Marilyn J Aardema

Summary

Affiliation: The Procter and Gamble Company
Country: USA

Publications

  1. ncbi Toxicology and genetic toxicology in the new era of "toxicogenomics": impact of "-omics" technologies
    Marilyn J Aardema
    Miami Valley Laboratories, The Procter and Gamble Co, P O Box 538707, Cincinnati, OH 45253, USA
    Mutat Res 499:13-25. 2002
  2. ncbi Identification of a gene expression profile that discriminates indirect-acting genotoxins from direct-acting genotoxins
    Ting Hu
    The Procter and Gamble Company, Miami Valley Laboratories, P O Box 538707 09, Cincinnati, OH 45253 8707, USA
    Mutat Res 549:5-27. 2004
  3. doi Intralaboratory and interlaboratory evaluation of the EpiDerm 3D human reconstructed skin micronucleus (RSMN) assay
    Ting Hu
    The Procter and Gamble Co, P O Box 538707, Cincinnati, OH 45253, United States
    Mutat Res 673:100-8. 2009
  4. ncbi An evaluation of the genotoxicity of the antitussive drug Dextromethorphan
    Marilyn J Aardema
    The Procter and Gamble Co, Miami Valley Innovation Center, P O Box 538707, Cincinnati, OH 45253, USA
    Regul Toxicol Pharmacol 50:285-93. 2008
  5. doi International prevalidation studies of the EpiDerm 3D human reconstructed skin micronucleus (RSMN) assay: transferability and reproducibility
    Marilyn J Aardema
    Procter and Gamble, Miami Valley Laboratories, 11810 East Miami River Road, Cincinnati, OH 45253, USA
    Mutat Res 701:123-31. 2010
  6. doi Evaluation of the genotoxicity of the imidazole antifungal climbazole: comparison to published results for other azole compounds
    ALEX A PEREZ-RIVERA
    The Procter and Gamble Company, Sharon Woods Innovation Center, Cincinnati, OH 45241, USA
    Mutat Res 672:27-39. 2009
  7. ncbi SFTG international collaborative study on in vitro micronucleus test III. Using CHO cells
    Marilyn J Aardema
    Procter and Gamble Co, Miami Valley Laboratories, Cincinnati, OH 45253 8707, USA
    Mutat Res 607:61-87. 2006
  8. doi A review of biomonitoring studies measuring genotoxicity in humans exposed to hair dyes
    R Julian Preston
    The Procter and Gamble Co, Cincinnati, OH 45241, USA
    Mutagenesis 25:17-23. 2010
  9. ncbi Development of a method for assessing micronucleus induction in a 3D human skin model (EpiDerm)
    Rodger D Curren
    Institute for In Vitro Sciences Inc, 21 Firstfield Road, Suite 220, Gaithersburg, MD 20878, USA
    Mutat Res 607:192-204. 2006
  10. ncbi Laboratory variability does not preclude identification of biological functions impacted by hydroxyurea
    Arne Muller
    Drug Safety Evaluation, Sanofi Aventis, Vitry sur Seine, France
    Environ Mol Mutagen 46:221-35. 2005

Collaborators

Detail Information

Publications11

  1. ncbi Toxicology and genetic toxicology in the new era of "toxicogenomics": impact of "-omics" technologies
    Marilyn J Aardema
    Miami Valley Laboratories, The Procter and Gamble Co, P O Box 538707, Cincinnati, OH 45253, USA
    Mutat Res 499:13-25. 2002
    ..Instead, a new integrated approach will likely emerge that involves a comprehensive understanding of genetic control of cellular functions, and of cellular responses to alterations in normal molecular structure and function...
  2. ncbi Identification of a gene expression profile that discriminates indirect-acting genotoxins from direct-acting genotoxins
    Ting Hu
    The Procter and Gamble Company, Miami Valley Laboratories, P O Box 538707 09, Cincinnati, OH 45253 8707, USA
    Mutat Res 549:5-27. 2004
    ....
  3. doi Intralaboratory and interlaboratory evaluation of the EpiDerm 3D human reconstructed skin micronucleus (RSMN) assay
    Ting Hu
    The Procter and Gamble Co, P O Box 538707, Cincinnati, OH 45253, United States
    Mutat Res 673:100-8. 2009
    ..These results indicate the RSMN assay using the EpiDerm 3D human skin model is a promising new in vitro genotoxicity assay that allows evaluation of chromosome damage following "in vivo-like" dermal exposures...
  4. ncbi An evaluation of the genotoxicity of the antitussive drug Dextromethorphan
    Marilyn J Aardema
    The Procter and Gamble Co, Miami Valley Innovation Center, P O Box 538707, Cincinnati, OH 45253, USA
    Regul Toxicol Pharmacol 50:285-93. 2008
    ....
  5. doi International prevalidation studies of the EpiDerm 3D human reconstructed skin micronucleus (RSMN) assay: transferability and reproducibility
    Marilyn J Aardema
    Procter and Gamble, Miami Valley Laboratories, 11810 East Miami River Road, Cincinnati, OH 45253, USA
    Mutat Res 701:123-31. 2010
    ....
  6. doi Evaluation of the genotoxicity of the imidazole antifungal climbazole: comparison to published results for other azole compounds
    ALEX A PEREZ-RIVERA
    The Procter and Gamble Company, Sharon Woods Innovation Center, Cincinnati, OH 45241, USA
    Mutat Res 672:27-39. 2009
    ..Collectively, these data are supportive of the view that climbazole does not present a genotoxic or carcinogenic risk to humans...
  7. ncbi SFTG international collaborative study on in vitro micronucleus test III. Using CHO cells
    Marilyn J Aardema
    Procter and Gamble Co, Miami Valley Laboratories, Cincinnati, OH 45253 8707, USA
    Mutat Res 607:61-87. 2006
    ..No differences were seen in the sensitivity or accuracy of the responses in the presence of absence of cytochalasin B. Overall, these results demonstrate the suitability of Chinese hamster ovary cells for the in vitro micronucleus assay...
  8. doi A review of biomonitoring studies measuring genotoxicity in humans exposed to hair dyes
    R Julian Preston
    The Procter and Gamble Co, Cincinnati, OH 45241, USA
    Mutagenesis 25:17-23. 2010
    ..In this paper, each study is critically reviewed and interpreted. Overall, there is no consistent evidence of genotoxicity in humans exposed to hair dyes occupationally or through individual use...
  9. ncbi Development of a method for assessing micronucleus induction in a 3D human skin model (EpiDerm)
    Rodger D Curren
    Institute for In Vitro Sciences Inc, 21 Firstfield Road, Suite 220, Gaithersburg, MD 20878, USA
    Mutat Res 607:192-204. 2006
    ..It is hoped that other investigators utilize these methods to further the understanding of this potentially valuable new non-animal method...
  10. ncbi Laboratory variability does not preclude identification of biological functions impacted by hydroxyurea
    Arne Muller
    Drug Safety Evaluation, Sanofi Aventis, Vitry sur Seine, France
    Environ Mol Mutagen 46:221-35. 2005
    ..The genes identified in our study provide information that is relevant to HU biology...
  11. ncbi SFTG international collaborative study on in vitro micronucleus test I. General conditions and overall conclusions of the study
    Elisabeth Lorge
    Servier Group, Drug Safety Assessment, Orleans Gidy, France
    Mutat Res 607:13-36. 2006
    ....