Research Topics
Species | Michael T BaileySummaryAffiliation: The Ohio State University Country: USA Publications
Research Grants
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Detail Information
Publications
Stress induces the translocation of cutaneous and gastrointestinal microflora to secondary lymphoid organs of C57BL/6 miceMichael T Bailey
Laboratory of Neuroendocrine Immunology, Section of Oral Biology, College of Dentistry, The Ohio State University, 305 W 12th Ave, Columbus, OH 43210, USA
J Neuroimmunol 171:29-37. 2006..Our results indicate that psychological components of social stress facilitate the translocation of indigenous bacteria into the host, thus identifying an additional facet through which stressors may impact health...- Intestinal microbial patterns of the common marmoset and rhesus macaqueMichael T Bailey
Harlow Primate Laboratory, 22 N Charter Street, University of Wisconsin, Madison, WI 53715, USA
Comp Biochem Physiol A Mol Integr Physiol 133:379-88. 2002.... 
Stressor exposure disrupts commensal microbial populations in the intestines and leads to increased colonization by Citrobacter rodentiumMichael T Bailey
Division of Oral Biology, College of Dentistry, The Ohio State University, Columbus, Ohio 43210, USA
Infect Immun 78:1509-19. 2010..Together, these data demonstrate that a prolonged stressor can significantly change the composition of the intestinal microbiota and suggest that this disruption of the microbiota increases susceptibility to an enteric pathogen...- Prenatal stress alters bacterial colonization of the gut in infant monkeysMichael T Bailey
Harlow Primate Laboratory, University of Wisconsin, Madison, Wisconsin, USA
J Pediatr Gastroenterol Nutr 38:414-21. 2004..The hypothesis that prenatal stress lowers the levels of protective microflora and increases the risk for postpartum Gram-negative pathogens was tested in infant monkeys... - Physical defeat reduces the sensitivity of murine splenocytes to the suppressive effects of corticosteroneMichael T Bailey
Section of Oral Biology, College of Dentistry, The Ohio State University, Columbus, OH 43218, USA
Brain Behav Immun 18:416-24. 2004..This study indicates that exposure to a stressful environment in the absence of physical attack does not reduce the sensitivity of murine splenocytes to the suppressive effects of corticosterone... 
Photoperiod modulates gut bacteria composition in male Siberian hamsters (Phodopus sungorus)Michael T Bailey
Section of Oral Biology, College of Dentistry, The Ohio State University, Columbus, OH 43210, USA
Brain Behav Immun 24:577-84. 2010..These data indicate that the intestinal microbiota are responsive to changes in photoperiod and suggest that these changes may in part influence photoperiodic changes in body and fat masses...- Social stress enhances IL-1beta and TNF-alpha production by Porphyromonas gingivalis lipopolysaccharide-stimulated CD11b+ cellsMichael T Bailey
Section of Oral Biology, College of Dentistry, The Ohio State University, Columbus, OH 43210, United States
Physiol Behav 98:351-8. 2009..This study demonstrates that social stress enhances the inflammatory response to an oral pathogen and could provide a critical clue in the reported associations between stress, inflammation, and oral pathogens... - Repeated social defeat increases the bactericidal activity of splenic macrophages through a Toll-like receptor-dependent pathwayMichael T Bailey
Section of Oral Biology, College of Dentistry, The Ohio State University, 305 W 12th Ave, Columbus, OH 43210, USA
Am J Physiol Regul Integr Comp Physiol 293:R1180-90. 2007..These data indicate that SDR increases TLR expression, which in turn enhances the bactericidal activity of splenic macrophages, in part by increasing pathways responsible for reactive oxygen and nitrogen intermediate production... - Interleukin-1 receptor type 1-deficient mice fail to develop social stress-associated glucocorticoid resistance in the spleenHarald Engler
Section of Oral Biology, College of Dentistry, The Ohio State University, Columbus, OH 43210, USA
Psychoneuroendocrinology 33:108-17. 2008..These findings suggest that IL-1 plays a critical role in the development of the social stress-associated GC resistance in the murine spleen... - Repeated social defeat causes increased anxiety-like behavior and alters splenocyte function in C57BL/6 and CD-1 miceSteven G Kinsey
Department of Psychology, The Ohio State University, Columbus, OH 43210, USA
Brain Behav Immun 21:458-66. 2007..These data indicate that social disruption stress causes an increase in anxiety-like behaviors, but not depressive-like behaviors... - The inflammatory response to social defeat is increased in older miceSteven G Kinsey
Section of Oral Biology, College of Dentistry, The Ohio State University, Columbus, OH 43210 USA
Physiol Behav 93:628-36. 2008..These data indicated that repeated social defeat results in a proinflammatory state that is exacerbated in older mice. The implications of these data are noteworthy, given the strong role of inflammation in many age-related diseases... - β-Adrenergic receptor antagonism prevents anxiety-like behavior and microglial reactivity induced by repeated social defeatEric S Wohleb
Division of Oral Biology, Department of Molecular Virology, Immunology and Medical Genetics, The Ohio State University, Columbus, Ohio 43210, USA
J Neurosci 31:6277-88. 2011..These findings indicate that repeated social defeat-induced anxiety-like behavior and enhanced reactivity of microglia was dependent on activation of β-adrenergic and IL-1 receptors... - Stressor-induced increase in microbicidal activity of splenic macrophages is dependent upon peroxynitrite productionRebecca G Allen
Integrated Biomedical Sciences Graduate Program, Wexner Medical Center at The Ohio State University, Columbus, Ohio, USA
Infect Immun 80:3429-37. 2012..coli demonstrates that peroxynitrite mediates the stressor-induced increase in bacterial killing... - Stress and the anti-influenza immune response: repeated social defeat augments clonal expansion of CD8(+)T cells during primary influenza A viral infectionJacqueline W Mays
The Ohio State University, College of Dentistry, Section of Oral Biology, Columbus, OH 43218 2357, USA
J Neuroimmunol 243:34-42. 2012..These data demonstrate neuroendocrine modification of the lung microenvironment and increased antigen-specific T cell activation, clonal expansion and viral control in stress-exposed mice... - Immunogenic dendritic cells primed by social defeat enhance adaptive immunity to influenza A virusNicole D Powell
Section of Oral Biology, College of Dentistry, The Ohio State University, Columbus, OH, USA
Brain Behav Immun 25:46-52. 2011..These data demonstrate that repeated social defeat is a significant environmental influence on immunogenic DC activation and function... - Influenza virus-specific immunological memory is enhanced by repeated social defeatJacqueline W Mays
Section of Oral Biology, College of Dentistry, The Ohio State University, Columbus, OH 43210, USA
J Immunol 184:2014-25. 2010.... - The intestinal microbiota are necessary for stressor-induced enhancement of splenic macrophage microbicidal activityRebecca G Allen
Integrated Biomedical Sciences Graduate Program, College of Medicine, The Ohio State University, Columbus, OH 43210, USA
Brain Behav Immun 26:371-82. 2012..This study demonstrates that the microbiota play a crucial role in stressor-induced immunoenhancement... - Exposure to a social stressor alters the structure of the intestinal microbiota: implications for stressor-induced immunomodulationMichael T Bailey
Division of Oral Biology, College of Dentistry, The Ohio State University, Columbus, OH 43210, United States
Brain Behav Immun 25:397-407. 2011..These data show that exposure to SDR significantly affects bacterial populations in the intestines, and remarkably also suggest that the microbiota are necessary for stressor-induced increases in circulating cytokines... - Effects of repeated social stress on leukocyte distribution in bone marrow, peripheral blood and spleenHarald Engler
Laboratory of Neuroendocrine Immunology, Section of Oral Biology, College of Dentistry, The Ohio State University Health Sciences Center, Columbus, OH 43210, USA
J Neuroimmunol 148:106-15. 2004.... - Tissue-specific alterations in the glucocorticoid sensitivity of immune cells following repeated social defeat in miceHarald Engler
Laboratory of Neuroendocrine Immunology, Section of Oral Biology, College of Dentistry, The Ohio State University Health Sciences Center, Columbus, OH 43210, USA
J Neuroimmunol 163:110-9. 2005.... - Social disruption induces lung inflammationJennifer M Curry
Division of Pulmonary, Allergy, Critical Care, and Sleep Medicine, Department of Internal Medicine, The Ohio State University, Columbus, OH 43210, USA
Brain Behav Immun 24:394-402. 2010..These data support previous findings of an inflammatory environment induced by SDR. We demonstrate that this effect also occurs in the pulmonary milieu and in the absence of an inflammatory stimulus... - Food restriction compromises immune memory in deer mice (Peromyscus maniculatus) by reducing spleen-derived antibody-producing B cell numbersLynn B Martin
Department of Psychology, Ohio State University, Columbus, Ohio 43210, USA
Physiol Biochem Zool 81:366-72. 2008..These results further indicate that maintenance of immune memory is expensive and may be subject to trade-offs with other physiological processes... - Social stress enhances allergen-induced airway inflammation in mice and inhibits corticosteroid responsiveness of cytokine productionMichael T Bailey
Department of Oral Biology and Institute for Behavioral Medicine Research, Ohio State University, Columbus, OH 43210, USA
J Immunol 182:7888-96. 2009..We speculate that these effects were mediated at least in part by impaired glucocorticoid receptor expression and function... - Endometriosis is associated with an altered profile of intestinal microflora in female rhesus monkeysMichael T Bailey
University of Wisconsin, Harlow Center for Biological Psychology, 22 N Charter Street, Madison, WI 53715, USA
Hum Reprod 17:1704-8. 2002..A second study assessed the prevalence of intestinal inflammation in female monkeys to determine whether endometriosis is associated with an increased likelihood of intestinal inflammation... - Minocycline attenuates lipopolysaccharide (LPS)-induced neuroinflammation, sickness behavior, and anhedoniaChristopher J Henry
Department of Molecular Virology, Immunology and Medical Genetics, The Ohio State University, 333 W, 10th Ave, Columbus, OH 43210, USA
J Neuroinflammation 5:15. 2008..The purpose of this study was to determine if minocycline, an anti-inflammatory agent and purported microglial inhibitor, attenuates lipopolysaccharide (LPS)-induced neuroinflammation, sickness behavior, and anhedonia... - Stressor-induced alterations of adaptive immunity to vaccination and viral pathogensNicole D Powell
Division of Oral Biology, College of Dentistry, The Ohio State University, Columbus, OH 43210, USA
Immunol Allergy Clin North Am 31:69-79. 2011..This review provides a brief overview of the immune response to commonly used vaccines and the impact that stress can have on vaccine-specific immunity... - Subordinate social status modulates the vulnerability to the immunological effects of social stressRonit Avitsur
School of Behavioral Sciences, The Academic College of Tel Aviv Yaffo, Yaffo, Israel
Psychoneuroendocrinology 32:1097-105. 2007..This study further demonstrated the complexity of factors playing a role in mediating the physiological response to social stress resulting in considerable individual differences in the response to stress...
Research Grants
- Impact of Social Stress on TLR4-Induced Microbicidal Activity of CD11b+ CellsMichael Bailey; Fiscal Year: 2007..Defining the stress-induced cellular changes that enhance immune functioning could stimulate new therapeutic approaches to treating infectious diseases. ..