Gourab Bhattacharjee

Summary

Affiliation: The Scripps Research Institute
Country: USA

Publications

  1. ncbi Regulation of tissue factor--mediated initiation of the coagulation cascade by cell surface grp78
    Gourab Bhattacharjee
    Department of Immunology, The Scripps Research Institute, SP258, La Jolla, CA 92037, USA
    Arterioscler Thromb Vasc Biol 25:1737-43. 2005
  2. ncbi Factor Xa binding to annexin 2 mediates signal transduction via protease-activated receptor 1
    Gourab Bhattacharjee
    Scripps Research Institute, SP 258, 10550 N Torrey Pines Rd, La Jolla, CA 92037, USA
    Circ Res 102:457-64. 2008
  3. ncbi A selective tumor microvasculature thrombogen that targets a novel receptor complex in the tumor angiogenic microenvironment
    Amr El-Sheikh
    Department of Immunology, The Scripps Research Institute, La Jolla, California 92037, USA
    Cancer Res 65:11109-17. 2005
  4. ncbi Dendritic cell PAR1-S1P3 signalling couples coagulation and inflammation
    Frank Niessen
    Department of Immunology, The Scripps Research Institute, La Jolla, California 92037, USA
    Nature 452:654-8. 2008
  5. ncbi In vivo interrogation of the molecular display of atherosclerotic lesion surfaces
    Cheng Liu
    Department of Immunology and Vascular Biology, Mail Code 204, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037 1092, USA
    Am J Pathol 163:1859-71. 2003
  6. ncbi Dexamethasone enhances LPS induction of tissue factor expression in human monocytic cells by increasing tissue factor mRNA stability
    K Veera Reddy
    Department of Immunology, The Scripps Research Institute, 10550 North Torrey Pines Road, CVN-18, La Jolla, CA 92037, USA
    J Leukoc Biol 76:145-51. 2004
  7. ncbi Regulation of macrophage procoagulant responses by the tissue factor cytoplasmic domain in endotoxemia
    Jasimuddin Ahamed
    The Rockefeller University, New York, NY, USA
    Blood 109:5251-9. 2007

Collaborators

Detail Information

Publications7

  1. ncbi Regulation of tissue factor--mediated initiation of the coagulation cascade by cell surface grp78
    Gourab Bhattacharjee
    Department of Immunology, The Scripps Research Institute, SP258, La Jolla, CA 92037, USA
    Arterioscler Thromb Vasc Biol 25:1737-43. 2005
    ..To test the hypothesis that Grp78 negatively regulates cell surface tissue factor (TF) procoagulant activity and whether this is mediated by physical interaction...
  2. ncbi Factor Xa binding to annexin 2 mediates signal transduction via protease-activated receptor 1
    Gourab Bhattacharjee
    Scripps Research Institute, SP 258, 10550 N Torrey Pines Rd, La Jolla, CA 92037, USA
    Circ Res 102:457-64. 2008
    ..We propose that annexin 2 serves to regulate factor Xa signaling specifically in the absence of cell surface TF and may thus play physiological or pathological roles when factor Xa is generated in a TF-depleted environment...
  3. ncbi A selective tumor microvasculature thrombogen that targets a novel receptor complex in the tumor angiogenic microenvironment
    Amr El-Sheikh
    Department of Immunology, The Scripps Research Institute, La Jolla, California 92037, USA
    Cancer Res 65:11109-17. 2005
    ..In vitro, we show that the HBDt structure has its highest affinity for chondroitin 6 sulfate. We show the potential of this HBDt.TFt as a candidate therapeutic and elucidate its target in vivo...
  4. ncbi Dendritic cell PAR1-S1P3 signalling couples coagulation and inflammation
    Frank Niessen
    Department of Immunology, The Scripps Research Institute, La Jolla, California 92037, USA
    Nature 452:654-8. 2008
    ..Thus, activation of dendritic cells by coagulation in the lymphatics emerges as a previously unknown mechanism that promotes systemic inflammation and lethality in decompensated innate immune responses...
  5. ncbi In vivo interrogation of the molecular display of atherosclerotic lesion surfaces
    Cheng Liu
    Department of Immunology and Vascular Biology, Mail Code 204, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037 1092, USA
    Am J Pathol 163:1859-71. 2003
    ..These peptides provide a set of probes to interrogate the cell surface repertoire associated with atherogenesis and thrombotic complications...
  6. ncbi Dexamethasone enhances LPS induction of tissue factor expression in human monocytic cells by increasing tissue factor mRNA stability
    K Veera Reddy
    Department of Immunology, The Scripps Research Institute, 10550 North Torrey Pines Road, CVN-18, La Jolla, CA 92037, USA
    J Leukoc Biol 76:145-51. 2004
    ..Therefore, despite an inhibition of TF gene transcription, Dex enhances TF expression in human monocytic cells by increasing the stability of TF mRNA...
  7. ncbi Regulation of macrophage procoagulant responses by the tissue factor cytoplasmic domain in endotoxemia
    Jasimuddin Ahamed
    The Rockefeller University, New York, NY, USA
    Blood 109:5251-9. 2007
    ..The present study demonstrates a new role of the TF cytoplasmic domain in an autoregulatory pathway that controls LPS-induced TF expression in macrophages and procoagulant responses in endotoxemia...