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Publications
Does perspective-taking increase patient satisfaction in medical encounters?Benjamin Blatt
Department of Medicine, CLASS Clinical Skills Center, George Washington University School of Medicine and Health Sciences, Washington, DC, USA
Acad Med 85:1445-52. 2010..To assess whether perspective-taking, which researchers in other fields have shown to induce empathy, improves patient satisfaction in encounters between student-clinicians and standardized patients (SPs)...- The nerve-heart connection in the pro-oxidant response to Mg-deficiencyMaria Isabel Tejero-Taldo
Dept of Biochemistry and Molecular Biology, Div of Experimental Medicine, The George Washington University Medical Center, Washington, DC 20037, USA
Heart Fail Rev 11:35-44. 2006.... - Instruction in behavior modification can significantly alter soil-transmitted helminth (STH) re-infection following therapeutic de-wormingJulia W Albright
Department of Microbiology, Immunology and Tropical Medicine, The George Washington University School of Medicine, Washington, DC 20037, USA
Southeast Asian J Trop Med Public Health 37:48-57. 2006.... - Acute cyanide poisoning in prehospital care: new challenges, new tools for interventionTee Guidotti
Division of Occupational Medicine and Toxicology, Department of Medicine, School of Medicine and Health Sciences, The George Washington University Medical Center, Washington, DC, USA
Prehosp Disaster Med 21:s40-8. 2006..If introduced in the U.S., hydroxocobalamin may enhance the role of the U.S. prehospital responder in providing emergency care in a cyanide incident... - A systematic review of spiritual and religious variables in Palliative Medicine, American Journal of Hospice and Palliative Care, Hospice Journal, Journal of Palliative Care, and Journal of Pain and Symptom ManagementChristina M Puchalski
George Washington Institute for Spirituality and Health GWish, George Washington University, 2300 K Street N W, 303, Washington, DC 20037, USA
Palliat Support Care 1:7-13. 2003..This paper seeks to. empirically and systematically examine the extent to which there is an adequate scientific research base on spirituality and its role in palliative care, in the palliative care and hospice literature... - Intracytoplasmic maturation of the human immunodeficiency virus type 1 reverse transcription complexes determines their capacity to integrate into chromatinSergey Iordanskiy
Department of Microbiology, Immunology and Tropical Medicine, The George Washington University, Washington, DC 20037, USA
Retrovirology 3:4. 2006..Molecular details and temporal organization of these processes remain among the least investigated and most controversial problems in the biology of HIV... - Common determinants of single channel conductance within the large cytoplasmic loop of 5-hydroxytryptamine type 3 and alpha4beta2 nicotinic acetylcholine receptorsTim G Hales
Department of Pharmacology and Physiology, George Washington University, Washington, DC 20037, USA
J Biol Chem 281:8062-71. 2006..This locus may be a common determinant of ion conduction throughout the Cys loop receptor family... - The reflective practitioner: reaching for excellence in practiceMargaret M Plack
Department of Health Care Services, George Washington University School of Medicine and Health Sciences, Washington, DC 20037, USA
Pediatrics 116:1546-52. 2005 - Triazine herbicides and epithelial ovarian cancer risk in central CaliforniaHeather A Young
The George Washington University School of Public Health and Health Services, Department of Epidemiology and Biostatistics, Washington, DC 20037, USA
J Occup Environ Med 47:1148-56. 2005..We sought to determine whether women with ovarian cancer have increased occupational exposure to triazine herbicides... - Genetic effects on women's positive mental health: do marital relationships and social support matter?Erica L Spotts
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
J Fam Psychol 19:339-49. 2005..Together, these findings emphasize the importance of genetically informed studies in family research and the role of the environment and interpersonal relationships in promoting and improving mental health... - Thymosin beta4: actin-sequestering protein moonlights to repair injured tissuesAllan L Goldstein
Department of Biochemistry and Molecular Biology, The George Washington University School of Medicine and Health Sciences, 2300 I Street, NW, Washington, DC 20037, USA
Trends Mol Med 11:421-9. 2005..It might also have important repair functions in the pathophysiologic sequelae that are associated with actin toxicity and with septic shock, such as respiratory distress syndrome, multi-organ failure and severe tissue trauma... - Manufacturing uncertainty: contested science and the protection of the public's health and environmentDavid Michaels
Department of Environmental and Occupational Health, George Washington University School of Public Health and Health Services, 2100 M St NW, Suite 203, Washington, DC 20037, USA
Am J Public Health 95:S39-48. 2005..The public health system must ensure that scientific evidence is evaluated in a manner that assures the public's health and environment will be adequately protected... - Synaptically released and exogenous ACh activates different nicotinic receptors to enhance evoked glutamatergic transmission in the lateral geniculate nucleusJian Zhong Guo
Department of Pharmacology and Physiology, George Washington University, School of Medicine and Health Sciences, DC 20037, USA
J Neurophysiol 94:2549-60. 2005.... - PDA power at the bedsidePatricia Wilson
Himmelfarb Health Sciences Library, The George Washington University, DC 20037, USA
Med Ref Serv Q 24:1-9. 2005..A low response rate of 74 questionnaires (23% of participants) was received and analyzed in March 2004. As additional funding becomes available, PDA software will be seriously considered as additions to the collection... - Evaluation of scientific evidence in law, adjudication and policy: when occupational health takes the witness chairT L Guidotti
The George Washington University Medical Center, Washington, DC 20052, USA
Med Lav 97:167-74. 2006..This emerging approach is called "evidence-based medical dispute resolution"... - Global pediatric environmental healthTee L Guidotti
Department of Environmental and Occupational Health, School of Public Health and Health Services, George Washington University Medical Center, 2100 M Street, NW, Suite 203, Washington, DC 20052, USA
Pediatr Clin North Am 54:335-50, ix. 2007..Protecting the health of children requires strengthening the public health and medical systems in every country, rather than a single global agenda... - Concurrent validity of the Early Intervention Developmental Profile and the Peabody Developmental Motor Scale-2Joyce R Maring
Program in Physical Therapy, George Washington University, Washington, DC 20037, USA
Pediatr Phys Ther 19:116-20. 2007..The purpose of this study was to determine the concurrent validity of the Early Intervention Developmental Profile (EIDP) and the Peabody Developmental Motor Scale-2 (PDMS-2) in examining gross motor delay... - The contribution of nursing to high-value inpatient careEllen T Kurtzman
The George Washington University, Washington, DC 20037, USA
Policy Polit Nurs Pract 11:36-61. 2010..Recommendations are made to strengthen the nurse-value case and convince health care stakeholders, including policy makers, that the relationship is established, enduring, and sufficient for national action... - Molecular diagnosis of neonatal sepsisJeanne A Jordan
Department of Epidemiology and Biostatistics, School of Public Health and Health Services, The George Washington University, 231 Ross Hall, 2300 Eye Street, NW, Washington, DC 20037, USA
Clin Perinatol 37:411-9. 2010..Although considerable hurdles remain, this challenge is now a priority for investigators in academia and industry... - Helminth genomics: The implications for human healthPaul J Brindley
Department of Microbiology, Immunology, and Tropical Medicine, George Washington University Medical Center, Washington, D C, USA
PLoS Negl Trop Dis 3:e538. 2009..They are likely also to predict new potential vaccine candidates and drug targets. In this review, we present an overview of these efforts and emphasize the potential impact and importance of these new findings... - Specific relation between abdominal obesity and early-phase hyperglycemia is modulated by hepatic insulin resistance in healthy older womenLoretta Dipietro
John B Pierce Laboratory, Yale University School of Medicine, New Haven, Connecticut, USA
Diabetes Care 33:165-7. 2010..To describe the impact of abdominal obesity and hepatic insulin resistance on phase-specific glycemic responses in older women... - Prediction of birth weight by cotinine levels during pregnancy in a population of black smokersAyman A E El-Mohandes
Department of Prevention and Community Health, School of Public Health and Health Services, George Washington University Medical Center, 2175 K St NW, Suite 700, Washington, DC 20037, USA
Pediatrics 124:e671-80. 2009..The goal was to investigate the association between maternal salivary cotinine levels (SCLs) and pregnancy outcomes among black smokers... - Measuring equity: an index of health care disparitiesBruce Siegel
Department of Health Policy, School of Public Health and Health Services, The George Washington University, Washington, DC, USA
Qual Manag Health Care 18:84-90. 2009..To create an index that would serve as a simple tool to measure the quality of hospital care by race and ethnicity... - Commentary: the ACGME: fostering public trust and addressing residents' needsJordan J Cohen
George Washington University, Washington, DC 20037, USA
Acad Med 84:291-2. 2009..Residents are advised to ignore the seductive appeals of organized labor because of what the specter of unionized physicians is likely to do to public trust in the medical profession... - Aurum: a case study in the politics of NIMBYTee L Guidotti
Department of Public Health Sciences, Faculty of Medicine, University of Alberta, Edmonton, Alberta, Canada
Waste Manag Res 26:582-8. 2008..It was concluded that in this instance, and probably many others, the political history of the community plays a major role in conditioning their response to ;locally undesirable land use' (LULUs) and the NIMBY phenomenon... - Increasing transparency at the FDA: the impact of the FDA Amendments Act of 2007Susan F Wood
The George Washington University School of Public Health and Health Services, Washington DC 20052, USA
Public Health Rep 123:527-30. 2008 - Quality improvements in end of life care: insights from two collaborativesJ Lynn
Center to Improve Care of the Dying, RAND, USA
Jt Comm J Qual Improv 26:254-67. 2000..Coordinated efforts in two Breakthrough Series produced generalizable insights... - Coinfection with Heligmosomoides polygyrus fails to establish CD8+ T-cell immunity against Toxoplasma gondiiImtiaz A Khan
Department of Microbiology and Tropical Medicine and Immunology, George Washington University, Washington, DC 20037, USA
Infect Immun 76:1305-13. 2008.... - DC Water and Sewer Authority and lead in drinking water: a case study in environmental health risk managementTee L Guidotti
Department of Environmental and Occupational Health, School of Public Health and Health Services, The George Washington University, 2100 M St, NW, Suite 203, Washington, DC 20052, USA
J Public Health Manag Pract 14:33-41. 2008..This case study examines the lessons learned... - A study of Gulf War veterans with a possible deployment-related syndromePaul H Levine
Department of Epidemiology and Biostatistics, George Washington University School of Public Health and Health Services, Washington, DC 20037, USA
Arch Environ Occup Health 61:271-8. 2006..Many of the neurological symptoms reported by the studied veterans appear to have an organic basis, but comorbidities must be excluded before researchers can conclude that a definitive syndrome exists... - Children's susceptibility to chemicals: a review by developmental stageAnna Makri
George Washington University, Center for Risk Science and Public Health, 2100 M Street, NW, Suite 203, Washington, DC 20052, USA
J Toxicol Environ Health B Crit Rev 7:417-35. 2004..This approach may be useful for evaluating developmental trends of susceptibility, and for identifying time periods and/or chemical classes of particular concern and thus important to consider in risk assessment... - A hard way to the nucleusMichael Bukrinsky
The George Washington University Medical Center, 2300 Eye Street NW, Ross Hall Room 734, Washington, DC 20037, USA
Mol Med 10:1-5. 2004..In this review, we will discuss recent advances and suggest possible solutions to the controversial issue of HIV-1 nuclear import... - A content analysis of hiv/aids information in psychology textbooks: implications for education, training, and practiceF Y Wong
George Washington University School of Public Health and Health Services, Washington, DC 20006, USA
AIDS Educ Prev 13:561-70. 2001..Implications for education, training, and practices are discussed... - Genetic probes of three theories of maternal adjustment: II. Genetic and environmental influencesD Reiss
Center for Research, George Washington University, Ross Hall 613, 2300 I Street NW, Washington, DC 20037, USA
Fam Process 40:261-72. 2001..Our model did not include these influences and thus must be amended... - Pediatric advocacyJ A Paulson
Department of Community Health, School of Public Health and Health Services, Mid Atlantic Center for Children s Health and the Environment, George Washington University, Washington, DC, USA
Pediatr Clin North Am 48:1307-18. 2001..When asked why they, as bench scientists, ventured out of the laboratory as advocates, Rowland stated, "If not me, who? If not now, when?" (personal communication, December 7, 2000)... - The histopathology of 103 consecutive colonoscopy biopsies from 82 symptomatic patients with acquired immunodeficiency syndrome: original and look-back diagnosesJ M Orenstein
Department of Pathology, George Washington University Medical Center, 2300 Eye Street NW, Washington, DC 20037, USA
Arch Pathol Lab Med 125:1042-6. 2001.... - Nonpalpable breast cancer: percutaneous diagnosis with 11- and 8-gauge stereotactic vacuum-assisted biopsy devicesR F Brem
Department of Radiology, Breast Imaging and Interventional Center, George Washington University Medical Center, 2150 Pennsylvania Ave, Washington, DC 20037, USA
Radiology 219:793-6. 2001..To compare the accuracy of diagnosis of invasive breast cancer with 11- and 8-gauge stereotactic vacuum-assisted biopsy (SVAB) devices and to correlate lesion diameter and accuracy of breast cancer diagnosis at SVAB... - Development of the gravity sensing systemK D Peusner
Department of Anatomy and Cell Biology, George Washington University Medical Center, 2300 I Street N W, Washington, DC 20037, USA
J Neurosci Res 63:103-8. 2001..This is related to the evidence suggesting that recovery of function in different systems and cell lines, including neurons, involves repeating certain patterns established during development... - Cardiac tissue iron: effects on post-ischemic function and free radical production, and its possible role during preconditioningJ H Kramer
Department of Physiology and Experimental Medicine, The George Washington University Medical Center, Washington, DC 20037, USA
Cell Mol Biol (Noisy-le-grand) 46:1313-27. 2000..These preliminary findings suggest that cardioprotection resulting from IP may, in part, be related to IP-induced release of cardiovascular endothelial iron (redox-active) prior to imposing severe I/R stress... - Multiple measurements of depression predict mortality in a longitudinal study of chronic hemodialysis outpatientsP L Kimmel
Department of Medicine and Psychiatry and Behavioral Sciences, School of Medicine, George Washington University Medical Center, Washington, DC 20037, USA
Kidney Int 57:2093-8. 2000..We sought to determine whether depressive affect is associated with mortality in a longitudinal study of end-stage renal disease (ESRD) patients treated with HD, using multiple assessments over time... - Intralesional cidofovir for recurrent laryngeal papillomas: preliminary reportW R Wilson
Division of Otolaryngology Head and Neck Surgery, George Washington University Medical Center, Washington, DC 20037, USA
Ear Nose Throat J 79:236-8, 240. 2000..We conclude that intralesional cidofovir appears to be a promising new treatment for controlling--and perhaps at higher dosages curing--refractory laryngeal papillomas, while causing little or no injury to laryngeal structures... - Soluble receptors and other substances that regulate proinflammatory cytokines in young and aging humansJ W Albright
Department of Microbiology and Immunology, George Washington University School of Medicine, Washington, DC 20037, USA
J Gerontol A Biol Sci Med Sci 55:B20-5. 2000..The results of this study highlight the need for further studies of the roles played by soluble receptors, and similar agonists/antagonists, in the immune responses of aged adults... - The Fort McMurray Demonstration Project in Social Marketing: theory, design, and evaluationT L Guidotti
Northern Centre for Work, Environment and Health, Edmonton, Alberta, Canada
Am J Prev Med 18:163-9. 2000..VENUE: Fort McMurray, in the province of Alberta, Canada, was selected because the community had several community initiatives already underway and the project had the opportunity to demonstrate "value added.".. - Growth inhibitory effects of 1,25-dihydroxyvitamin D3 and its synthetic analogue, 1alpha,25-dihydroxy-16-ene-23yne-26,27-hexafluoro-19-nor-cholecalcifero l (Ro 25-6760), on a human colon cancer xenograftS R Evans
Department of Surgery, George Washington University Medical Center, Washington, DC 20037, USA
Clin Cancer Res 4:2869-76. 1998..The mechanism for this impressive growth inhibition is not yet elucidated and warrants further investigation... - The Warthin-Finkeldey-type giant cell in HIV infection, what is it?J M Orenstein
Department of Pathology, George Washington University, Washington, DC, USA
Ultrastruct Pathol 22:293-303. 1998..TEM and ISH revealed evidence of HIV expression by FDC, but not WFTGC. WFTGC in HIV- lymphoid specimens displayed identical LM and IHC characteristics. The WFTGC in HIV infection appears to represent a multinucleated form of FDC... - The modern medical school graduate and general surgical training: are they compatible?Stephen Evans
Department of Surgery, George Washington University Medical Center, 2150 Pennsylvania Ave NW, Washington, DC 20037, USA
Arch Surg 137:274-7. 2002 - Cost effectiveness of treatment for benign prostatic hyperplasia: an economic model for comparison of medical, minimally invasive, and surgical therapyMichael J Manyak
Department of Urology, The George Washington University Medical Center, Washington, DC 20037, USA
J Endourol 16:51-6. 2002..To evaluate the cost effectiveness of minimally invasive therapy relative to medical (alpha-blocker) therapy and transurethral resection (TURP) for patients with moderate to severe symptoms of benign prostatic hyperplasia (BPH)... - Spirituality and end-of-life care: a time for listening and caringChristina M Puchalski
Departments of Medicine and Health Care Sciences, The George Washington Institute for Spirituality and Health, GWU Medical Center, 2300 K Street NW, Warwick Building #336, Washington, D.C. 20037, USA
J Palliat Med 5:289-94. 2002 - Prenatal nicotine exposure alters central cardiorespiratory responses to hypoxia in rats: implications for sudden infant death syndromeRobert A Neff
Department of Pharmacology and Physiology, The George Washington University, Washington, DC 20037, USA
J Neurosci 24:9261-8. 2004..This study establishes a likely neurochemical mechanism for the heart rate response to hypoxia and a link between prenatal nicotine exposure and an exaggerated bradycardia during hypoxia that may contribute to SIDS... - From progress to regression: biomedical research fundingH George Mandel
Department of Pharmacology and Physiology, School of Medicine and Health Sciences, The George Washington University, Washington, DC 20037, USA
J Clin Invest 114:872-6. 2004..This article focuses on select attempts to sustain the record of scientific achievement enabled in the past by continued increasing investment and also suggests some solutions... - Should we establish a North American school of global health sciences?Peter J Hotez
Department of Microbiology and Tropical Medicine, Global Health, Epidemiology and Biostatistics, The George Washington University, Washington, DC 20037, USA
Am J Med Sci 328:71-7. 2004..The North American school, possibly in association with one of the existing schools of medicine or public health, would provide interdisciplinary training to produce a new generation of global health scientists... - Critique of (im)pure reason: evidence-based medicine and common senseJames Michelson
George Washington University School of Medicine and Health Sciences, Washington, DC, USA
J Eval Clin Pract 10:157-61. 2004..As is more fully discussed in the manuscript, this active disregard for common sense leaves us at a great disadvantage in the practical practice of medicine... - Spirituality in health: the role of spirituality in critical careChristina Puchalski
Department of Medicine, The George Washington University, 2131 K Street NW, 5th Floor, Washington, DC 20052, USA
Crit Care Clin 20:487-504, x. 2004..Spiritual beliefs can also impact how people cope with illness. By addressing spiritual issues of patients, loved ones, and ourselves, we can create more holistic and compassionate systems of care... - Induction of pro-apoptotic and cell cycle-inhibiting genes in chromium (VI)-treated human lung fibroblasts: lack of effect of ERKSusan Ceryak
Department of Pharmacology, The George Washington University Medical Center, Washington, DC 20037, USA
Mol Cell Biochem 255:139-49. 2004..Continued investigation into the cellular and molecular mechanisms of Cr(VI)-induced cell cycle and apoptosis control should further the understanding of Cr(VI)-associated carcinogenesis... - Factor analysis of fatiguing syndrome in Gulf War era veterans: implications for etiology and pathogenesisHeather A Young
School of Public Health and Health Services, George Washington University, Washington, DC 20037, USA
J Occup Environ Med 45:1268-73. 2003..Although the factors were similar for both groups, they were more differentiated in the FS group than in the control group as evidenced by interfactor correlations... - Trichomonas vaginalis among HIV-Infected women: are immune status or protease inhibitor use associated with subsequent T. vaginalis positivity?Manya Magnus
Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana, USA
Sex Transm Dis 30:839-43. 2003..The relationship between Tv and immune status and HIV viral load as affected by protease inhibitor (PI) use has not been well examined... - Atmospheric change: health/ecological linkagesTee L Guidotti
Department of Environmental and Occupational Health, School of Public Health and Health Services, The George Washington University Medical Center, 20037, Washington, DC, USA
Environ Int 29:359-64. 2003..As a practical application, ecosystem health studies describe the mechanisms and assesses the potential to threaten or enhance human health... - Target-independent specification of proprioceptive sensory neuronsRobert A Oakley
Department of Anatomy and Cell Biology, The George Washington University Medical Center, Washington, DC 20037, USA
Dev Biol 249:255-69. 2002..These results therefore indicate that the proprioceptive phenotype is specified prior to target innervation and that these neurons can retain their identity despite projecting to inappropriate (cutaneous) targets... - Measuring nicotinic receptors with characteristics of alpha4beta2, alpha3beta2 and alpha3beta4 subtypes in rat tissues by autoradiographyDavid C Perry
Department of Pharmacology, George Washington University Medical Center, Washington, DC 20037, USA
J Neurochem 82:468-81. 2002.... - The injury risk associated with pes planus in athletesJ D Michelson
Department of Orthopaedics and Rehabilitation, University of Vermont College of Medicine, Burlington, USA
Foot Ankle Int 23:629-33. 2002..The routine prophylactic use of orthotics in flat-footed athletes to prevent future injury may therefore not be justified based on the data available... - Gene expression profile of HIV-1 Tat expressing cells: a close interplay between proliferative and differentiation signalsCynthia de La Fuente
Department of Biochemistry and Molecular Biology George Washington University School of Medicine Washington DC 20037, USA
BMC Biochem 3:14. 2002..We utilized microarray analysis from uninfected, latently HIV-1 infected cells, as well as cells that express Tat, to decipher some of the cellular changes associated with this viral activator... - Color Doppler ultrasonography by emergency physicians for the diagnosis of acute deep venous thrombosisB T Jolly
Department of Emergency Medicine, George Washington University Medical Center, Washington DC 20037, USA
Acad Emerg Med 4:129-32. 1997..To assess the feasibility of emergency physicians' (EPs') performing color-flow Doppler ultrasonographic vascular studies in the ED to diagnose deep venous thrombosis (DVT), after a modest training program...
Research Grants
- HOOKWORM LARVAL INFECTIVITY AND DEVELOPMENTPeter Hotez; Fiscal Year: 2002..The pharmacologic manipulation of parasite-derived protein kinases may offer a new approach to chemotherapy by taking larvae out of arrest. ..
- Genomic analyses of autism spectrum disordersVALERIE HU; Fiscal Year: 2007..Reliable biomarkers would greatly facilitate the early and definitive detection of these disorders, thereby permitting early intervention and therapy. ..
- Leukocyte recruitment by cyclophilinc-CD147 interactionMichael Bukrinsky; Fiscal Year: 2005..This exploratory proposal is fully consistent with the goals of this PA as it extends our previous discovery toward new directions related to regulation of inflammatory responses. ..
- CD4+ memory T cell recruitment by cyclophilinMichael Bukrinsky; Fiscal Year: 2004..Therefore, the R03 mechanism appears highly appropriate. If proven, this hypothesis will serve as a foundation for a new research program, which might suggest novel approaches to treatment of HIV-1 infection. ..
- The Role of Vpr in HIV-1 Nuclear TranslocationMichael Bukrinsky; Fiscal Year: 2006..These results will be significant, because they are expected to facilitate discovery of agents that would inhibit Vpr activity and thus attenuate HIV replication. ..
- Mechanisms of virus-induced impairment of reverse cholesterol transportDmitri Sviridov; Fiscal Year: 2010..In addition, the proposed studies will define the mechanisms regulating physiological turnover of ABCA1 and thus may contribute to development of new therapeutic agents to treat atherosclerosis. ..
- Mechanisms of virus-induced impairment of reverse cholesterol transportMichael Bukrinsky; Fiscal Year: 2009..In addition, the proposed studies will define the mechanisms regulating physiological turnover of ABCA1 and thus may contribute to development of new therapeutic agents to treat atherosclerosis. ..
- HIV Disease and Impairement of High Density Lipoprotein MetabolismDmitri Sviridov; Fiscal Year: 2010..of clinical cardiologists, basic science cardiovascular researchers and virologists at three sites: the George Washington University, Harvard University and BakerlDI Heart and Diabetes Research Institute...
- Oxadaizols: Rationally designed compounds targeting HIV nuclear importationMichael Bukrinsky; Fiscal Year: 2007..These studies are highly relevant to public health as they are expected to expand the repertoire of available anti-HIV drugs, thus providing an opportunity to fight drug resistance often seen in HIV-infected patients. ..
- HIV Impairs Reverse Cholesterol TransportMichael Bukrinsky; Fiscal Year: 2006..These studies are expected to yield sufficient information upon which to base a well-planned and rigorous series of further investigations. ..
- Toddler Anxiety: Temperament/Neurophysiology & ParentingSusan Warren; Fiscal Year: 2007..Clarifying the pathways and factors that lead to the development of increasing difficulties with anxiety will provide crucial information for the innovation of intervention strategies. ..
- Panic Disorder, Parenting and Infant NeurobiologySusan Warren; Fiscal Year: 2007..This research will provide information concerning which particular factors might contribute to increasing child fear-arousal across the first 2 years of life. ..
- NUCLEAR TRANSLOCATION OF HIV 1 GENOME AS A DRUG TARGETMichael Bukrinsky; Fiscal Year: 2004..Upon completion, these studies are expected to define potent anti-HIV compounds working through a novel mechanism different from that of any other currently used drug. ..
- EARLY DEVELOPMENTAL PATHWAYS OF CHILDHOOD ANXIETYSusan Warren; Fiscal Year: 2002....
- NUCLEAR TRANSLOCATION OF HIV1 GENOME AS A DRUG TARGETMichael Bukrinsky; Fiscal Year: 1999..They will analyze anti-viral effects of these compounds in different cell targets using various activation conditions. These studies are expected to lay a foundation for introducing anti-NLS compounds as new anti-HIV drugs. ..
- Imaging Technology for HIV Nuclear Import InhibitorsMichael Bukrinsky; Fiscal Year: 2003..The imaging technology will greatly augment the value of the project by adding a superior method for analyzing the activity of the drugs. ..
- SYNAPTIC TRANSMISSION DURING NEURONAL DIFFERENTIATIONKenna D Peusner; Fiscal Year: 2010....
- SYNAPTIC TRANSMISSION DURING NEURONAL DIFFERENTIATIONKENNA PEUSNER; Fiscal Year: 2007..abstract_text> ..
- SYNAPTIC TRANSMISSION DURING NEURONAL DIFFERENTIATIONKENNA PEUSNER; Fiscal Year: 1993..In addition, these studies should contribute to our understanding of how the vestibular system begins to function and the role of functional activity on neuron differentiation and neuron survival...
- SYNAPTIC TRANSMISSION DURING NEURONAL DIFFERENTIATIONKENNA PEUSNER; Fiscal Year: 2003..abstract_text> ..
- DEVELOPMENT OF VESTIBULAR NUCLEI NEURONSKENNA PEUSNER; Fiscal Year: 2005..abstract_text> ..