Michael F Schmid

Summary

Affiliation: Texas Medical Center
Country: USA

Publications

  1. ncbi request reprint Cross-correlation and merging of crystallographic reflections derived from cryoelectron micrographs of 3D crystals: application to the Limulus acrosomal bundle
    Michael F Schmid
    Verna and Marrs McLean Department of Biochemistry and Molecular Biology and National Center for Macromolecular Imaging, Baylor College of Medicine, Houston, TX 77030, USA
    J Struct Biol 144:195-208. 2003
  2. pmc Methods for aligning and for averaging 3D volumes with missing data
    Michael F Schmid
    National Center for Macromolecular Imaging, Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA
    J Struct Biol 161:243-8. 2008
  3. pmc Crystallographic conformers of actin in a biologically active bundle of filaments
    Yao Cong
    National Center for Macromolecular Imaging and Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA
    J Mol Biol 375:331-6. 2008
  4. pmc Structural basis for scaffolding-mediated assembly and maturation of a dsDNA virus
    Dong Hua Chen
    National Center for Macromolecular Imaging, Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA
    Proc Natl Acad Sci U S A 108:1355-60. 2011
  5. pmc Visualizing virus assembly intermediates inside marine cyanobacteria
    Wei Dai
    National Center for Macromolecular Imaging, Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas 77030, USA
    Nature 502:707-10. 2013
  6. pmc Zernike phase contrast cryo-electron microscopy and tomography for structure determination at nanometer and subnanometer resolutions
    Kazuyoshi Murata
    National Center for Macromolecular Imaging, Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA
    Structure 18:903-12. 2010
  7. ncbi request reprint Structure of the acrosomal bundle
    Michael F Schmid
    National Center for Macromolecular Imaging, Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas 77030, USA
    Nature 431:104-7. 2004
  8. pmc A tail-like assembly at the portal vertex in intact herpes simplex type-1 virions
    Michael F Schmid
    National Center for Macromolecular Imaging, Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas, United States of America
    PLoS Pathog 8:e1002961. 2012
  9. pmc An atomic model of brome mosaic virus using direct electron detection and real-space optimization
    Zhao Wang
    1 National Center for Macromolecular Imaging, Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas 77030, USA 2
    Nat Commun 5:4808. 2014
  10. pmc Zernike phase-contrast electron cryotomography applied to marine cyanobacteria infected with cyanophages
    Wei Dai
    National Center for Macromolecular Imaging, Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas, USA
    Nat Protoc 9:2630-42. 2014

Collaborators

Detail Information

Publications29

  1. ncbi request reprint Cross-correlation and merging of crystallographic reflections derived from cryoelectron micrographs of 3D crystals: application to the Limulus acrosomal bundle
    Michael F Schmid
    Verna and Marrs McLean Department of Biochemistry and Molecular Biology and National Center for Macromolecular Imaging, Baylor College of Medicine, Houston, TX 77030, USA
    J Struct Biol 144:195-208. 2003
    ..5A resolution is evaluated for coherence. General issues such as statistical significance of cross-correlation function peaks, symmetry evaluation, and phase coherence as a function of amplitude are discussed...
  2. pmc Methods for aligning and for averaging 3D volumes with missing data
    Michael F Schmid
    National Center for Macromolecular Imaging, Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA
    J Struct Biol 161:243-8. 2008
    ..81, 2065-2068; Schmid, M.F., Paredes, A.M., Khant, H.A., Soyer, F., Aldrich, H.C., Chiu, W., and Shively, J.M., 2006. Structure of Halothiobacillus neapolitanus carboxysomes by cryo-electron tomography. J. Mol. Biol. 364, 526-535]...
  3. pmc Crystallographic conformers of actin in a biologically active bundle of filaments
    Yao Cong
    National Center for Macromolecular Imaging and Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA
    J Mol Biol 375:331-6. 2008
    ..The scruin and bundle packing forces appear to influence the tertiary and quaternary conformations of actin in the filament of this biologically active bundle...
  4. pmc Structural basis for scaffolding-mediated assembly and maturation of a dsDNA virus
    Dong Hua Chen
    National Center for Macromolecular Imaging, Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA
    Proc Natl Acad Sci U S A 108:1355-60. 2011
    ....
  5. pmc Visualizing virus assembly intermediates inside marine cyanobacteria
    Wei Dai
    National Center for Macromolecular Imaging, Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas 77030, USA
    Nature 502:707-10. 2013
    ..The morphogenetic pathway we describe here is highly conserved and was probably established long before that of double-stranded DNA viruses infecting more complex organisms. ..
  6. pmc Zernike phase contrast cryo-electron microscopy and tomography for structure determination at nanometer and subnanometer resolutions
    Kazuyoshi Murata
    National Center for Macromolecular Imaging, Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA
    Structure 18:903-12. 2010
    ..These results show quantitatively the benefits of ZPC-cryoEM and ZPC-cryoET for structural determinations of macromolecular machines at nanometer and subnanometer resolutions...
  7. ncbi request reprint Structure of the acrosomal bundle
    Michael F Schmid
    National Center for Macromolecular Imaging, Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas 77030, USA
    Nature 431:104-7. 2004
    ....
  8. pmc A tail-like assembly at the portal vertex in intact herpes simplex type-1 virions
    Michael F Schmid
    National Center for Macromolecular Imaging, Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas, United States of America
    PLoS Pathog 8:e1002961. 2012
    ..The location of this assembly suggests that it plays a role in genome release into the nucleus and is also important for virion architecture...
  9. pmc An atomic model of brome mosaic virus using direct electron detection and real-space optimization
    Zhao Wang
    1 National Center for Macromolecular Imaging, Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas 77030, USA 2
    Nat Commun 5:4808. 2014
    ..This study demonstrates a practical approach to obtain a rigorously validated atomic resolution electron cryo-microscopy structure. ..
  10. pmc Zernike phase-contrast electron cryotomography applied to marine cyanobacteria infected with cyanophages
    Wei Dai
    National Center for Macromolecular Imaging, Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas, USA
    Nat Protoc 9:2630-42. 2014
    ..We expect this time requirement to decrease substantially as the technique matures. The time required for annotation and subtomogram averaging varies widely depending on the project goals and data volume. ..
  11. pmc Principles of virus structural organization
    B V Venkataram Prasad
    Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA
    Adv Exp Med Biol 726:17-47. 2012
    ..In this chapter, we review principles underlying capsid formation in a variety of viruses, emphasizing the recent developments along with some historical perspective...
  12. pmc Symmetry-free cryo-EM structures of the chaperonin TRiC along its ATPase-driven conformational cycle
    Yao Cong
    Verna and Marrs McLean Department of Biochemistry and Molecular Biology, National Center for Macromolecular Imaging, Baylor College of Medicine, Houston, TX 77030, USA
    EMBO J 31:720-30. 2012
    ..Intriguingly, these mechanisms are different from other group I and II chaperonins despite their similar architecture...
  13. pmc Modular software platform for low-dose electron microscopy and tomography
    Michael P Marsh
    Graduate Program in Structural and Computational Biology and Molecular Biophysics, and National Center for Macromolecular Imaging, Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA
    J Microsc 228:384-9. 2007
    ..Both applications have been widely used within our NCRR-supported Center for routine data collection and are now made available for public download...
  14. pmc Domain organization and conformational plasticity of the G protein effector, PDE6
    Zhixian Zhang
    From the Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas 77030 and
    J Biol Chem 290:12833-43. 2015
    ..Removal of PDE6γ caused dramatic structural rearrangements, which were reversed upon its restoration. ..
  15. pmc Structural Mechanisms of Mutant Huntingtin Aggregation Suppression by the Synthetic Chaperonin-like CCT5 Complex Explained by Cryoelectron Tomography
    Michele C Darrow
    From the National Center for Macromolecular Imaging, Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas 77030
    J Biol Chem 290:17451-61. 2015
    ....
  16. pmc TRiC's tricks inhibit huntingtin aggregation
    Sarah H Shahmoradian
    Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, United States National Center for Macromolecular Imaging, and the Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, United States
    elife 2:e00710. 2013
    ..These two complementary mechanisms provide a structural description for TRiC's inhibition of mhttQ51 aggregation in vitro. DOI:http://dx.doi.org/10.7554/eLife.00710.001. ..
  17. pmc Structural changes in a marine podovirus associated with release of its genome into Prochlorococcus
    Xiangan Liu
    National Center for Macromolecular Imaging, Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas, USA
    Nat Struct Mol Biol 17:830-6. 2010
    ..Our observations suggest a mechanism whereby, upon binding to the host cell, the tail fibers induce a cascade of structural alterations of the portal vertex complex that triggers DNA release...
  18. ncbi request reprint Electron cryomicroscopy of biological machines at subnanometer resolution
    Wah Chiu
    National Center for Macromolecular Imaging, Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas 77030, USA
    Structure 13:363-72. 2005
    ..The consequences of these analyses can not only identify accurately some of the secondary structure elements of the molecular components in machines but also suggest structural mechanisms related to their biological functions...
  19. pmc Structure of Halothiobacillus neapolitanus carboxysomes by cryo-electron tomography
    Michael F Schmid
    National Center for Macromolecular Imaging, Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA
    J Mol Biol 364:526-35. 2006
    ..The averages reveal icosahedral symmetry of the shell, but not of the density inside it, for all the size classes...
  20. pmc Electron cryotomography reveals the portal in the herpesvirus capsid
    Juan T Chang
    Graduate Program in Structural and Computational Biology and Molecular Biophysics, National Center for Macromolecular Imaging, Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA
    J Virol 81:2065-8. 2007
    ..Such similarity in portal organization supports the idea of the evolutionary relatedness of these viruses...
  21. pmc Structure of Trypanosoma brucei flagellum accounts for its bihelical motion
    Alexey Y Koyfman
    National Center for Macromolecular Imaging, Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA
    Proc Natl Acad Sci U S A 108:11105-8. 2011
    ..We propose that the PFR modifies the in-plane axoneme motion to produce the characteristic trypanosome bihelical motility as captured by high-speed light microscope videography...
  22. pmc Visualizing the structural changes of bacteriophage Epsilon15 and its Salmonella host during infection
    Juan T Chang
    National Center for Macromolecular Imaging, Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA
    J Mol Biol 402:731-40. 2010
    ..This tube would direct the DNA into the cytoplasm and protect it from periplasmic nucleases. Once the DNA has been injected into the cell, the tube and portal seals, and the empty bacteriophage remains at the cell surface...
  23. pmc Structure of a biologically active estrogen receptor-coactivator complex on DNA
    Ping Yi
    Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA Clayton Foundation for Research, Houston, TX 77056, USA
    Mol Cell 57:1047-58. 2015
    ..We also present structural evidence for the location of activation function 1 (AF-1) in a full-length nuclear receptor, which supports a role for AF-1 in SRC-3 recruitment. ..
  24. pmc Achievable resolution from images of biological specimens acquired from a 4k x 4k CCD camera in a 300-kV electron cryomicroscope
    Dong Hua Chen
    National Center for Macromolecular Imaging, Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA
    J Struct Biol 163:45-52. 2008
    ....
  25. pmc Interprotofilament interactions between Alzheimer's Abeta1-42 peptides in amyloid fibrils revealed by cryoEM
    Rui Zhang
    Graduate Program in Structural and Computational Biology and Molecular Biophysics, Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA
    Proc Natl Acad Sci U S A 106:4653-8. 2009
    ..In our model, the C terminus of Abeta forms the inside wall of the hollow core, which is supported by partial proteolysis analysis...
  26. pmc Radiation damage effects at four specimen temperatures from 4 to 100 K
    Benjamin E Bammes
    National Center for Macromolecular Imaging, Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA
    J Struct Biol 169:331-41. 2010
    ..At lower resolution, suitable for tomography, intermediate temperatures (25 or 42K) may provide a modest improvement in cryo-protection without introducing deleterious effects evident at 4 K...
  27. pmc Lemon-shaped halo archaeal virus His1 with uniform tail but variable capsid structure
    Chuan Hong
    Graduate Program in Structural and Computational Biology and Molecular Biophysics, Baylor College of Medicine, Houston, TX 77030 National Center for Macromolecular Imaging, Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030 and
    Proc Natl Acad Sci U S A 112:2449-54. 2015
    ..Such a dramatic transformation demonstrates that the capsid proteins are capable of undergoing substantial quaternary structural changes, which may occur at different stages of the virus life cycle. ..
  28. doi request reprint Single-particle electron cryotomography (cryoET)
    Michael F Schmid
    Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas, USA
    Adv Protein Chem Struct Biol 82:37-65. 2011
    ..It also reviews applications of the inverse problem, that of orienting a template back into a tomogram, to determine the position of a molecule in the context of a whole cell...
  29. ncbi request reprint How a G protein binds a membrane
    Zhixian Zhang
    Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas 77030, USA
    J Biol Chem 279:33937-45. 2004
    ..The narrowness of the tethers to the lipid bilayer provides flexibility for the protein to adopt multiple orientations on the membrane, and leaves most of the G protein surface area available for protein-protein interactions...