GABOR BALAZSI

Summary

Affiliation: The University of Texas
Country: USA

Publications

  1. pmc Mapping the environmental fitness landscape of a synthetic gene circuit
    Dmitry Nevozhay
    Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
    PLoS Comput Biol 8:e1002480. 2012
  2. pmc The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest
    GABOR BALAZSI
    Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77054, USA
    Mol Syst Biol 4:225. 2008
  3. pmc Network inference and network response identification: moving genome-scale data to the next level of biological discovery
    Diogo F T Veiga
    Department of Systems Biology Unit 950, The University of Texas M D Anderson Cancer Center, Houston, TX, USA
    Mol Biosyst 6:469-80. 2010
  4. pmc A common repressor pool results in indeterminacy of extrinsic noise
    Michail Stamatakis
    Department of Chemical and Biomolecular Engineering, Rice University, Houston, Texas 77005, USA
    Chaos 21:047523. 2011
  5. doi request reprint Linearizer gene circuits with negative feedback regulation
    Dmitry Nevozhay
    UT M D Anderson Cancer Center, Houston, TX, USA
    Methods Mol Biol 734:81-100. 2011
  6. pmc Negative autoregulation linearizes the dose-response and suppresses the heterogeneity of gene expression
    Dmitry Nevozhay
    Department of Systems Biology, The University of Texas M D Anderson Cancer Center, Houston, TX 77054, USA
    Proc Natl Acad Sci U S A 106:5123-8. 2009
  7. pmc Unraveling the regulatory connections between two controllers of breast cancer cell fate
    Jinho Lee
    Department of Systems Biology Unit 950, The University of Texas MD Anderson Cancer Center, Houston, TX 77054, USA Department of Bioengineering, Rice University, Houston, TX 77005, USA
    Nucleic Acids Res 42:6839-49. 2014
  8. pmc The interplay of multiple feedback loops with post-translational kinetics results in bistability of mycobacterial stress response
    Abhinav Tiwari
    Department of Bioengineering, Rice University, MS 142, 6100 Main St, Houston, TX 77005, USA
    Phys Biol 7:036005. 2010
  9. pmc Transferring a synthetic gene circuit from yeast to mammalian cells
    Dmitry Nevozhay
    Department of Systems Biology Unit 950, The University of Texas MD Anderson Cancer Center, 7435 Fannin Street, Houston, Texas 77054, USA
    Nat Commun 4:1451. 2013
  10. pmc Abortive autophagy induces endoplasmic reticulum stress and cell death in cancer cells
    Sofie Claerhout
    Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
    PLoS ONE 7:e39400. 2012

Collaborators

Detail Information

Publications11

  1. pmc Mapping the environmental fitness landscape of a synthetic gene circuit
    Dmitry Nevozhay
    Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
    PLoS Comput Biol 8:e1002480. 2012
    ....
  2. pmc The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest
    GABOR BALAZSI
    Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77054, USA
    Mol Syst Biol 4:225. 2008
    ..tuberculosis infection, a condition found in two billion people worldwide...
  3. pmc Network inference and network response identification: moving genome-scale data to the next level of biological discovery
    Diogo F T Veiga
    Department of Systems Biology Unit 950, The University of Texas M D Anderson Cancer Center, Houston, TX, USA
    Mol Biosyst 6:469-80. 2010
    ..Finally, we conclude with an outlook on what is still missing from these approaches and what may be ahead on the road to biological discovery...
  4. pmc A common repressor pool results in indeterminacy of extrinsic noise
    Michail Stamatakis
    Department of Chemical and Biomolecular Engineering, Rice University, Houston, Texas 77005, USA
    Chaos 21:047523. 2011
    ..Rather, they exert negative regulation on each other and thus extrinsic noise cannot be determined by the currently established method...
  5. doi request reprint Linearizer gene circuits with negative feedback regulation
    Dmitry Nevozhay
    UT M D Anderson Cancer Center, Houston, TX, USA
    Methods Mol Biol 734:81-100. 2011
    ....
  6. pmc Negative autoregulation linearizes the dose-response and suppresses the heterogeneity of gene expression
    Dmitry Nevozhay
    Department of Systems Biology, The University of Texas M D Anderson Cancer Center, Houston, TX 77054, USA
    Proc Natl Acad Sci U S A 106:5123-8. 2009
    ..These findings have important implications for gene expression control in eukaryotic cells, including the design of synthetic expression systems...
  7. pmc Unraveling the regulatory connections between two controllers of breast cancer cell fate
    Jinho Lee
    Department of Systems Biology Unit 950, The University of Texas MD Anderson Cancer Center, Houston, TX 77054, USA Department of Bioengineering, Rice University, Houston, TX 77005, USA
    Nucleic Acids Res 42:6839-49. 2014
    ....
  8. pmc The interplay of multiple feedback loops with post-translational kinetics results in bistability of mycobacterial stress response
    Abhinav Tiwari
    Department of Bioengineering, Rice University, MS 142, 6100 Main St, Houston, TX 77005, USA
    Phys Biol 7:036005. 2010
    ..We predict that overexpression or deletion of RseA, the key element controlling the ultrasensitive response, can eliminate bistability...
  9. pmc Transferring a synthetic gene circuit from yeast to mammalian cells
    Dmitry Nevozhay
    Department of Systems Biology Unit 950, The University of Texas MD Anderson Cancer Center, 7435 Fannin Street, Houston, Texas 77054, USA
    Nat Commun 4:1451. 2013
    ..The steps we have taken should be generally relevant for transferring any gene circuit from yeast into mammalian cells...
  10. pmc Abortive autophagy induces endoplasmic reticulum stress and cell death in cancer cells
    Sofie Claerhout
    Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
    PLoS ONE 7:e39400. 2012
    ..Our results demonstrate that the coatomer complex is essential for productive autophagy and cellular survival, and thus inhibition of COPI members may promote cell death of cancer cells when apoptosis is compromised...
  11. doi request reprint Statistical evaluation of genetic footprinting data
    GABOR BALAZSI
    Department of Systems Biology Unit 950, University of Texas M D Anderson Cancer Center, Houston, TX, USA
    Methods Mol Biol 416:355-9. 2008
    ....

Research Grants1

  1. Connecting the selection of noisy gene expression deviants to genetic evolution
    GABOR BALAZSI; Fiscal Year: 2009
    ..This will enable the discovery of yet unknown mechanisms underlying the emergence of drug resistance, which might substantially improve future therapeutic strategies for combating microbial infections as well as cancer. ..