N S Abend

Summary

Affiliation: The Children's Hospital of Philadelphia
Country: USA

Publications

  1. doi request reprint Electrographic seizures and status epilepticus in critically ill children and neonates with encephalopathy
    Nicholas S Abend
    Departments of Neurology and Pediatrics, The Children s Hospital of Philadelphia and Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA Electronic address
    Lancet Neurol 12:1170-9. 2013
  2. pmc Electrographic seizures in pediatric ICU patients: cohort study of risk factors and mortality
    Nicholas S Abend
    Department of Neurology, The Children s Hospital of Philadelphia, Philadelphia, PA, USA
    Neurology 81:383-91. 2013
  3. pmc Treatment of electrographic seizures and status epilepticus in critically ill children: a single center experience
    Nicholas S Abend
    Division of Neurology, The Perelman School of Medicine at the University of Pennsylvania, USA
    Seizure 22:467-71. 2013
  4. pmc A review of long-term EEG monitoring in critically ill children with hypoxic-ischemic encephalopathy, congenital heart disease, ECMO, and stroke
    Nicholas S Abend
    Division of Neurology, The Children s Hospital of Philadelphia and Department of Neurology, The University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    J Clin Neurophysiol 30:134-42. 2013
  5. pmc Electroencephalographic monitoring in the pediatric intensive care unit
    Nicholas S Abend
    Division of Neurology, The Children s Hospital of Philadelphia, The Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA
    Curr Neurol Neurosci Rep 13:330. 2013
  6. pmc Neonatal seizures and status epilepticus
    Nicholas S Abend
    Division of Neurology, The Children s Hospital of Philadelphia, the Departments of Neurology and Pediatrics, The University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    J Clin Neurophysiol 29:441-8. 2012
  7. pmc Outcome prediction by motor and pupillary responses in children treated with therapeutic hypothermia after cardiac arrest
    Nicholas S Abend
    Division of Neurology, The Children s Hospital of Philadelphia, The University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Pediatr Crit Care Med 13:32-8. 2012
  8. pmc Impact of continuous EEG monitoring on clinical management in critically ill children
    Nicholas S Abend
    Division of Neurology, The Children s Hospital of Philadelphia, 34th Street and Civic Center Blvd, Philadelphia, PA 19104, USA
    Neurocrit Care 15:70-5. 2011
  9. doi request reprint Medical treatment of pediatric status epilepticus
    Nicholas S Abend
    Department of Neurology, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Semin Pediatr Neurol 17:169-75. 2010
  10. pmc Interobserver reproducibility of electroencephalogram interpretation in critically ill children
    Nicholas S Abend
    Division of Neurology, The Children s Hospital of Philadelphia, Pennsylvania 19104, USA
    J Clin Neurophysiol 28:15-9. 2011

Detail Information

Publications32

  1. doi request reprint Electrographic seizures and status epilepticus in critically ill children and neonates with encephalopathy
    Nicholas S Abend
    Departments of Neurology and Pediatrics, The Children s Hospital of Philadelphia and Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA Electronic address
    Lancet Neurol 12:1170-9. 2013
    ..Further research is needed to determine whether identification and management of electrographic seizures reduces secondary brain injury and improves outcome in critically ill children and neonates. ..
  2. pmc Electrographic seizures in pediatric ICU patients: cohort study of risk factors and mortality
    Nicholas S Abend
    Department of Neurology, The Children s Hospital of Philadelphia, Philadelphia, PA, USA
    Neurology 81:383-91. 2013
    ....
  3. pmc Treatment of electrographic seizures and status epilepticus in critically ill children: a single center experience
    Nicholas S Abend
    Division of Neurology, The Perelman School of Medicine at the University of Pennsylvania, USA
    Seizure 22:467-71. 2013
    ..Survey data indicate most physicians treat ES and ESE with antiepileptic drugs (AEDs), but few data are available regarding AED usage patterns. We aimed to describe AED usage for ES and ESE in critically ill children...
  4. pmc A review of long-term EEG monitoring in critically ill children with hypoxic-ischemic encephalopathy, congenital heart disease, ECMO, and stroke
    Nicholas S Abend
    Division of Neurology, The Children s Hospital of Philadelphia and Department of Neurology, The University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    J Clin Neurophysiol 30:134-42. 2013
    ..This review summarizes the available data regarding continuous EEG monitoring in critically ill children with special attention to hypoxic ischemic encephalopathy, congenital heart disease, stroke, and children undergoing ECMO...
  5. pmc Electroencephalographic monitoring in the pediatric intensive care unit
    Nicholas S Abend
    Division of Neurology, The Children s Hospital of Philadelphia, The Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA
    Curr Neurol Neurosci Rep 13:330. 2013
    ....
  6. pmc Neonatal seizures and status epilepticus
    Nicholas S Abend
    Division of Neurology, The Children s Hospital of Philadelphia, the Departments of Neurology and Pediatrics, The University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    J Clin Neurophysiol 29:441-8. 2012
    ....
  7. pmc Outcome prediction by motor and pupillary responses in children treated with therapeutic hypothermia after cardiac arrest
    Nicholas S Abend
    Division of Neurology, The Children s Hospital of Philadelphia, The University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Pediatr Crit Care Med 13:32-8. 2012
    ..We aimed to determine the prognostic value of motor and pupillary responses in children treated with therapeutic hypothermia after cardiac arrest...
  8. pmc Impact of continuous EEG monitoring on clinical management in critically ill children
    Nicholas S Abend
    Division of Neurology, The Children s Hospital of Philadelphia, 34th Street and Civic Center Blvd, Philadelphia, PA 19104, USA
    Neurocrit Care 15:70-5. 2011
    ..We aimed to determine prospectively the impact of cEEG on clinical management in critically ill children...
  9. doi request reprint Medical treatment of pediatric status epilepticus
    Nicholas S Abend
    Department of Neurology, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Semin Pediatr Neurol 17:169-75. 2010
    ....
  10. pmc Interobserver reproducibility of electroencephalogram interpretation in critically ill children
    Nicholas S Abend
    Division of Neurology, The Children s Hospital of Philadelphia, Pennsylvania 19104, USA
    J Clin Neurophysiol 28:15-9. 2011
    ..Because even seizure identification had only moderate agreement, studies of nonconvulsive seizures in critically ill patients must be conducted and interpreted cautiously...
  11. pmc Levetiracetam for treatment of neonatal seizures
    Nicholas S Abend
    Division of Neurology, The Children s Hospital of Philadelphia, Philadelphia, PA, USA
    J Child Neurol 26:465-70. 2011
    ..Further study is warranted to determine optimal levetiracetam dosing in neonates and to compare efficacy with other antiseizure medications...
  12. pmc Nonconvulsive seizures are common in critically ill children
    N S Abend
    Division of Neurology, The Children s Hospital of Philadelphia, 34th Street and Civic Center Blvd, Philadelphia, PA 19104, USA
    Neurology 76:1071-7. 2011
    ..We aimed to prospectively determine the incidence and risk factors of nonconvulsive seizures in critically ill children using predetermined EEG monitoring indications and EEG interpretation terminology...
  13. pmc Seizures as a presenting symptom of acute arterial ischemic stroke in childhood
    Nicholas S Abend
    Department of Neurology, The Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    J Pediatr 159:479-83. 2011
    ..To define the incidence of seizures as a presenting symptom of acute arterial ischemic stroke (AIS) in children and to determine whether younger age, infarct location, or AIS etiology were risk factors for seizure at AIS presentation...
  14. pmc Use of EEG monitoring and management of non-convulsive seizures in critically ill patients: a survey of neurologists
    Nicholas S Abend
    Division of Neurology, The Children s Hospital of Philadelphia, 34th Street and Civic Center Blvd, Philadelphia, PA 19104, USA
    Neurocrit Care 12:382-9. 2010
    ..The indications for cEEG, as well as when and how to treat NCS, remain unclear. We aimed to describe the current practice of cEEG in critically ill patients to define areas of uncertainty that could aid in designing future research...
  15. pmc Electroencephalographic monitoring during hypothermia after pediatric cardiac arrest
    N S Abend
    Division of Neurology, The Children s Hospital of Philadelphia, 34th Street and Civic Center Boulevard, Philadelphia, PA 19104, USA
    Neurology 72:1931-40. 2009
    ....
  16. ncbi request reprint Lupus anticoagulant and thrombosis following Henoch-Schonlein purpura
    Nicholas S Abend
    Division of Neurology, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
    Pediatr Neurol 36:345-7. 2007
    ..Children who develop Henoch-Schonlein purpura with neurologic features including headache should be evaluated for sinovenous thrombosis and a hypercoagulable state...
  17. ncbi request reprint Nonconvulsive status epilepticus in a pediatric intensive care unit
    Nicholas S Abend
    Division of Neurology, Children s Hospital of Philadelphia 19104, USA
    Pediatr Neurol 37:165-70. 2007
    ..These findings suggest that a high level of suspicion for nonconvulsive status epilepticus must be maintained, and long-term electroencephalogram monitoring may be indicated in a large number of patients...
  18. ncbi request reprint Status epilepticus secondary to hypertensive encephalopathy as the presenting manifestation of Guillain-Barré syndrome
    Nicholas S Abend
    Division of Neurology, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    Pediatr Emerg Care 23:659-61. 2007
    ..Guillain-Barré syndrome may result in hypertensive encephalopathy that can manifest as status epilepticus before the onset of motor symptoms...
  19. ncbi request reprint Neonatal seizure detection using multichannel display of envelope trend
    Nicholas S Abend
    Division of Neurology, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
    Epilepsia 49:349-52. 2008
    ..Less experienced users were less accurate. Trending may be a useful tool for seizure detection in some neonates...
  20. doi request reprint Intravenous levetiracetam terminates refractory focal status epilepticus
    Nicholas S Abend
    Division of Neurology, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    Neurocrit Care 10:83-6. 2009
    ....
  21. doi request reprint Subcutaneous sumatriptan in an adolescent with acute posttraumatic headache
    Nicholas S Abend
    Division of Neurology, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    J Child Neurol 23:438-40. 2008
    ..We describe an adolescent with acute posttraumatic headache that did not respond to several initial medications but had rapid and sustained improvement in headache and associated migrainous features with subcutaneous sumatriptan...
  22. doi request reprint Predicting outcome in children with hypoxic ischemic encephalopathy
    Nicholas S Abend
    Division of Neurology, The Children s Hospital of Philadelphia, Department of Neurology, The University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Pediatr Crit Care Med 9:32-9. 2008
    ..These include historical features of the event; physical exam signs; neurophysiologic studies, such as electroencephalogram and evoked potentials; and neuroimaging...
  23. doi request reprint Treatment of refractory status epilepticus: literature review and a proposed protocol
    Nicholas S Abend
    Division of Neurology, Children s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
    Pediatr Neurol 38:377-90. 2008
    ..Additional management strategies that could be employed in tertiary-care settings, such as coma induction guided by continuous electroencephalogram monitoring and surgical options, are also discussed...
  24. doi request reprint Anticonvulsant medications in the pediatric emergency room and intensive care unit
    Nicholas S Abend
    Division of Neurology, Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    Pediatr Emerg Care 24:705-18; quiz 719-21. 2008
    ..Treatment issues specific to complex medical patients, including patients with brain tumors, renal dysfunction, hepatic dysfunction, transplant, congenital heart disease, and anticoagulation, are also discussed...
  25. pmc Intravenous levetiracetam in critically ill children with status epilepticus or acute repetitive seizures
    Nicholas S Abend
    Division of Neurology, The Children s Hospital of Philadelphia, Philadelphia, PA, USA
    Pediatr Crit Care Med 10:505-10. 2009
    ..We aim to investigate the safety, an appropriate dosing, and efficacy of IV LEV in critically ill children...
  26. ncbi request reprint Convulsive and nonconvulsive status epilepticus in children
    Nicholas S Abend
    Eric Marsh, MD, PhD Division of Neurology, Children s Hospital of Philadelphia, 34th Street and Civic Center Boulevard, Philadelphia, PA 19104, USA
    Curr Treat Options Neurol 11:262-72. 2009
    ..This review evaluates treatment protocols for acute SE, prolonged SE, and nonconvulsive SE, including some management strategies that use newer anticonvulsants...
  27. doi request reprint Cerebral sinus venous thrombosis complicated by cerebellar hemorrhage in a child with acute promyelocytic leukemia
    Lauren A Beslow
    Division of Neurology, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
    J Child Neurol 24:110-4. 2009
    ..This case suggests that in a controlled setting, anticoagulation may be safe in selected patients with cerebellar hemorrhage...
  28. ncbi request reprint Hemosiderin-laden macrophages in the cerebrospinal fluid of a neonate after traumatic lumbar puncture
    Courtney J Wusthoff
    Department of Pediatrics, Division of Neurology, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    Pediatr Infect Dis J 27:83-4. 2008
    ..This suggests that although macrophages may indicate pathology, they can also accumulate after traumatic lumbar puncture...
  29. pmc Anti-NMDA receptor encephalitis presenting with focal non-convulsive status epilepticus in a child
    E M Goldberg
    Department of Neurology, The Hospital of the University of Pennsylvania, Philadelphia, PA, USA
    Neuropediatrics 42:188-90. 2011
    ..Cerebrospinal fluid (CSF) was positive for antibodies directed against the N-methyl-d-aspartate receptor (NMDAR). This case is the first report of anti-NMDAR encephalitis presenting with focal non-convulsive status epilepticus (NCSE)...
  30. ncbi request reprint Hypodense middle cerebral artery with fat embolus
    Nicholas S Abend
    Division of Neurology, The Children s Hospital of Philadelphia, and Department of Neurology, Hospital of the University of Philadelphia, PA 19104, USA
    Neurocrit Care 6:147-8. 2007
    ..We briefly review the phenomenon of fat embolism and discuss the salient radiographic (CT) finding in this case--a "hypodense artery sign."..
  31. doi request reprint Secondary headaches in children and adolescents
    Nicholas S Abend
    Division of Neurology, Children s Hospital of Philadelphia University, Philadelphia, PA, USA
    Semin Pediatr Neurol 17:123-33. 2010
    ..This will also guide clinical decision making regarding the need for further diagnostic testing, including neuroimaging, electrophysiological testing, or specific laboratory testing...
  32. doi request reprint Vein of galen aneurysmal malformation with deep venous communication and subarachnoid hemorrhage
    Nicholas S Abend
    Division of Neurology, The Children s Hospital of Philadelphia, Department of Neurology, University of Pennsylvania Medical Center, Philadelphia, PA 19104, USA
    J Child Neurol 23:441-6. 2008
    ..Such a communication implies that endovascular or surgical obliteration of the venous side of a vein of Galen aneurysmal malformation may impair normal venous drainage, potentially resulting in a venous infract or hemorrhage...