Seung Hee Yoo
Affiliation: Texas Medical Center
Yoo S, Kojima S, Shimomura K, Koike N, Buhr E, Furukawa T, et al
. Period2 3'-UTR and microRNA-24 regulate circadian rhythms by repressing PERIOD2 protein accumulation. Proc Natl Acad Sci U S A. 2017;114:E8855-E8864 pubmed publisher
..Together, these studies provide important mechanistic insights into the regulatory roles of Per2 3'-UTR, miR-24, and PER2 in Per2 expression and core clock function. ..
Ye Y, Xiang Y, Ozguc F, Kim Y, Liu C, Park P, et al
. The Genomic Landscape and Pharmacogenomic Interactions of Clock Genes in Cancer Chronotherapy. Cell Syst. 2018;6:314-328.e2 pubmed publisher
..Our study provides a comprehensive analysis of the circadian clock across different cancer types and highlights potential clinical utility of cancer chronotherapy. ..
Nohara K, Chen Z, Yoo S. A Filtration-based Method of Preparing High-quality Nuclei from Cross-linked Skeletal Muscle for Chromatin Immunoprecipitation. J Vis Exp. 2017;: pubmed publisher
..In combination with next-generation sequencing (NGS), our method can be deployed for various mechanistic and genomic studies focusing on skeletal muscle function. ..