L Eugene Arnold

Summary

Affiliation: The Ohio State University
Country: USA

Publications

  1. ncbi request reprint Zinc in attention-deficit/hyperactivity disorder
    L Eugene Arnold
    Department of Psychiatry, Ohio State University, Columbus, OH 43074, USA
    J Child Adolesc Psychopharmacol 15:619-27. 2005
  2. pmc Research Units of Pediatric Psychopharmacology (RUPP) autism network randomized clinical trial of parent training and medication: one-year follow-up
    L Eugene Arnold
    Nisonger Center, Ohio State University, Sunbury, OH 43074, USA
    J Am Acad Child Adolesc Psychiatry 51:1173-84. 2012
  3. pmc Phenomenology of bipolar disorder not otherwise specified in youth: a comparison of clinical characteristics across the spectrum of manic symptoms
    Danella Hafeman
    Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Bipolar Disord 15:240-52. 2013
  4. pmc Pediatric bipolar spectrum disorder and ADHD: comparison and comorbidity in the LAMS clinical sample
    L Eugene Arnold
    Division of Child and Adolescent Psychiatry, Department of Psychiatry, Ohio State University, 1670 Upham Drive, Columbus, OH 43210, USA
    Bipolar Disord 13:509-21. 2011
  5. pmc Characteristics of children with elevated symptoms of mania: the Longitudinal Assessment of Manic Symptoms (LAMS) study
    Robert L Findling
    Department of Psychiatry, Division of Child and Adolescent Psychiatry, Case Western Reserve University, Cleveland, Ohio, USA
    J Clin Psychiatry 71:1664-72. 2010
  6. pmc Cognitive effects of risperidone in children with autism and irritable behavior
    Michael G Aman
    Nisonger Center, Ohio State University, Columbus, OH, USA
    J Child Adolesc Psychopharmacol 18:227-36. 2008
  7. pmc Zinc for attention-deficit/hyperactivity disorder: placebo-controlled double-blind pilot trial alone and combined with amphetamine
    L Eugene Arnold
    The Nisonger Center, Ohio State University, Columbus, Ohio, USA
    J Child Adolesc Psychopharmacol 21:1-19. 2011
  8. pmc Pediatric bipolar disorder and ADHD: family history comparison in the LAMS clinical sample
    L Eugene Arnold
    Division of Child and Adolescent Psychiatry, Department of Psychiatry, Ohio State University, Columbus, OH, United States
    J Affect Disord 141:382-9. 2012
  9. pmc What differentiates children visiting outpatient mental health services with bipolar spectrum disorder from children with other psychiatric diagnoses?
    Mary A Fristad
    Division of Child and Adolescent Psychiatry, Department of Psychiatry, Ohio State University, Columbus, OH 43210, USA
    Bipolar Disord 14:497-506. 2012
  10. ncbi request reprint Positive effects of methylphenidate on inattention and hyperactivity in pervasive developmental disorders: an analysis of secondary measures
    David J Posey
    Department of Psychiatry, Indiana University School of Medicine, Indianapolis, Indiana, USA
    Biol Psychiatry 61:538-44. 2007

Detail Information

Publications84

  1. ncbi request reprint Zinc in attention-deficit/hyperactivity disorder
    L Eugene Arnold
    Department of Psychiatry, Ohio State University, Columbus, OH 43074, USA
    J Child Adolesc Psychopharmacol 15:619-27. 2005
    ..The aim of this study was to review the published evidence for a role of zinc nutrition in attention-deficit/hyperactivity disorder (ADHD)...
  2. pmc Research Units of Pediatric Psychopharmacology (RUPP) autism network randomized clinical trial of parent training and medication: one-year follow-up
    L Eugene Arnold
    Nisonger Center, Ohio State University, Sunbury, OH 43074, USA
    J Am Acad Child Adolesc Psychiatry 51:1173-84. 2012
    ..The COMB treatment had shown a significant advantage for child behavioral noncompliance (p = .006, d = 0.34), irritability (p = .01, d = 0.48), and hyperactivity/noncompliance (p = .04, d = 0.55) with a lower medication dose...
  3. pmc Phenomenology of bipolar disorder not otherwise specified in youth: a comparison of clinical characteristics across the spectrum of manic symptoms
    Danella Hafeman
    Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Bipolar Disord 15:240-52. 2013
    ....
  4. pmc Pediatric bipolar spectrum disorder and ADHD: comparison and comorbidity in the LAMS clinical sample
    L Eugene Arnold
    Division of Child and Adolescent Psychiatry, Department of Psychiatry, Ohio State University, 1670 Upham Drive, Columbus, OH 43210, USA
    Bipolar Disord 13:509-21. 2011
    ..To compare attention-deficit hyperactivity disorder (ADHD), bipolar spectrum disorders (BPSDs), and comorbidity in the Longitudinal Assessment of Manic Symptoms (LAMS) study...
  5. pmc Characteristics of children with elevated symptoms of mania: the Longitudinal Assessment of Manic Symptoms (LAMS) study
    Robert L Findling
    Department of Psychiatry, Division of Child and Adolescent Psychiatry, Case Western Reserve University, Cleveland, Ohio, USA
    J Clin Psychiatry 71:1664-72. 2010
    ..This article describes the initial demographic information, diagnostic and symptom prevalence, and medication exposure for the LAMS cohort that will be followed longitudinally...
  6. pmc Cognitive effects of risperidone in children with autism and irritable behavior
    Michael G Aman
    Nisonger Center, Ohio State University, Columbus, OH, USA
    J Child Adolesc Psychopharmacol 18:227-36. 2008
    ..The objective of this research was to explore the effects of risperidone on cognitive processes in children with autism and irritable behavior...
  7. pmc Zinc for attention-deficit/hyperactivity disorder: placebo-controlled double-blind pilot trial alone and combined with amphetamine
    L Eugene Arnold
    The Nisonger Center, Ohio State University, Columbus, Ohio, USA
    J Child Adolesc Psychopharmacol 21:1-19. 2011
    ..To explore effects of zinc supplementation in American children with attention-deficit/hyperactivity disorder (ADHD). Mideastern trials reported significant benefit from 13-40 mg elemental zinc as the sulfate...
  8. pmc Pediatric bipolar disorder and ADHD: family history comparison in the LAMS clinical sample
    L Eugene Arnold
    Division of Child and Adolescent Psychiatry, Department of Psychiatry, Ohio State University, Columbus, OH, United States
    J Affect Disord 141:382-9. 2012
    ..Transgenerational association of bipolar spectrum disorder (BPSD) and attention deficit/hyperactivity disorder (ADHD) has been reported, but inconclusively...
  9. pmc What differentiates children visiting outpatient mental health services with bipolar spectrum disorder from children with other psychiatric diagnoses?
    Mary A Fristad
    Division of Child and Adolescent Psychiatry, Department of Psychiatry, Ohio State University, Columbus, OH 43210, USA
    Bipolar Disord 14:497-506. 2012
    ....
  10. ncbi request reprint Positive effects of methylphenidate on inattention and hyperactivity in pervasive developmental disorders: an analysis of secondary measures
    David J Posey
    Department of Psychiatry, Indiana University School of Medicine, Indianapolis, Indiana, USA
    Biol Psychiatry 61:538-44. 2007
    ....
  11. ncbi request reprint Acetyl-L-carnitine (ALC) in attention-deficit/hyperactivity disorder: a multi-site, placebo-controlled pilot trial
    L Eugene Arnold
    The Ohio State University Nisonger Center, Columbus, OH, USA
    J Child Adolesc Psychopharmacol 17:791-802. 2007
    ..Trials in Down's syndrome, migraine, and Alzheimer's disease showed benefit for attention. A preliminary trial in ADHD using L-carnitine reported significant benefit...
  12. pmc Medication and parent training in children with pervasive developmental disorders and serious behavior problems: results from a randomized clinical trial
    Michael G Aman
    The Nisonger Center UCEDD, Ohio State University, Columbus, OH 43210 1257, USA
    J Am Acad Child Adolesc Psychiatry 48:1143-54. 2009
    ..We tested whether combined treatment (COMB) with risperidone and parent training (PT) in behavior management is superior to medication alone (MED) in improving severe behavioral problems in children with PDDs...
  13. pmc EEG neurofeedback for ADHD: double-blind sham-controlled randomized pilot feasibility trial
    L Eugene Arnold
    The Ohio State University, Columbus, OH, USA
    J Atten Disord 17:410-9. 2013
    ....
  14. pmc Placebo-controlled pilot trial of mecamylamine for treatment of autism spectrum disorders
    L Eugene Arnold
    Nisonger Center, The Ohio State University, Columbus, OH 43210, USA
    J Child Adolesc Psychopharmacol 22:198-205. 2012
    ..To explore possible benefits of a nicotinic acetylcholine receptor (nAChR) agent for autistic symptoms based on postmortem observation of nAChR abnormalities (deficient α4β2 nAChRs, excess α7 nAChRs) in brains of patients with autism...
  15. pmc Moderators, mediators, and other predictors of risperidone response in children with autistic disorder and irritability
    L Eugene Arnold
    Department of Psychiatry, Ohio State University, Columbus, Ohio, USA
    J Child Adolesc Psychopharmacol 20:83-93. 2010
    ..2 in favor of risperidone on the main outcome measure in an 8-week double-blind, placebo-controlled trial for irritability in autistic disorder. This paper explores moderators and mediators of this effect...
  16. pmc Nutritional and safety outcomes from an open-label micronutrient intervention for pediatric bipolar spectrum disorders
    Elisabeth A Frazier
    Department of Psychiatry, Department of Human Nutrition, The Ohio State University, Columbus, Ohio
    J Child Adolesc Psychopharmacol 23:558-67. 2013
    ....
  17. ncbi request reprint Risperidone for the core symptom domains of autism: results from the study by the autism network of the research units on pediatric psychopharmacology
    Christopher J McDougle
    Department of Psychiatry, Indiana University School of Medicine, Indianapolis, IN 46202 4800, USA
    Am J Psychiatry 162:1142-8. 2005
    ..The authors report on whether risperidone improves the core symptoms of autism, social and communication impairment and repetitive and stereotyped behavior...
  18. doi request reprint Attention-deficit/hyperactivity disorder: dietary and nutritional treatments
    L Eugene Arnold
    Nisonger Center, Ohio State University, McCampbell 395E, 1581 Dodd Drive, Columbus, OH 43210, USA
    Child Adolesc Psychiatr Clin N Am 22:381-402, v. 2013
    ..There is a need to flesh out the evidence base, which could be done cost effectively for supplements or off-label agents that are amenable to placebo control. ..
  19. pmc Serum ferritin and amphetamine response in youth with attention-deficit/hyperactivity disorder
    Chadi Calarge
    Department of Psychiatry, The University of Iowa Carver College of Medicine, Iowa City, Iowa 52242, USA
    J Child Adolesc Psychopharmacol 20:495-502. 2010
    ..The study aim was to explore whether iron stores, as reflected by serum ferritin concentration, predicted response to psychostimulants...
  20. doi request reprint Vestibular Stimulation for ADHD: randomized controlled trial of Comprehensive Motion Apparatus
    David L Clark
    Ohio State University, Ohio, USA
    J Atten Disord 11:599-611. 2008
    ..This research evaluates effects of vestibular stimulation by Comprehensive Motion Apparatus (CMA) in ADHD...
  21. ncbi request reprint Delinquent behavior and emerging substance use in the MTA at 36 months: prevalence, course, and treatment effects
    Brooke S G Molina
    Department of Psychiatry, University of Pittsburgh School of Medicine, 3811 O Hara Street, Pittsburgh, PA 15213, USA
    J Am Acad Child Adolesc Psychiatry 46:1028-40. 2007
    ....
  22. pmc Treatment of inattention, overactivity, and impulsiveness in autism spectrum disorders
    Michael G Aman
    Department of Psychology, Ohio State University, 225 Psychology Building, 1835 Neil Avenue, Columbus, OH 43210, USA
    Child Adolesc Psychiatr Clin N Am 17:713-38, vii. 2008
    ..Evidence for efficacy seems weakest for newer antidepressants, anxiolytics, and mood stabilizers...
  23. doi request reprint Feasibility of a nutritional supplement as treatment for pediatric bipolar spectrum disorders
    Elisabeth A Frazier
    Department of Psychiatry, The Ohio State University, Columbus, OH, USA
    J Altern Complement Med 18:678-85. 2012
    ..This open-label study explored the feasibility of testing therapeutic effects of a multinutrient supplement, EMPowerplus™ (EMP+), for pediatric BPSD...
  24. pmc Psychopharmacological and other treatments in preschool children with attention-deficit/hyperactivity disorder: current evidence and practice
    Jaswinder K Ghuman
    Department of Psychiatry, University of Arizona, Tucson, Arizona 85724 5002, USA
    J Child Adolesc Psychopharmacol 18:413-47. 2008
    ..This article reviews rational approaches to treating attention-deficit/hyperactivity disorder (ADHD) in preschool children, including pharmacological and nonpharmacological treatments. Implications for clinical practice are discussed...
  25. ncbi request reprint Methylphenidate treatment in children with borderline IQ and mental retardation: analysis of three aggregated studies
    Michael G Aman
    Department of Psychiatry, School of Medicine, University of Auckland, Auckland, New Zealand
    J Child Adolesc Psychopharmacol 13:29-40. 2003
    ..To determine response of low-IQ children with attention deficit hyperactivity disorder (ADHD) symptoms to methylphenidate (MPH)...
  26. ncbi request reprint A double-blind, placebo-controlled withdrawal trial of dexmethylphenidate hydrochloride in children with attention deficit hyperactivity disorder
    L Eugene Arnold
    Ohio State University, Columbus, Ohio 43210 1296, USA
    J Child Adolesc Psychopharmacol 14:542-54. 2004
    ..This study complements that report by studying the effect of placebo-controlled discontinuation and retesting the duration of action...
  27. ncbi request reprint Nine months of multicomponent behavioral treatment for ADHD and effectiveness of MTA fading procedures
    L Eugene Arnold
    The Ohio State University, Columbus, Ohio, USA
    J Abnorm Child Psychol 32:39-51. 2004
    ....
  28. ncbi request reprint Parent-defined target symptoms respond to risperidone in RUPP autism study: customer approach to clinical trials
    L Eugene Arnold
    Ohio State University, 479 S Galena Road, Sunbury, OH 43074, USA
    J Am Acad Child Adolesc Psychiatry 42:1443-50. 2003
    ..A consumer-oriented efficacy assessment in clinical trials should measure changes in chief complaint and consumer request (symptoms of most concern to patient/caregiver), which may be diluted in change scores of multisymptom scales...
  29. ncbi request reprint Acute and long-term safety and tolerability of risperidone in children with autism
    Michael G Aman
    The Nisonger Center, Ohio State University, Columbus, Ohio 43210 1296, USA
    J Child Adolesc Psychopharmacol 15:869-84. 2005
    ..Most AEs were mild to moderate and failed to interfere with therapeutic changes; there were no unanticipated AEs. The side effects of most concern were somnolence and weight gain...
  30. ncbi request reprint Validity of the autism diagnostic interview-revised
    Luc Lecavalier
    Nisonger Center, The Ohio State University, Columbus, USA
    Am J Ment Retard 111:199-215. 2006
    ..They indicated some similarities between constructs, but also that the ADI-R measures autism in a unique fashion...
  31. ncbi request reprint Effects of ethnicity on treatment attendance, stimulant response/dose, and 14-month outcome in ADHD
    L Eugene Arnold
    Department of Psychiatry, Ohio State University, USA
    J Consult Clin Psychol 71:713-27. 2003
    ..Treatment for lower socioeconomic status minority children, especially if comorbid, should combine medication and behavioral treatment...
  32. ncbi request reprint A review of atomoxetine effects in young people with developmental disabilities
    Michael G Aman
    The Nisonger Center UCEDD, Ohio State University, McCampbell Hall, 1581 Dodd Dr, Columbus, OH 43210, United States Electronic address
    Res Dev Disabil 35:1412-24. 2014
    ..Splitting the dose initially, starting below the recommended starting dose, and titrating slowly may prevent or ameliorate side effects. Patience is needed for the slow build-up of benefit...
  33. pmc Artificial food colors and attention-deficit/hyperactivity symptoms: conclusions to dye for
    L Eugene Arnold
    Department of Psychiatry, The Ohio State University, Columbus, OH 43210, USA
    Neurotherapeutics 9:599-609. 2012
    ..A table clarifying the Food and Drug Administration and international naming systems for AFCs, with cross-referencing, is provided...
  34. ncbi request reprint Current status of neurofeedback for attention-deficit/hyperactivity disorder
    Nicholas Lofthouse
    Department of Psychiatry, The Ohio State University, 1670 Upham Drive, Columbus, OH 43210, USA
    Curr Psychiatry Rep 14:536-42. 2012
    ..Most recently, a collaborative NF research group has been planning a definitive double-blind well-controlled trial...
  35. pmc A review of complementary and alternative treatments for autism spectrum disorders
    Nicholas Lofthouse
    Department of Psychiatry, The Ohio State University, 1670 Upham Drive, Columbus, OH 43210, USA
    Autism Res Treat 2012:870391. 2012
    ..We conclude this paper with recommendations for future research and ten clinical recommendations for practitioners...
  36. ncbi request reprint Parent satisfaction in a multi-site acute trial of risperidone in children with autism: a social validity study
    Elaine Tierney
    Department of Psychiatry, Kennedy Krieger Institute, Baltimore, MD, USA
    Psychopharmacology (Berl) 191:149-57. 2007
    ..Designing studies that consider the consumer's perspective will help to forge a better alliance between participants and researchers...
  37. ncbi request reprint Treating attention-deficit/hyperactivity disorder with a stimulant transdermal patch: the clinical art
    L Eugene Arnold
    Department of Psychiatry, Ohio State University, Columbus, Ohio, USA
    Pediatrics 120:1100-6. 2007
    ..This article summarizes clinical principles that physicians may find useful in managing this new addition to the attention-deficit/hyperactivity disorder treatment armamentarium...
  38. pmc The treatment of severe child aggression (TOSCA) study: Design challenges
    Cristan A Farmer
    Nisonger Center, Ohio State University, Columbus, USA
    Child Adolesc Psychiatry Ment Health 5:36. 2011
    ..abstract:..
  39. doi request reprint A review of neurofeedback treatment for pediatric ADHD
    Nicholas Lofthouse
    Department of Psychiatry, The Ohio State University, 1670 Upham Drive, Columbus, OH 43210 1250, USA
    J Atten Disord 16:351-72. 2012
    ..The aim of this paper was to review all randomized published trials and unpublished conference presentations on the neurofeedback (NF) treatment of pediatric ADHD, and their relevance, strengths, and limitations...
  40. ncbi request reprint Empirical evaluation of the generalizability of the sample from the multimodal treatment study for ADHD
    Jack Stevens
    Department of Pediatrics, The Ohio State University, 899 East Broad Street, 3rd Floor, Columbus, OH 43205, USA
    Adm Policy Ment Health 34:221-32. 2007
    ..On the whole, we found no compelling evidence against the representativeness of the MTA sample, but the limited power from MECA and NHANES may have lead to noteworthy differences between datasets being statistically nonsignificant...
  41. pmc Early-onset bipolar spectrum disorders: diagnostic issues
    Stephanie Danner
    Ohio State University, Columbus, OH, USA
    Clin Child Fam Psychol Rev 12:271-93. 2009
    ..Research findings concerning these challenges and relevant recommendations are offered. Areas for further research to guide clinicians' assessment of children with early-onset BPSD are highlighted...
  42. ncbi request reprint Atomoxetine for hyperactivity in autism spectrum disorders: placebo-controlled crossover pilot trial
    L Eugene Arnold
    The authors are with Ohio State University s Nisonger Center, Columbus, OH 43210, USA
    J Am Acad Child Adolesc Psychiatry 45:1196-205. 2006
    ..To explore placebo-controlled efficacy and safety of atomoxetine (ATX) for attention-deficit/hyperactivity disorder (ADHD) symptoms in children with autism spectrum disorders (ASD)...
  43. ncbi request reprint Serum zinc correlates with parent- and teacher- rated inattention in children with attention-deficit/hyperactivity disorder
    L Eugene Arnold
    Department of Psychiatry, Ohio State University, Columbus, Ohio 43074, USA
    J Child Adolesc Psychopharmacol 15:628-36. 2005
    ..Previous reports of zinc in ADHD, including two positive clinical trials of supplementation, have come mainly from countries and cultures with different diets and/or socioeconomic realities...
  44. ncbi request reprint Ethical issues in child psychopharmacology research and practice: emphasis on preschoolers
    Lacramioara Spetie
    Department of Psychiatry, Ohio State University, 1670 Upham Drive, Columbus, OH 43210, USA
    Psychopharmacology (Berl) 191:15-26. 2007
    ..Within the past few decades, several ethical principles guiding pediatric psychopharmacological research have been developed. The same principles could effectively guide the treatment of these patients...
  45. ncbi request reprint Atomoxetine alone or combined with fluoxetine for treating ADHD with comorbid depressive or anxiety symptoms
    Christopher J Kratochvil
    Department of Psychiatry, Nebraska Medical Center, Omaha 68198 5581, USA
    J Am Acad Child Adolesc Psychiatry 44:915-24. 2005
    ..The authors assessed the safety and effectiveness of atomoxetine monotherapy compared with combined atomoxetine/fluoxetine therapy in a population of children and adolescents with ADHD and concurrent symptoms of depression or anxiety...
  46. ncbi request reprint The role of children's ethnicity in the relationship between teacher ratings of attention-deficit/hyperactivity disorder and observed classroom behavior
    Jeffrey N Epstein
    Department of Psychiatry, Duke University Medical Center, Durham, NC 27710, USA
    J Consult Clin Psychol 73:424-34. 2005
    ..Differences in classroom behavior were attenuated when the behavior of an average child in the classroom was taken into account. Multiple explanations for this pattern of results are discussed...
  47. doi request reprint Dietary and nutritional treatments for attention-deficit/hyperactivity disorder: current research support and recommendations for practitioners
    Elizabeth A Hurt
    Nisonger Center, The Ohio State University, Columbus, OH 43210, USA
    Curr Psychiatry Rep 13:323-32. 2011
    ..Consequences of delayed proven treatments need consideration in the risk-benefit assessment of dietary/nutritional treatments...
  48. ncbi request reprint Treatment-related changes in objectively measured parenting behaviors in the multimodal treatment study of children with attention-deficit/hyperactivity disorder
    Karen C Wells
    Department of Psychiatry, Duke University Medical Center, Durham, NC, USA
    J Consult Clin Psychol 74:649-57. 2006
    ..The authors discuss the importance of changes in parenting behavior for families of children with ADHD and the need for reliable and objective measures in evaluating treatment outcome...
  49. ncbi request reprint Evidence, interpretation, and qualification from multiple reports of long-term outcomes in the Multimodal Treatment Study of children with ADHD (MTA): Part II: supporting details
    James Swanson
    UCI Child Development Center, University of California, Irvine, Irvine, CA 92612, USA
    J Atten Disord 12:15-43. 2008
    ..To review and provide details about the primary and secondary findings from the Multimodal Treatment study of ADHD (MTA) published during the past decade as three sets of articles...
  50. ncbi request reprint EFA supplementation in children with inattention, hyperactivity, and other disruptive behaviors
    Laura Stevens
    Department of Foods and Nutrition, Purdue University, West Lafayette, Indiana 47907, USA
    Lipids 38:1007-21. 2003
    ..54; n = 24, P < 0.05) as well as the ASQ for teachers (r = -0.51, n = 24, P < 0.05). Thus, the results of this pilot study suggest the need for further research with both n-3 FA and vitamin E in children with behavioral disorders...
  51. ncbi request reprint Evidence, interpretation, and qualification from multiple reports of long-term outcomes in the Multimodal Treatment study of Children With ADHD (MTA): part I: executive summary
    James Swanson
    UCI Child Development Center, University of California, Irvine, Irvine, CA 92612, USA
    J Atten Disord 12:4-14. 2008
    ..To review the primary and secondary findings from the Multimodal Treatment study of ADHD (MTA) published over the past decade as three sets of articles...
  52. ncbi request reprint A randomized, double-blind, placebo-controlled, parallel-group study of methylphenidate transdermal system in pediatric patients with attention-deficit/hyperactivity disorder
    Robert L Findling
    University Hospitals Case Medical Center, Cleveland, Ohio 44106, USA
    J Clin Psychiatry 69:149-59. 2008
    ..To evaluate the efficacy and safety of methylphenidate transdermal system compared with placebo, using osmotic-release oral system (OROS) methylphenidate as a reference therapy...
  53. ncbi request reprint Effects of short- and long-term risperidone treatment on prolactin levels in children with autism
    George M Anderson
    Child Study Center, Yale University School of Medicine, New Haven, Connecticut, USA
    Biol Psychiatry 61:545-50. 2007
    ..The effects of short- and long-term risperidone treatment on serum prolactin were assessed in children and adolescents with autism...
  54. ncbi request reprint Socioeconomic status as a moderator of ADHD treatment outcomes
    Ricardo Rieppi
    Department of Psychology, St Johns University, Jamaica, NY 11439, USA
    J Am Acad Child Adolesc Psychiatry 41:269-77. 2002
    ....
  55. ncbi request reprint Assessment of the integrity of study blindness in a pediatric clinical trial of risperidone
    Benedetto Vitiello
    Division of Services and Intervention Research, National Institute of Mental Health, Bethesda, MD 20892 9633, USA
    J Clin Psychopharmacol 25:565-9. 2005
    ..The blindness of clinical evaluators and parents was examined in a clinical trial of risperidone in autism...
  56. ncbi request reprint Cost-effectiveness of ADHD treatments: findings from the multimodal treatment study of children with ADHD
    Peter S Jensen
    Center for the Advancement of Children s Mental Health, Department of Child Psychiatry, New York State Psychiatric Institute, Columbia University, 1051 Riverside Dr, Suite 78, New York, NY 10032, USA
    Am J Psychiatry 162:1628-36. 2005
    ..To the authors' knowledge, this is the first study on the cost-effectiveness of the major forms of ADHD treatments used in NIMH's Multimodal Treatment Study of Children With ADHD (MTA Study)...
  57. ncbi request reprint Research knowledge among parents of children participating in a randomized clinical trial
    Benedetto Vitiello
    Child and Adolescent Treatment and Preventive Intervention Research Branch, National Institute of Mental Health, Bethesda, MD 20892 9633, USA
    J Am Acad Child Adolesc Psychiatry 44:145-9. 2005
    ..Parental permission is required for child research, but parents' understanding of research aims and procedures has not been well documented. Parental research knowledge was assessed during a clinical trial in autism...
  58. ncbi request reprint Peer-assessed outcomes in the multimodal treatment study of children with attention deficit hyperactivity disorder
    Betsy Hoza
    Department of Psychological Sciences, Purdue University, West Lafayette, IN 47907 2081, USA
    J Clin Child Adolesc Psychol 34:74-86. 2005
    ..Results indicated that children from all groups remained significantly impaired in their peer relationships...
  59. ncbi request reprint Weight and leptin changes among risperidone-treated youths with autism: 6-month prospective data
    Andres Martin
    Yale Child Study Center, Yale University, New Haven, CT 06520, USA
    Am J Psychiatry 161:1125-7. 2004
    ..The authors examined the developmental impact and temporal characteristics of risperidone-associated weight change...
  60. ncbi request reprint Response to methylphenidate in children with attention deficit hyperactivity disorder and manic symptoms in the multimodal treatment study of children with attention deficit hyperactivity disorder titration trial
    Cathryn A Galanter
    Columbia University New York State Psychiatric Institute, New York, New York 10032, USA
    J Child Adolesc Psychopharmacol 13:123-36. 2003
    ..Recent reports raise concern that children with attention deficit hyperactivity disorder (ADHD) and some manic symptoms may worsen with stimulant treatment. This study examines the response to methylphenidate in such children...
  61. ncbi request reprint Which treatment for whom for ADHD? Moderators of treatment response in the MTA
    Elizabeth B Owens
    Institute of Human Development, University of California, Berkeley 94720 1690, USA
    J Consult Clin Psychol 71:540-52. 2003
    ..No predictors or moderators emerged for behavioral and community comparison treatments. The authors discuss conceptual and clinical implications of research on treatment moderators...
  62. ncbi request reprint Risperidone in children with autism and serious behavioral problems
    James T McCracken
    University of California, Los Angeles, USA
    N Engl J Med 347:314-21. 2002
    ..However, data on the safety and efficacy of atypical antipsychotic agents in children are limited...
  63. ncbi request reprint Response to commentary on the multimodal treatment study of ADHD (MTA): mining the meaning of the MTA
    James M Swanson
    Department of Pediatrics, University of California, Irvine 92612, USA
    J Abnorm Child Psychol 30:327-32. 2002
    ..Finally, we invite others to use the large and rich data set that will soon be available in the public domain, to perform secondary analyses to mine the meaning of the MTA and to evaluate theories of ADHD and response to treatments...
  64. ncbi request reprint Emergency/Adjunct services and attrition prevention for randomized clinical trials in children: the MTA manual-based solution
    Howard Abikoff
    Child and Adolescent Psychiatry, NYU Child Study Center, NYU School of Medicine, NY 10016, USA
    J Am Acad Child Adolesc Psychiatry 41:498-504. 2002
    ..Although the manual-based guidelines are especially applicable to multisite RCTs, many of the procedures in the ASAP Manual can apply to any treatment study in children...
  65. ncbi request reprint Risperidone and adaptive behavior in children with autism
    Susan K Williams
    Yale University, New Haven, CT 06520 7900, USA
    J Am Acad Child Adolesc Psychiatry 45:431-9. 2006
    ..To evaluate the impact of risperidone on adaptive behavior in children with autistic disorder who have serious behavior problems and to examine different methods of scoring the Vineland Adaptive Behavior Scales to measure change...
  66. ncbi request reprint Assessing medication effects in the MTA study using neuropsychological outcomes
    Jeffery N Epstein
    Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27710, USA
    J Child Psychol Psychiatry 47:446-56. 2006
    ....
  67. ncbi request reprint Children's Yale-Brown Obsessive Compulsive Scale modified for pervasive developmental disorders
    Lawrence Scahill
    Yale Child Study Center, Yale University, New Haven, CT 06520, USA
    J Am Acad Child Adolesc Psychiatry 45:1114-23. 2006
    ..To examine the psychometric properties of the Children's Yale-Brown Obsessive Compulsive Scales (CYBOCS) modified for pervasive developmental disorders (PDDs)...
  68. ncbi request reprint Secondary evaluations of MTA 36-month outcomes: propensity score and growth mixture model analyses
    James M Swanson
    UCI Child Development Center, 19722 MacArthur Blvd, Irvine, CA 92612, USA
    J Am Acad Child Adolesc Psychiatry 46:1003-14. 2007
    ....
  69. ncbi request reprint Child and parent predictors of perceptions of parent--child relationship quality
    Alyson C Gerdes
    Marquette University, USA
    J Atten Disord 11:37-48. 2007
    ..The findings resolve a previous contradiction in the literature regarding the relationship between child depressive symptoms and parental perceptions of parent-child relationship quality...
  70. pmc Treatment for ADHD: is more complex treatment cost-effective for more complex cases?
    E Michael Foster
    Department of Maternal and Child Health, The University of North Carolina, School of Public Health, 407 C Rosenau Hall, CB 7445, Chapel Hill, NC 27599, USA
    Health Serv Res 42:165-82. 2007
    ..Data for the study were distilled from administrative data and from interviews with parents, including estimates of the child's functional impairment. These analyses focus on changes in functional impairment over 14 months...
  71. ncbi request reprint Effects of stimulant medication on growth rates across 3 years in the MTA follow-up
    James M Swanson
    UCI Child Development Center, 19722 MacArthur Blvd, Irvine, CA 92612, USA
    J Am Acad Child Adolesc Psychiatry 46:1015-27. 2007
    ..To evaluate the hypothesis of stimulant medication effect on physical growth in the follow-up phase of the Multimodal Treatment Study of Children With ADHD...
  72. ncbi request reprint Parent-rated anxiety symptoms in children with pervasive developmental disorders: frequency and association with core autism symptoms and cognitive functioning
    Denis G Sukhodolsky
    The Child Study Center, Yale University, 230 South Frontage Road, New Haven, CT 06520, USA
    J Abnorm Child Psychol 36:117-28. 2008
    ..Limited data are available on the prevalence of anxiety in these children. We examined frequency and correlates of parent-rated anxiety symptoms in a large sample of children with PDD...
  73. ncbi request reprint A prospective open trial of guanfacine in children with pervasive developmental disorders
    Lawrence Scahill
    Yale Child Study Center, P O Box 207900, New Haven, CT 06520, USA
    J Child Adolesc Psychopharmacol 16:589-98. 2006
    ..A common complaint for children with pervasive developmental disorder (PDD) is hyperactivity. The purpose of this pilot study was to gather preliminary information on the efficacy of guanfacine in children with PDD and hyperactivity...
  74. ncbi request reprint 3-year follow-up of the NIMH MTA study
    Peter S Jensen
    Center for the Advancement of Children s Mental Health, Unit 78, Columbia University NYSPI, 1051 Riverside Drive, New York, NY 10027, USA
    J Am Acad Child Adolesc Psychiatry 46:989-1002. 2007
    ..This report examines 36-month outcomes, 2 years after treatment by the study ended...
  75. ncbi request reprint Maternal depressive symptomatology and parenting behavior: exploration of possible mediators
    Alyson C Gerdes
    Psychology Department, Marquette University, P O Box 1881, Milwaukee, WI 53201 1881, USA
    J Abnorm Child Psychol 35:705-14. 2007
    ....
  76. pmc The transition to middle school is associated with changes in the developmental trajectory of ADHD symptomatology in young adolescents with ADHD
    Joshua M Langberg
    Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229 3039, USA
    J Clin Child Adolesc Psychol 37:651-63. 2008
    ..These results support the assertion that the environmental changes associated with transitioning to middle school coincide with a transient reversal in ADHD symptom decline among children with ADHD...
  77. ncbi request reprint Hallucinations associated with initiation of guanfacine
    Craig D Boreman
    J Am Acad Child Adolesc Psychiatry 42:1387. 2003
  78. ncbi request reprint Self-perceptions of competence in children with ADHD and comparison children
    Betsy Hoza
    Department of Psychological Sciences, Purdue University, West Lafayette, IN 47907 2081, USA
    J Consult Clin Psychol 72:382-91. 2004
    ..Examination by comorbidity subgroups revealed that children with ADHD inflated their self-perceptions the most in domains of greatest deficit. Gender effects also are reported...
  79. ncbi request reprint The services for children and adolescents-parent interview: development and performance characteristics
    Peter S Jensen
    Center for the Advancement of Children s Mental Health of Columbia University, New York, 10032, USA
    J Am Acad Child Adolesc Psychiatry 43:1334-44. 2004
    ....
  80. ncbi request reprint Reliability of the services for children and adolescents-parent interview
    Kimberly Eaton Hoagwood
    Bureau of Child and Adolescent Services Research, New York State Office of Mental Health, and Columbia University, New York, NY 10032, USA
    J Am Acad Child Adolesc Psychiatry 43:1345-54. 2004
    ....
  81. ncbi request reprint What aspects of peer relationships are impaired in children with attention-deficit/hyperactivity disorder?
    Betsy Hoza
    Department of Psychological Sciences, Purdue University, West Lafayette, IN 47907 2081, USA
    J Consult Clin Psychol 73:411-23. 2005
    ....
  82. ncbi request reprint Neurochemical correlates of autistic disorder: a review of the literature
    Kristen S L Lam
    Neurodevelopmental Disorders Research Center, University of North Carolina at Chapel Hill, USA
    Res Dev Disabil 27:254-89. 2006
    ..In addition, research in neurochemistry must continue to work in concert with other subspecialties to form a more comprehensive and theory-based approach to the neurobiological correlates of autistic disorder...
  83. pmc Developmental disabilities modification of the Children's Global Assessment Scale
    Ann Wagner
    National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland, USA
    Biol Psychiatry 61:504-11. 2007
    ..To measure global functioning in treatment studies, the Children's Global Assessment Scale was modified and psychometric properties of the revised version (DD-CGAS) were assessed in children with PDD...
  84. ncbi request reprint Diagnosing and managing complicated ADHD
    Robert L Findling
    Department of Psychiatry and Pediatrics, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, Ohio, USA
    J Clin Psychiatry 68:1963-70. 2007