VERNON R SUTTON

Summary

Affiliation: Texas Medical Center
Country: USA

Publications

  1. ncbi request reprint Search for imprinted regions on chromosome 14: comparison of maternal and paternal UPD cases with cases of chromosome 14 deletion
    V R Sutton
    Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, USA
    Am J Med Genet 93:381-7. 2000
  2. ncbi request reprint Tay-Sachs disease screening and counseling families at risk for metabolic disease
    V Reid Sutton
    Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA
    Obstet Gynecol Clin North Am 29:287-96. 2002
  3. ncbi request reprint 3-Hydroxy-2-methylbutyryl-CoA dehydrogenase deficiency
    V R Sutton
    Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, USA
    J Inherit Metab Dis 26:69-71. 2003
  4. ncbi request reprint Skeletal defects in paternal uniparental disomy for chromosome 14 are re-capitulated in the mouse model (paternal uniparental disomy 12)
    V Reid Sutton
    Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, USA
    Hum Genet 113:447-51. 2003
  5. ncbi request reprint A dominantly inherited spondylometaphyseal dysplasia with "corner fractures" and congenital scoliosis
    V Reid Sutton
    Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030 3498, USA
    Am J Med Genet A 133:209-12. 2005
  6. doi request reprint Microduplications of 22q11.2 are frequently inherited and are associated with variable phenotypes
    Zhishuo Ou
    Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA
    Genet Med 10:267-77. 2008
  7. ncbi request reprint Subtelomeric FISH uncovers trisomy 14q32: lessons for imprinted regions, cryptic rearrangements and variant acrocentric short arms
    V Reid Sutton
    Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA
    Am J Med Genet 112:23-7. 2002
  8. ncbi request reprint Microarray-based CGH detects chromosomal mosaicism not revealed by conventional cytogenetics
    Sau W Cheung
    Department of Human and Molecular Genetics, Baylor College of Medicine, Houston, Texas 77030
    Am J Med Genet A 143:1679-86. 2007
  9. pmc Assessing sex assignment concordance with genotype and phenotype
    Deepa Suresh
    Department of OBGYN, Division of Pediatric and Adolescent Gynecology, Baylor College of Medicine, Houston, TX, 77030, USA
    Int J Pediatr Endocrinol 2013:7. 2013
  10. ncbi request reprint Ethical and legal implications of genetic testing in androgen insensitivity syndrome
    Jonathan S Berg
    Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA
    J Pediatr 150:434-8. 2007

Research Grants

Collaborators

Detail Information

Publications22

  1. ncbi request reprint Search for imprinted regions on chromosome 14: comparison of maternal and paternal UPD cases with cases of chromosome 14 deletion
    V R Sutton
    Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, USA
    Am J Med Genet 93:381-7. 2000
    ....
  2. ncbi request reprint Tay-Sachs disease screening and counseling families at risk for metabolic disease
    V Reid Sutton
    Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA
    Obstet Gynecol Clin North Am 29:287-96. 2002
    ..Options to modify this risk include prenatal diagnosis by amniocentesis or chorionic villus sampling, egg or sperm donation, preimplantation diagnosis or adoption...
  3. ncbi request reprint 3-Hydroxy-2-methylbutyryl-CoA dehydrogenase deficiency
    V R Sutton
    Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, USA
    J Inherit Metab Dis 26:69-71. 2003
    ..Urine organic acid analysis revealed 3-hydroxy-2-methylbutyric acid and tiglyglycine; 3-ketothiolase enzyme activity was normal and he was subsequently found to have 3-hydroxy-2-methylbutyryl-CoA dehydrogenase deficiency...
  4. ncbi request reprint Skeletal defects in paternal uniparental disomy for chromosome 14 are re-capitulated in the mouse model (paternal uniparental disomy 12)
    V Reid Sutton
    Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, USA
    Hum Genet 113:447-51. 2003
    ....
  5. ncbi request reprint A dominantly inherited spondylometaphyseal dysplasia with "corner fractures" and congenital scoliosis
    V Reid Sutton
    Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030 3498, USA
    Am J Med Genet A 133:209-12. 2005
    ....
  6. doi request reprint Microduplications of 22q11.2 are frequently inherited and are associated with variable phenotypes
    Zhishuo Ou
    Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA
    Genet Med 10:267-77. 2008
    ..To date, only a small number of patients with 22q11.2 microduplication have been identified...
  7. ncbi request reprint Subtelomeric FISH uncovers trisomy 14q32: lessons for imprinted regions, cryptic rearrangements and variant acrocentric short arms
    V Reid Sutton
    Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA
    Am J Med Genet 112:23-7. 2002
    ....
  8. ncbi request reprint Microarray-based CGH detects chromosomal mosaicism not revealed by conventional cytogenetics
    Sau W Cheung
    Department of Human and Molecular Genetics, Baylor College of Medicine, Houston, Texas 77030
    Am J Med Genet A 143:1679-86. 2007
    ..This suggests that aCGH may detect somatic chromosomal mosaicism that would be missed by conventional cytogenetics...
  9. pmc Assessing sex assignment concordance with genotype and phenotype
    Deepa Suresh
    Department of OBGYN, Division of Pediatric and Adolescent Gynecology, Baylor College of Medicine, Houston, TX, 77030, USA
    Int J Pediatr Endocrinol 2013:7. 2013
    ....
  10. ncbi request reprint Ethical and legal implications of genetic testing in androgen insensitivity syndrome
    Jonathan S Berg
    Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA
    J Pediatr 150:434-8. 2007
  11. doi request reprint Duplication of chromosome band 12q24.11q24.23 results in apparent Noonan syndrome
    Oleg A Shchelochkov
    Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, USA
    Am J Med Genet A 146:1042-8. 2008
    ....
  12. doi request reprint Cranio-meta-diaphyseal dysplasia: 25 year follow-up and review of literature
    Shweta U Dhar
    Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA
    Am J Med Genet A 152:2335-8. 2010
    ..He is the oldest reported patient with this disorder giving some insight into the natural history of this rare skeletal dysplasia...
  13. doi request reprint Low-level mosaicism of trisomy 14: phenotypic and molecular characterization
    Marwan Shinawi
    Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA
    Am J Med Genet A 146:1395-405. 2008
    ....
  14. ncbi request reprint Chromosomal microarray analysis (CMA) detects a large X chromosome deletion including FMR1, FMR2, and IDS in a female patient with mental retardation
    Frank J Probst
    Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA
    Am J Med Genet A 143:1358-65. 2007
    ..This case demonstrates the utility of CMA both for detecting a submicroscopic chromosomal deletion and for suggesting further testing that could possibly lead to therapeutic options for patients with developmental delay...
  15. doi request reprint Management of ornithine transcarbamylase deficiency in pregnancy
    Hector Mendez-Figueroa
    Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, Baylor College of Medicine, Houston, TX 77030, USA
    Am J Perinatol 27:775-84. 2010
    ..A comprehensive plan for patients who develop hyperammonemia is recommended...
  16. pmc 22q11.2 distal deletion: a recurrent genomic disorder distinct from DiGeorge syndrome and velocardiofacial syndrome
    Shay Ben-Shachar
    Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA
    Am J Hum Genet 82:214-21. 2008
    ..2 between LCR22-4 and LCR22-6, although they share some characteristic features with DGS/VCFS, represent a novel genomic disorder distinct genomically and clinically from the well-known DGS/VCF deletion syndromes...
  17. ncbi request reprint Low or absent unconjugated estriol in pregnancy: an indicator for steroid sulfatase deficiency detectable by fluorescence in situ hybridization and biochemical analysis
    Catherine D Kashork
    Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA
    Prenat Diagn 22:1028-32. 2002
    ..Postnatal FISH confirmation of the STS deletion was performed in 1/7 cases. Clinical follow-up was available for 4/9 cases following birth...
  18. ncbi request reprint Newborn screening and prenatal diagnosis for Rett syndrome: implications for therapy
    Ruthie E Amir
    Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, TX 77030, USA
    J Child Neurol 20:779-83. 2005
    ..In contrast, prenatal diagnosis should be offered to the parents of an affected child if the responsible mutation has been identified in the index case...
  19. doi request reprint Craniofacial and anthropometric phenotype in ankyloblepharon-ectodermal defects-cleft lip/palate syndrome (Hay-Wells syndrome) in a cohort of 17 patients
    V Reid Sutton
    Department of Molecular and Human Genetics, Baylor College of Medicine, Texas Children s Hospital, 6621 Fannin Street, Houston, TX 77030, USA
    Am J Med Genet A 149:1916-21. 2009
    ..In addition, we describe the frequency of phenotypic features and demonstrate the extreme clinical variability in the largest cohort of AEC individuals reported in the literature thus far...
  20. pmc A genome-wide screen for copy number alterations in Aicardi syndrome
    Xiaoling Wang
    Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, Texas 77030, USA
    Am J Med Genet A 149:2113-21. 2009
    ..We conclude that, in this study population of 38 subjects, Aicardi syndrome is not caused by CNVs detectable with the high-resolution array platform that was used...
  21. pmc Clinical spectrum associated with recurrent genomic rearrangements in chromosome 17q12
    Sandesh Chakravarthy Sreenath Nagamani
    Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA
    Eur J Hum Genet 18:278-84. 2010
    ..Our findings expand the phenotypic spectrum associated with rearrangements of 17q12 and show that cognitive impairment is a part of the phenotype of individuals with deletions of 17q12...
  22. pmc Neuroimaging aspects of Aicardi syndrome
    Bobbi Hopkins
    Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA
    Am J Med Genet A 146:2871-8. 2008
    ..We further propose that improved characterization of the neurological phenotype will benefit the selection of candidate genes for mutation analysis...

Research Grants1

  1. Clinical Phenotype of Imprinted Genes of Chromosome 14
    Vernon Sutton; Fiscal Year: 2005
    ..This phenotype delineation will lay the foundation for understanding the effects and pathogenesis of imprinted genes on chromosome 14. ..