Rita E Serda

Summary

Affiliation: Texas Medical Center
Country: USA

Publications

  1. pmc Logic-embedded vectors for intracellular partitioning, endosomal escape, and exocytosis of nanoparticles
    Rita E Serda
    Department of Nanomedicine and BioMedical Engineering, University of Texas Health Science Center, 1825 Pressler Street, Suite 537, Houston, TX 77030, USA
    Small 6:2691-700. 2010
  2. ncbi request reprint Targeting and cellular trafficking of magnetic nanoparticles for prostate cancer imaging
    Rita E Serda
    Department of Biochemistry and Molecular Biology, University of New Mexico School of Medicine, Albuquerque, NM, USA
    Mol Imaging 6:277-88. 2007
  3. doi request reprint 1alpha,25-Dihydroxyvitamin D3 down-regulates expression of prostate specific membrane antigen in prostate cancer cells
    Rita E Serda
    Brown Institute of Molecular Medicine, University of Texas Health Science Center, Houston, Texas 77030, USA
    Prostate 68:773-83. 2008
  4. doi request reprint The association of silicon microparticles with endothelial cells in drug delivery to the vasculature
    Rita E Serda
    Brown Institute of Molecular Medicine, University of Texas Health Science Center, Nanomedicine Division, 1825 Pressler, Suite 537, Houston, TX 77030, USA
    Biomaterials 30:2440-8. 2009
  5. pmc Quantitative mechanics of endothelial phagocytosis of silicon microparticles
    Rita E Serda
    Division of NanoMedicine, Department of Biomedical Engineering, University of Texas Health Science Center, Houston, Texas 77030, USA
    Cytometry A 75:752-60. 2009
  6. pmc Cellular association and assembly of a multistage delivery system
    Rita E Serda
    Department of Nanomedicine and BioMedical Engineering, University of Texas Health Science Center UTHSC, Houston, TX 77030, USA
    Small 6:1329-40. 2010
  7. pmc Multi-stage delivery nano-particle systems for therapeutic applications
    Rita E Serda
    University of Texas Health Science Center, Department of Nanomedicine and BioMedical Engineering, 1825 Pressler, Suite 537, Houston, TX 77030, USA
    Biochim Biophys Acta 1810:317-29. 2011
  8. pmc Mitotic trafficking of silicon microparticles
    Rita E Serda
    University of Texas Health Science Center, Department of Nanomedicine and BioMedical Engineering, 1825 Pressler, Suite 537, Houston, TX 77030, USA
    Nanoscale 1:250-9. 2009
  9. pmc Tailoring the degradation kinetics of mesoporous silicon structures through PEGylation
    Biana Godin
    Department of Nanomedicine and BioMedical Engineering, School of Medicine, University of Texas Health Science Center at Houston, Houston, Texas 77030, USA
    J Biomed Mater Res A 94:1236-43. 2010
  10. pmc Intracellular trafficking of silicon particles and logic-embedded vectors
    Silvia Ferrati
    University of Texas Health Science Center, Department of Nanomedicine and BioMedical Engineering, 1825 Pressler Street, Suite 537, Houston, TX 77030, USA
    Nanoscale 2:1512-20. 2010

Collaborators

Detail Information

Publications22

  1. pmc Logic-embedded vectors for intracellular partitioning, endosomal escape, and exocytosis of nanoparticles
    Rita E Serda
    Department of Nanomedicine and BioMedical Engineering, University of Texas Health Science Center, 1825 Pressler Street, Suite 537, Houston, TX 77030, USA
    Small 6:2691-700. 2010
    ..Thus, LEVs provide a mechanism for shielded transport of nanoparticles to the lesion, cellular manipulation at multiple levels, and a means for targeting both within and between cells...
  2. ncbi request reprint Targeting and cellular trafficking of magnetic nanoparticles for prostate cancer imaging
    Rita E Serda
    Department of Biochemistry and Molecular Biology, University of New Mexico School of Medicine, Albuquerque, NM, USA
    Mol Imaging 6:277-88. 2007
    ..Our findings indicate that targeting prostate cancer cells using PSMA offers a specific and sensitive technique for enhancing MR images...
  3. doi request reprint 1alpha,25-Dihydroxyvitamin D3 down-regulates expression of prostate specific membrane antigen in prostate cancer cells
    Rita E Serda
    Brown Institute of Molecular Medicine, University of Texas Health Science Center, Houston, Texas 77030, USA
    Prostate 68:773-83. 2008
    ..Since PSMA is positively correlated with both of these characteristics, we hypothesized that 1,25-VD would regulate PSMA expression...
  4. doi request reprint The association of silicon microparticles with endothelial cells in drug delivery to the vasculature
    Rita E Serda
    Brown Institute of Molecular Medicine, University of Texas Health Science Center, Nanomedicine Division, 1825 Pressler, Suite 537, Houston, TX 77030, USA
    Biomaterials 30:2440-8. 2009
    ..These findings suggest that it may be possible to bioengineer silicon microparticles to favor opsonization with proteins that enhance uptake by endothelial cells, without a concurrent enhanced uptake by macrophages...
  5. pmc Quantitative mechanics of endothelial phagocytosis of silicon microparticles
    Rita E Serda
    Division of NanoMedicine, Department of Biomedical Engineering, University of Texas Health Science Center, Houston, Texas 77030, USA
    Cytometry A 75:752-60. 2009
    ..The resulting half-time for microparticle internalization was 15.7 min, with confirmation provided by live confocal imaging as well as transmission electron microscopy...
  6. pmc Cellular association and assembly of a multistage delivery system
    Rita E Serda
    Department of Nanomedicine and BioMedical Engineering, University of Texas Health Science Center UTHSC, Houston, TX 77030, USA
    Small 6:1329-40. 2010
    ..This study demonstrates the assembly and cellular association of a multiparticle delivery system that is biomolecularly targeted and has potential for applications in biological imaging...
  7. pmc Multi-stage delivery nano-particle systems for therapeutic applications
    Rita E Serda
    University of Texas Health Science Center, Department of Nanomedicine and BioMedical Engineering, 1825 Pressler, Suite 537, Houston, TX 77030, USA
    Biochim Biophys Acta 1810:317-29. 2011
    ..The progressive evolution of nanovectors has led to the development of multi-stage delivery systems aimed at overcoming the numerous obstacles encountered by nanovectors on their journey to the target site...
  8. pmc Mitotic trafficking of silicon microparticles
    Rita E Serda
    University of Texas Health Science Center, Department of Nanomedicine and BioMedical Engineering, 1825 Pressler, Suite 537, Houston, TX 77030, USA
    Nanoscale 1:250-9. 2009
    ..The finding that mitotic sorting of endosomes is unencumbered by the presence of nanoporous silicon microparticles advocates the use of silicon microparticles for biomedical applications...
  9. pmc Tailoring the degradation kinetics of mesoporous silicon structures through PEGylation
    Biana Godin
    Department of Nanomedicine and BioMedical Engineering, School of Medicine, University of Texas Health Science Center at Houston, Houston, Texas 77030, USA
    J Biomed Mater Res A 94:1236-43. 2010
    ....
  10. pmc Intracellular trafficking of silicon particles and logic-embedded vectors
    Silvia Ferrati
    University of Texas Health Science Center, Department of Nanomedicine and BioMedical Engineering, 1825 Pressler Street, Suite 537, Houston, TX 77030, USA
    Nanoscale 2:1512-20. 2010
    ..These results reinforce the concept of multi-functional nanocarriers, in which different particles are able to perform specific tasks, in order to deliver single- or multi-component payloads to specific sub-cellular compartments...
  11. ncbi request reprint Drug delivery: Logic-Embedded Vectors for Intracellular Partitioning, Endosomal Escape, and Exocytosis of Nanoparticles (Small 23/2010)
    Rita E Serda
    Department of Nanomedicine and BioMedical Engineering, University of Texas Health Science Center, 1825 Pressler Street, Suite 537, Houston, TX 77030, USA
    Small 6:2690. 2010
    ..Thus, LEVs provide a mechanism for shielded transport of nanoparticles to the lesion, cellular manipulation at multiple levels, and a means for targeting both within and between cells...
  12. pmc Multistage nanovectors: from concept to novel imaging contrast agents and therapeutics
    Biana Godin
    Department of Nanomedicine, The Methodist Hospital Research Institute, Houston, Texas 77030, USA
    Acc Chem Res 44:979-89. 2011
    ..We envision that the versatility of the MSV platform and its emerging properties will enable the creation of personalized solutions with broad clinical implications within and beyond the realm of cancer theranostics...
  13. pmc Preparation, characterization, and cellular associations of silicon logic-embedded vectors
    Anne L van de Ven
    Department of Nanomedicine, The Methodist Hospital Research Institute, Houston, Texas, USA
    Methods Enzymol 508:1-16. 2012
    ..A specific example of LEV fabrication from start to finish, along with optimization and troubleshooting information, is presented to serve as a template for future designs...
  14. pmc Enabling individualized therapy through nanotechnology
    Jason H Sakamoto
    The University of Texas Health Science Center, Department of Nanomedicine and BioMedical Engineering, Houston, TX 77030, USA
    Pharmacol Res 62:57-89. 2010
    ....
  15. doi request reprint Inter-endothelial transport of microvectors using cellular shuttles and tunneling nanotubes
    Silvia Ferrati
    Department of Nanomedicine, The Methodist Hospital Research Institute, Houston, TX 77030, USA
    Small 8:3151-60. 2012
    ..The opportunity to use microparticles to study cellular transfer events and biological triggers that induce these events may aid in the discovery of therapeutics that limit the spread of disease...
  16. ncbi request reprint Proteomic analysis of serum opsonins impacting biodistribution and cellular association of porous silicon microparticles
    Rita E Serda
    Department of Nanomedicine and BioMedical Engineering, University of Texas Health Science Center, Houston, TX 77030, USA
    Mol Imaging 10:43-55. 2011
    ..In summary, particle surface chemistry drives selective binding of serum components impacting cellular interactions and biodistribution...
  17. pmc The physiology of cardiovascular disease and innovative liposomal platforms for therapy
    Guillermo U Ruiz-Esparza
    Methodist Hospital Research Institute, Houston, TX, USA
    Int J Nanomedicine 8:629-40. 2013
    ..Potential pathological targets for therapy are introduced, and promising advances in nanotherapeutic cardiovascular applications involving liposomal platforms are presented...
  18. pmc Geometrical confinement of gadolinium-based contrast agents in nanoporous particles enhances T1 contrast
    Jeyarama S Ananta
    Department of Chemistry, Smalley Institute for Nanoscale Science and Technology, Center for Biological and Environmental Nanotechnology, Rice University, Houston, Texas 77251 1892, USA
    Nat Nanotechnol 5:815-21. 2010
    ..Thus, nanoscale confinement offers a new and general strategy for enhancing the contrast of gadolinium-based contrast agents...
  19. doi request reprint Activation of the inflammasome and enhanced migration of microparticle-stimulated dendritic cells to the draining lymph node
    Ismail M Meraz
    Department of Nanomedicine and Department of Systems Medicine and Bioengineering, The Methodist Hospital Research Institute, 6670 Bertner Avenue, Houston, Texas 77030, United States
    Mol Pharm 9:2049-62. 2012
    ....
  20. pmc Emerging applications of nanomedicine for the diagnosis and treatment of cardiovascular diseases
    Biana Godin
    Department of Nanomedicine and BioMedical Engineering, The University of Texas Health Science Center at Houston, 1825 Pressler, Suite 537, Houston, TX 77030, USA
    Trends Pharmacol Sci 31:199-205. 2010
    ..Specifically, we discuss the use of nanoparticles for molecular imaging and advanced therapeutics, specially designed drug eluting stents and in vivo/ex vivo early detection techniques...
  21. pmc Porous silicon advances in drug delivery and immunotherapy
    David J Savage
    Department of Nanomedicine, The Methodist Hospital Research Institute, 6670 Bertner Avenue, Houston, TX 77030, USA MD Anderson Cancer Center, Department of Surgical Oncology, 1515 Holcombe Blvd 444, Houston, TX, USA The University of Texas Medical School at Houston, 6431 Fannin, Houston, TX, USA
    Curr Opin Pharmacol 13:834-41. 2013
    ....
  22. ncbi request reprint 1H NMR Detection of superparamagnetic nanoparticles at 1T using a microcoil and novel tuning circuit
    Laurel O Sillerud
    Department of Biochemistry and Molecular Biology, University of New Mexico School of Medicine, Cancer Research and Treatment Center, Albuquerque, NM 87131, USA
    J Magn Reson 181:181-90. 2006
    ....