AGNETA LISBETH SUNEHAG

Summary

Affiliation: Texas Medical Center
Country: USA

Publications

  1. ncbi request reprint Short-term high dietary fructose intake had no effects on insulin sensitivity and secretion or glucose and lipid metabolism in healthy, obese adolescents
    Agneta L Sunehag
    Baylor College of Medicine, Children s Nutrition Research Center, Houston, TX 77030, USA
    J Pediatr Endocrinol Metab 21:225-35. 2008
  2. doi request reprint Effect of ghrelin on glucose regulation in mice
    Shaji K Chacko
    Department of Pediatrics, Baylor College of Medicine Children s Nutrition Research Center, United States Department of Agriculture Agricultural Research Service, Houston, TX, USA
    Am J Physiol Endocrinol Metab 302:E1055-62. 2012
  3. ncbi request reprint Gluconeogenesis in very low birth weight infants receiving total parenteral nutrition
    A L Sunehag
    US Department of Agriculture Agricultural Research Service Children s Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, Texas 77030, USA
    Diabetes 48:791-800. 1999
  4. ncbi request reprint Effects of dietary macronutrient intake on insulin sensitivity and secretion and glucose and lipid metabolism in healthy, obese adolescents
    Agneta L Sunehag
    Baylor College of Medicine, Children s Nutrition Research Center, 1100 Bates Street, Houston, Texas 77030, USA
    J Clin Endocrinol Metab 90:4496-502. 2005
  5. ncbi request reprint The role of parenteral lipids in supporting gluconeogenesis in very premature infants
    Agneta L Sunehag
    Children s Nutrition Research Center, USDA ARS, Baylor College of Medicine, Houston, TX 77030, USA
    Pediatr Res 54:480-6. 2003
  6. ncbi request reprint Parenteral glycerol enhances gluconeogenesis in very premature infants
    Agneta L Sunehag
    Children s Nutrition Research Center, USDA ARS, Baylor College of Medicine, Houston, Texas 77030, USA
    Pediatr Res 53:635-41. 2003
  7. ncbi request reprint Effects of dietary macronutrient content on glucose metabolism in children
    Agneta L Sunehag
    Children s Nutrition Research Center, USDA Agricultural Research Service, 1100 Bates Street, Houston, TX 77030, USA
    J Clin Endocrinol Metab 87:5168-78. 2002
  8. ncbi request reprint Glucose extremes in newborn infants
    Agneta L Sunehag
    Children s Nutrition Research Center, USDA ARS, Baylor College of Medicine, Houston, TX 77030, USA
    Clin Perinatol 29:245-60. 2002
  9. pmc Mechanisms to conserve glucose in lactating women during a 42-h fast
    Mahmoud A Mohammad
    Children s Nutrition Research Center, Baylor College of Medicine, Houston, TX 77030 2600, USA
    Am J Physiol Endocrinol Metab 297:E879-88. 2009
  10. pmc Effect of dietary macronutrient composition under moderate hypocaloric intake on maternal adaptation during lactation
    Mahmoud A Mohammad
    Department of Pediatrics, Children s Nutrition Research Center, US Department of Agriculture, Agricultural Research Service, Baylor College of Medicine, Houston, TX 77030 2600, USA
    Am J Clin Nutr 89:1821-7. 2009

Collaborators

Detail Information

Publications27

  1. ncbi request reprint Short-term high dietary fructose intake had no effects on insulin sensitivity and secretion or glucose and lipid metabolism in healthy, obese adolescents
    Agneta L Sunehag
    Baylor College of Medicine, Children s Nutrition Research Center, Houston, TX 77030, USA
    J Pediatr Endocrinol Metab 21:225-35. 2008
    ..There is virtually no information on the metabolic impact of dietary fructose intake in adolescents despite their high fructose consumption, particularly via sweetened beverages...
  2. doi request reprint Effect of ghrelin on glucose regulation in mice
    Shaji K Chacko
    Department of Pediatrics, Baylor College of Medicine Children s Nutrition Research Center, United States Department of Agriculture Agricultural Research Service, Houston, TX, USA
    Am J Physiol Endocrinol Metab 302:E1055-62. 2012
    ..This study demonstrates that gluconeogenesis and glycogenolysis are increased and insulin sensitivity is improved by the ablation of the ghrelin or growth hormone secretagogue receptor in mice...
  3. ncbi request reprint Gluconeogenesis in very low birth weight infants receiving total parenteral nutrition
    A L Sunehag
    US Department of Agriculture Agricultural Research Service Children s Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, Texas 77030, USA
    Diabetes 48:791-800. 1999
    ..We conclude that in VLBW infants receiving TPN, normoglycemia was maintained during reduced glucose infusion by glucose production primarily derived from gluconeogenesis, and that glycerol was the principal gluconeogenic substrate...
  4. ncbi request reprint Effects of dietary macronutrient intake on insulin sensitivity and secretion and glucose and lipid metabolism in healthy, obese adolescents
    Agneta L Sunehag
    Baylor College of Medicine, Children s Nutrition Research Center, 1100 Bates Street, Houston, Texas 77030, USA
    J Clin Endocrinol Metab 90:4496-502. 2005
    ..Adolescent obesity is a serious public health concern...
  5. ncbi request reprint The role of parenteral lipids in supporting gluconeogenesis in very premature infants
    Agneta L Sunehag
    Children s Nutrition Research Center, USDA ARS, Baylor College of Medicine, Houston, TX 77030, USA
    Pediatr Res 54:480-6. 2003
    ..4 +/- 0.6 vs. 4.9 +/- 0.7 micromol/kg min (g+ IL and g + AA + IL groups, respectively). In conclusion, in parenterally fed very premature infants, lipids play a primary role in supporting gluconeogenesis...
  6. ncbi request reprint Parenteral glycerol enhances gluconeogenesis in very premature infants
    Agneta L Sunehag
    Children s Nutrition Research Center, USDA ARS, Baylor College of Medicine, Houston, Texas 77030, USA
    Pediatr Res 53:635-41. 2003
    ..3 +/- 0.2 to 6.3 +/- 0.5 (p < 0.03), and 6.0 +/- 0.7 to 8.8 +/- 0.8 micromol/kg/min (p < 0.01). In very premature infants, parenteral glycerol enhances gluconeogenesis and attenuates time dependent decrease in glucose production...
  7. ncbi request reprint Effects of dietary macronutrient content on glucose metabolism in children
    Agneta L Sunehag
    Children s Nutrition Research Center, USDA Agricultural Research Service, 1100 Bates Street, Houston, TX 77030, USA
    J Clin Endocrinol Metab 87:5168-78. 2002
    ..In the adolescents, the high carbohydrate diet resulted in increased insulin sensitivity, thus facilitating insulin-mediated glucose uptake...
  8. ncbi request reprint Glucose extremes in newborn infants
    Agneta L Sunehag
    Children s Nutrition Research Center, USDA ARS, Baylor College of Medicine, Houston, TX 77030, USA
    Clin Perinatol 29:245-60. 2002
  9. pmc Mechanisms to conserve glucose in lactating women during a 42-h fast
    Mahmoud A Mohammad
    Children s Nutrition Research Center, Baylor College of Medicine, Houston, TX 77030 2600, USA
    Am J Physiol Endocrinol Metab 297:E879-88. 2009
    ..The extra glucose demands of extended fasting during lactation appear to be compensated by increasing gluconeogenesis associated with ketosis, decreasing carbohydrate oxidation, and increasing protein and FFA oxidations...
  10. pmc Effect of dietary macronutrient composition under moderate hypocaloric intake on maternal adaptation during lactation
    Mahmoud A Mohammad
    Department of Pediatrics, Children s Nutrition Research Center, US Department of Agriculture, Agricultural Research Service, Baylor College of Medicine, Houston, TX 77030 2600, USA
    Am J Clin Nutr 89:1821-7. 2009
    ..No evidence-based recommendations exist concerning what dietary macronutrient composition optimizes weight loss during lactation while maintaining milk production...
  11. ncbi request reprint Metabolic adaptation to high-fat and high-carbohydrate diets in children and adolescents
    Margarita S Treuth
    US Department of Agriculture Agricultural Research Service Children s Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine and Texas Children s Hospital, Houston 77030, USA
    Am J Clin Nutr 77:479-89. 2003
    ..Difficulty adapting to high-fat (HF) and high carbohydrate (HC) diets may predispose children to obesity and diabetes...
  12. doi request reprint Gluconeogenesis continues in premature infants receiving total parenteral nutrition
    Shaji K Chacko
    Department of Pediatrics, Baylor College of Medicine, Houston, Texas 77030, USA
    Arch Dis Child Fetal Neonatal Ed 95:F413-8. 2010
    ..To determine the contribution of total gluconeogenesis to glucose production in preterm infants receiving total parenteral nutrition (TPN) providing glucose exceeding normal infant glucose turnover rates...
  13. doi request reprint Measurement of gluconeogenesis using glucose fragments and mass spectrometry after ingestion of deuterium oxide
    Shaji K Chacko
    USDA ARS Children s Nutrition Research Center, 1100 Bates St, Houston, TX 77030 2600, USA
    J Appl Physiol 104:944-51. 2008
    ....
  14. ncbi request reprint Dietary glutamate is almost entirely removed in its first pass through the splanchnic bed in premature infants
    Stephane P Hays
    Children s Nutrition Research Center, USDA ARS, Baylor College of Medicine, Houston, Texas 77030, USA
    Pediatr Res 62:353-6. 2007
    ..Thus, in premature infants, splanchnic extraction is the major fate of dietary glutamate, which is not a significant gluconeogenic substrate in these infants...
  15. pmc Aerobic exercise increases peripheral and hepatic insulin sensitivity in sedentary adolescents
    Gert Jan van der Heijden
    Department of Pediatrics G J v d H, A L S, Baylor College of Medicine, Houston, Texas 77030, USA
    J Clin Endocrinol Metab 94:4292-9. 2009
    ..Data are limited on the effects of controlled aerobic exercise programs (without weight loss) on insulin sensitivity and glucose metabolism in children and adolescents...
  16. ncbi request reprint Metabolic adaptations in the absence of perilipin: increased beta-oxidation and decreased hepatic glucose production associated with peripheral insulin resistance but normal glucose tolerance in perilipin-null mice
    Pradip K Saha
    Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA
    J Biol Chem 279:35150-8. 2004
    ..These experiments uncover the metabolic adaptations associated with the constitutional lipolysis in plin(-/-) mice that allowed the mice to continue to exhibit normal glucose tolerance in the presence of peripheral insulin resistance...
  17. ncbi request reprint Impact of duration of infusion and choice of isotope label on isotope recycling in glucose homeostasis
    Stelios K Tigas
    Baylor College of Medicine, Children s Nutrition Research Center, USDA ARS, Department of Pediatrics Nutrition, Houston, Texas 77030, USA
    Diabetes 51:3170-5. 2002
    ..These studies demonstrate that the duration of isotope infusion has significantly greater impact on quantitation of glucose R(a) than does the selection of isotope...
  18. doi request reprint beta-Cell function and insulin sensitivity in adolescents from an OGTT
    Agneta L Sunehag
    Children Nutrition s Research Center, Baylor College of Medicine, Houston, Texas, USA
    Obesity (Silver Spring) 17:233-9. 2009
    ....
  19. pmc Contribution of galactose and fructose to glucose homeostasis
    Jorge A Coss-Bu
    Department of Pediatrics, Children s Nutrition Research Center, US Department of Agriculture Agricultural Research Service, Baylor College of Medicine, Houston, TX 77030, USA
    Metabolism 58:1050-8. 2009
    ..After the coingestion of fructose and glucose with the resultant insulin response from the glucose, fructose is a significant contributor to glycogen synthesis...
  20. ncbi request reprint Hexoneogenesis in the human breast during lactation
    Agneta L Sunehag
    Department of Pediatrics, Children s Nutrition Research Center, U S Department of Agriculture Agricultural Research Service, Baylor College of Medicine, Houston, Texas 77030, USA
    J Clin Endocrinol Metab 87:297-301. 2002
    ..In this process, glycerol is a precursor for milk galactose but not glucose...
  21. pmc Short-term effects of recombinant human growth hormone and feeding on gluconeogenesis in humans
    Walid Kaplan
    Children s Nutrition Research Center, Baylor College of Medicine, Houston, TX 77030 2600, USA
    Metabolism 57:725-32. 2008
    ..01) insulin sensitivity in both groups (P < .05). Gluconeogenesis is not affected by short-term increases in insulin and/or rhGH, which suggests a fundamental rethinking of the role of insulin in acutely regulating GNG...
  22. ncbi request reprint Splanchnic galactose extraction is regulated by coingestion of glucose in humans
    Agneta L Sunehag
    Department of Pediatrics, Children s Nutrition Research Center, USDA ARS, Baylor College of Medicine, Houston, TX 77030 2600, USA
    Metabolism 51:827-32. 2002
    ..We conclude that coingestion of glucose with galactose increases the splanchnic extraction, but decreases the conversion of galactose to glucose...
  23. doi request reprint A 12-week aerobic exercise program reduces hepatic fat accumulation and insulin resistance in obese, Hispanic adolescents
    Gert Jan van der Heijden
    Department of Pediatrics, Baylor College of Medicine, Houston, Texas, USA
    Obesity (Silver Spring) 18:384-90. 2010
    ..Thus, a controlled aerobic exercise program, without weight loss, reduced hepatic and visceral fat accumulation, and decreased insulin resistance in obese adolescents...
  24. ncbi request reprint Maternal protein homeostasis and milk protein synthesis during feeding and fasting in humans
    Agneta L Sunehag
    Children s Nutrition Research Center, 1100 Bates St, Houston, Texas 77030 2600, USA
    Am J Physiol Endocrinol Metab 285:E420-6. 2003
    ..We conclude that plasma free AA contribute only 70-80% of the substrate for milk protein synthesis in humans and that albumin may be a significant source of amino acids for the remainder...
  25. ncbi request reprint Subcutaneous infusion and capillary "finger stick" sampling of stable isotope tracer in metabolic studies
    Paula M Hertel
    Department of Pediatrics, Children s Nutrition Research Center, U S Department of Agriculture Agricultural Research Service, Baylor College of Medicine, Houston, Texas 77030, USA
    Pediatr Res 60:597-601. 2006
    ..In conclusion, subcutaneous infusion and finger stick specimen collection onto filter paper represent a potential method of conducting in vivo studies of substrate metabolism outside of a hospital-based research unit...
  26. pmc Twelve weeks of moderate aerobic exercise without dietary intervention or weight loss does not affect 24-h energy expenditure in lean and obese adolescents
    Gert Jan van der Heijden
    Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA
    Am J Clin Nutr 91:589-96. 2010
    ....
  27. ncbi request reprint Hyperglycemia is a risk factor for early death and morbidity in extremely low birth-weight infants
    Stephane P Hays
    USDA ARS Children s Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, 1100 Bates St, Houston, TX 77030, USA
    Pediatrics 118:1811-8. 2006
    ....

Research Grants13

  1. Regulation of Glucose Metabolism in Extremely Low Birth Weight (ELBW) Infants
    Agneta Sunehag; Fiscal Year: 2009
    ..A clear understanding of the mechanisms that control glucose homeostasis in the extremely low birth weight infant will permit us to develop evidence based strategies to maintain euglycemia while providing appropriate energy intake. ..
  2. Glucose & Lipid Metabolism in Obese Adolescents
    Agneta Sunehag; Fiscal Year: 2009
    ..This information is likely to lead to identifying factors and potentially new strategies to prevent and/or delay the onset of type 2 diabetes in adolescents. ..
  3. Regulation of Glucose Metabolism in Extremely Low Birth Weight (ELBW) Infants
    Agneta Sunehag; Fiscal Year: 2007
    ..A clear understanding of the mechanisms that control glucose homeostasis in the extremely low birth weight infant will permit us to develop evidence based strategies to maintain euglycemia while providing appropriate energy intake. ..
  4. GLUCONEOGENESIS IN VERY LOW BIRTH WEIGHT INFANTS
    Agneta Sunehag; Fiscal Year: 2004
    ..abstract_text> ..
  5. Regulation of Glucose Metabolism in Extremely Low Birth Weight (ELBW) Infants
    AGNETA LISBETH SUNEHAG; Fiscal Year: 2010
    ..A clear understanding of the mechanisms that control glucose homeostasis in the extremely low birth weight infant will permit us to develop evidence based strategies to maintain euglycemia while providing appropriate energy intake. ..