Research Topics
| Molly BogueSummaryAffiliation: The Jackson Laboratory Country: USA Publications
Research Grants
| Collaborators
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Detail Information
Publications
Mouse Phenome Database (MPD)Molly A Bogue
The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA
Nucleic Acids Res 35:D643-9. 2007..The laboratory mouse is a premier genetic model for understanding human biology and pathology; MPD facilitates research that uses the mouse to identify and determine the function of genes participating in normal and disease pathways...
The Collaborative Cross, a community resource for the genetic analysis of complex traitsGary A Churchill
The Jackson Laboratory, 600 Main Street Bar Harbor, Maine 04609, USA
Nat Genet 36:1133-7. 2004..The Collaborative Cross will provide a common reference panel specifically designed for the integrative analysis of complex systems and will change the way we approach human health and disease...
Large-scale, high-throughput screening for coagulation and hematologic phenotypes in miceLuanne L Peters
The Jackson Laboratory, Bar Harbor, Maine 04609, USA
Physiol Genomics 11:185-93. 2002..These data, freely available on the World Wide Web, allow investigators to knowledgeably select the most appropriate strain(s) to meet their individual study designs and goals...
Mouse phenome databaseStephen C Grubb
The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA
Nucleic Acids Res 37:D720-30. 2009..jax.org/phenome/trytools)...
The Mouse Phenome ProjectMolly A Bogue
The Jackson Laboratory, 600 Main Street, Bar Harbor, Maine 04609, USA
Genetica 122:71-4. 2004....
A collaborative database of inbred mouse strain characteristicsStephen C Grubb
The Jackson Laboratory, Bar Harbor, ME 04609, USA
Bioinformatics 20:2857-9. 2004..The MPD as of February 2004 contains approximately 500 phenotypic parameters relevant to human health, voluntarily contributed by several dozen investigators and laboratories. AVAILABILITY: www.jax.org/phenome..
Invited review: Identifying new mouse models of cardiovascular disease: a review of high-throughput screens of mutagenized and inbred strainsKaren L Svenson
The Jackson Laboratory, Bar Harbor, Maine 04609, USA
J Appl Physiol 94:1650-9; discussion 1673. 2003..Here, we review our cardiovascular screens and present some hypertensive, obese, and cardiovascular models identified with this approach...
Aging in inbred strains of mice: study design and interim report on median lifespans and circulating IGF1 levelsRong Yuan
The Jackson Aging Center at The Jackson Laboratory, Bar Harbor, ME 04609, USA
Aging Cell 8:277-87. 2009..53, P < 0.01). These results support the hypothesis that the IGF1 pathway plays a key role in regulating longevity in mice and indicates that common genetic mechanisms may exist for regulating IGF1 levels and lifespan...
Use of a dense single nucleotide polymorphism map for in silico mapping in the mouseMathew T Pletcher
Genomics Institute of the Novartis Research Foundation, San Diego, California, USA
PLoS Biol 2:e393. 2004..The inferred haplotype data also facilitates the refinement of QTL regions such that candidate genes can be more easily identified and characterized as shown for adenylate cyclase 7...
A sequence-based variation map of 8.27 million SNPs in inbred mouse strainsKelly A Frazer
Perlegen Sciences, 2021 Stierlin Court, Mountain View, California 94043, USA
Nature 448:1050-3. 2007..The considerable regional redundancy of the SNP data will facilitate imputation of the majority of these genotypes in less-densely typed classical inbred strains to provide a complete view of variation in additional strains...
Identification of candidate alkylator-induced cancer susceptibility genes by whole genome scanning in miceTimothy S Fenske
Department of Internal Medicine, Washington University School of Medicine, St. Louis, Missouri 63110, USA
Cancer Res 66:5029-38. 2006....
Acoustic startle and prepulse inhibition in 40 inbred strains of miceJames F Willott
Department of Psychology, University of South Florida, Tampa 33620, USA
Behav Neurosci 117:716-27. 2003..Previously obtained measures of hearing sensitivity in the same inbred strains were not significantly correlated with ASR or PPI measures...
Research Grants
- Complex Trait Consortium 2004, 3rd Annual ConferenceMolly Bogue; Fiscal Year: 2004..Due to its relatively small size and interactive format, this conference represents a unique and rare opportunity for established investigators and students to interact with speakers and other experts that we expect to attend. ..
- Phenome ProjectMolly Bogue; Fiscal Year: 2009..abstract_text> ..
- Mouse Phenome ProjectMolly A Bogue; Fiscal Year: 2010....
