Bao-Hong Zhang

Summary

Affiliation: Texas Tech University
Country: USA

Publications

  1. ncbi request reprint Identification and characterization of new plant microRNAs using EST analysis
    Bao Hong Zhang
    The Institute of Environmental and Human Health, and Department of Environmental Toxicology, Texas Tech University, Lubbock, TX 79409 1163, USA
    Cell Res 15:336-60. 2005
  2. ncbi request reprint Computational identification of microRNAs and their targets
    Baohong Zhang
    The Institute of Environmental and Human Health, Department of Environmental Toxicology, Texas Tech University, Lubbock, TX 79409 1163, USA
    Comput Biol Chem 30:395-407. 2006
  3. ncbi request reprint MicroRNAs and their regulatory roles in animals and plants
    Baohong Zhang
    The Institute of Environmental and Human Health, and Department of Environmental Toxicology, Texas Tech University, Lubbock, Texas 79409, USA
    J Cell Physiol 210:279-89. 2007
  4. ncbi request reprint microRNAs as oncogenes and tumor suppressors
    Baohong Zhang
    Department of Environmental Toxicology, The Institute of Environmental and Human Health, Texas Tech University, Lubbock, TX 79409 1163, USA
    Dev Biol 302:1-12. 2007
  5. ncbi request reprint MicroRNA: a new player in stem cells
    Baohong Zhang
    The Institute of Environmental and Human Health TIEHH, and Department of Environmental Toxicology, Texas Tech University, Lubbock, Texas 79409 1163, USA
    J Cell Physiol 209:266-9. 2006
  6. ncbi request reprint Identification of 188 conserved maize microRNAs and their targets
    Baohong Zhang
    The Institute of Environmental and Human Health, Department of Environmental Toxicology, Texas Tech University, Lubbock, TX 79409 1163, USA
    FEBS Lett 580:3753-62. 2006
  7. ncbi request reprint Plant microRNA: a small regulatory molecule with big impact
    Baohong Zhang
    The Institute of Environmental and Human Health TIEHH, and Department of Environmental Toxicology, Texas Tech University, Lubbock, 79409 1163, USA
    Dev Biol 289:3-16. 2006
  8. ncbi request reprint Measuring gene flow in the cultivation of transgenic cotton (Gossypium hirsutum L.)
    Bao Hong Zhang
    The Institute of Environmental and Human Health, and Department of Environmental Toxicology, Texas Technical University, Lubbock, TX 79409, USA
    Mol Biotechnol 31:11-20. 2005
  9. ncbi request reprint Determination of N-nitroso derivatives of hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) in soils by pressurized liquid extraction and liquid chromatography-electrospray ionization mass spectrometry
    Xiaoping Pan
    The Institute of Environmental and Human Health, Department of Environmental Toxicology, Texas Tech University, Lubbock, TX 79409 1163, USA
    J Chromatogr A 1107:2-8. 2006
  10. ncbi request reprint Toxicity of the explosive metabolites hexahydro-1,3,5-trinitroso-1,3,5-triazine (TNX) and hexahydro-1-nitroso-3,5-dinitro-1,3,5-triazine (MNX) to the earthworm Eisenia fetida
    Baohong Zhang
    The Institute of Environmental and Human Health TIEHH, Department of Environmental Toxicology, Texas Tech University, Lubbock, TX 79409 1163, USA
    Chemosphere 64:86-95. 2006

Collaborators

Detail Information

Publications26

  1. ncbi request reprint Identification and characterization of new plant microRNAs using EST analysis
    Bao Hong Zhang
    The Institute of Environmental and Human Health, and Department of Environmental Toxicology, Texas Tech University, Lubbock, TX 79409 1163, USA
    Cell Res 15:336-60. 2005
    ..Environmental stresses and developmental switching may be the signals for synthesis and regulation of miRNAs in plants. A model for miRNA induction and expression, and gene regulation by miRNA is hypothesized...
  2. ncbi request reprint Computational identification of microRNAs and their targets
    Baohong Zhang
    The Institute of Environmental and Human Health, Department of Environmental Toxicology, Texas Tech University, Lubbock, TX 79409 1163, USA
    Comput Biol Chem 30:395-407. 2006
    ..A majority of known miRNAs and their targets were identified by computational approaches. Several web-based or non-web-based computer software programs are publicly available for predicting miRNAs and their targets...
  3. ncbi request reprint MicroRNAs and their regulatory roles in animals and plants
    Baohong Zhang
    The Institute of Environmental and Human Health, and Department of Environmental Toxicology, Texas Tech University, Lubbock, Texas 79409, USA
    J Cell Physiol 210:279-89. 2007
    ..This review provides a general background and current advance on the discovery, history, biogenesis, genomics, mechanisms, and functions of miRNAs...
  4. ncbi request reprint microRNAs as oncogenes and tumor suppressors
    Baohong Zhang
    Department of Environmental Toxicology, The Institute of Environmental and Human Health, Texas Tech University, Lubbock, TX 79409 1163, USA
    Dev Biol 302:1-12. 2007
    ..miRNA expression profiles may become useful biomarkers for cancer diagnostics. In addition, miRNA therapy could be a powerful tool for cancer prevention and therapeutics...
  5. ncbi request reprint MicroRNA: a new player in stem cells
    Baohong Zhang
    The Institute of Environmental and Human Health TIEHH, and Department of Environmental Toxicology, Texas Tech University, Lubbock, Texas 79409 1163, USA
    J Cell Physiol 209:266-9. 2006
    ..Some miRNAs are specifically expressed in stem cells, control stem cell self-renewal, and differentiation through negatively regulating the expression of certain key genes in stem cells...
  6. ncbi request reprint Identification of 188 conserved maize microRNAs and their targets
    Baohong Zhang
    The Institute of Environmental and Human Health, Department of Environmental Toxicology, Texas Tech University, Lubbock, TX 79409 1163, USA
    FEBS Lett 580:3753-62. 2006
    ..Some of the newly identified miRNA targets may be unique to maize...
  7. ncbi request reprint Plant microRNA: a small regulatory molecule with big impact
    Baohong Zhang
    The Institute of Environmental and Human Health TIEHH, and Department of Environmental Toxicology, Texas Tech University, Lubbock, 79409 1163, USA
    Dev Biol 289:3-16. 2006
    ..miRNAs regulate the expression of many important genes; a majority of these genes are transcriptional factors...
  8. ncbi request reprint Measuring gene flow in the cultivation of transgenic cotton (Gossypium hirsutum L.)
    Bao Hong Zhang
    The Institute of Environmental and Human Health, and Department of Environmental Toxicology, Texas Technical University, Lubbock, TX 79409, USA
    Mol Biotechnol 31:11-20. 2005
    ..In this experiment, the farthest distance of pollen dispersal from transgenic cotton was 50 m. These results indicate that a 60-m buffer zone would serve to limit dispersal of transgenic pollen from small-scale field tests...
  9. ncbi request reprint Determination of N-nitroso derivatives of hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) in soils by pressurized liquid extraction and liquid chromatography-electrospray ionization mass spectrometry
    Xiaoping Pan
    The Institute of Environmental and Human Health, Department of Environmental Toxicology, Texas Tech University, Lubbock, TX 79409 1163, USA
    J Chromatogr A 1107:2-8. 2006
    ..1-108.3%), good precision (RSD: 3.2-12.4%), and reproducibility were achieved. This method proved effective and was applied to monitor the reductive biotransformation of MNX in soils with the presence of earthworms (Eisenia fetida)...
  10. ncbi request reprint Toxicity of the explosive metabolites hexahydro-1,3,5-trinitroso-1,3,5-triazine (TNX) and hexahydro-1-nitroso-3,5-dinitro-1,3,5-triazine (MNX) to the earthworm Eisenia fetida
    Baohong Zhang
    The Institute of Environmental and Human Health TIEHH, Department of Environmental Toxicology, Texas Tech University, Lubbock, TX 79409 1163, USA
    Chemosphere 64:86-95. 2006
    ..LC20 and LC50 for TNX were slightly lower than for MNX; this indicates that TNX was more toxic than MNX. No significant morphological or developmental abnormalities were observed in earthworms surviving exposure...
  11. ncbi request reprint Assessment of pathogens and toxicants in New Orleans, LA following Hurricane Katrina
    Steven M Presley
    Department of Environmental Toxicology, The Institute of Environmental and Human Health, Texas Tech University, Lubbock 79409 1163, USA
    Environ Sci Technol 40:468-74. 2006
    ..Initial findings suggest numerous environmental contaminants are present in New Orleans and support the need for further evaluation of the extent of those threats...
  12. doi request reprint Uptake, bioaccumulation, and biodegradation of hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) and its reduced metabolites (MNX and TNX) by the earthworm (Eisenia fetida)
    Baohong Zhang
    Department of Environmental Toxicology, The Institute of Environmental and Human Health, Texas Tech University, Lubbock, TX 79409 1163, USA
    Chemosphere 76:76-82. 2009
    ..It is hoped that these data can be used to refine environmental management strategies for RDX and for performing specific risk assessments of RDX and its N-nitroso metabolites...
  13. ncbi request reprint Conservation and divergence of plant microRNA genes
    Baohong Zhang
    The Institute of Environmental and Human Health TIEHH, and Department of Environmental Toxicology, Texas Tech University, Lubbock, TX 79409 1163, USA
    Plant J 46:243-59. 2006
    ..Regulation of gene expression by miRNAs appears to have existed at the earliest stages of plant evolution and has been tightly constrained (functionally) for more than 425 million years...
  14. ncbi request reprint Examination of the mutagenicity of RDX and its N-nitroso metabolites using the Salmonella reverse mutation assay
    Xiaoping Pan
    The Institute of Environmental and Human Health TIEHH, Department of Environmental Toxicology, Texas Tech University, Lubbock, TX 79409 1163, USA
    Mutat Res 629:64-9. 2007
    ..Strain TA97a was found to be the most sensitive strain among these four strains. No cytotoxicity of RDX, MNX, and TNX was observed at the concentrations used in this study. Doses were verified by HPLC...
  15. ncbi request reprint N-Nitroso compounds produced in deer mouse (Peromyscus maniculatus) GI tracts following hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) exposure
    Xiaoping Pan
    The Institute of Environmental and Human Health, Department of Environmental Toxicology, Texas Tech University, Lubbock, TX 79409 1163, USA
    Chemosphere 67:1164-70. 2007
    ..DNX in stomach were 217 microg/kg for the 10mg/kg dose group and 498 microg/kg for the 100mg/kg dose group. Changes in other toxic endpoints including body weight gain, food consumption, organ weight, and behavior were also reported...
  16. ncbi request reprint Liquid chromatography/electrospray ionization tandem mass spectrometry analysis of octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine (HMX)
    Xiaoping Pan
    The Institute of Environmental and Human Health TIEHH, and Department of Environmental Toxicology, Texas Tech University, Lubbock, TX 79409 1163, USA
    Rapid Commun Mass Spectrom 20:2222-6. 2006
    ..Using this quantification technique, the method detection limit was 1.57 microg/L and good linearity was achieved in the range 5-500 microg/L. This method will help to unambiguously analyze environmentally relevant concentrations of HMX...
  17. ncbi request reprint Use of pressurized liquid extraction (PLE)/gas chromatography-electron capture detection (GC-ECD) for the determination of biodegradation intermediates of hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) in soils
    Baohong Zhang
    The Institute of Environmental and Human Health TIEHH, and Department of Environmental Toxicology, Texas Tech University, Lubbock, TX 79409 1163, USA
    J Chromatogr B Analyt Technol Biomed Life Sci 824:277-82. 2005
    ..243, 0.095, 0.138, and 0.057 ng/g for RDX, MNX, DNX, and TNX, respectively. The method gave high recovery (98-102%), good precision (0.22-5.14%), and reproducibility, and proved to be suitable for real world sample analysis...
  18. ncbi request reprint Evaluating the bioavailability of explosive metabolites, hexahydro-1-nitroso-3,5-dinitro-1,3,5-triazine (MNX) and hexahydro-1,3,5-trinitroso-1,3,5-triazine (TNX), in soils using passive sampling devices
    Baohong Zhang
    The Institute of Environmental and Human Health TIEHH, Department of Environmental Toxicology, Texas Tech University, Lubbock, TX 79409 1163, USA
    J Chromatogr A 1101:38-45. 2006
    ..These data indicate that C18 PSDs may be used as a surrogate for soil organisms such as earthworms and provide a simple and easy chemical test for assessing the bioavailability of contaminants in soils...
  19. ncbi request reprint Effects of hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) metabolites on cricket (Acheta domesticus) survival and reproductive success
    Baohong Zhang
    The Institute of Environmental and Human Health TIEHH, and Department of Environmental Toxicology, Texas Tech University, Box 41163, Lubbock, TX 79409 1163, USA
    Environ Pollut 144:540-4. 2006
    ..No gross abnormalities in cricket nypmhs were observed in all experiments indicating that neither TNX or MNX is teratogenic in this assay...
  20. ncbi request reprint Effect of two major N-nitroso hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) metabolites on earthworm reproductive success
    Baohong Zhang
    The Institute of Environmental and Human Health, Department of Environmental Toxicology, Texas Tech University, Lubbock, TX 79409, USA
    Environ Pollut 153:658-67. 2008
    ..7mg/kg for MNX and TNX, respectively, in soil and 4.5 and 3.1mg/L in the topical test. Both MNX and TNX inhibited cocoon production and hatching, suggesting that they may have a negative affect on soil ecosystems at contaminated sites...
  21. ncbi request reprint Effects of perchlorate on earthworm (Eisenia fetida) survival and reproductive success
    Mindy Landrum
    The Institute of Environmental and Human Health, Texas Tech University, Lubbock, TX, United States
    Sci Total Environ 363:237-44. 2006
    ..In addition, preliminary data suggest that cocoons produced under perchlorate contamination did not hatch as well as cocoons produced in control soil despite incubation of both sets of cocoons in clean soil or sand...
  22. doi request reprint Assessment of organochlorine pesticides and metals in ring-tailed lemurs (Lemur catta) at Beza Mahafaly Special Reserve, Madagascar
    Thomas R Rainwater
    Department of Environmental Toxicology, The Institute of Environmental and Human Health, Texas Tech University, Lubbock, Texas, USA
    Am J Primatol 71:998-1010. 2009
    ....
  23. ncbi request reprint Characterizing viral microRNAs and its application on identifying new microRNAs in viruses
    Xiaoping Pan
    The Institute of Environmental and Human Health, and Department of Environmental Toxicology, Texas Tech University, Lubbock, Texas, USA
    J Cell Physiol 211:10-8. 2007
    ..A better understanding of viral miRNA functions will be useful to design new approaches for treating viruses, especially those viruses that can induce human, animal, and plant diseases...
  24. doi request reprint Organochlorine pesticide concentrations in sediment and amphibian tissue in playa wetlands in the southern high plains, USA
    Louise S Venne
    Department of Environmental Toxicology, The Institute of Environmental and Human Health, Texas Tech University, MS 1163, Lubbock, TX 79409, USA
    Bull Environ Contam Toxicol 80:497-501. 2008
    ..However, mean DDT and DDE reached 19.7 and 4.1 ng/g in sediments and 6.3 and 2.4 ng/g in tissues, respectively. Land use did not influence pesticide levels in sediment or amphibians...
  25. doi request reprint Development of a method for the determination of 9 currently used cotton pesticides by gas chromatography with electron capture detection
    Baohong Zhang
    Department of Environmental Toxicology, The Institute of Environmental and Human Health, Texas Tech University, Lubbock, TX 79409 1163, United States
    Talanta 75:1055-60. 2008
    ..After 10 days storage at room temperature, 30-40% degradation of lambda-cyhalothrin was observed. It is recommended that acephate, acetamiprid, and lambda-cyhalothrin be stored at -20 degrees C or analyzed immediately after extraction...
  26. ncbi request reprint Ethanol reduces p38 kinase activation and cyclin D1 protein expression after partial hepatectomy in rats
    Michael K H Hsu
    Storr Liver Unit, Westmead Millennium Institute, Westmead Hospital and University of Sydney, Westmead, NSW 2145, Australia
    J Hepatol 44:375-82. 2006
    ..Chronic ethanol consumption inhibits liver regeneration. We examined the effects of chronic ethanol consumption on two mitogen-activated protein kinases in relation to induction of cell cycle proteins after partial hepatectomy (PH)...