David M Bisaro

Summary

Affiliation: The Ohio State University
Country: USA

Publications

  1. pmc Functional modulation of the geminivirus AL2 transcription factor and silencing suppressor by self-interaction
    Xiaojuan Yang
    Biotechnology Center, Ohio State University, 1060 Carmack Road, Columbus, OH 43210, USA
    J Virol 81:11972-81. 2007
  2. pmc Development of a gene silencing DNA vector derived from a broad host range geminivirus
    Edward M Golenberg
    Department of Biological Sciences, Wayne State University, Detroit, MI 48202, USA
    Plant Methods 5:9. 2009
  3. ncbi request reprint Silencing suppression by geminivirus proteins
    David M Bisaro
    Department of Molecular Genetics and Plant Biotechnology Center, The Ohio State University, Columbus, OH 43210, USA
    Virology 344:158-68. 2006
  4. pmc Geminivirus AL2 and L2 proteins suppress transcriptional gene silencing and cause genome-wide reductions in cytosine methylation
    R Cody Buchmann
    Department of Molecular Genetics, The Ohio State University, Columbus, Ohio 43210, USA
    J Virol 83:5005-13. 2009
  5. pmc Adenosine kinase inhibition and suppression of RNA silencing by geminivirus AL2 and L2 proteins
    Hui Wang
    Biotechnology Center, Ohio State University, 201 Rightmire Hall, 1060 Carmack Road, Columbus, OH 43210, USA
    J Virol 79:7410-8. 2005
  6. pmc Arabidopsis double-stranded RNA binding protein DRB3 participates in methylation-mediated defense against geminiviruses
    Priya Raja
    Department of Molecular Genetics, Center for Applied Plant Sciences, and Center for RNA Biology, The Ohio State University, Columbus, Ohio, USA
    J Virol 88:2611-22. 2014
  7. pmc Adenosine kinase is inactivated by geminivirus AL2 and L2 proteins
    Hui Wang
    Department of Molecular Genetics, Plant Biotechnology Center, Ohio State University, Columbus, Ohio 43210, USA
    Plant Cell 15:3020-32. 2003
  8. pmc Characterization of the RNA silencing suppression activity of the Ebola virus VP35 protein in plants and mammalian cells
    Yali Zhu
    Department of Molecular Virology, Immunology and Medical Genetics, The Ohio State University, Columbus, Ohio, USA
    J Virol 86:3038-49. 2012
  9. pmc Viral genome methylation as an epigenetic defense against geminiviruses
    Priya Raja
    Department of Molecular Genetics, Plant Biotechnology Center, and Program in Molecular, Cellular and Developmental Biology, The Ohio State University, Columbus, Ohio 43210, USA
    J Virol 82:8997-9007. 2008
  10. doi request reprint RNA silencing directed against geminiviruses: post-transcriptional and epigenetic components
    Priya Raja
    Department of Molecular Genetics and Plant Biotechnology Center, and the Graduate Program in Molecular, Cellular, and Developmental Biology, The Ohio State University, Columbus, OH 43210, USA
    Biochim Biophys Acta 1799:337-51. 2010

Collaborators

  • John A Lindbo
  • Hui Wang
  • Shaheen Asad
  • Priya Raja
  • R Cody Buchmann
  • Jamie N Jackel
  • Garry Sunter
  • Gireesha Mohannath
  • Yali Zhu
  • Zetang Wu
  • Deborah S Parris
  • Kenneth J Buckley
  • Jamie N Wolf
  • Edward M Golenberg
  • Kyung Il Kim
  • Xiaojuan Yang
  • Linhui Hao
  • Udit Singhal
  • Sizhun Li
  • Isaac M Heard
  • Veena Patil
  • Allie K Adams
  • Youn Hyung Lee
  • Nil Celebi Cherukuri
  • Monica Crary
  • Leandria C Hancock
  • Natalie M Villafranco
  • D Noah Sather
  • Bradley C Sanville
  • In Sik Chung
  • Surendranath Baliji

Detail Information

Publications16

  1. pmc Functional modulation of the geminivirus AL2 transcription factor and silencing suppressor by self-interaction
    Xiaojuan Yang
    Biotechnology Center, Ohio State University, 1060 Carmack Road, Columbus, OH 43210, USA
    J Virol 81:11972-81. 2007
    ..Thus, AL2 self-interaction correlates with nuclear localization and efficient activation of transcription, whereas AL2 and L2 monomers can suppress local silencing by interacting with ADK in the cytoplasm...
  2. pmc Development of a gene silencing DNA vector derived from a broad host range geminivirus
    Edward M Golenberg
    Department of Biological Sciences, Wayne State University, Detroit, MI 48202, USA
    Plant Methods 5:9. 2009
    ..We present a new, unipartite vector that is derived from a curtovirus that has a broad host range and will be amenable to use in many non-model systems...
  3. ncbi request reprint Silencing suppression by geminivirus proteins
    David M Bisaro
    Department of Molecular Genetics and Plant Biotechnology Center, The Ohio State University, Columbus, OH 43210, USA
    Virology 344:158-68. 2006
    ..Recent advances in our understanding of different geminivirus silencing suppressors indicate that they can affect all three pathways, suggesting that multiple aspects of silencing impact geminivirus replication...
  4. pmc Geminivirus AL2 and L2 proteins suppress transcriptional gene silencing and cause genome-wide reductions in cytosine methylation
    R Cody Buchmann
    Department of Molecular Genetics, The Ohio State University, Columbus, Ohio 43210, USA
    J Virol 83:5005-13. 2009
    ..To our knowledge, this is the first report that viral proteins can inhibit TGS...
  5. pmc Adenosine kinase inhibition and suppression of RNA silencing by geminivirus AL2 and L2 proteins
    Hui Wang
    Biotechnology Center, Ohio State University, 201 Rightmire Hall, 1060 Carmack Road, Columbus, OH 43210, USA
    J Virol 79:7410-8. 2005
    ..Further, since AL2(1-100) is as effective a suppressor as the full-length AL2 protein, activation and silencing suppression appear to be independent activities...
  6. pmc Arabidopsis double-stranded RNA binding protein DRB3 participates in methylation-mediated defense against geminiviruses
    Priya Raja
    Department of Molecular Genetics, Center for Applied Plant Sciences, and Center for RNA Biology, The Ohio State University, Columbus, Ohio, USA
    J Virol 88:2611-22. 2014
    ..These studies reveal that in addition to its previously established role in the miRNA pathway, DRB3 also functions in antiviral RdDM...
  7. pmc Adenosine kinase is inactivated by geminivirus AL2 and L2 proteins
    Hui Wang
    Department of Molecular Genetics, Plant Biotechnology Center, Ohio State University, Columbus, Ohio 43210, USA
    Plant Cell 15:3020-32. 2003
    ..AL2 proteins also have been shown to act as suppressors of RNA silencing, an adaptive host defense response. A possible relationship between ADK inactivation and silencing suppression is discussed...
  8. pmc Characterization of the RNA silencing suppression activity of the Ebola virus VP35 protein in plants and mammalian cells
    Yali Zhu
    Department of Molecular Virology, Immunology and Medical Genetics, The Ohio State University, Columbus, Ohio, USA
    J Virol 86:3038-49. 2012
    ..The results suggest the importance of VP35-protein interactions in blocking silencing in a system (mammalian) that cannot amplify dsRNA...
  9. pmc Viral genome methylation as an epigenetic defense against geminiviruses
    Priya Raja
    Department of Molecular Genetics, Plant Biotechnology Center, and Program in Molecular, Cellular and Developmental Biology, The Ohio State University, Columbus, Ohio 43210, USA
    J Virol 82:8997-9007. 2008
    ..In addition, our results establish that geminiviruses can be useful models for genome methylation in plants and suggest that there are redundant pathways leading to cytosine methylation...
  10. doi request reprint RNA silencing directed against geminiviruses: post-transcriptional and epigenetic components
    Priya Raja
    Department of Molecular Genetics and Plant Biotechnology Center, and the Graduate Program in Molecular, Cellular, and Developmental Biology, The Ohio State University, Columbus, OH 43210, USA
    Biochim Biophys Acta 1799:337-51. 2010
    ..Here we use the DNA-containing geminiviruses as models to discuss what is currently known about both types of antiviral silencing, and viral suppression of PTGS and TGS as a counterdefense...
  11. pmc A complex containing SNF1-related kinase (SnRK1) and adenosine kinase in Arabidopsis
    Gireesha Mohannath
    Department of Molecular Genetics, Center for Applied Plant Sciences, and Center for RNA Biology, The Ohio State University, Columbus, Ohio, United States of America
    PLoS ONE 9:e87592. 2014
    ..This study establishes the existence of SnRK1-ADK complexes that may play important roles in energy homeostasis and cellular responses to biotic and abiotic stress. ..
  12. pmc Geminivirus AL2 and L2 proteins interact with and inactivate SNF1 kinase
    Linhui Hao
    Department of Molecular Genetics, Plant Biotechnology Center, The Ohio State University, Columbus, Ohio 43210, USA
    Plant Cell 15:1034-48. 2003
    ..They also indicate that geminiviruses are able to modify host metabolism to their own advantage, and they provide a molecular link between metabolic status and inherent susceptibility to viral pathogens...
  13. pmc Analysis of geminivirus AL2 and L2 proteins reveals a novel AL2 silencing suppressor activity
    Jamie N Jackel
    Department of Molecular Genetics, Center for Applied Plant Sciences, Center for RNA Biology, and Graduate Program in Molecular, Cellular, and Developmental Biology, The Ohio State University, Columbus, Ohio, USA
    J Virol 89:3176-87. 2015
    ....
  14. pmc Herpes simplex virus type 1 suppresses RNA-induced gene silencing in mammalian cells
    Zetang Wu
    Graduate Program in Molecular, Cellular, and Developmental Biology, Ohio State University, Columbus, Ohio 43210, USA
    J Virol 83:6652-63. 2009
    ....
  15. ncbi request reprint Identification of a minimal sequence required for activation of the tomato golden mosaic virus coat protein promoter in protoplasts
    Garry Sunter
    Department of Molecular Genetics and Plant Biotechnology Center, The Ohio State University, Columbus 43210, USA
    Virology 305:452-62. 2003
    ..Thus, in a protoplast system which models mesophyll, regulation of the minimal CP promoter involves both activation and derepression by TrAP...
  16. ncbi request reprint Improved expression of recombinant GFP using a replicating vector based on Beet curly top virus in leaf-disks and infiltrated Nicotiana benthamiana leaves
    Kyung Il Kim
    Graduate School of Biotechnology and Plant Metabolism Research Center, Kyung Hee University, Suwon 449 701, Korea
    Plant Mol Biol 64:103-12. 2007
    ..Expression of recombinant GFP from Agrobacterium-inoculated leaf-disks of N. benthamiana was further enhanced up to 240% in the presence of post-transcriptional gene silencing suppressor p19...