Stephen T Abedon

Summary

Affiliation: The Ohio State University
Country: USA

Publications

  1. ncbi Spatial vulnerability: bacterial arrangements, microcolonies, and biofilms as responses to low rather than high phage densities
    Stephen T Abedon
    Department of Microbiology, The Ohio State University, 1680 University Dr, Mansfield, OH 44906, USA
    Viruses 4:663-87. 2012
  2. ncbi Phage therapy pharmacology
    Stephen T Abedon
    Department of Microbiology, The Ohio State University, 1680 University Dr, Mansfield, OH 44906, USA
    Curr Pharm Biotechnol 11:28-47. 2010
  3. ncbi Kinetics of phage-mediated biocontrol of bacteria
    Stephen T Abedon
    Department of Microbiology, The Ohio State University, Mansfield, Ohio 44906, USA
    Foodborne Pathog Dis 6:807-15. 2009
  4. ncbi Bacteriophage T4 resistance to lysis-inhibition collapse
    S T Abedon
    Department of Microbiology, Ohio State University, Mansfield 44906, USA
    Genet Res 74:1-11. 1999
  5. ncbi Optimizing bacteriophage plaque fecundity
    Stephen T Abedon
    Department of Microbiology, The Ohio State University, Mansfield, OH 44906, USA
    J Theor Biol 249:582-92. 2007
  6. ncbi Bacteriophage evolution given spatial constraint
    Stephen T Abedon
    Department of Microbiology, The Ohio State University, Mansfield, OH 44906, USA
    J Theor Biol 248:111-9. 2007
  7. ncbi Experimental examination of bacteriophage latent-period evolution as a response to bacterial availability
    Stephen T Abedon
    Department of Microbiology, Ohio State University, Mansfield, Ohio, USA
    Appl Environ Microbiol 69:7499-506. 2003
  8. ncbi Bacteriophage latent-period evolution as a response to resource availability
    S T Abedon
    Department of Microbiology, Ohio State University, Mansfield, Ohio 44906, USA
    Appl Environ Microbiol 67:4233-41. 2001
  9. ncbi Practical methods for determining phage growth parameters
    Paul Hyman
    MedCentral College of Nursing, Mansfield, OH, USA
    Methods Mol Biol 501:175-202. 2009
  10. ncbi Bacteriophage host range and bacterial resistance
    Paul Hyman
    MedCentral College of Nursing, Mansfield, Ohio, USA
    Adv Appl Microbiol 70:217-48. 2010

Detail Information

Publications14

  1. ncbi Spatial vulnerability: bacterial arrangements, microcolonies, and biofilms as responses to low rather than high phage densities
    Stephen T Abedon
    Department of Microbiology, The Ohio State University, 1680 University Dr, Mansfield, OH 44906, USA
    Viruses 4:663-87. 2012
    ..I consider these ideas of bacterial 'spatial vulnerability' in part within a phage therapy context...
  2. ncbi Phage therapy pharmacology
    Stephen T Abedon
    Department of Microbiology, The Ohio State University, 1680 University Dr, Mansfield, OH 44906, USA
    Curr Pharm Biotechnol 11:28-47. 2010
    ....
  3. ncbi Kinetics of phage-mediated biocontrol of bacteria
    Stephen T Abedon
    Department of Microbiology, The Ohio State University, Mansfield, Ohio 44906, USA
    Foodborne Pathog Dis 6:807-15. 2009
    ..I conclude suggesting that phage therapy ultimately may be rationally guided by theoretical considerations of the impact of phage properties on rates of phage population growth...
  4. ncbi Bacteriophage T4 resistance to lysis-inhibition collapse
    S T Abedon
    Department of Microbiology, Ohio State University, Mansfield 44906, USA
    Genet Res 74:1-11. 1999
    ..From these data it is inferred that wild-type T4-infected cells display resistance to lysis-inhibition collapse by a mechanism resembling resistance to lysis from without...
  5. ncbi Optimizing bacteriophage plaque fecundity
    Stephen T Abedon
    Department of Microbiology, The Ohio State University, Mansfield, OH 44906, USA
    J Theor Biol 249:582-92. 2007
    ....
  6. ncbi Bacteriophage evolution given spatial constraint
    Stephen T Abedon
    Department of Microbiology, The Ohio State University, Mansfield, OH 44906, USA
    J Theor Biol 248:111-9. 2007
    ..Overall, we provide a snapshot of how phage populations may respond evolutionarily to selection for more-rapid propagation during spatially constrained growth...
  7. ncbi Experimental examination of bacteriophage latent-period evolution as a response to bacterial availability
    Stephen T Abedon
    Department of Microbiology, Ohio State University, Mansfield, Ohio, USA
    Appl Environ Microbiol 69:7499-506. 2003
    ..From these observations we suggest that phage displaying very short latent periods may be viewed as specialists for propagation when bacteria within cultures are highly prevalent and transmission between cultures is easily accomplished...
  8. ncbi Bacteriophage latent-period evolution as a response to resource availability
    S T Abedon
    Department of Microbiology, Ohio State University, Mansfield, Ohio 44906, USA
    Appl Environ Microbiol 67:4233-41. 2001
    ..By taking care to differentiate latent-period phenotypic plasticity from latent-period evolution, we argue that the impact of host quality on phage latent-period evolution may be relatively small...
  9. ncbi Practical methods for determining phage growth parameters
    Paul Hyman
    MedCentral College of Nursing, Mansfield, OH, USA
    Methods Mol Biol 501:175-202. 2009
    ..In this chapter we present protocols for determining phage growth parameters, particularly phage rate of adsorption, latent period, eclipse period, and burst size...
  10. ncbi Bacteriophage host range and bacterial resistance
    Paul Hyman
    MedCentral College of Nursing, Mansfield, Ohio, USA
    Adv Appl Microbiol 70:217-48. 2010
    ..Contrasting especially bacteria mutation to adsorption resistance, these latter mechanisms likely are an underappreciated avenue of bacterial resistance to phage attack...
  11. ncbi Human Escherichia coli O157:H7 genetic marker in isolates of bovine origin
    Jeffrey T Lejeune
    Ohio State University, Wooster, Ohio 44691, USA
    Emerg Infect Dis 10:1482-5. 2004
    ..5% of bovine isolates. Shiga toxin production was higher in Q933-positive isolates than Q933-negative isolates. This genetic marker may provide a useful molecular tool for epidemiologic studies...
  12. ncbi Bacteriophage plaques: theory and analysis
    Stephen T Abedon
    Department of Microbiology, The Ohio State University, Mansfield, OH, USA
    Methods Mol Biol 501:161-74. 2009
    ..We also will consider problems with inferring phage broth growth fitness as a function of plaque characteristics (Note 2)...
  13. ncbi Phage evolution and ecology
    Stephen T Abedon
    Department of Microbiology, College of Biological Sciences, The Ohio State University, Mansfield, Ohio 44906, USA
    Adv Appl Microbiol 67:1-45. 2009
    ....
  14. ncbi Host density impacts relative fitness of bacteriophage Phi6 genotypes in structured habitats
    John J Dennehy
    Department of Ecology and Evolutionary Biology, Yale University, New Haven, Connecticut 06520 8106, USA
    Evolution 61:2516-27. 2007
    ..We discuss the relevance of our findings for selection occurring in natural phage populations and for the general evolutionary epidemiology of infectious parasites...