R A Brekken

Summary

Affiliation: The Hope Heart Institute
Country: USA

Publications

  1. ncbi Vascular endothelial growth factor and vascular targeting of solid tumors
    R A Brekken
    The Hope Heart Institute, Department of Vascular Biology, Seattle, WA 98104 2046, USA
    Anticancer Res 21:4221-9. 2001
  2. ncbi VEGF-VEGF receptor complexes as markers of tumor vascular endothelium
    R A Brekken
    The Hope Heart Institute, Department of Vascular Biology, 1124 Columbia St, Seattle, WA 98104-2046, USA
    J Control Release 74:173-81. 2001
  3. ncbi Increased fibrovascular invasion of subcutaneous polyvinyl alcohol sponges in SPARC-null mice
    A D Bradshaw
    Department of Vascular Biology, The Hope Heart Institute, University of Washington, Seattle, Washington 98104, USA
    Wound Repair Regen 9:522-30. 2001
  4. ncbi SPARC, a matricellular protein: at the crossroads of cell-matrix communication
    R A Brekken
    The Department of Vascular Biology, The Hope Heart Institute, 1124 Columbia St, Seattle, WA 98104, USA
    Matrix Biol 19:816-27. 2001

Collaborators

Detail Information

Publications4

  1. ncbi Vascular endothelial growth factor and vascular targeting of solid tumors
    R A Brekken
    The Hope Heart Institute, Department of Vascular Biology, Seattle, WA 98104 2046, USA
    Anticancer Res 21:4221-9. 2001
    ..We conclude that 2C3 might have dual activity as an anti-angiogenic agent by inhibiting VEGFR2 activity and as a vascular targeting agent for selective drug delivery to tumor vessels...
  2. ncbi VEGF-VEGF receptor complexes as markers of tumor vascular endothelium
    R A Brekken
    The Hope Heart Institute, Department of Vascular Biology, 1124 Columbia St, Seattle, WA 98104-2046, USA
    J Control Release 74:173-81. 2001
    ..2C3 may be utilized as both an anti-angiogenic agent by inhibiting VEGFR2 activity and potentially as a vascular targeting agent by binding to blood vessels that express the VEGF-VEGFR1 complex...
  3. ncbi Increased fibrovascular invasion of subcutaneous polyvinyl alcohol sponges in SPARC-null mice
    A D Bradshaw
    Department of Vascular Biology, The Hope Heart Institute, University of Washington, Seattle, Washington 98104, USA
    Wound Repair Regen 9:522-30. 2001
    ....
  4. ncbi SPARC, a matricellular protein: at the crossroads of cell-matrix communication
    R A Brekken
    The Department of Vascular Biology, The Hope Heart Institute, 1124 Columbia St, Seattle, WA 98104, USA
    Matrix Biol 19:816-27. 2001
    ..SPARC is a prototypical matricellular protein that functions to regulate cell-matrix interactions and thereby influences many important physiological and pathological processes...