D M Basso

Summary

Affiliation: The Ohio State University
Country: USA

Publications

  1. ncbi request reprint Descending systems contributing to locomotor recovery after mild or moderate spinal cord injury in rats: experimental evidence and a review of literature
    D Michele Basso
    Division of Physical Therapy, School of Allied Medical Professions, The Ohio State University, Columbus 43210, USA
    Restor Neurol Neurosci 20:189-218. 2002
  2. ncbi request reprint Neuroanatomical substrates of functional recovery after experimental spinal cord injury: implications of basic science research for human spinal cord injury
    D M Basso
    Division of Physical Therapy, School of Allied Medical Professions, The Ohio State University, 306 SAMP, 1583 Perry St, Columbus, OH 43210, USA
    Phys Ther 80:808-17. 2000
  3. ncbi request reprint Basso Mouse Scale for locomotion detects differences in recovery after spinal cord injury in five common mouse strains
    D Michele Basso
    Division of Physical Therapy, School of Allied Medical Professions, The Ohio State University, Columbus, Ohio 43210, USA
    J Neurotrauma 23:635-59. 2006
  4. ncbi request reprint A sensitive and reliable locomotor rating scale for open field testing in rats
    D M Basso
    Department of Cell Biology, Neurobiology and Anatomy, Ohio State University, Columbus, USA
    J Neurotrauma 12:1-21. 1995
  5. ncbi request reprint Physical therapy on trial: the rationale, organization, and impact of a mock trial on physical therapy students' attitudes toward and confidence in research
    Deborah Givens Heiss
    Physical Therapy Division, School of Allied Medical Professions, College of Medicine and Public Health, The Ohio State University, Columbus, Ohio 43210 1234, USA
    J Allied Health 32:202-10. 2003
  6. ncbi request reprint The neuropathological and behavioral consequences of intraspinal microglial/macrophage activation
    P G Popovich
    Department of Molecular Virology, Immunology and Medical Genetics, The Ohio State University College of Medicine and Public Health and School of Allied Medical Professions, Columbus 43210, USA
    J Neuropathol Exp Neurol 61:623-33. 2002
  7. ncbi request reprint Behavioral and histological outcomes following graded spinal cord contusion injury in the C57Bl/6 mouse
    M Ma
    Department of Physiology and Cell Biology, Ohio State University, Columbus, OH 43210, USA
    Exp Neurol 169:239-54. 2001
  8. pmc Delayed Nogo receptor therapy improves recovery from spinal cord contusion
    Xingxing Wang
    Program in Cellular Neuroscience, Neurodegeneration and Repair, Yale University School of Medicine, New Haven, CT 06510, USA
    Ann Neurol 60:540-9. 2006
  9. ncbi request reprint Voluntary wheel running improves recovery from a moderate spinal cord injury
    Christie Engesser-Cesar
    Institute for Brain Aging and Dementia, University of California, Irvine, California 92697 4540, USA
    J Neurotrauma 22:157-71. 2005
  10. ncbi request reprint Stepwise motor and all-or-none sensory recovery is associated with nonlinear sparing after incremental spinal cord injury in rats
    Anne D Kloos
    Division of Physical Therapy, School of Allied Medical Professions, The Ohio State University, 516 Atwell Hall, 1583 Perry Street, Columbus, OH 43210, USA
    Exp Neurol 191:251-65. 2005

Collaborators

Detail Information

Publications16

  1. ncbi request reprint Descending systems contributing to locomotor recovery after mild or moderate spinal cord injury in rats: experimental evidence and a review of literature
    D Michele Basso
    Division of Physical Therapy, School of Allied Medical Professions, The Ohio State University, Columbus 43210, USA
    Restor Neurol Neurosci 20:189-218. 2002
    ..Greater axonal sparing is associated with more extensive recovery. Therefore, we identified the source and relative proportion of spared axons associated with extensive or limited locomotor recovery after SCI...
  2. ncbi request reprint Neuroanatomical substrates of functional recovery after experimental spinal cord injury: implications of basic science research for human spinal cord injury
    D M Basso
    Division of Physical Therapy, School of Allied Medical Professions, The Ohio State University, 306 SAMP, 1583 Perry St, Columbus, OH 43210, USA
    Phys Ther 80:808-17. 2000
    ..Body weight supported treadmill step training is discussed as an example of new facilitatory interventions based on basic science research using animal models...
  3. ncbi request reprint Basso Mouse Scale for locomotion detects differences in recovery after spinal cord injury in five common mouse strains
    D Michele Basso
    Division of Physical Therapy, School of Allied Medical Professions, The Ohio State University, Columbus, Ohio 43210, USA
    J Neurotrauma 23:635-59. 2006
    ..05). The differing behavioral response to SCI suggests inherent genetic factors significantly impact locomotor recovery and must be considered in studies with inbred or genetically engineered mouse strains...
  4. ncbi request reprint A sensitive and reliable locomotor rating scale for open field testing in rats
    D M Basso
    Department of Cell Biology, Neurobiology and Anatomy, Ohio State University, Columbus, USA
    J Neurotrauma 12:1-21. 1995
    ..The BBB Locomotor Rating Scale offers investigators a more discriminating measure of behavioral outcome to evaluate treatments after spinal cord injury...
  5. ncbi request reprint Physical therapy on trial: the rationale, organization, and impact of a mock trial on physical therapy students' attitudes toward and confidence in research
    Deborah Givens Heiss
    Physical Therapy Division, School of Allied Medical Professions, College of Medicine and Public Health, The Ohio State University, Columbus, Ohio 43210 1234, USA
    J Allied Health 32:202-10. 2003
    ..If attitudes predict behavior, these future practitioners are more likely to be physical therapists who critically appraise and use evidence to determine practice...
  6. ncbi request reprint The neuropathological and behavioral consequences of intraspinal microglial/macrophage activation
    P G Popovich
    Department of Molecular Virology, Immunology and Medical Genetics, The Ohio State University College of Medicine and Public Health and School of Allied Medical Professions, Columbus 43210, USA
    J Neuropathol Exp Neurol 61:623-33. 2002
    ..Further development of this model will help to clarify the biological potential of microglia and macrophages and the molecular signals that control their function within the spinal cord...
  7. ncbi request reprint Behavioral and histological outcomes following graded spinal cord contusion injury in the C57Bl/6 mouse
    M Ma
    Department of Physiology and Cell Biology, Ohio State University, Columbus, OH 43210, USA
    Exp Neurol 169:239-54. 2001
    ..The data provide a thorough and quantitative analysis of the effects of contusion injury on long-term behavioral and histological outcome measures in this strain and species...
  8. pmc Delayed Nogo receptor therapy improves recovery from spinal cord contusion
    Xingxing Wang
    Program in Cellular Neuroscience, Neurodegeneration and Repair, Yale University School of Medicine, New Haven, CT 06510, USA
    Ann Neurol 60:540-9. 2006
    ..Myelin-associated inhibitors play a role in limiting axonal growth in the adult central nervous system. Blocking these inhibitors may promote neurological recovery from spinal cord contusion...
  9. ncbi request reprint Voluntary wheel running improves recovery from a moderate spinal cord injury
    Christie Engesser-Cesar
    Institute for Brain Aging and Dementia, University of California, Irvine, California 92697 4540, USA
    J Neurotrauma 22:157-71. 2005
    ..05). Finally, fibronectin staining shows no significant difference in lesion size between the two groups. These data represent the first mouse model showing voluntary exercise improves recovery after SCI...
  10. ncbi request reprint Stepwise motor and all-or-none sensory recovery is associated with nonlinear sparing after incremental spinal cord injury in rats
    Anne D Kloos
    Division of Physical Therapy, School of Allied Medical Professions, The Ohio State University, 516 Atwell Hall, 1583 Perry Street, Columbus, OH 43210, USA
    Exp Neurol 191:251-65. 2005
    ..A hierarchical locomotor recovery based on simple segmental versus complex supraspinal motor control is proposed...
  11. ncbi request reprint Behavioral testing after spinal cord injury: congruities, complexities, and controversies
    D Michele Basso
    Division of Physical Therapy, The Ohio State University, Columbus, Ohio 43210, USA
    J Neurotrauma 21:395-404. 2004
    ..Recent work in translating behavioral tests from rats to mice is also provided. The purpose of this article is to provide a framework by which behavioral testing can be standardized within and across spinal cord injury labs...
  12. ncbi request reprint Passive or active immunization with myelin basic protein impairs neurological function and exacerbates neuropathology after spinal cord injury in rats
    T Bucky Jones
    The Neuroscience Graduate Studies Program, Division of Physical Therapy, The Ohio State University College of Medicine and Public Health, Columbus, Ohio 43210, USA
    J Neurosci 24:3752-61. 2004
    ..These data are consistent with the conventional view of myelin-reactive T-cells as pathological effector cells...
  13. ncbi request reprint Pathological CNS autoimmune disease triggered by traumatic spinal cord injury: implications for autoimmune vaccine therapy
    T Bucky Jones
    The Neuroscience Graduate Studies Program, School of Allied Medical Professions, The Ohio State University College of Medicine and Public Health, Columbus, Ohio 43210, USA
    J Neurosci 22:2690-700. 2002
    ..Consequently, the safe implementation of such therapies requires that future studies define the mechanisms that control T-cell function within the injured CNS...
  14. pmc Remote activation of microglia and pro-inflammatory cytokines predict the onset and severity of below-level neuropathic pain after spinal cord injury in rats
    Megan Ryan Detloff
    Center for Brain and Spinal Cord Repair, Neuroscience Graduate Studies Program, The Ohio State University 43210, USA
    Exp Neurol 212:337-47. 2008
    ..Although the mechanisms of remote microglial activation are unknown, this response may be a viable target for limiting or preventing neuropathic pain after SCI in humans...
  15. ncbi request reprint Three exercise paradigms differentially improve sensory recovery after spinal cord contusion in rats
    Karen J Hutchinson
    Division of Physical Therapy, The Ohio State University, 516 Atwell Hall, 1583 Perry Street, Columbus, OH 43210, USA
    Brain 127:1403-14. 2004
    ..These findings suggest that rhythmic, weight-bearing exercise may be an effective intervention to counter SCI-induced allodynia...
  16. pmc Validity of the walking scale for spinal cord injury and other domains of function in a multicenter clinical trial
    John F Ditunno
    Department of Rehabilitation Medicine, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Neurorehabil Neural Repair 21:539-50. 2007
    ..To demonstrate criterion (concurrent and predictive) and construct validity of the Walking Index for Spinal Cord Injury (WISCI) scale and other walking measures in the Spinal Cord Injury Locomotor Trial (SCILT)...

Research Grants6

  1. SPARING AND EXERCISE TRAINING PROMOTE RECOVERY IN SCI
    Michele Basso; Fiscal Year: 2002
    ..abstract_text> ..
  2. SPARING AND EXERCISE TRAINING PROMOTE RECOVERY IN SCI
    Michele Basso; Fiscal Year: 2003
    ..abstract_text> ..
  3. SPARING AND EXERCISE TRAINING PROMOTE RECOVERY IN SCI
    Michele Basso; Fiscal Year: 2004
    ..abstract_text> ..
  4. SPARING AND EXERCISE TRAINING PROMOTE RECOVERY IN SCI
    Michele Basso; Fiscal Year: 2005
    ..abstract_text> ..
  5. SPARING AND EXERCISE TRAINING PROMOTE RECOVERY IN SCI
    Michele Basso; Fiscal Year: 2006
    ..abstract_text> ..
  6. SPARING AND EXERCISE TRAINING PROMOTE RECOVERY IN SCI
    Michele Basso; Fiscal Year: 2006
    ..abstract_text> ..