Genomes and Genes
D Q Beversdorf
Affiliation: The Ohio State University
- Increased discrimination of "false memories" in autism spectrum disorderD Q Beversdorf
Department of Neurology, Ohio State University Medical Center, 1654 Upham Drive, Columbus, OH 43210, USA
Proc Natl Acad Sci U S A 97:8734-7. 2000..Research directed at defining the range of tasks performed superiorly by high-functioning individuals with ASD will be important for optimal vocational rehabilitation...
- Timing of prenatal stressors and autismD Q Beversdorf
Department of Neurology, Ohio State University Medical Center, Columbus, OH 43210, USA
J Autism Dev Disord 35:471-8. 2005..Future prospective studies would be needed to confirm this finding...
- The effect of semantic and emotional context on written recall for verbal language in high functioning adults with autism spectrum disorderD Q Beversdorf
Ohio State University Medical Centre, Department of Neurology, Columbus 43210, USA
J Neurol Neurosurg Psychiatry 65:685-92. 1998....
- Brief report: macrographia in high-functioning adults with autism spectrum disorderD Q Beversdorf
Department of Neurology, Ohio State University Medical Center, 1654 Upham Drive, Columbus, Ohio 43210, USA
J Autism Dev Disord 31:97-101. 2001..This finding may correlate with the anatomical abnormalities present in the cerebellum of individuals with autism spectrum disorder...
- Depressive symptoms, omega-6:omega-3 fatty acids, and inflammation in older adultsJanice K Kiecolt-Glaser
Department of Psychiatry, Ohio State University College of Medicine, 1670 Upham Drive, Columbus, OH 43210, USA
Psychosom Med 69:217-24. 2007..Dietary intakes of omega-3 (n-3) and omega-6 (n-6) PUFAs also influence inflammation; high n-6:n-3 ratios enhance proinflammatory cytokine production, although n-3 has anti-inflammatory properties...
- The effect of auditory stressors on cognitive flexibilityAshleigh Hillier
The Ohio State University Medical Center, Columbus, OH 43210, USA
Neurocase 12:228-31. 2006..These findings suggest that stress caused by an auditory stressor may negatively impact performance on more complex tasks requiring a rapid search of the semantic and lexical associative networks...
- High-resolution 8 Tesla imaging of the formalin-fixed normal human hippocampusDonald W Chakeres
Department of Radiology, University Hospital, Ohio State University, Columbus, Ohio 43210 1228, USA
Clin Anat 18:88-91. 2005..High field, high-resolution MRI can be used to depict multiple layers of the formalin-fixed human hippocampus in vitro using an 8 T whole-body scanner, a TEM coil, and short acquisition times compatible with human imaging in vivo...
- Financial and psychological risk attitudes associated with two single nucleotide polymorphisms in the nicotine receptor (CHRNA4) geneBrian E Roe
Department of Agricultural, Environmental and Development Economics, Ohio State University, Columbus, Ohio, USA
PLoS ONE 4:e6704. 2009....
- A pilot open-label trial of citalopram for restless activity and aberrant motor behaviors in Alzheimer diseaseDouglas W Scharre
Division of Cognitive Neurology, Department of Neurology, The Ohio State University, Columbus, OH 43210, USA
Am J Geriatr Psychiatry 11:687-91. 2003..In a prospective, open-label pilot study in probable-Alzheimer disease (AD) outpatients, the authors investigated the efficacy of citalopram to reduce restless activity and aberrant motor behaviors...
- Self-administered Gerocognitive Examination (SAGE): a brief cognitive assessment Instrument for mild cognitive impairment (MCI) and early dementiaDouglas W Scharre
Department of Neurology, Ohio State University, Columbus, OH, USA
Alzheimer Dis Assoc Disord 24:64-71. 2010....
- Problem solving ability in patients with mild cognitive impairmentDavid Q Beversdorf
Department of Neurology, The Ohio State University, Columbus, OH, USA
Cogn Behav Neurol 20:44-7. 2007..Our goal is to determine how well a visuospatial problem solving task assessing the cumulative burden of frontal and posterior damage differentiates MCI patients from matched controls...
- Apparent transient effects of recent "ecstasy" use on cognitive performance and extrapyramidal signs in human subjectsRyan M Smith
Department of Neurology, The Ohio State University, 1654 Upham Drive, Rm 461, Columbus, OH 43210, USA
Cogn Behav Neurol 19:157-64. 2006..Our purpose is to investigate cognitive performance and extrapyramidal function early after ecstasy use...
- Blipped multi gradient-echo slice excitation profile imaging (bmGESEPI) for fast T2 * measurements with macroscopic B0 inhomogeneity compensationTrong-Kha Truong
Department of Radiology, The Ohio State University, Columbus, 43210, USA
Magn Reson Med 55:1390-5. 2006..To demonstrate its advantages, T(2) (*) maps were acquired using a conventional multiecho GE method, the mGESEPI method, and the bmGESEPI method in postmortem and in vivo human brains at 8 T...
- Effects of naturalistic stressors on cognitive flexibility and working memory task performanceKatherine H Renner
Department of Biology, The Ohio State University, Columbus, OH, USA
Neurocase 16:293-300. 2010..Further work will be necessary to better understand the pharmacological mechanism of the effects of these types of stressors, and the clinical implications of this effect...
- Conduction aphasia and the arcuate fasciculus: A reexamination of the Wernicke-Geschwind modelJ M Anderson
Department of Neurology, University of Florida, Gainesville, USA
Brain Lang 70:1-12. 1999..These findings suggest that cortical dysfunction alone may induce conduction aphasia...
- Increased task difficulty results in greater impact of noradrenergic modulation of cognitive flexibilityHeather L Campbell
The Ohio State University College of Nursing, Columbus, OH 43210, USA
Pharmacol Biochem Behav 88:222-9. 2008....
- Lack of dopaminergic modulation of cognitive flexibilityShawn F Smyth
Department of Neurology, The Ohio State University, Columbus, OH 43210, USA
Cogn Behav Neurol 20:225-9. 2007..To evaluate performance on a cognitive flexibility task after administration of a dopaminergic agonist...
- The effect of propranolol on cognitive flexibility and memory in acute cocaine withdrawalBrendan J Kelley
Department of Neurology, Mayo Clinic, Rochester, MN, USA
Neurocase 13:320-7. 2007..Cocaine withdrawal treatment is characterized by high failure rates. Further research is needed to determine the role this finding of a reversible cognitive impairment in cocaine withdrawal has in treatment...
- Beta-adrenergic modulation of cognitive flexibility during stressJessica K Alexander
The Ohio State University, Columbus, OH 43210, USA
J Cogn Neurosci 19:468-78. 2007..This may provide support for the hypothesis that stress-related impairments in cognitive flexibility are related to the noradrenergic system...
- Network model of decreased context utilization in autism spectrum disorderDavid Q Beversdorf
Department of Neurology, The Ohio State University Medical Center, Means Hall 469, 1654 Upham Drive, Columbus, OH 43210, USA
J Autism Dev Disord 37:1040-8. 2007..This may have an anatomic basis in diminished hippocampal neuronal arborization and the abnormal minicolumnar pathology in ASD...
- Effect of anxiolytics on cognitive flexibility in problem solvingJennifer A Silver
Ohio State University, Columbus, Ohio, USA
Cogn Behav Neurol 17:93-7. 2004..CONCLUSIONS: Therefore, this suggests that the phenomenon of noradrenergic modulation of cognitive flexibility does not result from a nonspecific anxiolytic effect, but rather is specific to the noradrenergic system...
- Effect of propranolol on functional connectivity in autism spectrum disorder--a pilot studyAnanth Narayanan
Integrated Biomedical Sciences Graduate Program, The Ohio State University, Columbus, OH, USA
Brain Imaging Behav 4:189-97. 2010..Comparison of functional connectivity between pre-defined ROI-pairs revealed a significant increase with propranolol compared to nadolol, suggesting a potential imaging marker for the cognitive effects of propranolol in ASD...
- Effects of static and radiofrequency magnetic field inhomogeneity in ultra-high field magnetic resonance imagingTrong-Kha Truong
Department of Radiology, The Ohio State University, Columbus, OH 43210, USA
Magn Reson Imaging 24:103-12. 2006..Mapping of the B(0) and B(1) inhomogeneity is important in characterizing image artifacts. This will help develop better B(0) and B(1) inhomogeneity correction methods...
- Effects of semantic relatedness on recall of stimuli preceding emotional oddballsRyan M Smith
Neuroscience Graduate Studies Program, The Ohio State University, Columbus, Ohio, USA
J Int Neuropsychol Soc 14:620-8. 2008..Our findings demonstrate the ability of emotion and semantic memory to interact to mutually enhance free-recall...
- Apolipoprotein E (APOE) genotype has dissociable effects on memory and attentional-executive network function in Alzheimer's diseaseDavid A Wolk
Department of Neurology, University of Pennsylvania, Philadelphia, PA 19104, USA
Proc Natl Acad Sci U S A 107:10256-61. 2010....
- Effect of propranolol on naming in chronic Broca's aphasia with anomiaDavid Q Beversdorf
Department of Neurology, The Ohio State University Medical Center, Columbus, OH 43210, USA
Neurocase 13:256-9. 2007..Naming was better after propranolol than after placebo, suggesting a potential benefit from propranolol in chronic Broca's aphasia with anomia. Larger follow-up studies are necessary to further investigate this effect...
- Cognitive impairment in acute cocaine withdrawalBrendan J Kelley
Department of Neurology, The Ohio State University, Columbus, Ohio 43210, USA
Cogn Behav Neurol 18:108-12. 2005..Further research will explore whether impaired cognitive flexibility related to altered noradrenergic tone could serve as a mechanism for this treatment response...
- Decreased false memory for visually presented shapes and symbols among adults on the autism spectrumAshleigh Hillier
The Ohio State University Medical Center, Columbus, OH, USA
J Clin Exp Neuropsychol 29:610-6. 2007..Findings from the visual paradigm provide further evidence of restricted associative networks in ASD, particularly in the spatial domain...
- Combination therapy of donepezil and vitamin E in Alzheimer diseaseEmily T Klatte
Department of Neurology, Ohio State University, Columbus, Ohio, USA
Alzheimer Dis Assoc Disord 17:113-6. 2003..The long-term combination therapy of donepezil and vitamin E appears beneficial for patients with Alzheimer disease. Future prospective studies would be needed to compare combination treatment to vitamin E and donepezil alone...
- Lack of noradrenergic modulation of indirect semantic primingJacquelyne S Cios
Department of Neurology, The Ohio State University, Columbus, OH, USA
Behav Neurol 21:137-43. 2009....
- Effect of the cold pressor test on memory and cognitive flexibilityKelly Ishizuka
Department of Neurosurgery, University of Minnesota, MN, USA
Neurocase 13:154-7. 2007..The lack of a cold pressor effect on cognitive flexibility may result from an isolated effect on the peripheral noradrenergic system, whereas indirect effects due to nociception on memory may occur...
- Accelerated telomere erosion is associated with a declining immune function of caregivers of Alzheimer's disease patientsAmanda K Damjanovic
Laboratory of Immunology, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA
J Immunol 179:4249-54. 2007..These findings demonstrate that chronic stress is associated with altered T cell function and accelerated immune cell aging as suggested by excessive telomere loss...
- Donepezil in the treatment of dementia with lewy bodiesDavid Q Beversdorf
Am J Geriatr Psychiatry 12:542-4. 2004
- Effect of propranolol on verbal problem solving in autism spectrum disorderDavid Q Beversdorf
Department of Radiology, Thompson Center, University of Missouri, Columbia, MO 65211, USA
Neurocase 14:378-83. 2008..Further study will be necessary to confirm this finding in a larger sample and to compare clinical response with cognitive response to propranolol...
- Central beta-adrenergic modulation of cognitive flexibilityDavid Q Beversdorf
Department of Psychiatry, University of Colorado Health Science Center, Denver, CO 80262, USA
Neuroreport 13:2505-7. 2002..Anagram solution latency scores after propranolol were significantly lower than after nadolol. This suggests a centrally mediated modulatory influence of the noradrenergic system on cognitive flexibility...
- The effect of alpha-2 adrenergic agonists on memory and cognitive flexibilityYoungjee Choi
Washington University, St Louis, MO, USA
Cogn Behav Neurol 19:204-7. 2006..This may have implications for why clonidine has not demonstrated efficacy for cognitive disorders such as Alzheimer disease, despite its known benefit for working memory in animal models...
- Cognitive flexibility, withdrawal, and norepinephrineDavid Beversdorf; Fiscal Year: 2003..OSU is well equipped for these goals, including potential fMRI using the most powerful human MRI in the world, strong neuroscience and psychology programs, and an established drug addiction clinic. ..
- Semantic Network Flexibility Modulation/Autism SpectrumDavid Beversdorf; Fiscal Year: 2007..OSU and my outside consultants are well equipped for my current and future research goals, with ongoing autism research, possible potential for future high-field fMRI, and strong neruoscience training. ..