CHARLES ALLIS

Summary

Affiliation: The Rockefeller University
Country: USA

Publications

  1. pmc Linking the epigenetic 'language' of covalent histone modifications to cancer
    S B Hake
    Laboratory of Chromatin Biology, The Rockefeller University, Box 78, 1230 York Avenue, New York, NY 10021, USA
    Br J Cancer 90:761-9. 2004
  2. pmc WSTF regulates the H2A.X DNA damage response via a novel tyrosine kinase activity
    Andrew Xiao
    Laboratory of Chromatin Biology, The Rockefeller University, New York, New York 10065, USA
    Nature 457:57-62. 2009
  3. pmc Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger
    Gang G Wang
    Laboratory of Chromatin Biology and Epigenetics, The Rockefeller University, New York, New York 10065, USA
    Nature 459:847-51. 2009
  4. pmc Histone H3 variants and their potential role in indexing mammalian genomes: the "H3 barcode hypothesis"
    Sandra B Hake
    Laboratory of Chromatin Biology, The Rockefeller University, Box 78, 1230 York Avenue, New York, NY 10021, USA
    Proc Natl Acad Sci U S A 103:6428-35. 2006

Research Grants

Collaborators

Detail Information

Publications4

  1. pmc Linking the epigenetic 'language' of covalent histone modifications to cancer
    S B Hake
    Laboratory of Chromatin Biology, The Rockefeller University, Box 78, 1230 York Avenue, New York, NY 10021, USA
    Br J Cancer 90:761-9. 2004
    ..This review focuses on how aberrant covalent histone modifications may contribute to the development of a variety of human cancers, and discusses the recent findings with regard to potential therapies...
  2. pmc WSTF regulates the H2A.X DNA damage response via a novel tyrosine kinase activity
    Andrew Xiao
    Laboratory of Chromatin Biology, The Rockefeller University, New York, New York 10065, USA
    Nature 457:57-62. 2009
    ..Our work demonstrates a new mechanism that regulates the DNA damage response and expands our knowledge of domains that contain intrinsic tyrosine kinase activity...
  3. pmc Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger
    Gang G Wang
    Laboratory of Chromatin Biology and Epigenetics, The Rockefeller University, New York, New York 10065, USA
    Nature 459:847-51. 2009
    ....
  4. pmc Histone H3 variants and their potential role in indexing mammalian genomes: the "H3 barcode hypothesis"
    Sandra B Hake
    Laboratory of Chromatin Biology, The Rockefeller University, Box 78, 1230 York Avenue, New York, NY 10021, USA
    Proc Natl Acad Sci U S A 103:6428-35. 2006
    ..Although we restrict our comments to H3 variants in mammals, we expect that the more general concepts presented here will apply to other histone variant families in organisms that employ them...

Research Grants25

  1. Enzymology and Function(s) of Histone Phosphorylation
    CHARLES ALLIS; Fiscal Year: 2006
    ..X, with oncogenesis provides strong support for an emerging view that covalent modification of histones plays a vital role in the regulation of chromatin dynamics with far-reaching implications for human biology and disease. ..
  2. Chromatin Remodeling and Programmed DNA Elimination
    CHARLES ALLIS; Fiscal Year: 2006
    ..abstract_text> ..
  3. Enzymology and Function(s) of Histone Phosphorylation
    CHARLES ALLIS; Fiscal Year: 2007
    ..X, with oncogenesis provides strong support for an emerging view that covalent modification of histones plays a vital role in the regulation of chromatin dynamics with far-reaching implications for human biology and disease. ..
  4. Deciphering the Histone Code
    CHARLES ALLIS; Fiscal Year: 2007
    ..Understanding these mechanisms in normal development is essential if we are to understand cases of abnormal development, some congenital diseases and certain pathological situations such as neoplastic transformation. ..
  5. Chromatin Remodeling and Programmed DNA Elimination
    CHARLES ALLIS; Fiscal Year: 2007
    ..abstract_text> ..
  6. Enzymology and Function(s) of Histone Phosphorylation
    CHARLES ALLIS; Fiscal Year: 2009
    ..abstract_text> ..
  7. Enzymology and Function(s) of Histone Phosphorylation
    CHARLES DAVID ALLIS; Fiscal Year: 2010
    ..Knowing how to control which genes to turn on or off, using therapy, could reduce the risk of certain diseases. The implications of this research for human biology and human health are far-reaching. ..
  8. Chromatin Remodeling and Programmed DNA Elimination
    CHARLES ALLIS; Fiscal Year: 2005
    ..abstract_text> ..
  9. Enzymology and Function(s) of Histone Phosphorylation
    CHARLES ALLIS; Fiscal Year: 2005
    ..abstract_text> ..
  10. Chromatin Remodeling and Programmed DNA Elimination
    CHARLES ALLIS; Fiscal Year: 2004
    ..Whether any of the 'rules' that emerge from these studies will also apply to heterochromatin-induced gene inactivation in other organisms is not known, but remains an exciting possibility. ..
  11. CHROMOSOMAL PROTEIN FUNCTION AND PHOSPHORYLATION
    CHARLES ALLIS; Fiscal Year: 1999
    ..Understanding these mechanisms in normal cells is essential if the investigator is to understand abnormal development and tumorigenesis. ..
  12. CHROMOSOMAL PROTEIN FUNCTION AND PHOSPHORYLATION
    CHARLES ALLIS; Fiscal Year: 2000
    ..Understanding these mechanisms in normal cells is essential if the investigator is to understand abnormal development and tumorigenesis. ..
  13. CHROMOSOMAL PROTEIN FUNCTION AND PHOSPHORYLATION
    CHARLES ALLIS; Fiscal Year: 2001
    ..Understanding these mechanisms in normal cells is essential if the investigator is to understand abnormal development and tumorigenesis. ..
  14. Chromatin Remodeling and Programmed DNA Elimination
    CHARLES ALLIS; Fiscal Year: 2001
    ..Whether any of the 'rules' that emerge from these studies will also apply to heterochromatin-induced gene inactivation in other organisms is not known, but remains an exciting possibility. ..
  15. Enzymology and Function(s) of Histone Phosphorylation
    CHARLES ALLIS; Fiscal Year: 2002
    ..abstract_text> ..
  16. Chromatin Remodeling and Programmed DNA Elimination
    CHARLES ALLIS; Fiscal Year: 2002
    ..Whether any of the 'rules' that emerge from these studies will also apply to heterochromatin-induced gene inactivation in other organisms is not known, but remains an exciting possibility. ..
  17. Enzymology and Function(s) of Histone Phosphorylation
    CHARLES ALLIS; Fiscal Year: 2002
    ..abstract_text> ..
  18. Enzymology and Function(s) of Histone Phosphorylation
    CHARLES ALLIS; Fiscal Year: 2003
    ..abstract_text> ..
  19. Chromatin Remodeling and Programmed DNA Elimination
    CHARLES ALLIS; Fiscal Year: 2003
    ..Whether any of the 'rules' that emerge from these studies will also apply to heterochromatin-induced gene inactivation in other organisms is not known, but remains an exciting possibility. ..
  20. Enzymology and Function(s) of Histone Phosphorylation
    CHARLES ALLIS; Fiscal Year: 2004
    ..abstract_text> ..
  21. Enzymology and Function(s) of Histone Phosphorylation
    CHARLES DAVID ALLIS; Fiscal Year: 2011
    ..Knowing how to control which genes to turn on or off, using therapy, could reduce the risk of certain diseases. The implications of this research for human biology and human health are far-reaching. ..