P R Wyde
Affiliation: Texas Medical Center
Wyde P, Chetty S, Jewell A, Schoonover S, Piedra P. Development of a cotton rat-human metapneumovirus (hMPV) model for identifying and evaluating potential hMPV antivirals and vaccines. Antiviral Res. 2005;66:57-66 pubmed
Wyde P, Stittelaar K, Osterhaus A, Guzman E, Gilbert B. Use of cotton rats for preclinical evaluation of measles vaccines. Vaccine. 2000;19:42-53 pubmed
..The results of these tests and the potential of using cotton rats as an animal model for preliminary testing of MV vaccines are discussed. ..
Wyde P, Chetty S, Jewell A, Boivin G, Piedra P. Comparison of the inhibition of human metapneumovirus and respiratory syncytial virus by ribavirin and immune serum globulin in vitro. Antiviral Res. 2003;60:51-9 pubmed
..v.IG utilized were found to have equivalent antiviral activity against hMPV and hRSV. In contrast, except for antisera specifically raised against hMPV, all of the other materials tested had marked activity only against hRSV. ..
Wyde P, Moylett E, Chetty S, Jewell A, Bowlin T, Piedra P. Comparison of the inhibition of human metapneumovirus and respiratory syncytial virus by NMSO3 in tissue culture assays. Antiviral Res. 2004;63:51-9 pubmed
..Interestingly, NMSO3, but not heparin, was able to limit secondary infection and spread of both viruses. ..