada A Fadul
Department of Palliative Care and Rehabilitation Medicine, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
J Palliat Med 11:422-7. 2008..The purposes of this retrospective study were to determine whether symptoms are less severe in patients with hematologic than in those with solid malignancies on APCS and whether symptom severity is associated with early APCS...
Cytokine genes and pain severity in lung cancer: exploring the influence of TNF-alpha-308 G/A IL6-174G/C and IL8-251T/ACielito C Reyes-Gibby
Department of Epidemiology, Division of Cancer Prevention, The University of Texas M D Anderson Cancer Center, Unit 1340, 1155 Pressler Street, Houston, TX 77030 4009, USA
Cancer Epidemiol Biomarkers Prev 16:2745-51. 2007..We explored if polymorphisms in candidate cytokine genes could explain variability in self-reported pain in lung cancer patients of all stages...
Clinically important improvement in the intensity of fatigue in patients with advanced cancerShantan Reddy
Department of Palliative Care and Rehabilitation Medicine, University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
J Palliat Med 10:1068-75. 2007..We were able to characterize the relationship between FACIT-F and ESAS scores and patients' global perception of improvement but further studies are needed to validate our findings...
A randomized, controlled trial of physician postures when breaking bad news to cancer patientsEduardo Bruera
Department of Palliative Care and Rehabilitation Medicine, MD Anderson Cancer Center, University of Texas, Houston, TX 77030, USA
Palliat Med 21:501-5. 2007..However, sitting posture alone is unlikely to compensate for poor communication skills and lack of other respectful gestures during a consultation...
Characteristics, findings, and outcomes of palliative care inpatient consultations at a comprehensive cancer centerFadi Braiteh
Department of Palliative Care and Rehabilitation Medicine, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030 4009, USA
J Palliat Med 10:948-55. 2007..The purpose of this retrospective chart review was to determine the characteristics, findings, and outcomes of patients referred to MT in a comprehensive cancer center and to thereby gain information about its role in this setting...
Parents dying of cancer and their childrenEstela A Beale
Department of Neuro Oncology, Psychiatry Section, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030 4095, USA
Palliat Support Care 2:387-93. 2004..These were the children of patients with terminal cancer referred to the Palliative Care and Symptom Control Service. In all cases the dying parent was a biological parent...
Dying patients and palliative sedationEgidio Del Fabbro
JAMA 295:1249-50; author reply 1250. 2006
Process and content of decision making by advanced cancer patientsEduardo Bruera
J Clin Oncol 24:1029-30. 2006
Changes in plasma levels of inflammatory cytokines in response to paclitaxel chemotherapyLajos Pusztai
Department of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
Cytokine 25:94-102. 2004..The objective of this study was to assess changes in plasma levels of interleukin (IL)-1beta, IL-6, IL-8, IL-10, IL-12, and TNF-alpha during chemotherapy and to correlate these changes with musculoskeletal symptoms...
A randomized controlled trial of supplemental oxygen versus air in cancer patients with dyspneaEduardo Bruera
Department of Palliative Care and Rehabilitation Medicine, Unit 8, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
Palliat Med 17:659-63. 2003..The symptomatic benefits of oxygen in patients with cancer who have nonhypoxic dyspnea are not well defined...
Patient-controlled methylphenidate for the management of fatigue in patients with advanced cancer: a preliminary reportEduardo Bruera
Department of Palliative Care and Rehabilitation Medicine, The University of Texas M D Anderson Cancer Center, Unit 8, 1515 Holcombe Blvd, Houston, TX 77030, USA
J Clin Oncol 21:4439-43. 2003..To assess the effects of patient-controlled methylphenidate for cancer-related fatigue...
Cancer painEduardo Bruera
Department of Palliative Care and Rehabilitation Medicine, University of Texas M. D. Anderson Cancer Center, Houston, Tex 77030, USA
JAMA 290:2476-9. 2003
Hypogonadism and sexual dysfunction in male cancer survivors receiving chronic opioid therapyArun Rajagopal
Department of Anesthesiology, University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA
J Pain Symptom Manage 26:1055-61. 2003..Given the increasing use of long-term opioid therapy for chronic pain syndromes, further investigation into these findings is warranted...
The effect of donepezil on sedation and other symptoms in patients receiving opioids for cancer pain: a pilot studyEduardo Bruera
Department of Palliative Care and Rehabilitation Medicine, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA
J Pain Symptom Manage 26:1049-54. 2003..Overall, however, the treatment was well tolerated. Donepezil appears to improve sedation and fatigue in patients receiving opioids for cancer pain. Randomized controlled trials of this agent are justified...
Use of a prone transfer technique in patients with severe hip-flexion restrictions: a report of 3 casesYing Guo
Department of Palliative Care and Rehabilitation Medicine, University of Texas, M D Anderson Cancer Center, Houston 77030, USA
Arch Phys Med Rehabil 84:912-4. 2003..Prone transfer may provide a low-cost, low-technologic way to mobilize patients with hip-flexion restriction...
Cannabinoids in supportive care: are they necessary?Eduardo Bruera
Support Care Cancer 11:133-4. 2003
Communication in cancer care: recent developmentsCatherine Sweeney
Department of Palliative Care and Rehabilitation Medicine, University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA
J Palliat Care 18:300-6. 2002
Heterotopic ossification in critical illness and cancer: a report of 2 casesYing Guo
Department of Symptom Control and Palliative Care, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
Arch Phys Med Rehabil 83:855-9. 2002..Serum alkaline phosphatase might be used as an effective screening tool...
Palliative care models: international perspectiveEduardo Bruera
Department of Symptom Control and Palliative Care, University of Texas, M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
J Palliat Med 5:319-27. 2002..Models of palliative care in three different countries are discussed and suggestions are made for the future development of palliative care in developing and developed countries...
Treatment decisions for breast carcinoma: patient preferences and physician perceptionsEduardo Bruera
Department of Palliative and Rehabilitation Medicine, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
Cancer 94:2076-80. 2002..The purpose of the current prospective study was to determine the agreement between patient decision-making preferences and physician perceptions of those preferences...
Palliative care inpatient service in a comprehensive cancer center: clinical and financial outcomesAhmed Elsayem
Department of Palliative Care and Rehabilitation Medicine, University of Texas M D Anderson Cancer Center, Houston, 77030, USA
J Clin Oncol 22:2008-14. 2004..The purpose of this article is to review the outcomes of the first 344 admissions to the Palliative Care Inpatient Service (PCIS) at our comprehensive cancer center...
Delirium in advanced cancer patientsCarlos Centeno
Centro Regional de Cuidados Paliativos y Tratamiento del Dolor, Hospital Los Montalvos, Salamanca, Spain
Palliat Med 18:184-94. 2004..Haloperidol is the most frequently used drug, and new neuroleptics such as risperidone or olanzapine are being tested with good results. Methylphenidate has been used for hypoactive delirium...
Oral methadone for cancer pain: no indication of Q-T interval prolongation or torsades de pointesSuresh Reddy
J Pain Symptom Manage 28:301-3. 2004
Symptom control and communication issues in advanced cervical cancerEduardo Bruera
M.D. Anderson Cancer Center, Palliative Care and Rehabilitative Medicine, 1515 Holcombe Blvd Unit 1330, Houston, TX 77030, USA
Gynecol Oncol 99:S219-20. 2005
Bowel and bladder continence, wound healing, and functional outcomes in patients who underwent sacrectomyYing Guo
Department of Palliative Care and Rehabilitation Medicine, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
J Neurosurg Spine 3:106-10. 2005..In this study the authors examined functional outcome following sacrectomy...
The association between anemia and fatigue in patients with advanced cancer receiving palliative careTina Noergaard Munch
Department of Palliative Care and Rehabilitation Medicine, The University of Texas M.D. Anderson Cancer Center, Houston, Texas 77030, USA
J Palliat Med 8:1144-9. 2005..0569). The overall explained variance for this model was 0.22. CONCLUSION: Our findings suggest that anemia is not one of the major contributors to fatigue in patients with cancer receiving palliative care...
Methadone-induced respiratory depression in a patient with a history of alcoholismAhmed Elsayem
Department of Palliative Care and Rehabilitation Medicine, The University of Texas M.D. Anderson Cancer Center, Houston, Texas
J Palliat Med 8:1062-6. 2005
Interval between palliative care referral and death among patients treated at a comprehensive cancer centerWen-Wu Cheng
Shanghai Cancer Hospital, Fudan University, China
J Palliat Med 8:1025-32. 2005..03). Our results should help palliative care and oncology programs at comprehensive cancer centers plan how to develop joint programs for patient care...
The clinical and research implications of survival predictionEduardo Bruera
Department of Palliative Care and Rehabilitation Medicine, University of Texas M. D. Anderson Cancer Center, Unit 008, 1515 Holcombe Blvd, Houston, TX 77030, USA
J Support Oncol 3:342, 348. 2005
Palliative pain management: when both pain and suffering hurtFlorian Strasser
Oncology and Palliative Medicine, Section Oncology/Hematology, Department of Internal Medicine, Cantonal Hospital, St. Gallen, Switzerland
J Palliat Care 21:69-79. 2005....
Cancer patients' perception of the quality of communication before and after the implementation of a communication strategy in a regional cancer center in IndiaSukdev Nayak
Palliative Care Unit, A.H. Regional Cancer Centre, Cuttack, India
J Clin Oncol 23:4771-5. 2005....
Impact of physician sitting versus standing during inpatient oncology consultations: patients' preference and perception of compassion and duration. A randomized controlled trialFlorian Strasser
Department of Palliative Care and Rehabilitation Medicine, The University of Texas M. D. Anderson Cancer Center, Houston, 77030, USA
J Pain Symptom Manage 29:489-97. 2005..Physicians should ask patients for their preference regarding physician sitting or standing as a way to enhance communication...
Clinical, sociodemographic, and local system factors associated with a hospital death among cancer patientsMarylou Cardenas-Turanzas
Section of Health Services Research, Department of Biostatistics and Applied Mathematics, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, P O Box 196, Houston, TX 77030 4009, USA
Support Care Cancer 14:71-7. 2006..The study was conducted to examine factors associated with hospital deaths among a group of cancer patients...
Pain and terminal delirium research in the elderlySriram Yennurajalingam
Department of Symptom Control and Palliative Care, University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 8, Houston, TX 77030-4095, USA
Clin Geriatr Med 21:93-119, viii. 2005..This article highlights new developments in assessment and management of pain and delirium...
Dexamethasone in addition to metoclopramide for chronic nausea in patients with advanced cancer: a randomized controlled trialEduardo Bruera
Department of Palliative Care and Rehabilitation Medicine, The University of Texas MD Anderson Cancer Center, Houston 77030, USA
J Pain Symptom Manage 28:381-8. 2004..Pain, vomiting, well-being, and quality of life remained unchanged in both groups at both times. We conclude that DM was not superior to placebo in the management of chronic nausea in our patients with advanced cancer...
Methadone use in cancer patients with pain: a reviewEduardo Bruera
Department of Symptom Control and Palliative Care, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030 0049, USA
J Palliat Med 5:127-38. 2002..In some patients with cancer the long half-life of methadone offers the advantage of extended dosing intervals to 12 and even 24 hours, further research is also needed in this area...
