S C Williams

Summary

Affiliation: Texas Tech University Health Sciences Center
Country: USA

Publications

  1. ncbi C/EBPepsilon is a myeloid-specific activator of cytokine, chemokine, and macrophage-colony-stimulating factor receptor genes
    S C Williams
    Department of Cell Biology and Biochemistry, Texas Tech University Health Sciences Center, Lubbock, Texas 79430, USA
    J Biol Chem 273:13493-501. 1998
  2. ncbi Peroxisome proliferator-activated receptor gamma and chicken ovalbumin upstream promoter transcription factor II negatively regulate the phosphoenolpyruvate carboxykinase promoter via a common element
    D W Eubank
    Department of Cell Biology and Biochemistry, Texas Tech University Health Sciences Center, Lubbock, Texas 79430, USA
    J Biol Chem 276:30561-9. 2001
  3. ncbi C/EBPbeta interacts with the P-enolpyruvate carboxykinase adipocyte-specific enhancer
    D W Eubank
    Department of Cell Biology and Biochemistry, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA
    Biochem Biophys Res Commun 285:811-9. 2001
  4. ncbi Elements involved in the regulation of the StAR gene
    D M Stocco
    Department of Cell Biology and Biochemistry, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA
    Mol Cell Endocrinol 177:55-9. 2001
  5. ncbi C/EBP proteins contain nuclear localization signals imbedded in their basic regions
    S C Williams
    Department of Cell Biology and Biochemistry, Texas Tech University Health Sciences Center, Lubbock 79430, USA
    Gene Expr 6:371-85. 1997
  6. ncbi SF-1 (steroidogenic factor-1) and C/EBP beta (CCAAT/enhancer binding protein-beta) cooperate to regulate the murine StAR (steroidogenic acute regulatory) promoter
    A J Reinhart
    Department of Cell Biology and Biochemistry, Texas Tech University Health Science Center Lubbock 79430, USA
    Mol Endocrinol 13:729-41. 1999
  7. ncbi Identification of an interleukin-3-regulated aldoketo reductase gene in myeloid cells which may function in autocrine regulation of myelopoiesis
    Y Du
    Department of Cell Biology and Biochemistry, Texas Tech University Health Sciences Center, Lubbock, Texas 79430, USA
    J Biol Chem 275:6724-32. 2000
  8. ncbi Pseudomonas aeruginosa autoinducer modulates host cell responses through calcium signalling
    E K Shiner
    Department of Microbiology and Immunology, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA
    Cell Microbiol 8:1601-10. 2006
  9. ncbi A highly conserved lens transcriptional control element from the Pax-6 gene
    S C Williams
    Skirball Institute for Biomolecular Medicine, Developmental Genetics Program, Cell Biology and Pathology Departments, New York University Medical Center, 540 First Avenue, New York, NY 10016, USA
    Mech Dev 73:225-9. 1998
  10. ncbi Mouse chromosomal location of the CCAAT/enhancer binding proteins C/EBP beta (Cebpb), C/EBP delta (Cebpd), and CRP1 (Cebpe)
    N A Jenkins
    ABL Basic Research Program, NCI Frederick Cancer Research and Development Center, Maryland 21702 1201, USA
    Genomics 28:333-6. 1995

Collaborators

  • D M Stocco
  • B J Clark
  • G Li
  • R Martinez-Zaguilan
  • X J Wang
  • T Sakurai
  • N A Elshourbagy
  • D W Eubank
  • E K Shiner
  • E G Beale
  • Y Du
  • A J Reinhart
  • K P Rumbaugh
  • D Terentyev
  • S Gyorke
  • S Sennoune
  • D E Clouthier
  • A Bryan
  • P F Johnson
  • C Forest
  • E Duplus
  • J R Keller
  • S Tsai
  • N A Jenkins
  • J D Bretz
  • M Kumada
  • T Kuwaki
  • J A Richardson
  • H Yanagisawa
  • K Hosoda
  • R E Hammer
  • A J Lincoln
  • M Yanagisawa
  • B C Cho
  • N G Copeland
  • M C Strobel
  • D J Gilbert
  • R C Schwartz
  • M Baer

Detail Information

Publications17

  1. ncbi C/EBPepsilon is a myeloid-specific activator of cytokine, chemokine, and macrophage-colony-stimulating factor receptor genes
    S C Williams
    Department of Cell Biology and Biochemistry, Texas Tech University Health Sciences Center, Lubbock, Texas 79430, USA
    J Biol Chem 273:13493-501. 1998
    ..These results suggest that C/EBPepsilon may be an important regulator of differentiation of a subset of myeloid cell types and may also participate in the regulation of cytokine gene expression in mature cells...
  2. ncbi Peroxisome proliferator-activated receptor gamma and chicken ovalbumin upstream promoter transcription factor II negatively regulate the phosphoenolpyruvate carboxykinase promoter via a common element
    D W Eubank
    Department of Cell Biology and Biochemistry, Texas Tech University Health Sciences Center, Lubbock, Texas 79430, USA
    J Biol Chem 276:30561-9. 2001
    ....
  3. ncbi C/EBPbeta interacts with the P-enolpyruvate carboxykinase adipocyte-specific enhancer
    D W Eubank
    Department of Cell Biology and Biochemistry, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA
    Biochem Biophys Res Commun 285:811-9. 2001
    ..However, mutation of all three elements did not affect reporter transactivation by C/EBPbeta suggesting that additional elements participate in PEPCK regulation or that the effects of C/EBPbeta are indirect...
  4. ncbi Elements involved in the regulation of the StAR gene
    D M Stocco
    Department of Cell Biology and Biochemistry, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA
    Mol Cell Endocrinol 177:55-9. 2001
    ..This short review will summarize some of the findings that have been reported concerning the nature of how the expression of this gene is regulated...
  5. ncbi C/EBP proteins contain nuclear localization signals imbedded in their basic regions
    S C Williams
    Department of Cell Biology and Biochemistry, Texas Tech University Health Sciences Center, Lubbock 79430, USA
    Gene Expr 6:371-85. 1997
    ..Finally, we observed that a C/EBPbeta protein lacking its NLS can be localized to the nucleus when coexpressed with C/EBPalpha, indicating that a single NLS is sufficient to promote nuclear transport of a bZIP dimer...
  6. ncbi SF-1 (steroidogenic factor-1) and C/EBP beta (CCAAT/enhancer binding protein-beta) cooperate to regulate the murine StAR (steroidogenic acute regulatory) promoter
    A J Reinhart
    Department of Cell Biology and Biochemistry, Texas Tech University Health Science Center Lubbock 79430, USA
    Mol Endocrinol 13:729-41. 1999
    ..These data indicate that in addition to SF-1, C/EBP beta is involved in the transcriptional regulation of the StAR gene and may play an important role in developmental and hormone-responsive regulation of steroidogenesis...
  7. ncbi Identification of an interleukin-3-regulated aldoketo reductase gene in myeloid cells which may function in autocrine regulation of myelopoiesis
    Y Du
    Department of Cell Biology and Biochemistry, Texas Tech University Health Sciences Center, Lubbock, Texas 79430, USA
    J Biol Chem 275:6724-32. 2000
    ..We propose that mAKRa may catalyze the production or catabolism of autocrine factors that promote the proliferation and/or lineage commitment of early myeloid progenitors...
  8. ncbi Pseudomonas aeruginosa autoinducer modulates host cell responses through calcium signalling
    E K Shiner
    Department of Microbiology and Immunology, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA
    Cell Microbiol 8:1601-10. 2006
    ....
  9. ncbi A highly conserved lens transcriptional control element from the Pax-6 gene
    S C Williams
    Skirball Institute for Biomolecular Medicine, Developmental Genetics Program, Cell Biology and Pathology Departments, New York University Medical Center, 540 First Avenue, New York, NY 10016, USA
    Mech Dev 73:225-9. 1998
    ..This element will provide an important tool in future transgenic analyses of lens formation and will allow identification of transcription factors with a central function in lens development...
  10. ncbi Mouse chromosomal location of the CCAAT/enhancer binding proteins C/EBP beta (Cebpb), C/EBP delta (Cebpd), and CRP1 (Cebpe)
    N A Jenkins
    ABL Basic Research Program, NCI Frederick Cancer Research and Development Center, Maryland 21702 1201, USA
    Genomics 28:333-6. 1995
    ..Here, we show that Cebpb maps to mouse chromosome 2, Cebpd to chromosome 16, and Cebpe to chromosome 14. The assignment of Cebpd to chromosome 16 identifies a new region of homology between mouse chromosome 16 and human chromosome 8...
  11. pmc C/EBP-related protein 2 confers lipopolysaccharide-inducible expression of interleukin 6 and monocyte chemoattractant protein 1 to a lymphoblastic cell line
    J D Bretz
    Department of Microbiology, Michigan State University, East Lansing 48824 1101
    Proc Natl Acad Sci U S A 91:7306-10. 1994
    ..This work clearly establishes the essential role of CRP2 in the induction of cytokine genes by LPS. Additionally, these data add MCP-1 to the list of cytokines showing an involvement of CRP2 in their expression...
  12. ncbi A revised sequence of the rat c/ebp gene
    A J Lincoln
    ABL Basic Research Program, National Cancer Institute Frederick Cancer Research and Development Center, Maryland 21702 1201
    Genes Dev 8:1131-2. 1994
  13. ncbi A family of C/EBP-related proteins capable of forming covalently linked leucine zipper dimers in vitro
    S C Williams
    ABL Basic Research Program, National Cancer Institute Frederick Cancer Research and Development Center, Maryland 21702 1201
    Genes Dev 5:1553-67. 1991
    ..Our findings indicate that a set of potentially interacting C/EBP-like proteins exists, whose complexity is comparable to that of other bZIP protein subfamilies such as Jun, Fos, and ATF/CREB...
  14. ncbi Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior
    T Sakurai
    Howard Hughes Medical Institute, Department of Molecular Genetics, University of Texas Southwestern Medical Center at Dallas, 75235 9050, USA
    Cell 92:573-85. 1998
    ..prepro-orexin mRNA level is up-regulated upon fasting, suggesting a physiological role for the peptides as mediators in the central feedback mechanism that regulates feeding behavior...
  15. ncbi Cranial and cardiac neural crest defects in endothelin-A receptor-deficient mice
    D E Clouthier
    Howard Hughes Medical Institute, Department of Molecular Genetics, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75235, USA
    Development 125:813-24. 1998
    ..These observations define a novel genetic pathway for inductive communication between cephalic neural crest cells and their environmental counterparts...
  16. ncbi Sequence and evolution of the human germline V lambda repertoire
    S C Williams
    MRC Centre for Protein Engineering Hills Road, Cambridge, UK
    J Mol Biol 264:220-32. 1996
    ..V lambda genes related to the major human V lambda families (V lambda 1, V lambda 2 and V lambda 3) predominate in species that express mainly lambda light chains...
  17. pmc Mouse apolipoprotein A-IV gene: nucleotide sequence and induction by a high-lipid diet
    S C Williams
    Mol Cell Biol 6:3807-14. 1986
    ..We also show that chronically high dietary lipid induces liver apo A-IV levels 10-fold in C57BL/6 mice, a strain susceptible to atherosclerotic lesions, while we observed no induction in nonsusceptible BALB/c and C3H mice...