J A Bibb

Summary

Affiliation: The Rockefeller University
Country: USA

Publications

  1. pmc Severe deficiencies in dopamine signaling in presymptomatic Huntington's disease mice
    J A Bibb
    Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, NY 10021 6399, USA
    Proc Natl Acad Sci U S A 97:6809-14. 2000
  2. ncbi Effects of chronic exposure to cocaine are regulated by the neuronal protein Cdk5
    J A Bibb
    Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, 1230 York Avenue, New York, New York 10021, USA
    Nature 410:376-80. 2001
  3. ncbi Phosphorylation of protein phosphatase inhibitor-1 by Cdk5
    J A Bibb
    Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, New York 10021 6399, USA
    J Biol Chem 276:14490-7. 2001
  4. pmc Regulation of cyclin-dependent kinase 5 and casein kinase 1 by metabotropic glutamate receptors
    F Liu
    Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, NY 10021, USA
    Proc Natl Acad Sci U S A 98:11062-8. 2001
  5. ncbi Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons
    J A Bibb
    Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, New York 10021, USA
    Nature 402:669-71. 1999
  6. ncbi Drugs of abuse modulate the phosphorylation of ARPP-21, a cyclic AMP-regulated phosphoprotein enriched in the basal ganglia
    G L Caporaso
    Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA
    Neuropharmacology 39:1637-44. 2000

Detail Information

Publications6

  1. pmc Severe deficiencies in dopamine signaling in presymptomatic Huntington's disease mice
    J A Bibb
    Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, NY 10021 6399, USA
    Proc Natl Acad Sci U S A 97:6809-14. 2000
    ..HD mice also show defects in dopamine-regulated ion channels and in the D(1) dopamine/DARPP-32 signaling cascade. These presymptomatic defects may contribute to HD pathology...
  2. ncbi Effects of chronic exposure to cocaine are regulated by the neuronal protein Cdk5
    J A Bibb
    Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, 1230 York Avenue, New York, New York 10021, USA
    Nature 410:376-80. 2001
    ..Our results suggest that changes in Cdk5 levels mediated by DeltaFosB, and resulting alterations in signalling involving D1 dopamine receptors, contribute to adaptive changes in the brain related to cocaine addiction...
  3. ncbi Phosphorylation of protein phosphatase inhibitor-1 by Cdk5
    J A Bibb
    Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, New York 10021 6399, USA
    J Biol Chem 276:14490-7. 2001
    ....
  4. pmc Regulation of cyclin-dependent kinase 5 and casein kinase 1 by metabotropic glutamate receptors
    F Liu
    Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, NY 10021, USA
    Proc Natl Acad Sci U S A 98:11062-8. 2001
    ..Together these results indicate that a CK1-Cdk5-DARPP-32 cascade may be involved in the regulation by mGluR agonists of Ca(2+) channels...
  5. ncbi Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons
    J A Bibb
    Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, New York 10021, USA
    Nature 402:669-71. 1999
    ..Thus DARPP-32 is a bifunctional signal transduction molecule which, by distinct mechanisms, controls a serine/threonine kinase and a serine/threonine phosphatase...
  6. ncbi Drugs of abuse modulate the phosphorylation of ARPP-21, a cyclic AMP-regulated phosphoprotein enriched in the basal ganglia
    G L Caporaso
    Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA
    Neuropharmacology 39:1637-44. 2000
    ..We speculate that ARPP-21 might mediate some of the physiologic effects of dopamine and certain drugs of abuse in the basal ganglia...