Research Topics
| Brandt L SchneiderSummaryAffiliation: Texas Tech University Health Sciences Center Country: USA Publications
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Detail Information
Publications
Destructive cycles: the role of genomic instability and adaptation in carcinogenesisBrandt L Schneider
Department of Cell Biology and Biochemistry, Room 5C119, Texas Tech University Health Sciences Center, 3601 4th Street, Lubbock, TX 79430, USA
Carcinogenesis 25:2033-44. 2004....
Growth rate and cell size modulate the synthesis of, and requirement for, G1-phase cyclins at startBrandt L Schneider
Department of Cell Biology and Biochemistry, Texas Tech University Health Sciences Center, 3601 4th St, Lubbock, TX 79430, USA
Mol Cell Biol 24:10802-13. 2004..Large cells generate more Cln1 or Cln2 protein for a given amount of CLN mRNA, suggesting the existence of a novel posttranscriptional size control mechanism...
Genomic scale mutant hunt identifies cell size homeostasis genes in S. cerevisiaeJian Zhang
Department of Cell Biology and Biochemistry, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA
Curr Biol 12:1992-2001. 2002..This genomic-wide genetic screen yielded 46 new cell size mutants and systematically assessed the effect of 5958 single gene deletions on cell size as cells exited the cell cycle...
Yeast cell synchronizationAudra Day
Department of Cell Biology and Biochemistry, Texas Tech University Health Sciences Center, Lubbock, USA
Methods Mol Biol 241:55-76. 2004
Ccr4 alters cell size in yeast by modulating the timing of CLN1 and CLN2 expressionArkadi Manukyan
Department of Cell Biology and Biochemistry, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA
Genetics 179:345-57. 2008..We find that Ccr4 negatively regulates the half-life of WHI5 mRNAs, and we conclude that, by modulating the stability of WHI5 mRNAs, Ccr4 influences the size-dependent timing of G1-phase cyclin transcription...
Cell size and Cln-Cdc28 complexes mediate entry into meiosis by modulating cell growthAudra Day
Department of Cell Biology and Biochemistry, Texas Tech University Health Sciences Center, Lubbock, Texas 79430, USA
Cell Cycle 3:1433-9. 2004..Finally, overexpression of CLNs repressed meiosis in smaller cells, but not in large cells. Taken together, these results demonstrate that Cln-Cdc28 represses entry into meiosis in part by inhibiting cell growth...
The importance of being bigJian Zhang
Department of Cell Biology and Biochemistry, Texas Tech University Health Sciences Center, Lubbock, Texas 79430, USA
J Investig Dermatol Symp Proc 10:131-41. 2005..The elucidation of this relationship will help clarify the role of cell size in promoting proliferation in both normal and cancer cells...
Using the yeast genome-wide gene-deletion collection for systematic genetic screensJian Zhang
Department of Cell Biology and Biochemistry, Texas Tech University Health Sciences Center, Lubbock, USA
Methods Mol Biol 241:143-61. 2004
The CLN3/SWI6/CLN2 pathway and SNF1 act sequentially to regulate meiotic initiation in Saccharomyces cerevisiaeKedar Purnapatre
Division of Cell Biology and Biophysics, School of Biological Sciences, University of Missouri Kansas City, Kansas City, MO 64110 2499, USA
Genes Cells 7:675-91. 2002..Here we examine the pathway by which Cln3:Cdc28p represses IME1 and the relationship between Cln3:Cdc28p and Snf1p in this regulation...
The size of the nucleus increases as yeast cells growPaul Jorgensen
Department of Medical Genetics and Microbiology, University of Toronto, Toronto, ON M5S 1A8, Canada
Mol Biol Cell 18:3523-32. 2007..Nuclear expansion must now be factored into conceptual and mathematical models of budding yeast growth and division. These results raise questions as to the unknown force(s) that expand the nucleus as yeast cells grow...
Glucose induction pathway regulates meiosis in Saccharomyces cerevisiae in part by controlling turnover of Ime2p meiotic kinaseMisa Gray
Division of Cell Biology and Biophysics, School of Biological Sciences, University of Missouri Kansas City, Kansas City, MO 64110 1270, USA
FEMS Yeast Res 8:676-84. 2008..Interestingly, Rgt1p was involved in glucose inhibition of spore formation but not inhibition of Ime2p stability. Thus, the glucose induction pathway may regulate meiosis through both RGT1-dependent and RGT1-independent pathways...
