Jeffrey Rogers

Summary

Affiliation: Texas Medical Center
Country: USA

Publications

  1. pmc CRHR1 genotypes, neural circuits and the diathesis for anxiety and depression
    J Rogers
    Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA
    Mol Psychiatry 18:700-7. 2013
  2. pmc On the genetic architecture of cortical folding and brain volume in primates
    Jeffrey Rogers
    Department of Genetics, Southwest Foundation for Biomedical Research, 7620 N W Loop 410, San Antonio, TX 78227, USA
    Neuroimage 53:1103-8. 2010
  3. pmc Serum prostate specific antigen changes in cynomolgus monkeys (Macaca fascicularis) on a high sugar high fat diet
    James N Mubiru
    Southwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, TX 78245 0549, USA
    Prostate 72:469-75. 2012
  4. pmc Localization of multiple pleiotropic genes for lipoprotein metabolism in baboons
    David L Rainwater
    Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, TX 78245, USA
    J Lipid Res 50:1420-8. 2009
  5. pmc Nonhuman primates as models for studies of prostate specific antigen and prostatic diseases
    James N Mubiru
    Southwest National Primate Research Center, Southwest Foundation for Biomedical Research, San Antonio, Texas 78245 0549, USA
    Prostate 68:1546-54. 2008
  6. ncbi request reprint An initial genetic linkage map of the rhesus macaque (Macaca mulatta) genome using human microsatellite loci
    Jeffrey Rogers
    Department of Genetics, Southwest Foundation for Biomedical Research, 7620 N W, Loop 410, San Antonio, TX 78227, USA
    Genomics 87:30-8. 2006
  7. ncbi request reprint Designing new microsatellite markers for linkage and population genetic analyses in rhesus macaques and other nonhuman primates
    Muthuswamy Raveendran
    Department of Genetics, Southwest Foundation for Biomedical Research, P O Box 760549, San Antonio, TX 78227, USA
    Genomics 88:706-10. 2006
  8. pmc Genotype-by-diet effects on co-variation in Lp-PLA2 activity and LDL-cholesterol concentration in baboons fed an atherogenic diet
    Amanda Vinson
    Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, TX, USA
    J Lipid Res 49:1295-302. 2008
  9. ncbi request reprint A second-generation genetic linkage map of the baboon (Papio hamadryas) genome
    Laura A Cox
    Department of Genetics and Southwest National Primate Research Center, Southwest Foundation for Biomedical Research, 7620 NW Loop 410, San Antonio, TX 78227, USA
    Genomics 88:274-81. 2006
  10. ncbi request reprint Localization of genes that control LDL size fractions in baboons
    David L Rainwater
    Department of Genetics, Southwest Foundation for Biomedical Research, P O Box 760549, San Antonio, TX 78245 0549, USA
    Atherosclerosis 168:15-22. 2003

Research Grants

Detail Information

Publications29

  1. pmc CRHR1 genotypes, neural circuits and the diathesis for anxiety and depression
    J Rogers
    Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA
    Mol Psychiatry 18:700-7. 2013
    ..These results suggest that variation in CRHR1 may influence brain function before any childhood adversity and may be a diathesis for the interaction between CRHR1 genotypes and childhood trauma reported to affect human psychopathology...
  2. pmc On the genetic architecture of cortical folding and brain volume in primates
    Jeffrey Rogers
    Department of Genetics, Southwest Foundation for Biomedical Research, 7620 N W Loop 410, San Antonio, TX 78227, USA
    Neuroimage 53:1103-8. 2010
    ..These results provide initial evidence for the heritability of gyrification, and possibly a new perspective on the evolutionary mechanisms underlying long-term changes in the nonhuman primate and human brain...
  3. pmc Serum prostate specific antigen changes in cynomolgus monkeys (Macaca fascicularis) on a high sugar high fat diet
    James N Mubiru
    Southwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, TX 78245 0549, USA
    Prostate 72:469-75. 2012
    ..An inverse relationship between serum prostate specific antigen (PSA) levels and body mass index (BMI) has been reported in men but not in any animal model...
  4. pmc Localization of multiple pleiotropic genes for lipoprotein metabolism in baboons
    David L Rainwater
    Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, TX 78245, USA
    J Lipid Res 50:1420-8. 2009
    ..Confirming the value of this approach, three of the QTL clusters replicated published linkage findings for the same or similar traits...
  5. pmc Nonhuman primates as models for studies of prostate specific antigen and prostatic diseases
    James N Mubiru
    Southwest National Primate Research Center, Southwest Foundation for Biomedical Research, San Antonio, Texas 78245 0549, USA
    Prostate 68:1546-54. 2008
    ..However, PSA has clinical limitations as a screen for prostatic diseases due to its low sensitivity and specificity. There is a strong need to better understand the biology of PSA and factors affecting its serum levels...
  6. ncbi request reprint An initial genetic linkage map of the rhesus macaque (Macaca mulatta) genome using human microsatellite loci
    Jeffrey Rogers
    Department of Genetics, Southwest Foundation for Biomedical Research, 7620 N W, Loop 410, San Antonio, TX 78227, USA
    Genomics 87:30-8. 2006
    ....
  7. ncbi request reprint Designing new microsatellite markers for linkage and population genetic analyses in rhesus macaques and other nonhuman primates
    Muthuswamy Raveendran
    Department of Genetics, Southwest Foundation for Biomedical Research, P O Box 760549, San Antonio, TX 78227, USA
    Genomics 88:706-10. 2006
    ..Finally, we propose a nomenclature system that can be used for rhesus-derived microsatellites genotyped in any species or for novel loci derived from the genome sequence of any nonhuman primate...
  8. pmc Genotype-by-diet effects on co-variation in Lp-PLA2 activity and LDL-cholesterol concentration in baboons fed an atherogenic diet
    Amanda Vinson
    Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, TX, USA
    J Lipid Res 49:1295-302. 2008
    ..We conclude that the pleiotropic QTLs detected at 2p24.3-p23.2 and 19q12-q13.2 on the basal and HCHF diets, respectively, exert diet-specific effects on covariation in Lp-PLA(2) activity and LDL-C concentration...
  9. ncbi request reprint A second-generation genetic linkage map of the baboon (Papio hamadryas) genome
    Laura A Cox
    Department of Genetics and Southwest National Primate Research Center, Southwest Foundation for Biomedical Research, 7620 NW Loop 410, San Antonio, TX 78227, USA
    Genomics 88:274-81. 2006
    ..We report in detail on baboon chromosomes 5, 12, and 18 for which the linkage maps are now substantially improved due to addition of new informative markers...
  10. ncbi request reprint Localization of genes that control LDL size fractions in baboons
    David L Rainwater
    Department of Genetics, Southwest Foundation for Biomedical Research, P O Box 760549, San Antonio, TX 78245 0549, USA
    Atherosclerosis 168:15-22. 2003
    ..15) on the baboon homologue of human chromosome 16. Thus, we have evidence for three putative QTLs that influence variation in baboon LDL size phenotypes on different diets...
  11. ncbi request reprint Determinants of variation in serum paraoxonase enzyme activity in baboons
    David L Rainwater
    Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, TX 78245, USA
    J Lipid Res 46:1450-6. 2005
    ....
  12. ncbi request reprint Quantitative trait loci for peripheral blood cell counts: a study in baboons
    Angéline Bertin
    Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, Texas 78245 0549, USA
    Mamm Genome 18:361-72. 2007
    ..Future studies should help identify the genes responsible for these QTL and elucidate their role on baseline variation in hematologic indicators of health and disease...
  13. ncbi request reprint QTL with pleiotropic effects on serum levels of bone-specific alkaline phosphatase and osteocalcin maps to the baboon ortholog of human chromosome 6p23-21.3
    Lorena M Havill
    Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, Texas 78245 0549, USA
    J Bone Miner Res 21:1888-96. 2006
    ..3 that accounts for 25% (bone ALP) and 20% (OC) of the genetic variance. A gene affecting osteoblast activity, number, or recruitment likely resides in this area...
  14. pmc Androgen receptor CAG repeat polymorphism in males of six non-human primate species
    James N Mubiru
    Southwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, TX, USA
    J Med Primatol 41:67-70. 2012
    ..Androgen receptor [CAG](n) microsatellite has been linked to human diseases...
  15. ncbi request reprint Heritability of brain volume, surface area and shape: an MRI study in an extended pedigree of baboons
    Jeffrey Rogers
    Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, Texas 78227, USA
    Hum Brain Mapp 28:576-83. 2007
    ....
  16. ncbi request reprint A panel of 20 highly variable microsatellite polymorphisms in rhesus macaques (Macaca mulatta) selected for pedigree or population genetic analysis
    Jeffrey Rogers
    Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, Texas 78227, USA
    Am J Primatol 67:377-83. 2005
    ..Many of these loci are also likely to be informative in other closely related Old World monkey species...
  17. ncbi request reprint Quantitative genetic analysis of glucose transporter 4 mRNA levels in baboon adipose
    M Elizabeth Tejero
    Department of Genetics, Southwest Foundation for Biomedical Research, 7620 NW Loop 410, San Antonio, TX 78227 5301, USA
    Obes Res 12:1652-7. 2004
    ..The objective was to conduct quantitative genetic analyses using GLUT4 mRNA levels in omental adipose tissue of baboons as a novel phenotype...
  18. pmc A preliminary report on the feeding of cynomolgus monkeys (Macaca fascicularis) with a high-sugar high-fat diet for 33 weeks
    James N Mubiru
    Southwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, TX, USA
    J Med Primatol 40:335-41. 2011
    ..The metabolic syndrome is common in populations exposed to a typical Western diet. There is a lack of an animal model that mimics this condition...
  19. ncbi request reprint Trisomy 17 in a baboon (Papio hamadryas) with polydactyly, patent foramen ovale and pyelectasis
    Charleen M Moore
    Department of Cellular and Structural Biology, University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229 3900, USA
    Am J Primatol 69:1105-18. 2007
    ..This trisomy was, therefore, due to either an error in meiosis II or the result of postzygotic nondisjunction. The parental origin, however, could not be determined...
  20. ncbi request reprint Genetics of monoamine metabolites in baboons: overlapping sets of genes influence levels of 5-hydroxyindolacetic acid, 3-hydroxy-4-methoxyphenylglycol, and homovanillic acid
    Jeffrey Rogers
    Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, Texas 78227, USA
    Biol Psychiatry 55:739-44. 2004
    ..Further genetic analysis can help explain phenotypic correlations among monoamine levels and might eventually help identify genes involved in response to therapy or risk of psychopathology...
  21. pmc Genetic contributions to the midsagittal area of the corpus callosum
    Kimberley A Phillips
    Department of Psychology, Trinity University, San Antonio, TX, USA
    Twin Res Hum Genet 15:315-23. 2012
    ..Combined with previous research reporting high heritability of other brain structures in baboons, these results reveal a consistent pattern of high heritability for brain morphometric measures in baboons...
  22. ncbi request reprint A preliminary study of the baboon prostate pathophysiology
    James N Mubiru
    Southwest National Primate Research Center, Southwest Foundation for Biomedical Research, San Antonio, Texas 78227 5301, USA
    Prostate 67:1421-31. 2007
    ..At present there are no suitable animal models for these diseases. This study explores the potential use of the baboon as a model for prostatic diseases...
  23. ncbi request reprint Comparative primate genomics: emerging patterns of genome content and dynamics
    Jeffrey Rogers
    Human Genome Sequencing Center and Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030, USA
    Nat Rev Genet 15:347-59. 2014
    ..This Review summarizes current knowledge regarding primate genome content and dynamics, and proposes a series of goals for the near future. ..
  24. ncbi request reprint Evolutionary and biomedical insights from the rhesus macaque genome
    Richard A Gibbs
    Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA
    Science 316:222-34. 2007
    ..The complete description of the macaque genome blueprint enhances the utility of this animal model for biomedical research and improves our understanding of the basic biology of the species...
  25. pmc Evolutionary genetics and implications of small size and twinning in callitrichine primates
    R Alan Harris
    Departments of Obstetrics and Gynecology, Division of Maternal Fetal Medicine and Molecular and Human Genetics, Human Genome Sequencing Center, and Department of Molecular and Cell Biology and the Reproductive Medicine Center, Baylor College of Medicine, Houston, TX 77030
    Proc Natl Acad Sci U S A 111:1467-72. 2014
    ..We postulate that positive selection affected NWM growth patterns, with callitrichine miniaturization coevolving with a series of reproductive adaptations. ..
  26. pmc Characterization of single-nucleotide variation in Indian-origin rhesus macaques (Macaca mulatta)
    Gloria L Fawcett
    Department of Molecular and Human Genetics, Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas 77030, USA
    BMC Genomics 12:311. 2011
    ....
  27. ncbi request reprint A major gene influences variation in large HDL particles and their response to diet in baboons
    David L Rainwater
    Department of Genetics, Southwest Foundation for Biomedical Research, PO Box 760549, San Antonio, TX 78245 0549, USA
    Atherosclerosis 163:241-8. 2002
    ..Our results suggest this major gene in baboons plays a pivotal role in HDL metabolism, but is unlikely to code for any of the proteins previously implicated in studies of human HDL(1)...
  28. ncbi request reprint A male baboon (Papio hamadryas) with a mosaic 43,XXY/42,XY karyotype
    Christopher J Dudley
    Department of Obstetrics and Gynecology, University of Texas Health Science Center at San Antonio, San Antonio, TX 78227, USA
    Am J Med Genet A 140:94-7. 2006
  29. ncbi request reprint Mitochondrial phylogeny and systematics of baboons (Papio)
    Timothy K Newman
    Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, Texas 78227, USA
    Am J Phys Anthropol 124:17-27. 2004
    ..The overall phylogeny, when combined with paleontological data, suggests a southern African origin for extant Papio baboons, with all extant lineages sharing a common mitochondrial ancestor at approximately 1.8 Ma...

Research Grants30

  1. MOLECULAR GENETIC MARKERS IN PRIMATE DISEASE MODELS
    Jeffrey Rogers; Fiscal Year: 1999
    ....
  2. MOLECULAR GENETIC MARKERS IN PRIMATE DISEASE MODELS
    Jeffrey Rogers; Fiscal Year: 2004
    ..abstract_text> ..
  3. Genetics of Monoamine Endophenotypes and Mental Health
    Jeffrey Rogers; Fiscal Year: 2004
    ..e., temperament). Identification of these genes will be very significant for future studies of genetic risk factors for psychiatric illness in humans. ..
  4. Genetics of Monoamine Endophenotypes and Mental Health
    Jeffrey Rogers; Fiscal Year: 2005
    ..e., temperament). Identification of these genes will be very significant for future studies of genetic risk factors for psychiatric illness in humans. ..
  5. MOLECULAR GENETIC MARKERS IN PRIMATE DISEASE MODELS
    Jeffrey Rogers; Fiscal Year: 2005
    ..abstract_text> ..
  6. MOLECULAR GENETIC MARKERS IN PRIMATE DISEASE MODELS
    Jeffrey Rogers; Fiscal Year: 2004
    ..No Abstract Provided. ..
  7. Genetics of Monoamine Endophenotypes and Mental Health
    Jeffrey Rogers; Fiscal Year: 2004
    ..Abstract Not Provided. ..
  8. GENETIC LINKAGE MAPPING IN RHESUS MONKEYS
    Jeffrey Rogers; Fiscal Year: 2005
    ..e. QTL mapping analyses) intended to locate functional genes that influence significant traits related to human health and disease. ..
  9. Genetics of Monoamine Endophenotypes and Mental Health
    Jeffrey Rogers; Fiscal Year: 2006
    ..e., temperament). Identification of these genes will be very significant for future studies of genetic risk factors for psychiatric illness in humans. ..
  10. GENETIC LINKAGE MAPPING IN RHESUS MONKEYS
    Jeffrey Rogers; Fiscal Year: 2006
    ..e. QTL mapping analyses) intended to locate functional genes that influence significant traits related to human health and disease. ..
  11. GENETIC LINKAGE MAPPING IN RHESUS MONKEYS
    Jeffrey Rogers; Fiscal Year: 2007
    ..e. QTL mapping analyses) intended to locate functional genes that influence significant traits related to human health and disease. ..
  12. GENETIC LINKAGE MAPPING IN RHESUS MONKEYS
    Jeffrey Rogers; Fiscal Year: 2006
    ..e. QTL mapping analyses) intended to locate functional genes that influence significant traits related to human health and disease. ..
  13. MOLECULAR GENETIC MARKERS IN PRIMATE DISEASE MODELS
    Jeffrey Rogers; Fiscal Year: 2003
    ..abstract_text> ..
  14. GENETIC LINKAGE MAPPING IN RHESUS MONKEYS
    Jeffrey Rogers; Fiscal Year: 2003
    ..When completed, this project will provide valuable new genetic data and methods that will make more useful for wide range of biomedical research purposes. ..
  15. MOLECULAR GENETIC MARKERS IN PRIMATE DISEASE MODELS
    Jeffrey Rogers; Fiscal Year: 2000
    ....
  16. HERITABILITY OF MONAMINE METABOLITES & BEHAVIOR
    Jeffrey Rogers; Fiscal Year: 1999
    ....
  17. MOLECULAR GENETIC SERVICES
    Jeffrey Rogers; Fiscal Year: 1999
  18. MOLECULAR GENETIC MARKERS IN PRIMATE DISEASE MODELS
    Jeffrey Rogers; Fiscal Year: 2001
    ....
  19. GENETIC LINKAGE MAPPING IN RHESUS MONKEYS
    Jeffrey Rogers; Fiscal Year: 2001
    ..When completed, this project will provide valuable new genetic data and methods that will make more useful for wide range of biomedical research purposes. ..
  20. HERITABILITY OF MONAMINE METABOLITES & BEHAVIOR
    Jeffrey Rogers; Fiscal Year: 2001
    ....
  21. Genetics of Monoamine Endophenotypes and Mental Health
    Jeffrey Rogers; Fiscal Year: 2002
    ..e., temperament). Identification of these genes will be very significant for future studies of genetic risk factors for psychiatric illness in humans. ..
  22. MOLECULAR GENETIC MARKERS IN PRIMATE DISEASE MODELS
    Jeffrey Rogers; Fiscal Year: 2002
    ..abstract_text> ..
  23. GENETIC LINKAGE MAPPING IN RHESUS MONKEYS
    Jeffrey Rogers; Fiscal Year: 2002
    ..When completed, this project will provide valuable new genetic data and methods that will make more useful for wide range of biomedical research purposes. ..
  24. HERITABILITY OF MONAMINE METABOLITES & BEHAVIOR
    Jeffrey Rogers; Fiscal Year: 2002
    ....
  25. Genetics of Monoamine Endophenotypes and Mental Health
    Jeffrey Rogers; Fiscal Year: 2003
    ..e., temperament). Identification of these genes will be very significant for future studies of genetic risk factors for psychiatric illness in humans. ..