Jerry S Wolinsky

Summary

Affiliation: Texas Medical Center
Country: USA

Publications

  1. doi request reprint Magnetic resonance imaging outcomes from a phase III trial of teriflunomide
    Jerry S Wolinsky
    Department of Neurology, The University of Texas Health Science Center at Houston, USA
    Mult Scler 19:1310-9. 2013
  2. pmc Prognosis of the individual course of disease--steps in developing a decision support tool for Multiple Sclerosis
    M Daumer
    Sylvia Lawry Centre for Multiple Sclerosis Research, Munich, Germany
    BMC Med Inform Decis Mak 7:11. 2007
  3. ncbi request reprint Glatiramer acetate in primary progressive multiple sclerosis: results of a multinational, multicenter, double-blind, placebo-controlled trial
    Jerry S Wolinsky
    Department of Neurology, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA
    Ann Neurol 61:14-24. 2007
  4. ncbi request reprint Copaxone's effect on MRI-monitored disease in relapsing MS is reproducible and sustained
    J S Wolinsky
    The University of Texas Health Science Center at Houston, 6431 Fannin Street, Houston, TX 77030, USA
    Neurology 59:1284-6. 2002
  5. doi request reprint Glatiramer acetate treatment in PPMS: why males appear to respond favorably
    Jerry S Wolinsky
    The University of Texas Health Science Center at Houston, Houston, Texas 77030, USA
    J Neurol Sci 286:92-8. 2009
  6. ncbi request reprint Rational therapy for relapsing multiple sclerosis
    Jerry S Wolinsky
    Department of Neurology, The University of Texas Health Science Center at Houston, 6431 Fannin Street, Houston, Texas 77030, USA
    Lancet Neurol 2:271-2. 2003
  7. ncbi request reprint Glatiramer acetate for the treatment of multiple sclerosis
    Jerry S Wolinsky
    University of Texas Health Science Center at Houston, TX 77030, USA
    Expert Opin Pharmacother 5:875-91. 2004
  8. pmc Chronic cerebrospinal venous insufficiency: masked multimodal imaging assessment
    Staley A Brod
    Department of Neurology, University of Texas Health Science Center at Houston, USA
    Mult Scler 19:1499-507. 2013
  9. pmc Unified approach for multiple sclerosis lesion segmentation on brain MRI
    Balasrinivasa Rao Sajja
    Department of Diagnostic and Interventional Imaging, University of Texas Medical School at Houston, 6431 Fannin Street, Houston, TX 77030, USA
    Ann Biomed Eng 34:142-51. 2006
  10. doi request reprint Diffusion-tensor MR imaging of cortical lesions in multiple sclerosis: initial findings
    Aziz H Poonawalla
    Department of Diagnostic and Interventional Radiology, University of Texas Medical School at Houston, 6431 Fannin St, Houston, TX 77030, USA
    Radiology 246:880-6. 2008

Collaborators

Detail Information

Publications34

  1. doi request reprint Magnetic resonance imaging outcomes from a phase III trial of teriflunomide
    Jerry S Wolinsky
    Department of Neurology, The University of Texas Health Science Center at Houston, USA
    Mult Scler 19:1310-9. 2013
    ..The purpose of this study was to determine the effects of oral teriflunomide on multiple sclerosis (MS) pathology inferred by magnetic resonance imaging (MRI)...
  2. pmc Prognosis of the individual course of disease--steps in developing a decision support tool for Multiple Sclerosis
    M Daumer
    Sylvia Lawry Centre for Multiple Sclerosis Research, Munich, Germany
    BMC Med Inform Decis Mak 7:11. 2007
    ....
  3. ncbi request reprint Glatiramer acetate in primary progressive multiple sclerosis: results of a multinational, multicenter, double-blind, placebo-controlled trial
    Jerry S Wolinsky
    Department of Neurology, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA
    Ann Neurol 61:14-24. 2007
    ..To determine whether glatiramer acetate (GA) slows accumulation of disability in primary progressive multiple sclerosis...
  4. ncbi request reprint Copaxone's effect on MRI-monitored disease in relapsing MS is reproducible and sustained
    J S Wolinsky
    The University of Texas Health Science Center at Houston, 6431 Fannin Street, Houston, TX 77030, USA
    Neurology 59:1284-6. 2002
    ..6% reduction for those always on glatiramer acetate. Over the entire study the accumulated T2 disease burden was 34.2% less for those always on glatiramer acetate...
  5. doi request reprint Glatiramer acetate treatment in PPMS: why males appear to respond favorably
    Jerry S Wolinsky
    The University of Texas Health Science Center at Houston, Houston, Texas 77030, USA
    J Neurol Sci 286:92-8. 2009
    ..It remains reasonable to consider that there exist differences in the rates of clinical disease progression between men and women with MS that should be better studied...
  6. ncbi request reprint Rational therapy for relapsing multiple sclerosis
    Jerry S Wolinsky
    Department of Neurology, The University of Texas Health Science Center at Houston, 6431 Fannin Street, Houston, Texas 77030, USA
    Lancet Neurol 2:271-2. 2003
  7. ncbi request reprint Glatiramer acetate for the treatment of multiple sclerosis
    Jerry S Wolinsky
    University of Texas Health Science Center at Houston, TX 77030, USA
    Expert Opin Pharmacother 5:875-91. 2004
    ..The efficacy of glatiramer acetate is stable or may increase over time and the drug has a favourable side effect profile. Glatiramer acetate is an appropriate first-line immunomodulatory therapy for RR MS...
  8. pmc Chronic cerebrospinal venous insufficiency: masked multimodal imaging assessment
    Staley A Brod
    Department of Neurology, University of Texas Health Science Center at Houston, USA
    Mult Scler 19:1499-507. 2013
    ..Chronic cerebrospinal venous insufficiency (CCSVI) was implicated in the pathophysiology of multiple sclerosis (MS)...
  9. pmc Unified approach for multiple sclerosis lesion segmentation on brain MRI
    Balasrinivasa Rao Sajja
    Department of Diagnostic and Interventional Imaging, University of Texas Medical School at Houston, 6431 Fannin Street, Houston, TX 77030, USA
    Ann Biomed Eng 34:142-51. 2006
    ..The automated processing scheme detected 80% of the manually segmented lesions in the case of low lesion load and 93% of the lesions in those cases with high lesion load...
  10. doi request reprint Diffusion-tensor MR imaging of cortical lesions in multiple sclerosis: initial findings
    Aziz H Poonawalla
    Department of Diagnostic and Interventional Radiology, University of Texas Medical School at Houston, 6431 Fannin St, Houston, TX 77030, USA
    Radiology 246:880-6. 2008
    ..To prospectively perform a direct measurement of fractional anisotropy (FA) and mean diffusivity (MD) in cortical lesions of patients with multiple sclerosis (MS)...
  11. pmc Deep gray matter atrophy in multiple sclerosis: a tensor based morphometry
    Guozhi Tao
    Department of Diagnostic and Interventional Imaging, University of Texas Medical School at Houston, Houston, TX 77030, USA
    J Neurol Sci 282:39-46. 2009
    ..52, p=2.31 x 10(-7), and putamen: r=-0.66, r=2.13 x 10(-12)). More severe atrophy was observed mainly in thalamus at higher EDSS. These studies appear to suggest a link between the white matter damage and DGM atrophy in MS...
  12. pmc Randomized study combining interferon and glatiramer acetate in multiple sclerosis
    Fred D Lublin
    Corinne Goldsmith Dickinson Center for Multiple Sclerosis, Department of Neurology, and Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA
    Ann Neurol 73:327-40. 2013
    ....
  13. pmc Improved cerebellar tissue classification on magnetic resonance images of brain
    Sushmita Datta
    Department of Diagnostic and Interventional Imaging, University of Texas Medical School at Houston, Houston, Texas 77030, USA
    J Magn Reson Imaging 29:1035-42. 2009
    ..To develop and implement a method for improved cerebellar tissue classification on the MRI of brain by automatically isolating the cerebellum prior to segmentation...
  14. pmc Multimodal quantitative magnetic resonance imaging of thalamic development and aging across the human lifespan: implications to neurodegeneration in multiple sclerosis
    Khader M Hasan
    Departments of Diagnostic and Interventional Imaging, The University of Texas Health Science Center at Houston, Houston, Texas 77030, USA
    J Neurosci 31:16826-32. 2011
    ..2-69.1 years) and MS patients (N = 109, age range = 20.8-68.5 years) to demonstrate early age- and lesion-independent thalamic neurodegeneration...
  15. pmc Human brain atlas-based multimodal MRI analysis of volumetry, diffusimetry, relaxometry and lesion distribution in multiple sclerosis patients and healthy adult controls: implications for understanding the pathogenesis of multiple sclerosis and consolidat
    Khader M Hasan
    The University of Texas Health Science Center at Houston, Department of Diagnostic and Interventional Imaging, 6431 Fannin Street, MSB 2 100, Houston, Texas 77030, USA
    J Neurol Sci 313:99-109. 2012
    ..Our results support that MS at least in part has a neurodegenerative component...
  16. ncbi request reprint Segmentation of gadolinium-enhanced lesions on MRI in multiple sclerosis
    Sushmita Datta
    Department of Diagnostic and Interventional Imaging, Texas Medical School at Houston, 6431 Fannin Street, Houston, TX 77030, USA
    J Magn Reson Imaging 25:932-7. 2007
    ..To develop and implement a method for identification and quantification of gadolinium (Gd) enhancements with minimal human intervention...
  17. pmc Segmentation and quantification of black holes in multiple sclerosis
    Sushmita Datta
    Department of Diagnostic and Interventional Imaging, University of Texas Medical School at Houston, 6431 Fannin Street, Houston, 77030, USA
    Neuroimage 29:467-74. 2006
    ..Fuzzy connectivity was used for the delineation of black holes. The performance of this algorithm was quantitatively evaluated on 14 MS patients...
  18. pmc Multi-modal quantitative MRI investigation of brain tissue neurodegeneration in multiple sclerosis
    Khader M Hasan
    Department of Diagnostic and Interventional Imaging, University of Texas Health Science Center at Houston, Houston, Texas, USA
    J Magn Reson Imaging 35:1300-11. 2012
    ..To investigate the utility of multimodal quantitative MRI (qMRI) and atlas-based methods to identify characteristics of lesion-driven injury and neurodegeneration in relapsing remitting multiple sclerosis (RRMS)...
  19. pmc Intracortical lesions by 3T magnetic resonance imaging and correlation with cognitive impairment in multiple sclerosis
    Flavia Nelson
    Department of Neurology, University of Texas Houston, Health Science Center, Houston, Texas, USA
    Mult Scler 17:1122-9. 2011
    ....
  20. pmc Caudate nuclei volume, diffusion tensor metrics, and T(2) relaxation in healthy adults and relapsing-remitting multiple sclerosis patients: implications for understanding gray matter degeneration
    Khader M Hasan
    Department of Diagnostic and Interventional Imaging, University of Texas Health Science Center at Houston, Houston, Texas, USA
    J Magn Reson Imaging 29:70-7. 2009
    ..To investigate the utility of caudate nuclei (CN) macro- and microstructural metrics as markers of gray matter degeneration in healthy adults and relapsing-remitting multiple sclerosis (RRMS) patients...
  21. ncbi request reprint The PROMiSe trial: baseline data review and progress report
    Jerry S Wolinsky
    University of Texas Health Science Center at Houston, 6431 Fannin Street, Houston, TX 77030, USA
    Mult Scler 10:S65-71; discussion S71-2. 2004
    ..These early findings raise some concern about the ability of the trial to demonstrate a significant treatment effect, and suggest that the short-term natural history of PPMS may not be as aggressive as previously assumed...
  22. ncbi request reprint Multicentre proton magnetic resonance spectroscopy imaging of primary progressive multiple sclerosis
    Ponnada A Narayana
    Department of Radiology, University of Texas Houston Medical School, 6431 Fannin, Room 6 172, Houston, TX 77030, USA
    Mult Scler 10:S73-8. 2004
    ..No significant correlation between any of the metabolite ratios and the Extended Disability Scale Score (EDSS) or with other MR measures such as lesion burden and enhancement volumes is observed...
  23. ncbi request reprint Diffusion tensor fractional anisotropy of the normal-appearing seven segments of the corpus callosum in healthy adults and relapsing-remitting multiple sclerosis patients
    Khader M Hasan
    Department of Interventional and Diagnostic Imaging, University of Texas Medical School at Houston, Houston, Texas, USA
    J Magn Reson Imaging 21:735-43. 2005
    ....
  24. ncbi request reprint The use of glatiramer acetate in the treatment of multiple sclerosis
    Jerry S Wolinsky
    University of Texas Health Science Center at Houston, USA
    Adv Neurol 98:273-92. 2006
    ..Supportive data from open-label comparison, combination treatment and therapeutic switch studies are also provided to enable informed decisions on the appropriate place for GA among other immunomodulatory treatments for relapsing MS...
  25. pmc Chronic cerebrospinal venous insufficiency: case-control neurosonography results
    Andrew D Barreto
    Departments of Neurology, University of Texas Health Science Center at Houston, Houston, TX 77030, USA
    Ann Neurol 73:721-8. 2013
    ..We sought to determine whether neurosonography (NS) provides reliable information on cerebral venous outflow patterns specific to MS...
  26. ncbi request reprint The diagnosis of primary progressive multiple sclerosis
    Jerry S Wolinsky
    Department of Neurology, The University of Texas Health Science Center at Houston, 6431 Fannin Street, Houston, TX 77030, USA
    J Neurol Sci 206:145-52. 2003
    ....
  27. pmc Multi-task functional MRI in multiple sclerosis patients without clinical disability
    Rene A Colorado
    Department of Diagnostic and Interventional Imaging, University of Texas Medical School at Houston, Houston, Texas 77030, USA
    Neuroimage 59:573-81. 2012
    ....
  28. ncbi request reprint Magnetic resonance spectroscopy in multiple sclerosis: window into the diseased brain
    Jerry S Wolinsky
    Department of Neurology, The University of Texas Health Science Center at Houston, 6431 Fannin Street, Houston, TX 77030, USA
    Curr Opin Neurol 15:247-51. 2002
    ....
  29. ncbi request reprint Effects of oral glatiramer acetate on clinical and MRI-monitored disease activity in patients with relapsing multiple sclerosis: a multicentre, double-blind, randomised, placebo-controlled study
    Massimo Filippi
    Neuroimaging Research Unit, Institute of Experimental Neurology and University Ospedale San Raffaele, Milan, Italy
    Lancet Neurol 5:213-20. 2006
    ..This study assessed whether two doses of glatiramer acetate given orally could improve clinical and MRI measures of inflammation and neurodegeneration in a large cohort of patients with relapsing-remitting multiple sclerosis...
  30. ncbi request reprint Short-term correlations between clinical and MR imaging findings in relapsing-remitting multiple sclerosis
    Marco Rovaris
    Neuroimaging Research Unit, Department of Neuroscience, Scientific Institute and University Ospedale San Raffaele, Milan, Italy
    AJNR Am J Neuroradiol 24:75-81. 2003
    ..Using data from the European/Canadian glatiramer acetate (GA) trial, we investigated short-term correlations between clinical and MR measures of disease activity in patients with relapsing-remitting MS (RRMS)...
  31. ncbi request reprint Effects of glatiramer acetate on relapse rate and accumulated disability in multiple sclerosis: meta-analysis of three double-blind, randomized, placebo-controlled clinical trials
    Filippo Martinelli Boneschi
    Department of Neuroscience, Scientific Institute, University H San Raffaele, Milan, Italy
    Mult Scler 9:349-55. 2003
    ..It also suggests that GA efficacy is not significantly influenced by the patients' clinical characteristics at the time of treatment initiation...
  32. ncbi request reprint Magnetic resonance techniques for the in vivo assessment of multiple sclerosis pathology: consensus report of the white matter study group
    Massimo Filippi
    Neuroimaging Research Unit, Department of Neurology, Scientific Institute and University Ospedale San Raffaele, Milan, Italy
    J Magn Reson Imaging 21:669-75. 2005
    ..Both of these steps are central to the design of future treatment strategies aimed at limiting the functional consequences of the most disabling aspects of this disease...
  33. pmc Imaging of multiple sclerosis: role in neurotherapeutics
    Rohit Bakshi
    Department of Neurology and Radiology, Partners MS Center, Center for Neurological Imaging, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    NeuroRx 2:277-303. 2005
    ..However, these advanced methods are limited by their cost, availability, complexity, and lack of validation. In this article, we review the role of conventional and advanced imaging techniques with an emphasis on neurotherapeutics...
  34. ncbi request reprint Interferon-beta antibodies: implications for the treatment of MS
    Jerry S Wolinsky
    Lancet Neurol 2:528. 2003