Research Topics
Species | A M BrewsterSummaryAffiliation: The University of Texas Country: USA Publications
Research Grants
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Detail Information
Publications
Association between contralateral prophylactic mastectomy and breast cancer outcomes by hormone receptor statusAbenaa M Brewster
Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, Texas 77230 1439, USA
Cancer 118:5637-43. 2012..The objective of this study was to evaluate the benefits of CPM using a propensity scoring approach that reduces selection bias from the nonrandom assignment of patients in observational studies...
Tumor-suppressor activity of RRIG1 in breast cancerGuihong Zhang
Department of Clinical Cancer Prevention, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
BMC Cancer 11:32. 2011..The aim of this study was to determine whether RRIG1 plays a role in breast cancer, such as in the suppression of breast cancer cell growth and invasion...
Current knowledge on contralateral prophylactic mastectomy among women with sporadic breast cancerAbenaa M Brewster
Department of Clinical Cancer Prevention, University of Texas MD Anderson Cancer Center, Houston, Texas 77230 1439, USA
Oncologist 16:935-41. 2011..Gaps in knowledge about the clinical value of CPM, including patient- and physician-related psychosocial factors that influence the decision-making process of CPM among women with sporadic breast cancer, are highlighted...
Residual risk of breast cancer recurrence 5 years after adjuvant therapyAbenaa M Brewster
Departments of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
J Natl Cancer Inst 100:1179-83. 2008..Breast cancer patients have a substantial residual risk of recurrence, and selected tumor characteristics are associated with late recurrences...
Copy number imbalances between screen- and symptom-detected breast cancers and impact on disease-free survivalA M Brewster
Department of Clinical Cancer Prevention, University of Texas MD Anderson Cancer Center, Houston, 77230, USA
Cancer Prev Res (Phila) 4:1609-16. 2011..Measurement of tumor genotype has the potential to improve discrimination between indolent and aggressive screen-detected tumors and aids patient and physician decision making about use of surgical and adjuvant treatments...
Relationship between epidemiologic risk factors and breast cancer recurrenceAbenaa M Brewster
Department of Clinical Cancer Prevention, The University of Texas M D Anderson Cancer Center, Houston, TX, USA
J Clin Oncol 25:4438-44. 2007..We evaluated the effect of epidemiologic breast cancer risk factors on recurrence in women with early-stage disease...
The impact of obesity on receipt of adjuvant chemotherapy for breast cancer in the National Comprehensive Cancer Network (NCCN) centersA M Brewster
The University of Texas MD Anderson Cancer Center, PO Box 301439, Houston, TX 77230 1439, USA
Breast Cancer Res Treat 130:897-904. 2011..Further investigation is needed into other factors that contribute to patient disparities in the receipt of chemotherapy in major academic centers...
Polymorphisms of the DNA repair genes XPD (Lys751Gln) and XRCC1 (Arg399Gln and Arg194Trp): relationship to breast cancer risk and familial predisposition to breast cancerA M Brewster
Department of Clinical Cancer Prevention, University of Texas M D Anderson Cancer Center, Houston, TX 77230 1439, USA
Breast Cancer Res Treat 95:73-80. 2006..Without imputation methods for handling missing data, a statistically significant association was observed between the genotypes and breast cancer, illustrating the potential for bias in studies that inadequately handle missing data...
Breast carcinoma chemoprevention in the community setting. Estimating risks and benefitsAbenaa M Brewster
Department of Clinical Cancer Prevention, The University of Texas M D Anderson Cancer Center, Houston, Texas 77230 1439, USA
Cancer 103:1147-53. 2005..Baseline incidence also was examined for adverse health events in this community-based cohort compared with participants in the Breast Cancer Prevention Trial...
Conference Report: Eighth Annual AACR International Conference on Frontiers in Cancer Prevention ResearchAbenaa M Brewster
The University of Texas M D Anderson Cancer Center, Houston, 77030, USA
Cancer Prev Res (Phila) 3:1044-8. 2010....
Ductal carcinoma in situ: state of the science and roadmap to advance the fieldHenry M Kuerer
The University of Texas M D Anderson Cancer Center, DCIS Discovery Program and Department of Surgical Oncology, 1515 Holcombe Blvd, Unit 444, Houston, TX 77030, USA
J Clin Oncol 27:279-88. 2009..Understanding of the biology and clinical behavior of DCIS is imperfect. This article highlights the current knowledge base and the scientific roadmap needed to advance the field...
XPD polymorphism and risk of subsequent cancer in individuals with nonmelanoma skin cancerAbenaa M Brewster
Department of Clinical Cancer Prevention, University of Texas M D Anderson Cancer Center, Houston, Texas, USA
Cancer Epidemiol Biomarkers Prev 13:1271-5. 2004..To test this hypothesis, a cohort study was conducted to examine the association between XPD Lys751Gln polymorphism and risk of a second primary cancer in individuals with NMSC...
Relationship between obesity and pathologic response to neoadjuvant chemotherapy among women with operable breast cancerJennifer K Litton
Department of Breast Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX, USA
J Clin Oncol 26:4072-7. 2008..To understand the mechanism through which obesity in breast cancer patients is associated with poorer outcome, we evaluated body mass index (BMI) and response to neoadjuvant chemotherapy (NC) in women with operable breast cancer...
The functional promoter polymorphism (-842G>C) in the PIN1 gene is associated with decreased risk of breast cancer in non-Hispanic white women 55 years and youngerChan H Han
Department of Epidemiology, Unit 1365, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
Breast Cancer Res Treat 122:243-9. 2010..In conclusion, the PIN1 polymorphisms may contribute to the etiology of sporadic breast cancer in non-Hispanic white women 55 years and younger. Further validation in large population-based studies is needed...
Randomized trial of adjuvant 13-cis-retinoic acid and interferon alfa for patients with aggressive skin squamous cell carcinomaAbenaa M Brewster
Department of Clinical Cancer Prevention, The University of Texas M D Anderson Cancer Center, Houston, TX 77230 1439, USA
J Clin Oncol 25:1974-8. 2007....
Genetic variants in the H2AFX promoter region are associated with risk of sporadic breast cancer in non-Hispanic white women aged <or=55 yearsJiachun Lu
Department of Epidemiology, Unit 1365, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX, 77030, USA
Breast Cancer Res Treat 110:357-66. 2008..Larger association studies and related functional studies are warranted to confirm these findings...
Phase I/II study of G3139 (Bcl-2 antisense oligonucleotide) in combination with doxorubicin and docetaxel in breast cancerStacy L Moulder
Department of Breast Medical Oncology, Pathology, Surgical Oncology, Radiation Oncology and Experimental Therapeutics, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
Clin Cancer Res 14:7909-16. 2008..We evaluated the efficacy and safety of a Bcl-2 antisense oligonucleotide, G3139, in combination with doxorubicin (A) and docetaxel (T) in patients with locally advanced breast cancer (LABC)...
Research Grants
- Insulin Resistance and Breast Cancer OutcomeAbenaa Brewster; Fiscal Year: 2007..This information will be useful in identifying women who may benefit from interventions to decrease insulin resistance as part of their breast cancer care. ..
