Sanford H Barsky

Summary

Affiliation: The Ohio State University
Country: USA

Publications

  1. ncbi request reprint Myoepithelial cells: autocrine and paracrine suppressors of breast cancer progression
    Sanford H Barsky
    Department of Pathology, The Ohio State University College of Medicine, Columbus, Ohio 43210, USA
    J Mammary Gland Biol Neoplasia 10:249-60. 2005
  2. ncbi request reprint Mechanisms of disease: breast tumor pathogenesis and the role of the myoepithelial cell
    Sanford H Barsky
    Department of Pathology, The Ohio State University College of Medicine, Columbus, OH 43210, USA
    Nat Clin Pract Oncol 3:138-51. 2006
  3. pmc Breast carcinomatous tumoral emboli can result from encircling lymphovasculogenesis rather than lymphovascular invasion
    Sepi Mahooti
    Department of Pathology, The Ohio State University College of Medicine, Columbus, Ohio 43210, USA
    Oncotarget 1:131-47. 2010
  4. pmc Identification of Piwil2-like (PL2L) proteins that promote tumorigenesis
    Yin Ye
    Department of Pathology, Ohio State University Medical Center, Columbus, Ohio, United States of America
    PLoS ONE 5:e13406. 2010
  5. pmc Singular v dual inhibition of SNF2L and its isoform, SNF2LT, have similar effects on DNA damage but opposite effects on the DNA damage response, cancer cell growth arrest and apoptosis
    Yin Ye
    Department of Pathology, University of Nevada School of Medicine, Reno, NV, USA
    Oncotarget 3:475-89. 2012
  6. doi request reprint Inhibition of expression of the chromatin remodeling gene, SNF2L, selectively leads to DNA damage, growth inhibition, and cancer cell death
    Yin Ye
    Department of Pathology, University of Nevada School of Medicine, Reno, NV 89557 0350, USA
    Mol Cancer Res 7:1984-99. 2009
  7. doi request reprint Early to intermediate steps of tumor embolic formation involve specific proteolytic processing of E-cadherin regulated by Rab7
    Yin Ye
    Department of Pathology, University of Nevada School of Medicine, Reno, NV 89557, USA
    Mol Cancer Res 10:713-26. 2012
  8. pmc ERalpha suppresses slug expression directly by transcriptional repression
    Yin Ye
    Department of Pathology, The Ohio State University College of Medicine, 129 Hamilton Hall, 1645 Neil Avenue, Columbus, OH 43210, USA
    Biochem J 416:179-87. 2008
  9. doi request reprint Synthetic cannabinoid receptor agonists inhibit tumor growth and metastasis of breast cancer
    Zahida Qamri
    Department of Pathology, Ohio State University Medical Center, Columbus, OH 43210, USA
    Mol Cancer Ther 8:3117-29. 2009
  10. ncbi request reprint E-cadherin accumulation within the lymphovascular embolus of inflammatory breast cancer is due to altered trafficking
    Yin Ye
    Department of Pathology, University of Nevada School of Medicine, Reno, NV 89557, USA
    Anticancer Res 30:3903-10. 2010

Collaborators

Detail Information

Publications25

  1. ncbi request reprint Myoepithelial cells: autocrine and paracrine suppressors of breast cancer progression
    Sanford H Barsky
    Department of Pathology, The Ohio State University College of Medicine, Columbus, Ohio 43210, USA
    J Mammary Gland Biol Neoplasia 10:249-60. 2005
    ....
  2. ncbi request reprint Mechanisms of disease: breast tumor pathogenesis and the role of the myoepithelial cell
    Sanford H Barsky
    Department of Pathology, The Ohio State University College of Medicine, Columbus, OH 43210, USA
    Nat Clin Pract Oncol 3:138-51. 2006
    ..Studies of primary and immortalized myoepithelial cell lines indicate that these cells exhibit a natural tumor suppressor function. Functional studies show that these cells have anti-invasive and antiangiogenic phenotypes...
  3. pmc Breast carcinomatous tumoral emboli can result from encircling lymphovasculogenesis rather than lymphovascular invasion
    Sepi Mahooti
    Department of Pathology, The Ohio State University College of Medicine, Columbus, Ohio 43210, USA
    Oncotarget 1:131-47. 2010
    ..Collectively both experimental as well as observational studies suggested the possibility that these breast cancer emboli resulted from encircling lymphovasculogenesis rather than conventional lymphovascular invasion...
  4. pmc Identification of Piwil2-like (PL2L) proteins that promote tumorigenesis
    Yin Ye
    Department of Pathology, Ohio State University Medical Center, Columbus, Ohio, United States of America
    PLoS ONE 5:e13406. 2010
    ..The identification of PL2L proteins provides a novel insight into the mechanisms of cancer development as well as a novel bridge linking cancer diagnostics and anticancer drug development...
  5. pmc Singular v dual inhibition of SNF2L and its isoform, SNF2LT, have similar effects on DNA damage but opposite effects on the DNA damage response, cancer cell growth arrest and apoptosis
    Yin Ye
    Department of Pathology, University of Nevada School of Medicine, Reno, NV, USA
    Oncotarget 3:475-89. 2012
    ..Cancer cell lines which endogenously express low levels of both SNF2L and its isoform mimic the situation of dual knockdown and permit DNA damage which is allowed to propagate unchecked...
  6. doi request reprint Inhibition of expression of the chromatin remodeling gene, SNF2L, selectively leads to DNA damage, growth inhibition, and cancer cell death
    Yin Ye
    Department of Pathology, University of Nevada School of Medicine, Reno, NV 89557 0350, USA
    Mol Cancer Res 7:1984-99. 2009
    ..This raised the hypothesis that cancers are sensitive to SNF2L knockdown because, unlike their normal counterparts, they lack sufficient compensation from other family members...
  7. doi request reprint Early to intermediate steps of tumor embolic formation involve specific proteolytic processing of E-cadherin regulated by Rab7
    Yin Ye
    Department of Pathology, University of Nevada School of Medicine, Reno, NV 89557, USA
    Mol Cancer Res 10:713-26. 2012
    ....
  8. pmc ERalpha suppresses slug expression directly by transcriptional repression
    Yin Ye
    Department of Pathology, The Ohio State University College of Medicine, 129 Hamilton Hall, 1645 Neil Avenue, Columbus, OH 43210, USA
    Biochem J 416:179-87. 2008
    ..The efficacy of the effect of ERalpha on slug repression was dependent on the overall level of ERalpha. These observations confirmed that slug was an E2-responsive gene...
  9. doi request reprint Synthetic cannabinoid receptor agonists inhibit tumor growth and metastasis of breast cancer
    Zahida Qamri
    Department of Pathology, Ohio State University Medical Center, Columbus, OH 43210, USA
    Mol Cancer Ther 8:3117-29. 2009
    ..These results indicate that CB1 and CB2 receptors could be used to develop novel therapeutic strategies against breast cancer growth and metastasis...
  10. ncbi request reprint E-cadherin accumulation within the lymphovascular embolus of inflammatory breast cancer is due to altered trafficking
    Yin Ye
    Department of Pathology, University of Nevada School of Medicine, Reno, NV 89557, USA
    Anticancer Res 30:3903-10. 2010
    ..These findings suggest that it is the altered E-cadherin trafficking that contributes to its oncogenic rather than suppressive role in IBC...
  11. pmc Precancerous stem cells have the potential for both benign and malignant differentiation
    Li Chen
    Department of Pathology, Ohio State University Medical Center, Columbus, Ohio, United States of America
    PLoS ONE 2:e293. 2007
    ..We anticipate pCSCs to be a novel target for the early detection, prevention, and therapy of cancers...
  12. pmc Pten in stromal fibroblasts suppresses mammary epithelial tumours
    ANTHONY J TRIMBOLI
    Department of Molecular Genetics, College of Biological Sciences, The Ohio State University, Columbus, Ohio 43210, USA
    Nature 461:1084-91. 2009
    ..These findings identify the Pten-Ets2 axis as a critical stroma-specific signalling pathway that suppresses mammary epithelial tumours...
  13. pmc Piwil2 is expressed in various stages of breast cancers and has the potential to be used as a novel biomarker
    James J Liu
    Department of Pathology, Ohio State University Medical Center, Columbus, OH 43210, USA
    Int J Clin Exp Pathol 3:328-37. 2010
    ..In conclusion, piwil2 is expressed in various stages of breast cancers and has the potential to be used a novel biomarker...
  14. pmc KIAA0101 interacts with BRCA1 and regulates centrosome number
    Zeina Kais
    Molecular, Cellular, and Development Program, Ohio State University, Columbus, OH, USA
    Mol Cancer Res 9:1091-9. 2011
    ..This study identifies KIAA0101 as a protein important for breast tumorigenesis, and as this factor has been reported as a UV repair factor, it may link the UV damage response to centrosome control...
  15. pmc Norepinephrine upregulates VEGF, IL-8, and IL-6 expression in human melanoma tumor cell lines: implications for stress-related enhancement of tumor progression
    Eric V Yang
    Department of Molecular Virology, Immunology and Medical Genetics, The Ohio State University Medical Center, Columbus, OH 43210, USA
    Brain Behav Immun 23:267-75. 2009
    ....
  16. pmc The lymphovascular embolus of inflammatory breast cancer expresses a stem cell-like phenotype
    Yi Xiao
    Department of Pathology, The Ohio State University College of Medicine, 129 Hamilton Hall, 1645 Neil Ave, Columbus, OH 43210 1218, USA
    Am J Pathol 173:561-74. 2008
    ..This stem cell-like phenotype may contribute to the aggressive nature of IBC but also may lend itself to selective targeting...
  17. pmc Precancerous stem cells can serve as tumor vasculogenic progenitors
    Rulong Shen
    Department of Pathology and Comprehensive Cancer Center, Ohio State University, Columbus, Ohio, USA
    PLoS ONE 3:e1652. 2008
    ..Our studies indicate that pCSCs can serve as tumor vasculogenic stem/progenitor cells (TVPCs), and may explain why anti-angiogenic cancer therapy trials are facing challenge...
  18. ncbi request reprint Atypical ductal hyperplasia presenting as pseudomicrocalcifications
    Henry C H Tsai
    Department of Pathology, UCLA School of Medicine, Los Angeles, California 90024, USA
    Breast J 9:39-40. 2003
    ..Upon excision, these turned out to be pseudomicrocalcifications created by the intraductal cellular proliferations of atypical ductal hyperplasia so dense as to create radiodensities...
  19. pmc Relationship of sialyl-Lewis(x/a) underexpression and E-cadherin overexpression in the lymphovascular embolus of inflammatory breast carcinoma
    Mary L Alpaugh
    Department of Pathology, University of California at Los Angeles School of Medicine, Los Angeles, California 90024, USA
    Am J Pathol 161:619-28. 2002
    ..Our findings support the cooperative relationship of sLe(x/a) underexpression and E-cadherin overexpression in the genesis of the lymphovascular embolus of IBC...
  20. ncbi request reprint Myoepithelial mRNA expression profiling reveals a common tumor-suppressor phenotype
    Sanford H Barsky
    Department of Pathology and Revlon UCLA Breast Center, UCLA School of Medicine, Los Angeles, CA 90024, USA
    Exp Mol Pathol 74:113-22. 2003
    ..Developmental genes were also differentially expressed (either over or underexpressed). These studies confirm our previous impression that human myoepithelial cells express a distinct tumor-suppressor phenotype...
  21. ncbi request reprint Angiosarcoma developing in a breast after conservation treatment for breast cancer
    Robert G Parker
    Department of Radiation Oncology, UCLA Medical Center, Los Angeles, California, USA
    Am J Clin Oncol 26:486-8. 2003
  22. ncbi request reprint Clinicopathologic analysis of sentinel lymph node mapping in early breast cancer
    Seung Hye Choi
    Department of Surgery, Revlon UCLA Breast Center, UCLA Medical Center, Los Angeles, California 90095, USA
    Breast J 9:153-62. 2003
    ....
  23. ncbi request reprint Anatomy of the nipple and breast ducts revisited
    Susan M Love
    Department of General Surgery, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, USA
    Cancer 101:1947-57. 2004
    ..Increasing interest in the intraductal approach to the breast has necessitated revisiting the anatomy of the breast...
  24. ncbi request reprint Semi-automated imaging system to quantitate Her-2/neu membrane receptor immunoreactivity in human breast cancer
    Aparna S Joshi
    BioImagene Inc, Suite 212, Cupertino, California 95014, USA
    Cytometry A 71:273-85. 2007
    ..Immunocytochemical methods for quantitating Her-2/neu immunoreactivity rest on subjective semi-quantitative interpretations with resulting interobserver, intraobserver, and fatigue variability...
  25. ncbi request reprint Novel interactions of vitamin E and estrogen in breast cancer
    Hilda Chamras
    Division of Hematology Oncology, Department of Medicine, University of California at Los Angeles, School of Medicine 90095 1678, USA
    Nutr Cancer 52:43-8. 2005
    ..This provides evidence that vitamin E may inhibit ER-positive cell growth by altering the cellular response to estrogen...