Research Topics

Genomes and Genes


C Barlow


Affiliation: The Salk Institute
Country: USA


  1. Barlow C, Dennery P, Shigenaga M, Smith M, Morrow J, Roberts L, et al. Loss of the ataxia-telangiectasia gene product causes oxidative damage in target organs. Proc Natl Acad Sci U S A. 1999;96:9915-9 pubmed
    ..These observations provide a mechanistic basis for the A-T phenotype and lay a rational foundation for therapeutic intervention. ..
  2. Barlow C, Ribaut Barassin C, Zwingman T, Pope A, Brown K, Owens J, et al. ATM is a cytoplasmic protein in mouse brain required to prevent lysosomal accumulation. Proc Natl Acad Sci U S A. 2000;97:871-6 pubmed
    ..These findings suggest that ATM may be important as a cytoplasmic protein in neurons and that its absence leads to abnormalities of cytoplasmic organelles reflected as an increase in lysosomal numbers. ..